• Journal of Chest Surgery
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• 제2권2호
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• pp.168-186
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• 1969

Two groups of esophagus graft were done in canine esophagus in 34 adult mongrel dogs. For the first group segmental replacement graft was done with fresh autologous pericardium tube, and for the second, patch graft was done utilizing fresh autologous pericardium, fresh homologous pericardium,and dacron piece. All eight dogs in the first segmental replacement graft group died 2 to 5 days after operation with severe empyema caused by anastomosis disruption. Among 26 patch graft dogs 2 died during operation and 7 died 13 to 18 days after operation. For the 17 long-term patch grafted survivors esophagography and postoperative weight check were done. Postoperative stool was collected and examined for dacron patch excretion. One, two, three, and four months postoperative long-term survivors were sacrificed to obtain specimens in each group respectively and the following observations were made. I. Survival; Autologous pericardium patch group showed no mortality but in homologous pericardium and dacron patch group only two thirds were long-term survivors. II. Postoperative swallowing; There was no case which demonstrated postoperative dysphagia. About half of the cases showed postoperative weight increase and in only 3 cases weight decrease followed operation. III. Dacron patch was excreted in the stool 8 to 23 days after operation. Animals which excreted dacron patch up to 9 days after operation all died of empyema due to anastomosis disruption. IV. Postoperative esophagogram; All esophagograms in each group showed no leakage of barium, no passage disturbances and no remarkable stenotic signs. V. Morphological findings; [A] Macroscopical findings; In one month group specimens of each group dense adhesion with surrounding structures was noted and luminal surface was smooth with contraction of the patched area. In two month groups anastomosis sutures were still exposed but patched area showed lesser abnormality. In three to four months groups sutures were covered completely and patched area showed only very slight signs of contraction. [B] Microscopic findings; In one month group luminal surface of the replaced tissue [transplanted tissue] showed almost complete epithelial covering that is composed of several layers of squamous cells with no evidence of keratinization. Basement membrane was also well distinct throughout. Slight to minimal inflammatory cells comprising of large mononuclears, lymphocytes and plasma cells were observed in the subepithelial fibrous stroma consisted entirely of loose fibrous tissue containing many newly formed capillaries and fibroblastic proliferation. Scattered suture granulomas were found, few of which became acutely inflamed. In two months group repairing process progressed with lesser degree of inflammatory cell infiltration and young capillary proliferation. Fibrous tissue was more matured showing even focal collagenization. Suture granuloma persisted but with lesser reactive changes. Epithelial covering was that of a mature non-keratinizing stratified squamous epithelium. In three and four months groups the replaced area showed essentially similar histological findings. However, subepithelial stroma still consisted entirely of connective tissue without evidence of smooth muscle regeneration. In this group, inflammatory cell infiltration was minimal or negligible. Among these patch materials autologous pericardium group showed the most satisfactory repairing process. The above mentioned results may signify the feasibility of autogenous pericardium patch graft in clinical esophageal surgery.

• 대한추나의학회지
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• 제4권1호
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• pp.167-171
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• 2003

Objectives: The Applied Kinesiology(A.K) doctors diagnose and treat a patient by using muscles related to 12 main meridian. The purpose of study is to make It clear what the Correlationship in SuSamUm-Kyung of 12 Joung-Kyung with Muscles in A.K is. Method: In the Lung meridian and the Heart meridian, the Sidong.Sosang-disease and the related muscles are used. In the Pericardium meridian Correlationship in the Kidney with the lower limbs and the Pericardium with the Kidney is used. Results & Conclusion: Summarized as follows 1. The Lung meridian is related to the triceps and the levator scapulae in th Sidong.Sosang-disease and the serratus anterior in the symptoms of the muscles' stiffness. 2. The Heart meridian is related to the subscapularis in The Applied Kinesiology(A.K) the referred pain of the subscapularis and KukCheon-hole of The Heart meridian. 3. The Pericardium meridian is related to the correlated muscles in the correlationship the Kidney with the lower limbs and the Pericardium with the Kidney.

