• Computers and Concrete
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• v.12 no.4
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• pp.565-583
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• 2013

Existing numerical models for strain-hardening cement-based composites (SHCC) are short of providing sufficiently accurate solutions to the failure patterns of coupling beams of different designs. The objective of this study is to develop an effective model that is capable of simulating the nonlinear behavior of SHCC coupling beams subjected to cyclic loading. The beam model proposed in this study is a macro-scale plane stress model. The effects of cracks on the macro-scale behavior of SHCC coupling beams are smeared in an anisotropic model. In particular, the influence of the defined crack orientations on the simulation accuracy is explored. Extensive experimental data from coupling beams with different failure patterns are employed to evaluate the validity of the proposed SHCC coupling beam models. The results show that the use of the suggested shear stiffness retention factor for damaged SHCC coupling beams is able to effectively enhance the simulation accuracy, especially for shear-critical SHCC coupling beams. In addition, the definition of crack orientation for damaged coupling beams is found to be a critical factor influencing the simulation accuracy.

• Radiation Oncology Journal
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• v.33 no.1
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• pp.29-35
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• 2015

Purpose: To analyze the prognostic factors for survivals and to evaluate the impact of postoperative whole pelvic radiotherapy (WPRT) on pelvic failure in patients with uterine sarcoma treated with radical surgery. Materials and Methods: We retrospectively analyzed 75 patients with uterine sarcoma who underwent radical surgery with (n = 22) or without (n = 53) radiotherapy between 1990 and 2010. There were 23 and 52 patients with carcinosarcoma and non-carcinosarcoma (leiomyosarcoma, 22; endometrial stromal sarcoma, 25; others, 5), respectively. The median follow-up period was 64 months (range, 17 to 269 months). Results: The 5-year overall survival (OS) and pelvic failure-free survival (PFFS) of total patients was 64.2% and 83.4%, respectively. Multivariate analysis revealed that mitotic count (p = 0.006) was a significant predictor of OS. However, factors were not found to be associated with PFFS. On analyzing each of the histologic subtypes separately, postoperative WPRT significantly reduced pelvic failure in patients with carcinosarcoma (10.0% vs. 53.7%; p = 0.046), but not in patients with non-carcinosarcoma (12.5% vs. 9.9%; p = 0.866). Among the patients with carcinosarcoma, 4 patients (17%) had recurrence within the pelvis and 3 patients (13%) had recurrence in other sites as an initial failure, whereas among the patients with non-carcinosarcoma, 3 patients (6%) experienced pelvic failure and 13 patients (25%) experienced distant failure. Conclusion: The most significant predictor of OS was mitotic count. Based on the improved PFFS after postoperative WPRT only in patients with carcinosarcoma and the difference in patterns of failure between histologic subtypes, optimal adjuvant treatment options should be offered to patients based on the risk of recurrence patterns.

• Proceedings of the Korean Geotechical Society Conference
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• 2000.11a
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• pp.527-534
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• 2000

136 cut slopes which extends from Namyangju to Chunchon city along the 46th national highway were investigated to analyze the influence factors affecting slope instability. Geologic and geotechnical conditions were examined and the detailed investigation were carried out for fifty five failed slopes. failure mode (wedge failure, planar failure, circular failure, sheet eroison and rock falls) are examined with respect to slope inclination, rock type, weathering grade and discontinuity patterns. It is suggested that the failure modes and their dimensions have relations to the morphology and geologic conditions of the slopes. Wedge failure has highest is the most frequent failure mode and falls, sheet erosions, planar failures and circular in descending order of failure percentage. Wedge failure is most dominant failure type over all lithology except quartzite formation. In slopes of well foliated and banded gneiss, failure ratio of wedge is up to 50% ca. Failure ratio(number of rock fall/number of total failure) of rock fall increases with increase fo slope inclinations and decrease of weathering grade. Dimension analyses of failed slopes shows wedge and circular failure has higher value of D/L and D/H than planar failure and sheet erosion.

