• Title/Summary/Keyword: Pharmaceutical Industry

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Comparison of Fentanyl-Based Rapid Onset Opioids for the Relief of Breakthrough Cancer Pain: Drug Price Based on Effect Size

  • Seongchul Kim;Hayoun Jung;Jina Park;Jinsol Baek;Yeojin Yun;Junghwa Hong;Eunyoung Kim
    • Korean Journal of Clinical Pharmacy
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    • v.33 no.1
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    • pp.43-50
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    • 2023
  • Background and Objective: With the advancement of cancer treatments and increased life expectancy, managing breakthrough cancer pain (BTcP) is essential to improve the quality of life for cancer patients. This study aimed to compare the major rapid onset opioids in Korea based on their characteristics and costs to determine the best option for each patient. Methods: Based on sales information from IQVIA-MIDAS, sublingual fentanyl tablet (SLF), fentanyl buccal tablet (FBT), and oral transmucosal fentanyl citrate (OTFC) were selected as the top three drugs for the treatment of BTcP in Korea, considering them the most comparable drugs. The cost and cost-pain relief ratio of the drugs for short-term (1 month) and long-term (1 year) treatment were compared and the ease of administration based on various factors, including pharmacokinetics, onset of action, and administration procedures were evaluated. Results: SLF was evaluated as the best overall in terms of rapid onset of action, ease of administration, and drug cost and also had the highest market share. SLF had the lowest cost pain relief ratio for both the initial and supplemental treatment for the 1-month pain intensity difference 15 (PID15) ratio. However, for the 1-month PID30 ratio, SLF was not superior to OTFC or FBT. The longer the breakthrough cancer pain duration, the more cost-effective the other rapid onset opioids. Conclusion: The rapid onset opioids that fit the patient's breakthrough cancer pain pattern have the best cost-effectiveness.

Cold Chain Management in Pharmaceutical Industry: Logistics Perspective

  • Yoon, Yuri
    • Journal of Distribution Science
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    • v.12 no.5
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    • pp.33-40
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    • 2014
  • Purpose - This paper aims to review cold chain management, especially in the pharmaceutical industry, to explore the cold chain process of delivering temperature-sensitive pharmaceutical products, and to identify areas for further development. Research design, data, and methodology - The paper, based on literature review and corporate analysis, reviews the development and status of the cold supply chain system, including its important role in the pharmaceutical industry. Results - Logistics in this field requires more stages than are typically needed. Due to the unique characteristics of the market, few companies can provide the services; currently, only few global companies with large networks and high technologies can afford to do so. Expanding pharmaceutical markets to meet global demand will require cold chain development, especially in "pharmerging" markets. Conclusions - Cold chain is a highly sensitive market in terms of products being carried within the chain that itself is a complex system. However, at the same time, it is a niche market with new opportunities. Hence, a sound cold chain infrastructure is needed to satisfy companies, governments, and customers for both commercial and public reasons.

A Study on Integrated Physical Distribution of the Pharmaceutical Industry in Korea (한국제약산업의 통합물류에 관한 연구)

  • Kwon, Oh-cheul;Youn, Myoung-kil;Namkung, Suk
    • Journal of Distribution Science
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    • v.5 no.2
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    • pp.17-34
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    • 2007
  • The Korean pharmaceutical industry has many pharmaceutical companies and business acquaintances, small quantity batch production and a lot of competition products having same ingredient. Under such a situation, an integrated distribution is said to be proper to lower distribution costs and deliver effectively: However, each business has different delivery conditions, timely delivery of small quantity batch order and other particular services, etc to have problems of competition of turnover increase. The study suggests measures below to lower distribution costs and to elevate sales business efficiency. First, Joint marketing of pharmaceuticals between pharmaceutical companies. Second, Joint delivery of three or less companies having similar business scales. Third, An agreement with wholesale distributors of unified distribution of pharmaceuticals being sold much. Fourthly, Wholesale distributors' pharmaceuticals distribution services. Fifthly, Cooperation of business acquaintance. In summary, the Korean pharmaceutical industry needs an integrated distribution system. Considering characteristics of the industry, however, the small pharmaceutical companies are thought to be difficult to accept the integrated distribution because complete integrated distribution may reduce sales.

