• Proceedings of the Korean Geotechical Society Conference
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• 2008.10a
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• pp.1285-1289
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• 2008

Increasing the flood control capacity's link that is enforcing to existing dam by unusual change of weather, While build planing construction by exiting spillway of tunnel type to dam, could know that part bed rock is formed as is different with design. Grasped topography of research area and geology state to definite distribution aspect of different bed rock, Place that achieved Surface geological Survey and correct Survey is difficult in some section enforced Electrical resistivity dipole-dipole investigation. Grasped stratigraphy distribution confirmation and fracture or weathering zone making out siding 2D-Resistivity Electrical resistivity diagram and Reverse analysis diagram, examining closely soil weathered rock rock's distribution state, established stability countermeasure plan

• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.146.1-146.1
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• 2012

BOAO/KASINICS를 이용한 다주기 변광성들의 적외선 광도곡선 분석 연구의 중간 결과이다. 대표적인 천체인 BL Cam은 SX Pho에 속하며 그 중 가장 짧은 주기로 변광하는 천체이며, 2010년 9월 26일부터 2011년 11월 15일 총 30여 시간 동안 J, H, 그리고 Ks 필터에서 시계열 관측 자료를 얻었고, Period04를 이용하여 주기광도분석을 하였다. 그 결과 $f_0$의 경우 기존 광학 연구의 결과와 매우 근사한 값을 보였고, $f_1$의 경우 Ks 필터 자료에서 36.2137 cycle/day의 값이 검출되었다. 또한, 25 cycle/day와 51 cycle/day 영역에서 여러 개의 파워가 밀집되어있는 미세변광현상이 측정되었다.

• Archives of Pharmacal Research
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• v.8 no.4
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• pp.267-272
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• 1985

Pyrantal pamoate's anthelmintic activity is due to its action as a neuromuscular blocking agent. It is generally well tolerated. Transient rises in SGOT levels have been reported in the drug-treated patients. Decreased levels of serum alkaline phosphatase post treatment were found in yound dogs. The present study was performed to investigate the possible toxic effects of pyrantal pamoate in pregnant mice progenies. The drug was given in different doses to these mothers in the first, second and third trimester. Serum alkaline phosphatase, SGOT and SGPT of one or two month old offspring were monitored. SGOT levels showed an increase in some doses in one and two month old offspring where alkaline phosphatase showed a decrease in some doses in one and two month old offspring. The latter effect may be due to osteoblastic alkaline phosphatase inhibition. The effect on SGOT levels, however, was difficult to explain, but may be due to a toxic effect on liver cells or cardiac muscles.

• Proceedings of the Korean Information Science Society Conference
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• 2007.06b
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• pp.152-155
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• 2007

본 논문은 교육 서비스의 안정적인 품질을 제공하고 개방된 외부 인터페이스를 통해 외부 LMS 등과도 연동이 손쉽게 되며 영상자료공유 연동을 통해 동영상에 대한 공유가 가능한 실시간 화상 외국어 교육 플랫폼에 관한 것으로 타 교육 솔루션보다 확장성, 안정성, 기능성 면에서 차별화 되는 특징을 가지며 사업 현실에 적용이 유리한 이점을 제공한다. 또한 3rd 파티 어플리케이션의 이식도 가능하여 새로운 번들형 서비스를 손쉽게 만들어 낼 수 있고 그 개발비용을 최소화 하여 유사 솔루션에 대한 가격 경쟁력을 확보할 수 있는 장점을 가진다.

• Journal of Microbiology
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• v.43 no.spc1
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• pp.85-92
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• 2005

An early step in the pathogenesis of non-typhoidal Salmonella species is the ability to penetrate the intestinal epithelial monolayer. This process of cell invasion requires the production and transport of secreted effector proteins by a type III secretion apparatus encoded in Salmonella pathogenicity island I (SPI-1). The control of invasion involves a number of genetic regulators and environmental stimuli in complex relationships. SPI-1 itself encodes several transcriptional regulators (HilA, HilD, HilC, and InvF) with overlapping sets of target genes. These regulators are, in turn, controlled by both positive and regulators outside SPI-1, including the two-component regulators BarA/SirA and PhoP/Q, and the csr post-transcriptional control system. Additionally, several environmental conditions are known to regulate invasion, including pH, osmolarity, oxygen tension, bile, $Mg^{2+}$ concentration, and short chain fatty acids. This review will discuss the current understanding of invasion control, with emphasis on the interaction of environmental factors with genetic regulators that leads to productive infection.

• Molecules and Cells
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• v.44 no.3
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• pp.179-185
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• 2021

Vancomycin response regulator (VncR) is a pneumococcal response regulator of the VncRS two-component signal transduction system (TCS) of Streptococcus pneumoniae. VncRS regulates bacterial autolysis and vancomycin resistance. VncR contains two different functional domains, the N-terminal receiver domain and C-terminal effector domain. Here, we investigated VncR C-terminal DNA binding domain (VncRc) structure using a crystallization approach. Crystallization was performed using the micro-batch method. The crystals diffracted to a 1.964 Å resolution and belonged to space group P212121. The crystal unit-cell parameters were a = 25.71 Å, b = 52.97 Å, and c = 60.61 Å. The structure of VncRc had a helix-turn-helix motif highly similar to the response regulator PhoB of Escherichia coli. In isothermal titration calorimetry and size exclusion chromatography results, VncR formed a complex with VncS, a sensor histidine kinase of pneumococcal TCS. Determination of VncR structure will provide insight into the mechanism by how VncR binds to target genes.

