• Title/Summary/Keyword: Patterns of Danger

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Roles of ginsenosides in inflammasome activation

  • Yi, Young-Su
    • Journal of Ginseng Research
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    • v.43 no.2
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    • pp.172-178
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    • 2019
  • Inflammation is an innate immune response that protects the body from pathogens, toxins, and other dangers and is initiated by recognizing pathogen-associated molecular patterns or danger-associated molecular patterns by pattern-recognition receptors expressing on or in immune cells. Intracellular pattern-recognition receptors, including nucleotide-binding oligomerization domain-like receptors (NLRs), absent in melanoma 2, and cysteine aspartate-specific protease (caspase)-4/5/11 recognize various pathogen-associated molecular patterns and danger-associated molecular patterns and assemble protein complexes called "inflammasomes." These complexes induce inflammatory responses by activating a downstream effector, caspase-1, leading to gasdermin D-mediated pyroptosis and the secretion of proinflammatory cytokines, such as interleukin $(IL)-1{\beta}$ and IL-18. Ginsenosides are natural steroid glycosides and triterpene saponins found exclusively in the plant genus Panax. Various ginsenosides have been identified, and their abilities to regulate inflammatory responses have been evaluated. These studies have suggested a link between ginsenosides and inflammasome activation in inflammatory responses. Some types of ginsenosides, including Rh1, Rg3, Rb1, compound K, chikusetsu saponin IVa, Rg5, and Rg1, have been clearly demonstrated to inhibit inflammatory responses by suppressing the activation of various inflammasomes, including the NLRP3, NLRP1, and absent in melanoma 2 inflammasomes. Ginsenosides have also been shown to inhibit caspase-1 and to decrease the expression of $IL-1{\beta}$ and IL-18. Given this body of evidence, the functional relationship between ginsenosides and inflammasome activation provides new insight into the understanding of the molecular mechanisms of ginsenoside-mediated antiinflammatory actions. This relationship also has applications regarding the development of antiinflammatory remedies by ginsenoside-mediated targeting of inflammasomes, which could be used to prevent and treat inflammatory diseases.

Developing of Forest Fire Occurrence Probability Model by Using the Meteorological Characteristics in Korea (기상특성을 이용한 전국 산불발생확률모형 개발)

  • Lee Si Young;Han Sang Yoel;Won Myoung Soo;An Sang Hyun;Lee Myung Bo
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.6 no.4
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    • pp.242-249
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    • 2004
  • This study was conducted to develop a forest fire occurrence model using meteorological characteristics for the practical purpose of forecasting forest fire danger. Forest fire in South Korea is highly influenced by humidity, wind speed, and temperature. To effectively forecast forest fire occurrence, we need to develop a forest fire danger rating model using weather factors associated with forest fire. Forest fore occurrence patterns were investigated statistically to develop a forest fire danger rating index using time series weather data sets collected from 8 meteorological observation centers. The data sets were for 5 years from 1997 through 2001. Development of the forest fire occurrence probability model used a logistic regression function with forest fire occurrence data and meteorological variables. An eight-province probability model by was developed. The meteorological variables that emerged as affective to forest fire occurrence are effective humidity, wind speed, and temperature. A forest fire occurrence danger rating index of through 10 was developed as a function of daily weather index (DWI).

Future Changes of Wildfire Danger Variability and Their Relationship with Land and Atmospheric Interactions over East Asia Using Haines Index (Haines Index를 이용한 동아시아 지역 산불 확산 위험도 변화와 지표-대기 상호관계와의 연관성 연구)

  • Lee, Mina;Hong, Seungbum;Park, Seon Ki
    • Atmosphere
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    • v.23 no.2
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    • pp.131-141
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    • 2013
  • Many studies have related the recent variations of wildfire regime such as the increasing number of occurrances, their patterns and timing changes, and the severity of their extreme cases with global warming. However, there are only a few numbers of wildfire studies to assess how the future wildfire regime will change in the interactions between land and atmosphere with climate change especially over East Asia. This study was performed to estimate the future changing aspect of wildfire danger with global warming, using Haines Index (HI). Calculated from atmospheric instability and dryness, HI is the potential of an existing fire to become a dangerous wildfire. Using the Weather Research and Forecasting (WRF) model, two separated 5-year simulations of current (1995~1999) and far future (2095~2099) were performed and analyzed. Community Climate System Model 3 (CCSM3) model outputs were utilized for the model inputs for the past and future over East Asia; future prediction was driven under the IPCC A1B scenario. The results indicate changes of the wildfire danger regime, showing overall decreasing the wildfire danger in the future but intensified regional deviations between north and south. The overall changes of the wildfire regime seems to stem from atmospheric dryness which is sensitive to soil moisture variation. In some locations, the future wildfire danger overall decreases in summer but increases in winter or fall when the actual fire occurrence are generally peaked especially in South China.

