• 대한기계학회논문집
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• 제18권10호
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• pp.2751-2761
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• 1994

A numerical investigation on the three-dimensional laminar natural convection heat transfer in the periodically fully developed PCB channel has been performed. When heat generating blocks mounted on the adiabatic wall make a channel with their facing shrouding wall, the flow inside the channel becomes periodically fully developed. A single module in the periodically fully developed region is chosen for computational domain in order to save computer storage and computational time. The periodic boundary condition is applied in the anlaysis. The effects of the parameters such as the Rayleigh number, the number of the modules, and the height of channel are examined to obtain the optimum condition for the enhancement of the cooling effectiveness. The result shows that the cooling effect is improved with increasing Rayleigh number and channel height, and decreasing the number of the module. The result also indicates that increasing the height of the channel and number of the module is recommended for a limited space.

• 대한기계학회논문집B
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• 제22권1호
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• pp.122-130
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• 1998

The present work analyzes the pressure drop and heat transfer characteristics of the plate heat exchanger with staggered dimples. The flow is assumed to be constant property, three dimensional and laminar. A thermal boundary condition is uniform wall temperature and it is assumed that the flow is periodically fully developed. Elliptic grid generation is used for proper modelling of the internal tube geometry with dimples. Computations have been carried out for a variety of geometric parameters, Reynolds number, and Prandtl number. The friction factor ratio and the ratio of a module average Nusselt number are presented for the cases considered in this study. It is found that the distance between dimples has a substantial effect on the pressure drop and heat transfer.

• 설비공학논문집
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• 제10권1호
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• pp.129-136
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• 1998

Pressure drop and heat transfer characteristics of a periodically fully developed flow in the flat channel with protrusions are investigated. The effects of shape and location of protrusion on the pressure drop and heat transfer are numerically analyzed in the present study. Taguchi method is used to optimize these parameters. It is found that the ratio of the height of protrusion to channel height shows larger influence on the pressure drop and heat transfer than the ratio of the length of protrusion to module length. As the height of protrusion increases, pressure drop and heat transfer increase, but if the height of protrusion exceeds 2/3 of the channel height, there is a substantial pressure drop. The results also show that the optimal length and height of protrusion are half of the module length and half of the channel height, respectively.

• 대한기계학회논문집B
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• 제23권5호
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• pp.678-686
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• 1999

The purpose of this work is to Investigate the pressure drop and the heat transfer characteristics in the channel of plate heat exchanger with crossed-discrete ribs. The flow is assumed to be three-dimensional, laminar and periodically fully developed. Computations have been carried out for angles of attack from $0^{\circ}$ to $90^{\circ}$ and ratios of rib height from 0.15 to 0.46 for various values of Reynolds and Prandtl numbers. The heat transfer was improved by inclined ribs generating helical vortices and secondary flows. The results show that the pressure drop has a maximum value at $70^{\circ}$ and the heat transfer has a maximum value at $45^{\circ}$. As the rib height increases, the pressure drop and the heat transfer increase quadratically, and the increasing rate of pressure drop is higher than that of the heat transfer. As Reynolds number increases, the pressure drop increases in proportion to the square of Reynolds number and the heat transfer increases linearly.

• 대한기계학회논문집
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• 제10권1호
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• pp.138-149
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• 1986

본 연구에서는 위의 방법을 수정 발전시켜 완전확립된 난류유동과 열전달장을 해석하였다. 본 연구에서 해석한 유동장은 Fig.3과 같이 내관 외면에 직사각형 인공 조도를 갖고 외관은 매끈한 이중동심원관내의 유동이며, 해의 정확성을 높이기 위하여 Leschziner & Rodi의 유선곡률모델을 수정보완하여 사용하였으며 수치해석의 오류확산 을 감소시키기 위하여 QUICK 해법을 사용하였다.