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System Dynamics Modeling for FDA Regulation Effect of Pharmaceutical Industry (제약산업에서 FDA규제 영향에 관한 시스템 다이내믹스 모델링: FDA규제가 R&D비용에 미치는 영향을 중심으로)

  • Ko, Seong-Pil;Choi, Jeong-Hwan;Nam, Dong-Wok;Lee, Jeong-Dong
    • Korean System Dynamics Review
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    • v.13 no.4
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    • pp.57-80
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    • 2012
  • This research studies effect of FDA regulations in pharmaceutical industry on new drug development. System dynamics is implemented to demonstrate dynamic relationship between FDA regulations and R&D costs, firm's profits, sales. This research is focused on clinical trials of new medical entity process 50~60% portion of total development cost. Simulation results say that firm's profit is more sensitive to increasing the regulation than alleviating the regulation and effect of regulation policy make different result depending on the intensity of regulation and policy direction. Our simulation model provides the instrumental means for the policy makers and strategic decision in pharmaceutical industry.

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Transforming Inter-Organizational Information Systems into Electronic Commerce Marketplaces: Development of B2B Electronic Commerce in China's Pharmaceutical Industry

  • Li Mingzhi;Tu Yulin;Wang Xiaochen;Reimers Kai
    • Management Science and Financial Engineering
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    • v.11 no.3
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    • pp.61-78
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    • 2005
  • The aim of this paper is to identify the barriers to the B2B e-commerce development in China's pharmaceutical industry and to devise an effective strategy for its future development. Built on a detailed investigation of the market structure and recent development of electronic commerce in China's pharmaceutical industry, this paper proposes that the key issue in the development of effective B2B e-commerce business models is the successful transformation of the inter- organizational information systems into electronic marketplaces. In order to ensure the success of such electronic marketplaces, a government driven approach will be needed. In the process, designing an incentive compatible mechanism of coordinating the interest of all the market players will be the prerequisite.

Competitiveness in Exports of Pharmaceuticals to Developed Countries: A Comparative Policy Analysis on South Korea and India (선진국으로의 의약품 수출 경쟁력: 한국과 인도를 대상으로 한 정책비교분석 연구)

  • Yun, Su-Jin;Cho, Eun
    • YAKHAK HOEJI
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    • v.56 no.2
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    • pp.116-125
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    • 2012
  • Local pharmaceutical companies in Korea, which have grown focusing on domestic markets, have recently faced difficulties such as market saturation, price control policies and market-opening pressures by FTA. It seems to be an urgent issue for them to export pharmaceuticals to developed countries comprising the greater part of the global pharmaceutical market. Hence, this research was conducted to investigate and benchmark the strategies employed by India industry for the successful access to the global pharmaceutical markets. Drug policies as well as their influences on pharmaceutical market changes between India and Korea for the last 40 years have been searched and the differences have been comparatively analyzed. The pharmaceutical industry of India has the following strengths: low costs; experienced labor pool; excellent reverse-engineering skills; powerful IT; marketing capability; and established distribution network. After 2000, consolidations, M&A and alliances with domestic and multinational companies have been sharply increased in the industry of India. Indian companies unfolding both competition and cooperation with multinational corporations currently move up the value-added chain, and this enthusiastic strategy should be learned by local pharmaceutical companies.

Effects of Pharmaceutical Salesperson's Perception on Core Capabilities -Focusing on the Company Culture and Reputation of Pharmaceutical Companies-

  • Byun, Kwangmin;Ryu, Ki-hwan
    • International Journal of Advanced Culture Technology
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    • v.9 no.3
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    • pp.160-166
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    • 2021
  • Due to rapid environmental-change pharmaceutical industry, sales strategy for sales survival of pharmaceutical company is necessary. In accordance with the rapid development of medicine and advancement of efforts to secure the market, competition among pharmaceutical companies make an effort to achieve their goals. However, due to various negative influence of inside and outside, this field is getting a difficult occupation. Even when securing and training new employees with quite a bit of expense and time, the rate of surviving employees over 1 year is decreasing. For this, the researcher suggested major research result through actual investigation by utilizing survey technique, and a plan to enhance pharmaceutical company salespersons' core competence and raise sales achievement. As the research result, company culture strongly influences salespersons' sales ability. We defined the formation of organizational culture, which influences communication culture where smooth communication is made in the company, also, definite and exact evaluation in promoting work, and trust formation between upper and lower organization, is important, which should be reflected in the company field.