Recognition of Human Typing Pattern Using Neural Network (신경망을 이용한 휴먼 타이핑 패턴 인식)

  • Bae, Jung-Gi;Kim, Byung-Whan;Lee, Sang-Kyu
    • Proceedings of the KIEE Conference
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    • 2006.10c
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    • pp.449-451
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    • 2006
  • With the increasing danger of personal information being exposed, a technique to protect personal information by identifying a non-user in case it is exposed. A study to construct a neural network recognizer for developing a economical and effective user protecting system. For this, time variables regarding user typing patterns from a pattern extraction device. With the variations in the standard deviation for the collected time variables, non-user patterns were generated. The recognition performance increased with the increase in the standard deviation and a higher recognition was achieved at 2.5. Also, five types of training data were generated and the recognition performance was examined as a function of the number of non-user patterns. With the increase in non-suer patterns, the recognition error quantified in the root mean square error (RMSE) was reduced. The smallest RMSE was obtained at the type 5 and 90 non-user patterns. In overall, the type 3 model yielded the highest recognition accuracy Particularly, a perfect recognition of 100% was achieved at 45 non-user patterns.

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Development of Workplace Risk Assessment System Based on AI Video Analysis

  • Jeong-In Park
    • Journal of the Korea Society of Computer and Information
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    • v.29 no.1
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    • pp.151-161
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    • 2024
  • In this paper, we develop 'the Danger Map' of a workplace to identify risk and harmful factors by analyzing images of each process within the manufacturing plant site using artificial intelligence (AI). We proposed a system that automatically derives 'the risk and safety levels' based on the frequency and intensity derived from this Danger Map in accordance with actual field conditions and applies them to similar manufacturing industries. In particular, in the traditional evaluation method of manually evaluating the risk of a workplace using Excel, the risk level for each risk and harmful factor acquired from the video is automatically calculated and evaluated to ensure safety through the system and calculate the safety level, so that the company can take appropriate actions accordingly. and measures were prepared. To automate safety calculation and evaluation, 'Heinrich's law' was used as a model, and a 5X4 point evaluation scale was calculated for risky behavior patterns. To demonstrate this system, we applied it to a casting factory and were able to save 2 people the time and labor required to calculate safety each month.

Oriental Medical Research about Internet Addiction by Study of the Weak Children Symptoms (허약아(虛弱兒) 증상 연구를 통한 인터넷 중독의 한의학적 접근)

  • Kim, Hyun-Ji;Park, Eun-Jung
    • The Journal of Pediatrics of Korean Medicine
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    • v.22 no.2
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    • pp.51-67
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    • 2008
  • Objectives : The purpose of this study is to research the internet addiction and the Weak children. Methods : Total 400 of 5th and 6th grade JeonJu Elementary student children consisted with 203 men, 197 women were chosen for this study. They answered questionnaires of the internet addiction and the Weak children on June 12th, 2008. Results : 75% were general internet user, latent danger user group was 14.7%, high danger user group was 10.3%. The mean of the general weak children was the highest and then the group of children who had Heart, the Lung, the Liver, the Spleen, the Kidney problems were followed. These showed the relationships with living styles, especially eating patterns and parents' concerns about children's internet use. The more serious internet addiction was, the more the weaker children symptoms were answered significantly. The heart weak children symptoms were found in latent-high danger internet user group. Conclusions : In conclusion, the physical and psychological symptoms of the internet addiction children were resulted by the disturbance of Qi and the pathological change of internal organs.