• 설비공학논문집
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• 제16권4호
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• pp.368-373
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• 2004

A flow field in a passage with periodically converging-diverging cross-section is investigated experimentally by PIV measurement. A tube with a sinusoidally wavy cross section is one of several devices employed for enhancing the heat and mass transfer efficiency due to turbulence promotion and unsteady vortical motion. While the numerical flow visualization results have been limited to the fully developed cases, existing experimental results of this flow were simple qualitative ones by smoke or dye streak test. Therefore, the main purpose of this study is to produce quantitative flow data for fully developed and transient flow regime by the Correlation Based Correction PIV (CBC PIV) and to conjecture the analogy between flow characteristics and heat transfer enhancement with low pumping power. Another purpose of this paper is to examine the onset position of the transition and the global mixing, which results in transfer enhancement. At Re=2000, evidences of the global mixing are captured at 2.5 wavy module through the variation of RMS values and instantaneous velocity plot.

• 대한기계학회논문집
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• 제18권9호
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• pp.2443-2453
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• 1994

The structure of turbulence of fully developed flow through four concentric annuli with the rough outer wall was investigated experimentally for a Reynolds number range Re=15, 000-93, 000. Turbulence intensities were measured in three(u, v, w) directions, and turbulence shear stresses in annuli of radius=0.13, 0.26, 0.4 and 0.56, respectively. Due to the square roughness element attached periodically along the axial direction, the radial velocity fluctuations show similar distribution regardless of the different .alpha.cases. However, the axial and circumferential velocity fluctuation profiles demonstrate the longitudinal turbulence structures are strongly influenced by the .alpha. values. The turbulent eddy viscosity deduced form mean velocity distributions and the measured Reynolds shear stresses are also presented and discussed.

• 대한설비공학회지:설비저널
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• 제17권4호
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• pp.473-488
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• 1988

This paper is concerned with the prediction of two dimensional turbulent flows in the parallel plate with the repeated cylindrical blockages. The purpose of this paper is to find the effect of the eccentricity and the pitch of the repeated cylindrical blockages on the flow field, heat transfer coefficients and friction factors. A special technique is developed for the solution of the fully developed turbulent recirculating flow, in which the flow field varies periodically. A non-othogonal coordinate transformation is employed to solve the momentum and the energy equations. The results show that the pitch ratio or the eccentricity of the repeated blockages become smaller, or the Reynolds number of the flow larger, friction factors and heat transfer coefficients increase.

• 대한기계학회논문집
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• 제9권2호
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• pp.202-212
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• 1985

본 논문에서는 이러한 연구의 첫단계로 Gosman과 Ideriah가 다룬 TEACH-2E전 산프로그램을 모체로 하여 본 논문의 문제에 적합하도록 수정하여 사용하였다. 그러 나 기본적인 k-.epsilon.난류모델은 수정하지 않았다. 한편, 본 논문에서는 열선풍속계를 이용하여 평균 속도분포 및 난류특성을 계측하고 계산결과와 비교하였다. 이를 통하 여 표준형 k-.epsilon.모델을 이용한 TEACH-2E코드의 특성을 파악하고 이를 위한 실험 데이터 를 확보하는데 중점을 두었다.

• Biomolecules & Therapeutics
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• 제22권4호
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• pp.355-362
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• 2014

We have developed a fully automated high throughput drug screening (HTDS) system based on the microfluidic cell culture array to perform combinational chemotherapy. This system has 64 individually addressable cell culture chambers where the sequential combinatorial concentrations of two different drugs can be generated by two microfluidic diffusive mixers. Each diffusive mixer has two integrated micropumps connected to the media and the drug reservoirs respectively for generating the desired combination without the need for any extra equipment to perfuse the solution such as syringe pumps. The cell array is periodically exposed to the drug combination with the programmed LabVIEW system during a couple of days without extra handling after seeding the cells into the microfluidic device and also, this device does not require the continuous generation of solutions compared to the previous systems. Therefore, the total amount of drug being consumed per experiment is less than a few hundred micro liters in each reservoir. The utility of this system is demonstrated through investigating the viability of the prostate cancer PC3 cell line with the combinational treatments of curcumin and tumor necrosis factor-alpha related apoptosis inducing ligand (TRAIL). Our results suggest that the system can be used for screening and optimizing drug combination with a small amount of reagent for combinatorial chemotherapy against cancer cells.