• Journal of Chest Surgery
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• 제10권1호
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• pp.7-17
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• 1977

The increasing frequency of post-tracheostomy stenosis parallels the increase in the incidence of tracheostomy. The development of stenosis of trachea following the operation of tracheal tumor or tracheostomy is a very serious complication. The continuing need for an adequate tracheal substitute has not been answered, despite the necessities of excision and reconstruction of the trachea to keep for effective ventilation. Experimental tracheal reconstuction, with a prosthesis of heavy Marlex mesh and pericardium, _ vas performed in twelve dogs. Five to six tracheal ring circumferential defects were created and were bridged with heavy Marlex mesh fashioned into a tube of suitable diameter. Group A: A prepared cylinder of Marlex mesh was anastomosed outside the cut ends of the trachea. Group B: The external surface of the prepared cylinder of Marlex mesh was completely covered with suitably sized patch of pericardium and overlapped all margin of the Marlex mesh by 2 to 3 mm in each direction. Group C: The internal surface of the prepared cylinder of Marlex mesh was covered with suitably sized patch of pericardium and overlapped all margin of the Marlex mesh by 2 to 3 mm in each direction. The results of this exepriment were as follow: 1. In group A and B, the graft was well bridged with new granulation and fibrous tissue, and the lumen of trachea kept good patency for effective ventilation.. The interstices of Marlex became uniformly infiltrated with young well vasculated connective tissue. Epithelization has not yet occurred at 4 weeks in each group, but there were evidences of new growing mucosa at grafted site in 6 weeks. The remainder of the prosthesis was completely covered with glistening epithelium and the underlying fibrous tissue became more matured with little inflammation. These findings were more striking in group B than group A. 2. In group C, the covered pericardium was necrotized with stenosis of the lumen of grafted site due to poor blood supply.

• 대한영상의학회지
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• 제82권3호
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• pp.749-755
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• 2021

선천성 심막결손은 대부분의 환자가 무증상을 보이는 드문 질환으로 전체 혹은 부분 심막결손으로 나타난다. 본 논문에서는 기흉 증상으로 인해 우연히 좌측 선천성 심막결손을 진단받은 19세 남성 환자를 보고하고자 한다. 일반 흉부 X선 사진 및 컴퓨터단층촬영에서 외상의 흔적이 없는 무기폐, 상행대동맥의 우측에 비정상적으로 위치한 공기, 좌측 흉부로 전위된 심장, 그리고 납작한 흉곽이 보였다. 뒤이은 흉강경검사에서 좌측 심막결손과 왼쪽 흉강으로의 심장 전위가 확인되었다. 이는 영상의학적 소견과 수술적 소견이 잘 일치하는 자발성 기흉이 동반된 선천성 심막결손에 관한 보고이다.

• Journal of Chest Surgery
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• 제24권9호
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• pp.837-842
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• 1991

Calcification is a major problem in glutaraldehyde-preserved bioprosthetic valves. We have used bovine pericardium processed in a solution containing 0.625% glutaraldehyde, 0.05M HEPES buffer and 0.26% magnesium chloride in saline. And, we also treated the glutaraldehyde-preserved bovine pericardium with a surfactant, Triton X - 100 to reduce calcification. To evaluate the degree of calcification. 4 kinds of pericardial xenografts, group I [Xenomedica, equine pericardial xenografts], group II [0.625% glutaraldehyde-preserved bovine pericardiums], group III [0.5% Triton X - 100 treated bovine pericardiums], and group IV [1.2% Triton X - 100 treated bovine pericardiums] were implanted in subcutaneous layer of growing rabbits, and they were explanted about 3 months later. The mean calcium contents[%/mg of dry tissue] of 0.5% and 1.2% Triton X - 100 treated bovine pericardiums [80.0$\pm$27.1%: 78.6$\pm$47.0% respectively] were lower than those of glutaraldehyde-preserved bovine pericardiums[126.2$\pm$29.8] [p=0.05]. Thus, under the conditions of subcutaneous implantation in rabbits, Triton X - 100 was efficient in calcification mitigation.

