• Parasites, Hosts and Diseases
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• 제52권1호
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• pp.105-109
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• 2014

Plasmodium falciparum malaria is a major public health problem in Thailand due to the emergence of multidrug resistance. The understanding of genetic diversity of malaria parasites is essential for developing effective drugs and vaccines. The genetic diversity of the merozoite surface protein-1 (PfMSP-1) and merozoite surface protein-2 (PfMSP-2) genes was investigated in a total of 145 P. falciparum isolates collected from Mae Sot District, Tak Province, Thailand during 3 different periods (1997-1999, 2005-2007, and 2009-2010). Analysis of genetic polymorphisms was performed to track the evolution of genetic change of P. falciparum using PCR. Both individual genes and their combination patterns showed marked genetic diversity during the 3 study periods. The results strongly support that P. falciparum isolates in Thailand are markedly diverse and patterns changed with time. These 2 polymorphic genes could be used as molecular markers to detect multiple clone infections and differentiate recrudescence from reinfection in P. falciparum isolates in Thailand.

• 기술혁신학회지
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• 제7권1호
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• pp.42-63
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• 2004

Recent trend of rapid growth in the basic research activities in East-Asian newly industrialized countries bring about the change in the world knowledge production structure. Particularly, Korea showed the changing patterns not only in the number of publication, but also in the aspect of structural change of basic research activities. The stylized facts of basic research activities in Korea can be summarized in three aspects; first, selective development patterns, second, reverse pattern of evolution, and finally, the rapid growth of basic research activities in major firms. This paper analyse the evolutionary patterns of basic research activities in empirical base and propose the policy implication for supporting basic research activity in newly industrializing countries.

• Interaction and multiscale mechanics
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• 제1권4호
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• pp.423-435
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• 2008

This paper employs the reproducing kernel (RK) approximation for evaluation of field theory-based incompatibility tensor in a polycrystalline plasticity simulation. The modulation patterns, which is interpreted as mimicking geometrical-type dislocation substructures, are obtained based on the proposed method. Comparisons are made using FEM and RK based approximation methods among different support sizes and other evaluation conditions of the strain gradients. It is demonstrated that the evolution of the modulation patterns needs to be accurately calculated at each time step to yield a correct physical interpretation. The effect of the higher order strain derivative processing zone on the predicted modulation patterns is also discussed.

• 한국실내디자인학회논문집
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• 제21권2호
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• pp.35-45
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• 2012

The development of digital media made the change of architectural paradigm from tectonic to the surface and pattern. This means the transition to the new kind of materiality and the resurrection of ornament. This study started as an aim to apply biological pattern to architectural design from the new perception of pattern. Architectural patterns in the early era appeared as ladders, steps, chains, trees, vortices. But since 21st century, we can find patterns in nature like atoms and molecular structures, fluid forms of dynamics and new geometrical pattern like fractal and first of all biological patterns like viruses and micro-organisms, Voronoi cells, DNA structure, rhizomes and various hybrids and permutations of these. Pattern became one of the most important elements and themes of contemporary architecture through the change of materiality and resurrection of ornament with the new perception of surface in architecture. One of the patterns that give new creative availability to the architectural design is biological pattern which is self-organized as an optimum form through interaction with environment. Biological patterns emerge mostly as self-replicating patterns through morphogenesis, certain geometrical patterns(in particular triangles, pentagons, hexagons and spirals). The architectural application methods of biological patterns are direct figural pattern of organism, circle pattern, polygon pattern, energy-material control pattern, differentiation pattern, parametric pattern, growth principle pattern, evolutionary ecologic pattern. These patterns can be utilized as practical architectural patterns through the use of computer programs as morphogenetic programs like L-system, MoSS program and genetic algorithm programs like Grasshoper, Generative Components with the help of computing technology like mapping and scripting.

• Current Applied Physics
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• 제18권11호
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• pp.1235-1239
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• 2018

We present a novel process to fabricate three-dimensional (3D) metallic patterns from 3D printed polymeric structures utilizing different hygroscopic swelling behavior of two different polymeric materials. 3D patterns are printed with two different polymers as cube shape. The surface of the 3D printed polymeric structures is plated with nickel by an electroless plating method. The nickel patterns on the surface of the 3D printed cube shape structure are formed by removing sacrificial layers using the difference in the rate of hygroscopic swelling between two printing polymer materials. The hygroscopic behavior on the interfaced structure was modeled with COMSOL Multiphysics. The surface and electrical properties of the fabricated three-dimensional patterns were analyzed and characterized.

• International Journal of Advanced Culture Technology
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• 제11권1호
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• pp.253-262
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• 2023

Chinese traditional patterns, which are part of our national precious heritage, have a long history. Tiger culture plays a very important role in folk art. In modern society, it is a symbol of human spirit and morality. The tiger pattern is also a unique traditional pattern in Chinese folklore. From the Spring and Autumn period to modern society, the tiger pattern has evolved in form through thousands of years of development. It is also a representative intangible cultural heritage in contemporary times. It plays a special role in the cultural exchange of different regions, resulting in the generation of the creation of folk art with great local characteristics. Therefore, traditional tiger patterns are an important part of traditional Chinese folk culture and art. In this study, by analyzing the development and evolution history of Chinese traditional tiger patterns, the application methods of Chinese traditional tiger patterns were summarized, the rich cultural connotation, artistic characteristics and application of traditional tiger pattern in modern fashion design were discussed. In contemporary design, the new and improved tiger pattern styles were explored, intangible cultural heritage was interpreted and inherited, and the cultural and artistic values contained therein were extracted. The author combined with modern fashion design, according to people's aesthetic taste and design principles, it is recreated,so that the traditional pattern has certain characteristics of The Times.But at the same time it retains its original character,and the traditional tiger pattern was inherited and the cultural connotation of clothing design was enriched.