• Geomechanics and Engineering
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• v.22 no.3
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• pp.219-226
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• 2020

Unconfined compression test (UCT) is widely conducted in laboratories to evaluate the mechanical behavior of frozen soils. However, its results are sensitive to the initial conditions of sample creation by freezing as well as the end-surface conditions during loading of the specimen into the apparatus for testing. This work compared ice samples prepared by three-dimensional and one-dimensional freezing. The latter created more-homogenous ice samples containing fewer entrapped air bubbles or air nuclei, leading to relatively stable UCT results. Three end-surface conditions were compared for UCT on ice specimens made by one-dimensional freezing. Steel disc cap with embedded rubber was found most appropriate for UCT. Three frozen materials (ice, frozen sand, and frozen silt) showed different failure patterns, which were classified as brittle failure and ductile failure. Ice and frozen sand showed strain-softening, while frozen silt showed strain-hardening. Subsequent investigation considered the influence of fines content on the unconfined compression behavior of frozen soil mixtures with fines contents of 0-100%. The mixtures showed a brittle-to-ductile transition of failure patterns at 10%-20% fines content.

• Geomechanics and Engineering
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• v.24 no.1
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• pp.81-89
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• 2021

Uniaxial compression tests were conducted on sandstone-CGFB composite samples with different interface angles, and their strength, acoustic emission (AE), and failure characteristics were investigated. Three macro-failure patterns were identified: the splitting failure accompanied by local spalling failure in CGFB (Type-I), the mixed failure with small sliding failure along with the interface and Type-I failure (Type-II), and the sliding failure along with the interface (Type-III). With an increase of interface angle β measured horizontally, the macro-failure pattern changed from Type-I to Type-II, and then to Type-III, and the uniaxial compressive strength and elastic modulus generally decreased. Due to the small sliding failure along with the interface in the composite sample with β of 45°, AE events underwent fluctuations in peak values at the later post-peak failure stage. The composite samples with β of 60° occurred Type-III failure before the completion of initial compaction stage, and the post-peak stress-time curve initially exhibited a slow decrease, followed by a steep linear drop with peaks in AE events.

• International Journal of Aeronautical and Space Sciences
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• v.18 no.3
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• pp.436-449
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• 2017

In this paper, the damage and failure behavior of triaxially braided textile composites was studied using progressive failure analysis. The analysis was performed at both micro and meso-scales through iterative cycles. Stress based failure criteria were used to define the failure states at both micro- and meso-scale models. The stress-strain curve under uniaxial tensile loading was drawn based on the load-displacement curve from the progressive failure analysis and compared to those by test and computational results from reference for verification. Then, the detailed failure initiation and propagation was studied using the verified model for both tensile and compression loading cases. The failure modes of each part of the model were assessed at different stages of failure. Effect of ply stacking and number of unit cells considered were then investigated using the resulting stress-strain curves and damage patterns. Finally, the effect of matrix plasticity was examined for the compressive failure behavior of the same model using elastic, elastic - perfectly plastic and multi-linear elastic-plastic matrix properties.

• Proceedings of the Korea Concrete Institute Conference
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• 2006.05a
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• pp.366-369
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• 2006

Deformability of RC members in shear is controlled by governing failure modes and material strength. Shear strength of members in D-regions has been explained by a direct load path (direct strut or arch action) and indirect load path (fan action or truss action). Indirect load path including truss action and fan action rely on bond along tension ties. Generally, superposition of two actions results in total shear strength when shear failure modes control. The ultimate deformation depends on controlling failure modes and thereby, their force transfer patterns. Proposed models are capable of explaining of limited deformability of RC members in D-regions.