• Journal of Environmental Impact Assessment
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• v.24 no.2
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• pp.134-153
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• 2015

When making urban planning, it is important to understand climate effect caused by urban structural changes. Seoul city applies UPIS(Urban Plan Information System) which provides information on urban planning scenario. Technology for analyzing climate effect resulted from urban planning needs to developed by linking urban planning scenario provided by UPIS and climate analysis model, CAS(Climate Analysis Seoul). CAS develops for analyzing urban climate conditions to provide realistic information considering local air temperature and wind flows. Quantitative analyses conducted by CAS for the production, transportation, and stagnation of cold air, wind flow and thermal conditions by incorporating GIS analysis on land cover and elevation and meteorological analysis from MetPhoMod(Meteorology and atmospheric Photochemistry Meso-scale model). In order to reflect land cover and elevation of the latest information, CAS used to highly accurate raster data (1m) sourced from LiDAR survey and KOMPSAT-2(KOrea Multi-Purpose SATellite) satellite image(4m). For more realistic representation of land surface characteristic, DSM(Digital Surface Model) and DTM(Digital Terrain Model) data used as an input data for CFD(Computational Fluid Dynamics) model. Eight inflow directions considered to investigate the change of flow pattern, wind speed according to reconstruction and change of thermal environment by connecting green area formation. Also, MetPhoMod in CAS data used to consider realistic weather condition. The result show that wind corridors change due to reconstruction. As a whole surface temperature around target area decreases due to connecting green area formation. CFD model coupled with CAS is possible to evaluate the wind corridor and heat environment before/after reconstruction and connecting green area formation. In This study, analysis of climate impact before and after created the green area, which is part of 'Connecting green network across the north and south in Seoul' plan, one of the '2020 Seoul master plan'.

• Journal of the Korean Association of Geographic Information Studies
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• v.14 no.1
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• pp.12-25
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• 2011

It is needed to preserve good effects and to prevent bad influences on local climate in urban and environmental planning. This study seeks to develop climate analysis maps to provide realistic information considering local air temperature and wind flows. Quantitative analyses are conducted by CAS for the production, transportation, and stagnation of cold air, wind flow and thermal conditions by incorporating GIS analysis on land cover and elevation and meteorological analysis from MetPhoMod - a mesoscale weather model. The CAS helps The easier analysis and assessment of urban development on local climate. It will contribute to the better life of the people in cities by providing better understanding of the local climate to the urban space planners.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.3
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• pp.1111-1114
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• 2016

Opisthorchiasis is a major problem in Thailand particularly in northeast region which also has a high incidence of cholangiocarcinomas. Since health modification is needed, this quasi-experimental study aimed to assess the effectiveness of a health education program based on self-efficacy and social support in Tha Tum district, Surin province, Thailand. A total of 70 participants were purposive selected with a history of opisthorchiasis. Participants were divided into experimental and control groups, each with 35 subjects. The experimental group received a health education program composed of: (1) knowledge improvement, lectured with multimedia, demonstration, brochure, and handbook; (2) group discussion about their health beliefs, sharing their ideas and experience; and (3) social support from village health volunteers (VHV), heads of villages (HV), friends, and members of families, and public health officer (PHO). Follow-up was by PHO/VHV/HV, with provision of certificates and flasg for household that did not eat raw fish. Data were collected by predesigned questionnaires after implementation of the program for 3 months. Comparative data was analyzed by paired simple t-test and independent t-test. The results revealed that the experimental group had mean score of knowledge higher more than before the experiment (mean difference=3.1, t=3.915, 95%CI-3.3, -1.8 p-value=0.001), and the control group (mean difference=2.5, t=4.196, 95%CI=1.4, 3.6, p-value=0.001) with statistical significance. The mean scores of practice were higher than before the experiment (mean difference=4.6, t=4.331, 95%CI-5.3, -3.1, p-value=0.001), and control group (mean difference=4.4, t=6.142, 95%CI=4.2, 7.9, p-value=0.001). The mean scores of perceived susceptibility and perceived severity of opisthorchiasis, al well as perceived benefits and perceived barriers to prevention of opisthorchiasis, were also higher than before the experiment and in the control group (p-value <0.001). In conclusion, this was a successful health education program for liver fluke avoidance. Therefore, it may useful for further behavior modification in the other epidemic areas.

• Journal of The Korean Society of Grassland and Forage Science
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• v.13 no.3
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• pp.177-183
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• 1993

This study was conducted to obtain the transformed tobacco plants with S. cerevisiae Acid phosphatase gene(PH05) using Agrobacterium tumefaciens and th confirm plant transformation and gene expression. the results obtained were summarized as follows: APase activity of Saccharomyces cereviase NA 87-11A was remarkably showed up as deep red color when assayed by Tohe and Oshima(1974). PH05 fragment, Apase gene, was obtained from pVC727G and the graphically estimated size was about 1.5kb by agarose gel electrophoresis. The sequencing results of 5'end and 3'end of PH05 using dideoxy chain termination method were coinsided with the full length nucleotide already. pBKJ I vector was constructed by isolation of PH05 fragment from pVC727-1 and pBKSI-1 digesred with Sma I and Xba I. Isolated plasmid from transformed A. tumefaciens with constructed pBKJ I when it was electrophoresed with agarose gel. The dosc of tobacco leaf was cocultivated 재소 transformed Agronacterium tumefaciens. Transformed shoots were selected on kanamtcin-containing MS-n/B medium and they were regenerated. The transgenic tobacco plants were elucidated by isolation of genomic DNA and genomic southern hybridization using ${\alpha}-^{32}P$ labelled PH05 fragments. The PH05 in transformed tobacco plants was expressed in leaf, stem and root, and its APase activity was estimated as deep red color by Tohe method.