• 천문학회보
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• 제38권1호
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• pp.31.1-31.1
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• 2013

Barred-spiral galaxies possess double patterns: a bar and spiral arms. While their angular speeds play an important role in governing gas dynamical evolution of barred spiral galaxies, there is no direct way to observe them. The Tremaine-Weinberg (TW) method has been one of the most reliable indirect methods to estimate pattern speeds, although it requires a few strict assumptions, notably one that the gas tracer is in a quasi-steady state. In barred-spiral galaxies, however, non-steady gas flows are significant especially when the double patterns have different angular speeds. Using numerical models, we explore the effect of non-steady gas motions on the determination of double pattern speeds based on the TW method. We find that the TW method is accurate within 15% when there is only a single pattern or when double patterns have the same angular speed. When double patterns have different speeds, on the other hand, neglecting the non-steady flows leads to quite large errors (> 30%) in the derived pattern speeds, and severely underestimate the real values for the viewing angle parallel to the bar minor axis. This suggests that one should be cautious when applying the TW method to galaxies with double patterns with different speeds.

• 대한교통학회지
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• 제32권5호
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• pp.522-530
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• 2014

교통관리센터에 축적되어 있는 속도 이력데이터에는 반복 비반복 정체 시공간 전개에 대한 상세한 정보가 모두 들어있으나, 도해법에 의해 다루어져 왔기 때문에 많은 양의 이력데이터를 처리하여 교통상황예측이나 정보제공에 활용할 수 없는 한계가 존재하였다. 본 논문에서는, 기존의 Classification과 Density-Based Clustering 알고리즘을 속도 시공간 데이터 특성에 맞게 조합하고 변형하여 정체 시공간 영역을 자동 인식하는 알고리즘과, 정체파급길이, 파급속도, 해소속도 등 정체 시공간 전개 패턴의 특성치를 산정하는 알고리즘을 개발하였다, 본 알고리즘은, 교통관리센터에 축적되어 있는 방대한 양의 이력데이터를 자동으로 분석하여 자세한 정체 관련 정보를 추출할 수 있고, 산정된 특성치를 가지고 각 센터의 필요에 따라 다양한 정보를 2차 생성하고 활용할 수 있는 장점이 있다. 본 연구결과는 향후 반복 비반복 정체에 대한 예측과 대응이 획기적으로 개선되는데 초석이 될 것으로 기대된다.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제15권5호
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• pp.375-379
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• 2009

도메인은 단백질의 진화와 삼차구조 및 분자 기능의 기본 단위체이다. 단백질은 한 개 이상의 도메인들로 구정 되며, 단백질의 기능 또한 각 도메인이 가진 기능의 집합으로 구현된다. 단백질은 특정 기능을 담당하기 위해 진화되어 왔으므로, 도메인 또한 단백질 내에서 기능을 위한 특정 조합 패턴, 즉 보존도메인 조합을 가진다. 본 논문은 각 도메인 조합의 진화상 보존 정도를 측정할 수 있는 연관성 규칙 기반 계산 기법을 제안한다. 제안된 기법은 기존 기법에서 주로 고려되었던 도메인 조합의 빈도뿐 아니라, 조합 내 소속 도메인간의 상호 의존도를 측정하여 주어진 조합의 보존 정도를 산출한다. 이를 기반으로 S.cerevisiae의 단백질을 대상으로 보존 도메인 조합을 추출하였으며, Gene Ontology를 이용하여 그 생물학적 의미를 분석하였다. 그 결과 제안된 기법으로 추출된 보존 도메인 조합은 기존의 것에 비해 조합 내 기능의 유사도가 높았으며, 따라서 제안된 기법이 생물학적 기능의 협업 위해 보존된 도메인 조합의 추출에 우수하다 할 것이다. 또한 S.cerevisiae 단백질체에는 서로 의존도가 높고 자주 나타나는 보존 도메인 조합이 존재하며, 그러한 조합들은 molecular function의 협업과 관련 있음을 밝혀냈다.

• 식물분류학회지
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• 제42권1호
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• pp.13-23
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• 2012

trnL-F 지역은 엽록체 게놈 large single-copy 지역에 위치하며, trnL gene, trnL intron, trnL-F IGS로 구성된다. 본 연구는 한국산 꿩의다리속 내에서 trnL-F 지역의 분자진화와 유연관계를 분석하였다. 갭형질을 이용한 자료의 베이시안과 파시모니 분석에서 몇몇 indels evolution는 분계조를 지지하여 해상력이 좋은 계통수가 나타났다. 한국산 꿩의다리속 내에 cpDNA trnL-F 지역의 indel events는 계통학적으로 유용한 정보를 가지고 있는 것으로 판단된다. 산꿩의다리절(그늘꿩의다리 제외)은 속내에서 가장 먼저 분기한 것으로 나타났고, 나머지 절은 강하게 분계조를 형성하며 분기하였다. 한국산 꿩의다리속 내에 trnL-F 지역은 뉴클레오티드의 다양한 공간적 분포 변이와 주로 transversion에 따른 염기치환 등 다양한 진화적 패턴을 가지고 있었다.