• Title/Summary/Keyword: Phase Changing

Search Result 757, Processing Time 0.029 seconds

Quality Monitoring of Specification of Crataegi Fructus in the Korean Pharmacopoeia and Studies HPLC Standard Chromatogram (산사(山楂)의 규격 기준 모니터링 및 HPLC 표준크로마토그램 연구)

  • Kim, Kyoung Hee;Kim, Sun Mi;Lee, Young Jong;Baek, Wan Sook
    • The Korea Journal of Herbology
    • /
    • v.32 no.1
    • /
    • pp.55-62
    • /
    • 2017
  • Objectives : Crataegi Fructus has been used as traditional medicines for more digestion action, amenorrhea due to blood stasis, and hyperlipemia. The aim of this study was to compare of Crataegi Fructus in South Korea collected during three years according to the standards in monographs of the Korean Pharmacopoeia Eleventh edition (KP 11). Methods : Crataegi Fructus was carried out identification test (Qualitative reaction, Thin layer chromatography), heavy metal test, and total ash registered at KP. Add to we tested loss on dry, contents of ethanol-soluble extracts, and HPLC profiling. Results : Identification test (TLC) was on comparing with ursolic acid standard solution in $R_f$ value, all samples showed red purple spot ($R_f$ value 0.9). Ursolic acid spot in $R_f$ value 0.35 showed by changing mobile phase condition. Heavy metals showed contents for Pb, Cd, As, and Hg range of 0.0 ~ 0.5 ppm, 0.0 ~ 0.2 ppm, 0.0 ~ 0.3 ppm, and 0.0 ~ 0.1 ppm. Loss on drying was ranged from 5.5 to 11.9 %, total ash was between the range 2.7 ~ 4.0 %. Contents of ethanol-soluble extracts was ranged from 17.8 to 44.9 %. The content of chlorogenic acid was ranged from 0.0 to 0.1 % based on the chlorogenic acid standard curve. Conclusion : We have verified the current specification standard of Crataegi Fructus and standard that is not set. We hope that it will help the standardization of Crataegi Fructus.

Effects of Metal Mg on Replacement Reaction of Molten Al for Fabrication of $Al_2$O$_3$//Al Composites (Al$_2$O$_3$/Al 복합체 제조시 용융 알루미늄의 치환반응에 미치는 금속 마그네슘의 영향)

  • 정두화;배원태
    • Journal of the Korean Ceramic Society
    • /
    • v.35 no.1
    • /
    • pp.23-32
    • /
    • 1998
  • Al2O3/Al composites were produced by immersing the sintered silica preform in molten aluminum which contained magnesium as impurity. Three distinct regions existed in the penetration behavior of molten me-tal with changing the reaction temperature. These regions are denoted as low temperature regime(75$0^{\circ}C$-85$0^{\circ}C$) intermediate regime(90$0^{\circ}C$-95$0^{\circ}C$) and high temperature regime(100$0^{\circ}C$$\leq$) In the low temperature regime the penetration speed of molten aluminum increased with increasing reaction temperature whereas it decreased in the intermediate regime due to the phase transition of alumina formed by displacement reac-tion. In the high temperature regime the penetration speed of molten aluminum was the highest at 100$0^{\circ}C$ which was 3.6 mm/hr But above 105$0^{\circ}C$ molten aluminum did not penetrate into the silica preform because of the formation of a dense spinel layer at the preform surface by magnesium in molten Al.

  • PDF

A Study on Random Forest-based Estimation Model for Changing the Automatic Walking Mode of Above Knee Prosthesis (대퇴의족의 자동 보행 모드 변경을 위한 랜덤 포레스트 기반 추정 모델 개발에 관한 연구)

  • Na, Sun-Jong;Shin, Jin-Woo;Eom, Su-Hong;Lee, Eung-Hyuk
    • Journal of IKEEE
    • /
    • v.24 no.1
    • /
    • pp.9-18
    • /
    • 2020
  • The pattern recognition or fuzzy inference, which is mainly used for the development of the automatic walking mode change of the above knee prosthesis, has a disadvantage in that it is difficult to estimate with the immediate change of the walking environment. In order to solve a disadvantage, this paper developed an algorithm that automatically converts the walking mode of the next step by estimating the walking environment at a specific gait phase. Since the proposed algorithm should be implanted and operated in the microcontroller, it is developed using the random forest base in consideration of calculation amount and estimated time. The developed random forest based gait and environmental estimation model were implanted in the microcontroller and evaluated for validity.