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A Study on the Danger of Flickering Phenomena in Animation Production (애니메이션제작에 있어서 명멸현상의 위험성에 관한 연구)

  • Jeon Hyoung-Do
    • The Journal of the Korea Contents Association
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    • v.6 no.8
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    • pp.57-67
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    • 2006
  • The motion effect of animation can be maximized by using the intended number of frame(flickering phenomena) responding to the viewer's perception in the production processes. But, the high contrast of chroma in a color arrangement can cause very dangerous situation if a particular effect(scheduled number of frame for the intended rapid flickering in a zoom-in scene of the warning light of police car and the traffic light) or a excessive visual stimulus is tried. The danger of flickering phenomena is defined as 'Flash Nervousness Attack Symptom' in medical terminology, which has received wide attention because the damage to the viewers of Pocket Monster was very serious in Japan. Producing a piece of animation work, the quality control of colors is important but the color setting considering the psychological aspects, the danger of repetitive flickering of flashes and patterns in image effect are more serious, so these factors should be checked in the production stages. After investigating the domestic and foreign prescriptions including the guidelines for animation production technique in Japan, a solution to reduce the danger of flickering phenomena of color and light was suggested through statistical comparative analysis with the test results.

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The attribution of the security guard failure and grope for efficient operational measures of security guard through the analysis of failures : propensity eduction of failure-factors of security guard and patterns of danger and injury (경호실패귀인과 실패사례 분석을 통한 효율적인 경호운용방안 모색 : 경호환경의 실패요인과 위해패턴 성향 도출)

  • Kim, Sang Jin
    • Convergence Security Journal
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    • v.18 no.1
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    • pp.143-155
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    • 2018
  • The purpose of this study is to extract the failure attributions to identify the failure factors of the security guards and to derive the risk factor factors through failure cases analysis. Failure attributions were prepared by using semi-structured questionnaires(17) and closed questionnaires(179) starting from the fully open questionnaires(8), and processed through SPSS 21.0 and AMOS 21.O statistical packages. As a result of summarizing the causal relationship between the failure attribution and the failure case (patrol failure pattern factor), In Park Jung-Hee's assassination, lack of experience(2), negative mind(1), lack of work ability(1), lack of experience(2), organizational non-system activeness(2), lack of awareness of mission(1) Failure(2), lack of consciousness(2), and 14 failure patterns were found. Aung-San National Cemetery explosion occurred in eight failure patterns including insecurity(1), negative mind(1), lack of work skills(2), lack of experience(2), individualism(1), There were eight failure patterns in the case of Mr. Yook Young-Su 's sniping, including insincerity(2), negative mind (1), lack of experience(2), lack of awareness of mission(2) and failure to share work(1).

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A study on alcohol use & problem drinking among college students (대학생의 음주와 문제음주에 관한 연구 - 제주도 소재 대학 재학생을 중심으로 -)

  • Lee, Young Ah
    • The Korean Journal of Emergency Medical Services
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    • v.8 no.1
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    • pp.57-70
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    • 2004
  • This is an exploratory study to describe drinking patterns and problem drinking and alcohol-related problem in college students. The major purpose of this study is to describe the prevalence of drinking styles, the quantity of alcohol getting drunken and the describe the frequency of drunkenness in the previous 12months prior to the survey, and to examine the patterns of how various drinking behaviors are different by drinking style. We used the scale for measuring problem drinking NAST(1), AUDIT, indicated that males drank more and more and more frequently, and had episodes of drunkenness and more accepting of drinking than females, the amount of alcohol becoming intoxicated, the frequency and quantity of alcohol consumed in the month, and the frequency of intoxicated were significantly different by drinking styles in both sexes. A problem drinking rate, danger drinker 49.3% dependence drinker 3.5% in ADULT and alcohol dependency 9.7% in NAST(1) It will be necessary to discuss about adequate policy and eucation protrams to be able to curb collegiate's alcohol abuse.

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Implementation of Crime Pattern Analysis Algorithm using Big Data (빅 데이터를 이용한 범죄패턴 분석 알고리즘의 구현)

  • Cha, Gyeong Hyeon;Kim, Kyung Ho;Hwang, Yu Min;Lee, Dong Chang;Kim, Sang Ji;Kim, Jin Young
    • Journal of Satellite, Information and Communications
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    • v.9 no.4
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    • pp.57-62
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    • 2014
  • In this paper, we proposed and implemented a crime pattern analysis algorithm using big data. The proposed algorithm uses crime-related big data collected and published in the supreme prosecutors' office. The algorithm analyzed crime patterns in Seoul city from 2011 to 2013 using the spatial statistics analysis like the standard deviational ellipse and spatial density analysis. Using crime frequency, We calculated the crime probability and danger factors of crime areas, time, date, and places. Through a result we analyzed spatial statistics. As the result of the proposed algorithm, we could grasp differences in crime patterns of Seoul city, and we calculated degree of risk through analysis of crime pattern and danger factor.