• 한국분무공학회지
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• 제6권4호
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• pp.39-48
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• 2001

The Gasoline Direct Injection(GDI) system has been highlighted due to the improvement of fuel consumption and the control of exhaust emission from gasoline engines. Main purpose of the present study is to measure spray characteristics of GDSI for real engine application. We have investigated experimentally spray tip penetration, spray angle, tip velocity and spatial spray distribution. Counter-rotating vortex grown on the spray surface plays an important role in the spray characteristics. Accordingly the spray tip penetration and tip velocity do not excess 50mm, 20m/s respectively, under 0.6MPa ambient pressure. the spray cone angle of GDSI have a same tendency to a simplex swirl atomizer.

• 한국군사과학기술학회지
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• 제14권6호
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• pp.1114-1120
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• 2011

Shaped Charge's penetration performance is depended on the shape of warhead and explosive, liner materials. The liner that manufactured to small homogeneous grain increase the penetration performance and decrease the deviation of penetration performance. This texture is obtained by forging process but, creating the process that remove crack and get small homogeneous grain is very hard. In this study, We success to get the homogeneous small grain texture through appling the most suitable process by DEFORM CODE analysis.

• Journal of Welding and Joining
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• 제20권1호
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• pp.69-75
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• 2002

This study investigated the effect of the system parameters on penetration depth measurement using infrared temperature sensing system. The distance from focusing lens to detector was varied to diminish the error in measuring weld bead width. The effect of bead surface shape on measured surface temperature profile was evaluated using specimen heated by electric resistance. The measuring distance from laser beam was changed to optimize the measuring point. The results indicated that the monitoring device of surface temperature using infrared detector array was applicable to real time penetration depth control.

• 농업과학연구
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• 제43권2호
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• pp.194-204
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• 2016

The pear psylla, Cacopsylla pyricola, is a very small sap-feeding insect of many commercial pear varieties that could be considered the most serious insect pest of pear. Detailed information on plant penetration activities of the pear psylla is essential to study its feeding behavior used to evaluate resistant traits to chemical control. The application of the electrical penetration graph technique (EPG) could provide a relevant insight into the nature of this resistance. EPG waveforms of C. pyricola were characterized on the basis of amplitude, frequency, voltage level, and electrical origin. Feeding behaviors of C. pyricola were recorded and analyzed by EPG analysis. During EPG monitoring, waveform PA occurred at the start of stylet penetration of pear leaf epidermal cell. Waveform PB followed, in which stylet secreted saliva was observed. Waveforms PC1 and PC2 involved penetrating and sucking behaviors in parenchyma cells and vascular parenchyma, respectively. In addition, waveform PC1 represented salivation into bundle sheath cells and ingestion from parenchyma. Otherwise, behaviors of salivation into phloem and ingestion from phloem produced waveforms PE1 and PE2, respectively. On the other hand, ingestion from xylem tissues showed waveform PG. Among the feeding patterns of C. pyricola described above, phloem feeding patterns occurred most frequently, followed by xylem feeding and parenchyma penetration patterns in descending order.

• Biomolecules & Therapeutics
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• 제19권2호
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• pp.231-236
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• 2011

The aim of this study was to investigate the effect of charge carrier lipid on the skin penetration, retention, and hair growth of topically applied finasteride-containing liposomes. Finasteride-containing liposomes were prepared by traditional thin film hydration method using Phospholipon$^{(R)}$ 85 G and cholesterol with or without charge carrier lipid (1,2 dimyristoyl-sn-glycero-3-phosphate or 1,2-dioleoyl-trimethylammonium-propane for anionic and cationic charge, respectively). Freshly prepared finasteride-containing liposome suspension was applied on the hairless mouse skin, and skin penetration and retention were measured using Keshary-Chien diffusion cell. Non-liposomal formulation (ethanol 10% solution containing 0.5 mg/ml of FNS) was also used as a control. The amount of finasteride in the diffusion cell and mouse skin was measured by HPLC. The hair growth was evaluated using depilated male C57BL/6N mice. Mean particle size of all finasteride-containing liposomes was less than a micron, and polydispersity index revealed size homogeneity. Skin penetration and retention studies showed that significantly less amount of finasteride was penetrated when applied as anionic liposome while more amount of the drug was retained. Specifically, in liposome prepared with 10% anionic charge carrier lipid, penetration was 12.99 ${\mu}g/cm^2$ while retention was 79.23 ${\mu}g/cm^2$ after 24 h of application. In hair growth study, finasteride-containing anionic liposomes showed moderate efficacy, but the efficacy was not found when applied as cationic liposomes. In conclusion, topical application of finasteride using anionic liposome formulation appears to be useful option for the treatment of androgenetic alopecia to avoid systemic side effects of the drug.

• Restorative Dentistry and Endodontics
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• 제26권5호
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• pp.379-386
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• 2001