• Proceedings of the Korean Society for Rock Mechanics Conference
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• 2011.09a
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• pp.3-21
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• 2011

Laboratory experiments and numerical simulations using Particle Flow Code (PFC2D) were performed to study the effects of joint separation and joint overlapping on the full failure behavior of rock bridges under direct shear loading. Through numerical direct shear tests, the failure process is visually observed and the failure patterns are achieved with reasonable conformity with the experimental results. The simulation results clearly showed that cracks developed during the test were predominantly tension cracks. It was deduced that the failure pattern was mostly influenced by both of the joint separation and joint overlapping while the shear strength is closely related to the failure pattern and its failure mechanism. The studies revealed that shear strength of rock bridges are increased with increasing in the joint separation. Also, it was observed that for a fixed cross sectional area of rock bridges, shear strength of overlapped joints are less than the shear strength of non-overlapped joints.

• Clinical and Experimental Pediatrics
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• v.60 no.3
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• pp.64-69
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• 2017

Purpose: The goal of nutritional support for very-low-birth-weight (VLBW) infants from birth to term is to match the in utero growth rates; however, this is rarely achieved. Methods: We evaluated postdischarge growth patterns and growth failure in 81 Korean VLBW infants through a retrospective study. Weight and height were measured and calculated based on age percentile distribution every 3 months until age 24 months. Growth failure was defined as weight and height below the 10th percentile at 24 months. For the subgroup analysis, small-for-gestational age (SGA) and extremely low birth weight (ELBW) infants were evaluated. The growth patterns based on the Korean, World Health Organization (WHO), or Centers for Disease Control and Prevention (CDC) standard were serially compared over time. Results: At postconception age (PCA) 40 weeks, 47 (58%) and 45 infants (55%) showed growth failure in terms of weight and height, respectively. At PCA 24 months, 20 infants (24%) showed growth failure for weight and 14 (18%) for height. Growth failure rates were higher for the SGA infants than for the appropriate-weight-for-gestational age infants at PCA 24 months (P=0.045 for weight and P=0.038 for height). Growth failure rates were higher for the ELBW infants than for the non-ELBW infants at PCA 24 months (P<0.001 for weight and P=0.003 for height). Significant differences were found among the WHO, CDC, and Korean standards (P<0.001). Conclusion: Advancements in neonatal care have improved the catch-up growth of VLBW infants, but this is insufficient. Careful observation and aggressive interventions, especially in SGA and ELBW infants, are needed.

• Korean Journal of Radiology
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• v.21 no.7
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• pp.908-918
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• 2020

Objective: To categorize the radiological patterns of recurrence after bevacizumab treatment and to derive the pooled proportions of patients with recurrent malignant glioma showing the different radiological patterns. Materials and Methods: A systematic literature search in the Ovid-MEDLINE and EMBASE databases was performed to identify studies reporting radiological recurrence patterns in patients with recurrent malignant glioma after bevacizumab treatment failure until April 10, 2019. The pooled proportions according to radiological recurrence patterns (geographically local versus non-local recurrence) and predominant tumor portions (enhancing tumor versus non-enhancing tumor) after bevacizumab treatment were calculated. Subgroup and meta-regression analyses were also performed. Results: The systematic review and meta-analysis included 17 articles. The pooled proportions were 38.3% (95% confidence interval [CI], 30.6-46.1%) for a geographical radiologic pattern of non-local recurrence and 34.2% (95% CI, 27.3-41.5%) for a non-enhancing tumor-predominant recurrence pattern. In the subgroup analysis, the pooled proportion of non-local recurrence in the patients treated with bevacizumab only was slightly higher than that in patients treated with the combination with cytotoxic chemotherapy (34.9% [95% CI, 22.8-49.4%] versus 22.5% [95% CI, 9.5-44.6%]). Conclusion: A substantial proportion of high-grade glioma patients show non-local or non-enhancing radiologic patterns of recurrence after bevacizumab treatment, which may provide insight into surrogate endpoints for treatment failure in clinical trials of recurrent high-grade glioma.