Catalytic Activity Tests in Gas-Liquid Interface over Cu-ZnO/Al2O3 Catalyst for High Pressure Water-Gas-Shift Reaction (고압 WGS 반응을 위한 Cu-ZnO/Al2O3 촉매상에서 기-액 계면 촉매 반응 특성 연구)

  • Kim, Se-Hun;Park, No-Kuk;Lee, Tae-Jin
    • Journal of Hydrogen and New Energy
    • /
    • v.22 no.6
    • /
    • pp.905-912
    • /
    • 2011
  • In this study, the novel concept catalytic reactor was designed for water-gas shift reaction (WGS) under high pressure. The novel concept catalytic reactor was composed of an autoclave, the catalyst, and liquid water. Cu-ZnO/$Al_2O_3$ as the low temperature shift catalyst was used for WGS reaction. WGS in the novel concept catalytic reactor was carried out at the ranges of 150~$250^{\circ}C$ and 30~50 atm. The liquid water was filled at the bottom of the autoclave catalytic reactor and the catalyst of pellet type was located at the gas-liquid water interface. It was concluded that WGS reaction occurred over the surface of catalysts partially wetted with liquid water. The conversion of CO for WGS was also controlled with changing content of Cu and ZnO used as the catalytic active components. Meanwhile, the catalyst of honey comb type coated with Cu-ZnO/$Al_2O_3$ was used in order to increase the contact area between wet-surface of catalyst and the reactants of gas phase. It was confirmed from these experiments that $H_2$/CO ratio of the simulated coal gas increased from 0.5 to 0.8 by WGS at gas-liquid water interface over the wet surface of honey comb type catalyst at $250^{\circ}C$ and 50 atm.

Concentration of Sodium Chloride, Sodium Acetate and Sodium Citrate Solutions by using Polyamide Reverse Osmosis Membrane (폴리아미드 역삼투막을 이용한 염화나트륨, 아세트산나트륨, 구연산나트륨 용액의 농축)

  • Lee, Heungil;Kim, In Ho
    • Korean Chemical Engineering Research
    • /
    • v.56 no.5
    • /
    • pp.679-686
    • /
    • 2018
  • Reverse osmosis (RO) concentration of sodium chloride, sodium acetate, and sodium citrate solutions has been performed by polyamide RO membrane. Concentration polarization phenomena was also studied by changing pressure, solute kinds, and initial solution concentration. Pressure effect on permeation flux was that the increase of flux was accompanied by the increase of pressure. Flux increase was observed by the decrease of initial solution concentration. Surface concentration on the RO membrane increases and so flux declines due to the concentration polarization. In the later phase of concentration, concentration polarization effect was decreased by the back diffusion of solute from the polariztion layer. In case of sodium citrate, its large ion size and charge density resulted in the discrepancy between theory and experimental data of concentration polarization. It may be due to electric repulsion on the membrane surface.

On the Analysis of DS/CDMA Multi-hop Packet Radio Network with Auxiliary Markov Transient Matrix. (보조 Markov 천이행렬을 이용한 DS/CDMA 다중도약 패킷무선망 분석)

  • 이정재
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.19 no.5
    • /
    • pp.805-814
    • /
    • 1994
  • In this paper, we introduce a new method which is available for analyzing the throughput of the packet radio network by using the auxiliary Markov transient matrix with a failure state and a success state. And we consider the effect of symbol error for the network state(X, R) consisted of the number of transmitting PRU X and receiving PRU R. We examine the packet radio network of a continuous time Markov chain model, and the direct sequence binary phase shift keying CDMA radio channel with hard decision Viterbi decoding and bit-by-bit changing spreading code. For the unslotted distributed multi-hop packet radio network, we assume that the packet error due to a symbol error of radio channel has Poisson process, and the time period of an error occurrence is exponentially distributed. Through the throughputs which are found as a function of radio channel parameters, such as the received signal to noise ratio and chips of spreading code per symbol, and of network parameters, such as the number of PRU and offered traffic rate, it is shown that this composite analysis enables us to combine the Markovian packet radio network model with a coded DS/BPSK CDMA radio channel.

  • PDF

A Branch-Line Hybrid Using Triangle-Patch Type Artificial Transmission Line (삼각 패치형 인공 전송 선로를 이용한 브랜치 라인 하이브리드)

  • Oh, Song-Yi;Hwang, Hee-Yong
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
    • /
    • v.23 no.7
    • /
    • pp.768-773
    • /
    • 2012
  • A branch-line hybrid using microstrip artificial transmission lines(ATLs) with slotted-triangular patches is proposed. The proposed artificial transmission line is compact in structure as well as easy to adjust the characteristic impedance and electrical length of equivalent transmission line by changing the slot's parameters; hence, it is useful for miniaturizing conventional transmission lines. The designed branch-line hybrid, because of the use of the right angled isosceles triangular shaped artificial transmission lines as building blocks, has no useless empty space, and hence optimally miniaturized. A fabricated 3 dB branch-line hybrid shows the coupling variation of ${\pm}0.5$ dB and the phase difference between two output ports of $91^{\circ}{\pm}4^{\circ}$ within 15 % bandwidth at 2.45 GHz center frequency. The size of proposed branch-line hybrid is only 38% of the conventional branch-line hybrid.

