• Journal of Microbiology and Biotechnology
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• v.31 no.12
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• pp.1716-1721
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• 2021

Chikungunya fever is an arboviral disease caused by the Chikungunya virus (CHIKV). The disease has similar clinical manifestations with other acute febrile illnesses which complicates differential diagnosis in low-resource settings. We aimed to develop a rapid test for CHIKV detection based on the nucleic acid lateral flow immunoassay technology. The system consists of a primer set that recognizes the E1 region of the CHIKV genome and test strips in an enclosed cassette which are used to detect amplicons labeled with FITC/biotin. Amplification of the viral genome was done using open-source PCR, a low-cost open-source thermal cycler. Assay performance was evaluated using a panel of RNA isolated from patients' blood with confirmed CHIKV (n = 8) and dengue virus (n = 20) infection. The open-source PCR-NALFIA platform had a limit of detection of 10 RNA copies/ml. The assay had a sensitivity and specificity of 100% (95% CI: 67.56% - 100%) and 100% (95% CI: 83.89% - 100%), respectively, compared to reference standards of any positive virus culture on C6/36 cell lines and/or qRT-PCR. Further evaluation of its performance using a larger sample size may provide important data to extend its usefulness, especially its utilization in the peripheral healthcare facilities with scarce resources and outbreak situations.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.23 no.1
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• pp.15-21
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• 2023

This paper is a study on the development of an artificial intelligence model that recognizes a hole cup on a golf green. A CNN-based object detection algorithm was used to recognize the hole cup on the green. Also, Apple's CreateML was used to create a model of the object detection algorithm. This paper created a JSON file with 120 training images and annotations to meet the needs of CreateML. In addition, for more accurate learning, data amplification algorithm was used for learning data and 288 learning data were used for learning. By changing the Iterations, Batch size, and Grid size required by CreateML, we found parameter values that improve the performance of the model. A prototype app was developed by applying the developed model, and performance was measured on an actual golf course green using the prototype app. As a result of the measurement, it was found that the hole cup was accurately recognized within 10m, which is the typical golfer's putting distance.

• Journal of the Korean Geotechnical Society
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• v.26 no.12
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• pp.61-70
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• 2010

A series of shaking table tests were conducted to estimate the seismic performance of soft ground deposits improved by stone column. The amplification of acceleration, shear strain, and shear wave velocity were evaluated to compare the seismic response of unimproved ground deposits with that of improved ground deposits. From the test results, it was shown that the stone column can prevent large shear deformation in ground deposits. However, it was also found that the acceleration of improved ground deposits may be amplified more than that of unimproved ground deposits when it was subjected to short periodic seismic wave. The results suggest that it is necessary to perform the ground response analysis with model experiments for both unimproved and improved ground deposits to evaluate the effect of stone column on the seismic performance of improved ground deposits.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1978.06a
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• pp.9.2-9
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• 1978

Monaural and binaural hearing aid performance under quiet and noisy conditions were compared in regard to (1) the degree of hearing impairment, (2) the symmetry of pure tone audiogram, (3) the automatic gain control of the hearing aid. (4) hearing impairement with recruitment and, word discrimination ability. Performance using binaural hearing aids was consistently superior to that using monaural hearing aids. The results were as follows. 1. Speech detection thresholds were enhanced by a mean of 4.25dB when tested with danavox 747 PP stereo type hearing aid and by a mean of 4.12 dB when tested hearing aids connected seperately to the right and left ears. 2. Binaurally tested speech reception thresholds were superior to monaurally tested thresholds by a mean of 3.56dB when tested in quiet and by a mean of 5.56dB when tested in noise. 3. Binaurally tested word discrimination scores were also superior by a mean of 17.09% in quiet and by a mean 19.63% in noise. 4. Both SRT and word discrimination scores were performed best by subjects with moderately-severe impairement. The performance by one mildly impaired subject was the poorest of all performances. The levels of performance order were; moderately-severe loss, severe loss. moderate loss and mild loss. 5. The data obtained using AGC aids when compaired with that of linear amplification show that when AGC aids were worn in both ears. the results were very poor but when one AGC aid was worn in one ear and linear amplification in the other. the results were good. 6. The advantages of binaural hearing aids were obvious even in cases 1) with great diferences in hearing thresholds between right and left ears, 2) when the subject was unable to discriminate words without vision and. 3) when the subject had extreme recruitme t phenomenon.

