• Journal of Microbiology and Biotechnology
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• v.17 no.6
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• pp.993-1001
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• 2007

The technique of serological analysis of antigens by recombinant cDNA expression library (SEREX) uses autologous patient sera as a screening probe to isolate tumor-associated antigens for various tumor types. Isolation of tumor-associated antigens that are specifically reactive with patient sera, but not with normal sera, is important to avoid false-positive and autoimmunogenic antigens for the cancer immunotherapy. Here, we describe a selection methodology to isolate patient sera-specific antigens from a yeast surface-expressed cDNA library constructed from 15 patient lung tissues with non-small cell lung cancer (NSCLC). Several rounds of positive selection using patient sera alone as a screening probe isolated clones exhibiting comparable reactivity with both patient and normal sera. However, the combination of negative selection with allogeneic normal sera to remove antigens reactive with normal sera and subsequent positive selection with patient sera efficiently enriched patient sera-specific antigens. Using the selection methodology described here, we isolated 3 known and 5 unknown proteins, which have not been isolated previously, but and potentially associated with NSCLC.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.30 no.2
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• pp.89-116
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• 2019

The purpose of this study is to investigate the services provided to the patient based on the guidelines and standards due to the importance of the existence and role of the hospital library. The subject of investigation is foreign hospital library. As a result of the related search terms from search engine Google, researcher selected 90 overseas hospital library sites and examined the type of service based on guidelines and standards. As a result of the survey, services were provided mainly for 'basic service' and 'health information resource service' and 'health information resource service' was provided mainly for 'providing and delivering' rather than 'education'. 'Mental and psychological healing services' were found to be insufficient overall. The suggestion for providing hospital library service is as follows. First, it is necessary to provide library name and service that specialize only in patients. Second, it is necessary to expand bibliotherapy service, which is the center of hospital library service, especially providing culture, rehabilitation and entertainment programs, which are mental and mental healing services. Third, it is necessary to arrange human resources of health librarian and volunteer based on librarian.

• International Journal of Advanced Culture Technology
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• v.10 no.4
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• pp.23-244
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• 2022

The Pulpose of this systematic review is aimed to establish the procedure of the injection with saftey and efficiency in the pre-hospital cardiac arrest patient performing the cardiopulmonary resuscitation (CPR), compared with traditional medication administration using Ampoule and medication administration with Prefilled Syringe. Databases were searched for CPR, heart arrest, resuscitation, Pre-filled Syringe, and Ampoule by the electronic data research including Pubmed, EMBASE and Cochran Library of Konyang University Library: 4 articles were selected by three co-authors using EndNote X20 and Covidence (Covidence.org) and were systematically reviewed. The Result of this study, the medication administration using Pre-fillled Syringe improves the safety of patients and Emergency medical workers by reducing the error in administration dose and administering the drug in safe than the medication adminisrtaion using Ampoule, also, contributes to the increment of survival rate of cardiac arrest and severe patients by decreasing the administration time that prevents the delay of medication administration.

• Journal of Computing Science and Engineering
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• v.6 no.2
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• pp.168-177
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• 2012

The search for relevant and actionable information is a key to achieving clinical and research goals in biomedicine. Biomedical information exists in different forms: as text and illustrations in journal articles and other documents, in images stored in databases, and as patients' cases in electronic health records. This paper presents ways to move beyond conventional text-based searching of these resources, by combining text and visual features in search queries and document representation. A combination of techniques and tools from the fields of natural language processing, information retrieval, and content-based image retrieval allows the development of building blocks for advanced information services. Such services enable searching by textual as well as visual queries, and retrieving documents enriched by relevant images, charts, and other illustrations from the journal literature, patient records and image databases.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.30 no.3
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• pp.291-314
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• 2019

In this study, to improve the satisfaction of library users in the hospital and to examine how to activate the library in the future, the satisfaction of library, facilities and environment, staff, service, We conducted a demand survey and searched for the operation plan of the library that satisfied the user. As a result, in order to revitalize the library in the hospital, first, in the case of the collection, it is necessary to expand the number of collections of various topics with the latest contents. Second, it is urgent to expand the number of library staff in the hospital. In addition, it is necessary to improve communication expertise based on medical expertise and ability to respond quickly to user requests. Third, it is necessary to expand the size of library and convenience facilities in the hospital by facilities and environment. Fourth, in case of service, it is necessary to improve service quality and provide various services. Experts should provide subject search service, medical information source service, general health information service (patient and carer) according to the user. Finally, in the case of programs, it is necessary to expand the infrastructure for program operation, to diversify the targets, and to extend the program continuity.