This study was performed to evaluate the sealing ability of various retrograde filling materials by using bacterial penetration and dye penetration test. One hundred and forty extracted human teeth with single, straight canals and mature apiece were collected and used for this study. All canals were instrumented using an engine driven Ni-Ti file (ProFile). After removing 3mm from the apex of tooth, a standardized 3mm root end cavity was prepared using an ultrasonic instrument. The 70 teeth were randomly divided into 7 groups : 6 groups for retrograde filling using Super-EBA, ZOE, Chelon-Silver, IRM, ZPC and amalgam. The 7th group was used as a negative control. Nail varnish was applied to all external root surfaces to the level of the reseated root ends to prevent lateral microleakages. The specimens were then sterilized in an ethylene oxide sterilizer for 24 hours. 2 mm of the reseated root was immersed in a culture chamber containing a Tripticase Soy Broth with a phenol red indicator. The coronal access of each specimen was inoculated every 72 hours with suspension of Proteus vulgaris. The culture media were observed every 24hours for color change indicating bacterial contamination. The specimens were observed for 4weeks. The remaining 70 teeth were submitted to a dye penetration test. The canals of all teeth were first sealed with AH26 and obturated using an Obtura II system. Root resection, root end preparation and retrograde filling was performed as above. All specimens were suspended in 2% methylene blue dye for 72 hours before being ion gitudinally split. The degree of dye penetration was then measured using a stereomicroscope at 10 magnification and evaluated. The results were as floows : 1. In the bacterial penetration, the degree of leakage was the lowest in the Super-EBA, followed by, in ascending order, ZOE, Chelon-Silver IRM and ZPC. The amalgam showed highest bacterial leakage of all(p<0.01). 2. In the dye penetration, the degree of microleakage was the lowest in the Chelon-Silver and Super-EBA, followed by, in ascending order, IRM, ZPC. The ZOE and amalgam showed the highest microleakage of all (p<0.05). These results suggested that the eugenol based cement, Super-EBA, have excellent sealing ability as a retrograde filling material.

• 한국지반공학회지:지반
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• 제14권1호
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• pp.49-58
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• 1998

폐타이어가 지반의 동상방지 건설재료로서 재사용될 수 있는지를 연구하였다. 동상방지에 대한 폐타이어의 기본적인 효과를 검토하기 위해 화강풍화토에 폐타이어가루를 몇 가지의 비율로 혼합해서 준비한 시료로서 영하 $17^{\circ}$하에서 동상시험과 화강풍화토에 대한 동결깊이시험을 실내에서 수행하였다. 역청포장의 보조기층 바로 아래에 폐타이어조각을 혼합한 쇄석층을 동상방지층으로 둠으로서 실용상으로 효과적이라는 사실을 알게 되었다. 그리고 이 동상방지 층의 소요두께와 동결 지수와의 관계식을 제안하였다.

• 한국환경농학회지
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• 제42권2호
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• pp.104-111
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• 2023

As apple trees mature, it is important to maintain good light distribution within the canopy to produce marketable fruits. Tree thinning is the selective removal of a proportion of trees growing in the orchard to provide more growing space and a good light environment for the remaining trees. This study was conducted over 3 years (14-16 years after planting) to investigate the influence of tree thinning on vegetative growth, yield, fruit quality, and blooming in the 14 years old slender spindle 'Fuji'/M.9 apple trees planted with the tree space of 3.2×1.2 m. The trees were placed in a control group (no thinning; 260 trees per 10 a) or a tree thinning group (thinned 50% of the control; 130 trees per 10 a). The tree thinning successfully improved light penetration, yield per tree, fruit red color, and yield efficiency for 3 years, and the tree thinning controlled the occurrence of biennial bearing. However, tree thinning significantly decreased accumulated yield per 10 a compared with the control. The vegetative growth, yield per tree, soluble solid contents, and blooming were not clear by the occurrence of biennial bearing in the control. These results indicated that tree thinning was a good method for improving light penetration and preventing biennial bearing in the old 'Fuji'/M.9 high-density apple orchards.

• Journal of Pharmaceutical Investigation
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• 제33권3호
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• pp.157-162
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• 2003

The feasibility of [P(AA-co-PEGMM)] film as a buccal mucoadhesive patch was previously reported by estimating mucoadhesiveness and release characteristics. To find a rational penetration enhancer of [P(AA-co-PEGMM)] film containing butorphanol tartrate (Bt), penetration of Bt from [P(AA-co-PEGMM)] film which contained various additives was estimated by measuring its flux, Papp and lag tme in in vitro buccal membrane of porcine. EDTA showed almost no increase of Bt permeability, wherease SGC, STDHF and SLS increased the permeability of Bt with the order of SGC > STDHF > SLS. The rational additive concentration of SGC was 4% and its Papp and lag time were $1.93{\times}10^{-4}{\pm}4.21{\times}10^{-6},\;126.60{\pm}21.88min\;(control\;:\;Papp\;0.45{\times}10^{-4};\;lag\;time\;211.01{\pm}16.77\;min)$, respectively.

• Reproductive and Developmental Biology
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• 제34권1호
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• pp.21-25
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• 2010

The purpose of this study was to investigate the effects of the collection time, co-culture and sperm penetration of canine oocytes on in vitro maturation and fertilization. The oocytes were cultured in TCM-199 media containing hormonal supplements (10% FCS, 10 IU/ml HCG, 10 IU/ml PMSG) at 5% $CO_2$, 95% air, $38^{\circ}C$. The in vitro maturation rate to MII stage of in vitro oocytes recovered from ovaries that collected at follicular, luteal and inactive phases of the reproductive phase for 44~72 hrs were 19.2%, 12.2%, and 6.0%, respectively. Follicular phases oocytes had a significantly higher in vitro maturation rate than oocytes collected at luteal and anestrus stage (p<0.05). The in vitro maturation rates to the MII stage of canine oocytes after 48 hrs of culture with glutathione, pyruvate, or glutathione + pyruvate were 12.5%, 10.7%, and 17.5%, respectively. This was higher than that in both alone or the combination of the two compared to the control group (19.0%). The sperm penetration rates of in vitro matured oocytes by fresh and frozen semen were 29/80 (36.3%) and 18/80 (22.5%), respectively. Although there are limited reports about canine oocytes co-culture and in vitro fertilization, our results on in vitro maturation is comparable to the results from other researches.