• Journal of the Korean Society for Railway
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• v.19 no.3
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• pp.331-340
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• 2016

Wheel load, design velocity, traffic amount (MGT), stiffness and thickness of sub-layers of asphalt concrete track are selected as performance design parameters in this study. A pseudo-static wheel load computed considering the dynamic amplification factor (DAF) based on the design velocity of the KTX was applied to the top of asphalt concrete track for full three dimensional structural analysis using the ABAQUS program. Tensile strains at the bottom of the asphalt concrete layer and vertical strains at the top of the subgrade were computed from the structural FEA with different combinations of performance parameter values for one asphalt concrete track section. Utilizing the computed structural analysis results such as the tensile strains and the vertical strains, it was possible to develop design graphs to investigate proper track sections for different combination of the performance parameters including wheel load, design velocity, traffic amount(MGT), stiffness and thickness of asphalt concrete layers for any given design life. By analyzing the proposed design graphs for asphalt concrete track, it was possible to propose simple design tables that can be used by engineers for the effective and fast design of track.

• Reproductive and Developmental Biology
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• v.38 no.3
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• pp.123-127
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• 2014

This study was conducted for SNPs in the 5'-regions of estrogen receptor-${\alpha}$ (ESR-${\alpha}$), and association with calving interval (CI), service per conception (SPC) and 305 days milk yield in Hanwoo and Holstein dairy cattle. The genetic improvement was incurred low reproduction performance. The objective of this study was to investigate connections between single nucleotide polymorphisms (SNP) of Estrogen receptor-${\alpha}$ (ESR-${\alpha}$) with reproduction performance (calving interval, service per conception, and 305 d milk yield) in Hanwoo and Holstein dairy cattle. Hanwoo and Holstein blood samples were collected from 183 and 124 dam of breeding farms and DNA was extracted. Primer design was based on NCBI GenBank (Accession No. AY340579). The PCR-RFLP method with Bgl I was used to genotype the cattle. The result showed two variants of the ESR-${\alpha}$ gene. The Bgl I cut the 492 bp amplification product into 322 bp and 170 bp fragments for allele G, while allele A remained uncut, resulting in two restriction fragments for homozygote G/G and three fragments for heterozygote A/G. We found two of different genotypes in these breeds, A/G and G/G. In Hanwoo, the A/G genotype frequency was 0.13, and G/G was 0.87. The CI of A/G was $382.18{\pm}10.03$ days, and G/G was $381.69{\pm}5.22$ days. The SPC of A/G was $1.62{\pm}0.16$, and G/G was $1.32{\pm}0.04$. While CI showed no significance difference, SPC exhibited significant difference (p<0.05). In Holstein cattle, the frequency of genotype A/G was 0.02 and G/G was 0.98. The 305 days milk yield of A/G was $7,253.00{\pm}936.00kg$ and of G/G was $8,747.51{\pm}204.88kg$, showing no significant difference.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.1
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• pp.17-27
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• 2019

In this paper, we study the applicability of Tuned Mass Damper(TMD) to improve seismic performance of piping system under earthquake loading. For this purpose, a mode analysis of the target pipeline is performed, and TMD installation locations are selected as important modes with relatively large mass participation ratio in each direction. In order to design the TMD at selected positions, each corresponding mode is replaced with a SDOF damped model, and accordingly the corresponding pipeline is converted into a 2-DOF system by considering the TMD as a SDOF damped model. Then, optimal design values of the TMD, which can minimize the dynamic amplification factor of the transformed 2-DOF system, are derived through GA optimization method. The proposed TMD design values are applied to the pipeline numerical model to analyze seismic performance with and without TMD installation. As a result of numerical analyses, it is confirmed that the directional acceleration responses, the maximum normal stresses and directional reaction forces of the pipeline system are reduced, quite a lot. The results of this study are expected to be used as basic information with respect to the improvement of the seismic performance of the piping system in the future.