• Women's Health Nursing
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• v.30 no.1
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• pp.26-40
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• 2024

Purpose: This study investigated the scope of patient navigation studies on women's health care for maternal health and noncancerous gynecologic conditions and aimed to report the characteristics of the identified patient navigation programs. Methods: A scoping review was conducted following Arksey and O'Malley's framework. Five electronic databases were searched for relevant studies published in English: PubMed, Embase, Cochrane Library, CINAHL, and PsycInfo. There were no restrictions on the publication date and the search was completed in July 2023. Results: This scoping review included 14 studies, which collectively examined seven patient navigation programs. All selected studies were related to maternal health issues (e.g., perinatal health problems and contraception for birth spacing). Close to two-thirds of the patient navigation services were provided by women (n=9, 64.3%) and half by lay navigators (n=7, 50.0%). The majority incorporated the use of mobile health technologies (n=11, 78.6%). All of the patient navigation programs included in the review coordinated the necessary clinical and social support services to improve women's access to care. Conclusion: Patient navigation appears to be in its nascent phase in the field of maternal health. The results of this study suggest that the implementation of patient navigation services could potentially improve access to care for socially disadvantaged women and families. Furthermore, providing patient navigation services that are specifically tailored to meet women's needs could improve the quality of maternity care.

• Journal of Korean Library and Information Science Society
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• v.39 no.1
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• pp.33-50
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• 2008

The purpose of this study is to provide for efficient health information service which doctors may use for their better medical practice and scientific research. 177 doctors were surveyed from December 3 to December 21th in 2007. This study mentioned activities of information need and use that were evaluated by information gathering methods used, information source, frequency of use, and degree of satisfaction toward library services. Doctors showed that they need information mainly to know the recent research results in their interesting subject field and to treat a patient. Doctors trended to obtain information through internet search because easy access and easy use, accuracy and up to dateness of information use. Doctors trended to seek information mainly through library, but they showed relatively low frequency of library use because they do not know how to use it.

• IMMUNE NETWORK
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• v.2 no.2
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• pp.91-95
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• 2002

Background: In order to characterize human antibodies with specificity for mite allergens at the molecular level, a scFv phage display library was constructed using peripheral blood mononuclear lymphocytes from an asthma patient allergic to mite as Ig gene sources. Methods: Immunoglobulin $V_H$ and V gene fragments were obtained by polymerase chain reaction, and randomly combined in pCANTAB-5E vector. The resulting human scFv phage display library had $3{\times}10^4$ independent clones, and biopanning was performed with house dust mite extracts. Results: Four scFv clones specific for house dust mite extract were isolated. Immunoblot assay showed that our clones reacted to 25 kDa and 50~60 kDa proteins with unknown identity in mite extracts. Sequence analysis indicated that two clones (b7 and c15) are identical, and all clones belong to human $V_H3$ subgroup. On the other hand, light chain usage was different in that two clones (a2 and b7 / c15) belonging to V ${\kappa}4$ subgroup, but a4 used V ${\kappa}1$ light chain gene. Conclusion: Our approach should facilitate provision of useful information on the antibody responses against allergens at the molecular level in humans.

• Journal of the Korean Society for Library and Information Science
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• v.50 no.4
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• pp.55-75
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• 2016

We analyzed the characteristics of the physicians preferred information sources and barriers through in-depth interviews. Information searches for patient treatment were subdivided into deciding patient treatment methods, understanding the latest treatment trends, and preparing presentation materials for conferences. The variables that affected the search behaviors were identified as being background knowledge on the topic, clinical experience, job title, search skills, user training, and familiarity with the library homepage. PubMed was the most preferred choice because of users' familiarity, reliability, and the vastness of information; Google was also used frequently for easy access and fast search result. The accuracy and the recentness of information were the most significant criteria. Easy interface and convenient access were also considered important due to physicians' time constraints. Searching obstacles were divided into difficulty of searching system, unfamiliar term, too vast resources, difficulty to get fulltext articles and complex advanced search features. The results of this study can be utilized as a basis for improving information service of library and curriculum development for physicians.

• Journal of Korean Library and Information Science Society
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• v.49 no.4
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• pp.237-263
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• 2018

In this study, by extracting all relevant types of libraries in the medical field and analyzing their concepts, the research was to clearly define the names and concepts of libraries related to the medical field being mixed and used, to identify types of library, and to draw related legal improvements. The results of the study are as follows: First, the concepts of libraries in the medical field were organized and the types and relationships between libraries in the medical field were summarized. Second, criteria for currently absent hospital libraries are presented based on domestic and overseas research and standards. Third, In order to revitalize libraries related to medical fields in the future, it is necessary to investigate the actual conditions of libraries related to medical fields. Also, It proposed that public hospitals above the hospital level be made mandatory to set up hospital libraries first through national policy and expand services for patients and careers.