• Korean Journal of Veterinary Service
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• v.13 no.1
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• pp.90-95
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• 1990

1) During 5 month(Oct. 1988-Feb. 1989), abortion(11 heads), stillbirth(3 heads), and congenital abnormalities(28 heads) of newborn were occurred in 42 milk cows raised in Cheju island. These cows were diagnosed with Akabane disease by clinical, pathological and serological test. 2) In May and Oct. 1989, 213 tattles at 10 farms were investigated on the actual condition of possessing Akabane antibody. The results was that 210 heads(98.6%) in 213 cattles reacted as positive condition in Akabane antibody. The antibody titer was from 4 to over 256. 3) During some years, the author suppose that the vaccination for Akabane disease will be unnecessary because of higher positive antibody reaction except the newly introduced cattle.

• Korean Journal of Veterinary Service
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• v.17 no.2
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• pp.83-88
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• 1994

The studies were carried out to diagnose of disease chickens that were raised at the chicken farms located in Chung -nam province and evaluated potential of mold growth inhibition of antifungal agent, Mold-X. The diseased 25 chickens that were shown clinical sign such as anorexia, respiratory symptoms, were suspected aspergillosis. The results obtained were summarized as follows ; 1. The diseased thickens were diagnosed aspergillosis according to clinical sign, pathological finding, isolation of etiological agent. 2. The growth of mold was conciderable inhibited by the Mold-X of 300 ppm level.

• Korean Journal of Pharmacognosy
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• v.14 no.4
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• pp.145-148
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• 1983

Angiotensins and bradykinin play important roles in blood pressure regulation and in other physiological and pathological conditions. The present work is aimed to investigate potential antagonists against either angiotensin or bradykinin from plant sources. Each methanol extract of selected 25 plants was solvent fractionated to three fractions. The effects of total of 75 plant samples against the contractions induced by angiotensin I or bradykinin in rat ileum were measured. The results are summarized.

• Korean Journal of Veterinary Service
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• v.22 no.1
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• pp.25-35
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• 1999

The prevalence of canine heartworm(Dirofilaria immitis) infection in 150 mixed-breed dogs(male : 54, female : 96) from February to December 1997 was investigated by using antigen test kit(ICT $GOLD^{TM}$ HW, Synbiotics, USA) based on immunochromatographic assay in Inchon city. Also, gross and histopathological findings of an antigen positive dog were carried out. The results were summarized as follows ; 1. Four dogs were positive from 150 tested dogs(2.7%). They were all more than 2 years old and infection rates in male and outdoor dogs was higher than those in female and indoor, respectively. Species of infected dogs were Pug(2) , German Sheperd(1) and Great-dane (1). 2. Regional infection rates were closely related with housing system in the city. 3. Pathological findings of antigen-positive dog was excessive enlargement, congestion and hemorrhage of lung and D immitis in heart and histologically hemosiderin, hypertrophy of pulmonary alveoli wall and irregular hypertrophy of pulmonary artery inner wall. Microfilaria was observed in pulmonary artery and arteriole, ventricle and splenic artery.

• Korean Journal of Veterinary Research
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• v.60 no.3
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• pp.183-186
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• 2020

This paper describes the development of neurological signs of two prematurely born calves four days after birth. The pathological examination results indicated fibrinopurulent polyserositis, including meningoencephalitis with suppurative bronchopneumonia. Bovine viral diarrhea virus subtype 2a was detected in most of the internal organs, and the bacterial colonies cultured from the samples were identified as Klebsiella (K.) pneumoniae. Molecular analysis via multilocus sequence typing identified a different K. pneumoniae isolate in each calf-type 14 in calf A and type 65 in calf B. This is the first report identifying K. pneumoniae sequence types 14 and 65 in cattle.

• Speech Sciences
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• v.7 no.3
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• pp.285-294
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• 2000

In this paper the acoustic characteristics of pathological voice, which are measured before and after surgical operation, are compared. This experiment is conducted for the purpose of predicting patients' speech after operation. The voices are recorded from the same patients. Jitter, shimmer and other parameters are. computed and their statistical characteristics are compared. Also spectral changes, such as formant frequency shift and spectral slope change, are compared. From the experimental results, it is verified that not only source characteristics but also vocal tract components vary. And this indicates that the modification of source parameters are not enough for the prediction. Also the result indicates that the operation causes change to both the physical shape of vocal folds and the manner of articulation.

• Proceedings of the KIEE Conference
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• 2002.07d
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• pp.2815-2817
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• 2002

Classification method of cancers using cDNA microarrays data was developed using genetic algorithms and neural networks. For gene selection, 2308 genes were ranked using genetic algorithms, and selected by frequency number of selection from 1000 of genetic iterative runs. To calculate fitness values, artificial neural networks are used as classifier. The small, round blue cell tumors (SRBCTs) which is difficult to distinguish via pathological single test was used as test diseases for classification, and the test results showed the 96% of exact classification capability for 25 test samples.

• Animal cells and systems
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• v.12 no.3
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• pp.127-136
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• 2008

Caspase-11 has been known as a dual regulator of cytokine maturation and apoptosis. Although the role of caspase-11 under pathological conditions has been well documented, its physiological role has not been studied much. In the present study, we investigated a possible physiological function of caspase-11 during immune response. In the absence of caspase-11, immunized spleen displayed increased cellularity and abnormal germinal center structure with disrupted microarchitecture. The rate of cell proliferation and apoptosis in the immunized spleen was not changed in the caspase-11-deficient mice. Furthermore, the caspase-11-deficient peritoneal macrophages showed normal phagocytotic activity. However, caspase-11-/-splenocytes and macrophages showed defective migrating capacity. The dysregulation of cell migration did not seem to be mediated by caspase-3, interleukin-$1{\alpha}$ or interleukin-$1{\beta}$ which acts downstream of caspase-11. These results suggest that a direct regulation of immune cell migration by caspase-11 is critical for the formation of germinal center microarchitecture during immune response. However, humoral immunity in the caspase-11-deficient mice was normal, suggesting the formation of germinal center structure is not essential for the affinity maturation of the antibodies.

• PNF and Movement
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• v.5 no.1
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• pp.37-47
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• 2007

Objective : A large proportion of stroke survivors have to deal with problems in gait. Proper evaluation of gait must be undertaken to understand the sensorimotor impairment underlying locomotor disorders post stroke. Methods : The characteristics of gait pattern with post stroke are reviewed in this paper. In particular, temporal distance parameters, kimematics, kinetics, as well as energy cost, EMG are focused. Results : The technology for gait analysis is moving rapidly. The techniques of 3D kinematic and kinetic analysis can provide a detailed biomechanical description of normal and pathological gait. This article reviews gait analysis method and characteristics of post stroke. Finally current method of gait analysis can provide further insight to understand paretic gait and therapeutic direction.

• Animal cells and systems
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• v.16 no.2
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• pp.95-103
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• 2012

Asbestos exposure has been known to contribute to several lung diseases named asbestosis, malignant mesothelioma and lung cancer, but the disease-related molecular and cellular mechanisms are still largely unknown. To examine the effects of asbestos exposure in human bronchial epithelial cells at gene level, the global gene expression profile was analyzed following chrysotile treatment. The microarray results revealed differential gene expression in response to chrysotile treatment. The genes up- and down-regulated by chrysotile were mainly involved in processes including metabolism, signal transduction, transport, development, transcription, immune response, and other functions. The differential gene expression profiles could provide clues that might be used to understand the pathological mechanisms and therapeutic targets involved in chrysotile-related diseases.