Effect of Crystal Form on Bioavailability (결정형이 생체이용률에 미치는 영향)

  • Sohn, Young-Taek
    • Journal of Pharmaceutical Investigation
    • /
    • v.34 no.6
    • /
    • pp.443-452
    • /
    • 2004
  • Habit is the description of the outer appearance of a crystal. If the environment of a growing crystal affects its external shape without changing its internal structure, a different habit results. Crystal habit and the internal structure of a drug can affect bulk and physicochemical properties, which range from flowability to chemical stability. A polymorph is a solid crystalline phase of a given compound resulting from the possibility of at least two different arrangements of the molecules of that compound in the solid state. Chemical stability and solubility changes due to polymorphism can have an impact on a drug's bioavailability and its development program. During crystallization from a solution, crystals separating may consist of a pure component or be a molecular compound. Solvates are molecular complexes that have incorporated the crystallizing solvent molecule in their lattice. When the solvent incorporated in the solvate is water, it is called a hydrate. To distinguish solvates from polymorphs, which are not molecular compounds, the term pseudopolymorph is used. Identification of possible hydrate compounds is important since their aqueous solubilities can be significantly less than their anhydrous forms. Conversion of an anhydrous compound to a hydrate within the dosage form may reduce the dissolution rate and extent of drug absorption. An amorphous solid may be treated as a supercooled liquid in which the arrangement of molecules is random. Amorphous solids lack the three-dimensional long-range order found in crystalline solids. Since amorphous forms are usually of higher thermodynamic energy than corresponding crystalline forms, solubilities as well as dissolution rates are generally greater. A study on crystal form includes characterization of (l)crystal habit, (2)polymorphism, (3)pseudopolymorphism, (4)amorphous solid.

Development of Application to Deal with Large Data Using Hadoop for 3D Printer (하둡을 이용한 3D 프린터용 대용량 데이터 처리 응용 개발)

  • Lee, Kang Eun;Kim, Sungsuk
    • KIPS Transactions on Software and Data Engineering
    • /
    • v.9 no.1
    • /
    • pp.11-16
    • /
    • 2020
  • 3D printing is one of the emerging technologies and getting a lot of attention. To do 3D printing, 3D model is first generated, and then converted to G-code which is 3D printer's operations. Facet, which is a small triangle, represents a small surface of 3D model. Depending on the height or precision of the 3D model, the number of facets becomes very large and so the conversion time from 3D model to G-code takes longer. Apach Hadoop is a software framework to support distributed processing for large data set and its application range gets widening. In this paper, Hadoop is used to do the conversion works time-efficient way. 2-phase distributed algorithm is developed first. In the algorithm, all facets are sorted according to its lowest Z-value, divided into N parts, and converted on several nodes independently. The algorithm is implemented in four steps; preprocessing - Map - Shuffling - Reduce of Hadoop. Finally, to show the performance evaluation, Hadoop systems are set up and converts testing 3D model while changing the height or precision.

Effect of Hydrophilic- and Hydrophobic-Media on the Fermentative Hydrogen Production in Trickling Bed Biofilter (생물학적 수소생산을 위한 Trickling Bed Biofilter에서의 친수성과 소수성 담체의 영향)

  • Jeon, Byung-Seung;Lee, Sun-Mi;Kim, Yong-Hwan;Chae, Hee-Jeong;Sang, Byoung-In
    • 한국신재생에너지학회:학술대회논문집
    • /
    • 2006.06a
    • /
    • pp.465-469
    • /
    • 2006
  • Two mesophilic trickling bed bioreactors filled with two different types of media, hydrophilic- and hydrophobic-cubes, were designed and tested for hydrogen production via anaerobic fermentation of sucrose. Each reactor consisted of a column packed with polymeric cubes and inoculated with heat-treated sludge obtained from anaerobic digestion tank. A defined medium containing sucrose was fed with changing flow rate into the capped reactor, hydraulic retention time and recycle rate. Hydrogen concentrations in gas-phase were constant, averaging 40% for all conditions tested. Hydrogen production rates increased up to $10.5 L{\cdot};h^{-1}{\cdot}L^{-1}$ of reactor when influent sucrose concentrations and recycle rates were varied. Hydrophobic media provided higher value of hydrogen production rate than hydrophilic media at the same operation conditions. No methane was detected when the reactor was under a normal operation. The major fermentation by-products in the liquid effluent of the both trickling biofilters were acetate and butyrate. The reactor filled with hydrophilic media became clogged with biomass and bio gas, requiring manual cleaning of the system, while no clogging occurred in the reactor with hydrophobic media. In order to make long-term operation of the reactor filled with hydrophilic media feasible, biofilm accumulation inside the media in the reactor with hydrophilic media and biogas produced from the reactor will need to be controlled through some process such as periodical backwashing or gas-purging. These tests using trickling bed biofilter with hydrophobic media demonstrate the feasibility of the process to produce hydrogen gas in a trickle-bed type of reactor. A likely application of this reactor technology could be hydrogen gas recovery from pre-treatment of high carbohydrate-containing wastewaters.

  • PDF