An Analysis on the Effect of the Government R&D Subsidies on the Private R&D Investments : in the Case of the Pharmaceutical Industry (정부 R&D 지원의 기업 R&D 투자에 대한 효과 분석 -제약산업을 중심으로-)

  • SaKong, Jin;Shin, You-Won
    • Health Policy and Management
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    • v.20 no.1
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    • pp.183-203
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    • 2010
  • The purpose of this study is to analyze the effect of the R&D subsidies by the government on the private firms' R&D investments in the Korean pharmaceutical industry, which are supposed to have positive effects on their economic performance. We also estimate the relationship between the private firms' R&D investments and firms' economic outcome. Empirical analysis is done by Error Component 2 Stage Least Squares(EC2SLS) estimation using 43 pharmaceutical firms' 8 years' panel data. The elasticity of the government R&D subsidies on the private R&D investments is 0.021%, which we cannot say 'efficient'. Also R&D investments have positive effects on the economic outcome of the pharmaceutical firms, as we expected. We propose several suggestions in the conclusion for the efficient way of government R&D subsidies to induce more private R&D investments.

Collaborative Communication, Information Sharing and Supply Chain Performance

  • LEE, Changjoon;KIM, Soohyo
    • The Journal of Industrial Distribution & Business
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    • v.12 no.5
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    • pp.27-36
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    • 2021
  • Purpose: This study empirically investigates the effect of collaborative communication and information sharing on the supply chain performance of South Korean pharmaceutical companies. Specifically, it understands the importance collaborative communication and suggests a method for investigating communication in academic research on the pharmaceutical industry. Investigating this sector is crucial because the importance of the pharmaceutical industry is increasing globally against the background of the Covid-19 pandemic. Research design, data, and methodology: A questionnaire was administered to employees of South Korean pharmaceutical companies and 244 valid responses were used for the statistical analysis. Additionally, structural equation modeling was used to measure the relationships between the observed and latent variables. Results: Collaborative communication has a positive effect on information sharing. However, information sharing, unlike collaborative communication, does not exhibit a significant positive relationship with supply chain performance. These results indicate that it is important to communicate effectively in the supply chain rather than strive for the right type of information sharing. Conclusions: Consumers and retailers within the supply chain should continue to strive for candid communication. This study is meaningful, as it empirically tests the relationships between collaborative communication, information sharing, and supply chain performance in the South Korean pharmaceutical industry.

General Public Knowledge Regarding Topical Corticosteroids: A Nationwide Survey in South Korea

  • Seo, Heenam;Song, Seoung Yeon;Kim, Dahye;Park, Ji Hwan;Shin, Yoonho;Lee, Kang Hyuk;Choi, Soo An;Lee, Ju-Yeun;Kim, Do Young;Shin, Wan Gyoon;Kim, Eunyoung
    • Korean Journal of Clinical Pharmacy
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    • v.32 no.2
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    • pp.84-92
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    • 2022
  • Background: Topical corticosteroids (TCs) are available both as over-the-counter drugs and prescription medicines at pharmacies. Although they are generally safe drugs, inappropriate and excessive use could result in potential side effects. Thus, it is important to have appropriate knowledge regarding the use of TCs. We performed a cross-sectional survey to assess public knowledge and the potential misuse or overuse of TCs. Methods: A cross-sectional and nationwide online survey was conducted among participants who were aware of TCs. The survey items included sources of information, indications, potential side effects, and methods of application of TCs. A comparative analysis was conducted between those with (TC users) and without (TC non-users) an experience of using TCs. Results: Among 3,000 participants, 74.4% were TC users. The mass media was the most common information source of TCs, and only one-third of the surveyed people relied on pharmacists or doctors for information. Regarding indications and application methods, incorrect answer rate was high in some items, but respondents showed adequate knowledge. However, awareness of the safety of TCs was low. Overall, the TC users showed a higher knowledge of TCs than TC non-users. Conclusions: Public knowledge of the use of TCs appears to be appropriate. However, we found potential misuse or overuse of some items and a lack of awareness of the side effects concerning TCs. Thus, healthcare professionals' significant role is required.