• Journal of the Earthquake Engineering Society of Korea
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• v.9 no.4 s.44
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• pp.11-18
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• 2005

Inelastic seismic analysis is necessary for the seismic design due to the nonlinear behavior of a structure-soil system, and the importance of the performance based design considering the soil-structure interaction is recognized for the reasonable seismic design. In this study, elastic and inelastic seismic response analyses of a single degree of freedom system on the soft soil layer were peformed considering the nonlinearity of the soil for the 11 weak or moderate, and 5 strong earthquakes scaled to the nominal peak acceleration of 0.075g, 0.15g, 0.2g and 0.3g. Seismic response analyses for the structure-soil system were peformed in one step applying the earthquake motions to the bedrock In the frequency domain, using a pseudo 3-D dynamic analysis software. Study results indicate that it is necessary to consider the nonlinear soil-structure interaction effects and to perform the performance based seismic design for the various soil layers rather than to follow the routine procedures specified in the seismic design codes. Nonlinearity of the soft soil excited with the weak earthquakes also affected significantly to the elastic and inelastic responses due to the nonlinear soil amplification of the earthquake motions, and it was pronounced especially for the elastic ones.

• Korean Journal of Remote Sensing
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• v.39 no.6_2
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• pp.1529-1539
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• 2023

The data from Geostationary Ocean Color Imager-II (GOCI-II), which observes the color of the sea to monitor marine environments, undergoes various correction processes in the ground station system, producing data from Raw to Level-2 (L2). Quality issues arising at each processing stage accumulate step by step, leading to an amplification of errors in the satellite data. To address this, improvements were made to the GOCI-II ground station system to measure potential optical quality and geolocation accuracy errors in the Level-1A/B (L1A/B) data. A newly established Radiometric and Geometric Performance Assessment Module (RGPAM) now measures five optical quality factors and four geolocation accuracy factors in near real-time. Testing with GOCI-II data has shown that RGPAM's functions, including data processing, display and download of measurement results, work well. The performance metrics obtained through RGPAM are expected to serve as foundational data for real-time radiometric correction model enhancements, assessment of L1 data quality consistency, and the development of reprocessing strategies to address identified issues related to the GOCI-II detector's sensitivity degradation.

• International Journal of Control, Automation, and Systems
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• v.4 no.6
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• pp.748-755
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• 2006

In this paper, a trade-off design and fabrication of IPMC(Ionic Polymer Metal Composites) as an actuator for a flapping device have been described. Experiments for the internal solvent loss of IPMCs have been conducted for various combinations of cation and solvent in order to find out the best combination of cation and solvent for minimal solvent loss and higher actuation force. From the experiments, it was found that IPMCs with heavy water as their solvent could operate longer. Relations between length/thickness and tip force of IPMCs were also quantitatively identified for the actuator design from the tip force measurement of 200, 400, 640, and $800{\mu}m$ thick IPMCs. All IPMCs thicker than $200{\mu}m$ were processed by casting $Nafion^{TM}$ solution. The shorter and thicker IPMCs tended to generate higher actuation force but lower actuation displacement. To improve surface conductivity and to minimize solvent evaporation due to electrically heated electrodes, gold was sputtered on both surfaces of the cast IPMCs by the Physical Vapor Deposition(PVD) process. For amplification of a short IPMC's small actuation displacement to a large flapping motion, a rack-and-pinion type hinge was used in the flapping device. An insect wing was attached to the IPMC flapping mechanism for its flapping test. In this test, the wing flapping device using the $800{\mu}m$ thick IPMC. could create around $10^{\circ}{\sim}85^{\circ}$ flapping angles and $0.5{\sim}15Hz$ flapping frequencies by applying $3{\sim|}4V$.