• 대한한의학원전학회지
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• 제23권2호
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• pp.119-124
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• 2010

Literally Simdokmusu(心獨無腧) means only Heart meridian doesn't have acupuncture points. But in Oriental medical classics such as "Hwangjenaegyeong(黃帝內經)", Heart meridian has been explained it has acupuncture points. Then, what does it mean? First, we take a careful look how it is different between Oriental medical classics describing meridian pathway. Next, we focus on Pericardium meridian(PC) because Heart and Pericardium meridian have several similarities in many ways. With those methods, we try to reveal the meaning of simdokmusu(心獨無腧) as a conclusion.

• Journal of Chest Surgery
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• 제37권5호
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• pp.452-455
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• 2004

호흡곤란을 주소로 46세 여자 환자가 내원하여, 윤상 심막 석회화에 의한 좌심실 이완장애와 우심실 유출로 협착을 진단받았다. 수술장 소견상 윤상으로 심하게 석회화 띠가 폐동맥 기시부와 좌심실 중간 부위를 지나고 있었으며 이외의 심막은 경도의 섬유화만이 관찰되었다. 수술은 체외순환하에 시행하였고 환자는 특별한 합병증 없이 회복되었으며 심막 석회화의 원인은 찾을 수 없었다.

• Journal of Chest Surgery
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• 제35권6호
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• pp.487-490
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• 2002

65세 여자 환자가 호흡곤란을 주소로 내원하였다. 환자는 과거력상 뇌수술과 기관절개술후 반복되는 흡인으로 인하여 기관전환수술을 시행 받았다. 응급 3차원 나선형 기관단층 촬영술에서 하부기관의 협착이 나타났다. 수술은 정중 흉골절개술을 통하여 글루타르알데하이드에 담근 심막을 이용한 전방기관성형술을 실시하여 좋은 결과를 보았다. 저자들은 이를 치험 하였기에 보고하는 바이다.

• 한국임상수의학회지
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• 제20권4호
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• pp.493-495
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• 2003

A dead, female, 3 years old, squirrel monkey (Saimiri sciureus) was submitted and examined. Before death the monkey has showed lethargy, recumbency and inappetence since November 14, 2001 and died in November 17. Grossly much fibrin was deposited on the pleura of right lung, pericardium, and diaphragm(pleural part). And reddening of right lung was seen. Histopathologically lung showed severe fibrinous pleuritis, severe edema, thrombosis, and focal necrosis in parenchyma. Also much fibrin and mononuclear cells were deposited on the pericardium. In bacterial culture on the pleura and parenchyma of lung, and pericardium, B. bronchiseptica was isolated. Therefore we confirmed this case as the fatal case by B. bronchiseptica in squirrel monkey.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제33권4호
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• pp.359-362
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• 2011

Purpose: This study evaluated the clinical applications of implant placement and guided bone regeneration using a mineralized bone allograft and a barrier membrane derived from ox pericardium Methods: From January 2007 to June 2009, among the patients who received an implant at Chosun University Dental Hospital, patients were selected if they were treated with guided bone regeneration (GBR) with simultaneous implant placement or GBR prior to implant placement. The selected patients were sorted according to the materials and membranes used in GBR, and the implant survival rate was recorded by clinical examination and reviewing the medical records and the radiographs. Each study list was analyzed by SPSS (version 12.0, SPSS Inc., USA) software and the survival rate was verified by Chi-square tests. $P$ values less than 0.05% were deemed significant. Results: 278 implants were placed on a total of 101 patients and 8 implants resulted in failure. Three implants failed among 15 implants with only a mineralized bone allograft. No failure was shown among the 74 implants placed with mineralized bone allograft and a barrier membrane derived from ox pericardium. One group of 4 implant placements showed failure among the 102 implants placed with a mineralized bone allograft and another bone graft material. The group that had a barrier membrane derived from ox pericardium with a mineralized bone allograft or other bone materials showed no implant failure. Three failures were shown among the 21 implants placed with only bone graft and not using a membrane. The group with membranes other than a barrier membrane derived from ox pericardium showed 5 failures among 170 implants. Conclusion: The implant survival rate of the group with GBR using a mineralized bone allograft was 96.3%, which meant there was little difference compared to the groups of another bone graft materials (98.9%). The implant survival rate of the group without a membrane-was 85.7% and it showed a significant difference compared to the group using a barrier membrane derived from ox pericardium (100%) and the group using another membrane (97.1%).