• Journal of the Semiconductor & Display Technology
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• v.17 no.3
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• pp.75-84
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• 2018

According to IHS, the overall display market is expected to grow at an average annual rate of 6% from $ 104 billion in 2016, to $ 138 billion in 2021. Among them, the OLED display panel will grow from $ 15 billion to $ 41 billion over the same period, forecasting a high annual growth rate of 22%. However, the refraction index, light leakage, bubble generation, adhesion deterioration, peeling phenomenon, moisture resistance, light transmittance, low turbidity. OCA (optically clear adhesive), which solves problems such as improving the resistance of the conductive film, is largely dependent on imported products. In addition, in 2016, the world market is worth KRW4.3 trillion, and the adhesive market has a large market effect. In this study, we tried to analyze the technical competitiveness of patent and thesis by classifying OCA (optically clear adhesive, optical adhesive) for display panel by curing method. As a result of the study, the amount of patents and papers in Korea was found to be superior to other competitors, but the quality level was low. In particular, it was found that the achievements of the papers in the hot melt field are lacking and the government should expand its support.

• Archives of Plastic Surgery
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• v.43 no.2
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• pp.145-152
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• 2016

Background Innovation has molded the current landscape of plastic surgery. However, documentation of this process only exists scattered throughout the literature as individual articles. The few attempts made to profile innovation in plastic surgery have been narrative, and therefore qualitative and inherently biased. Through the implementation of a novel innovation metric, this work aims to identify and characterise the most prevalent innovations in plastic surgery over the last 50 years. Methods Patents and publications related to plastic surgery (1960 to 2010) were retrieved from patent and MEDLINE databases, respectively. The most active patent codes were identified and grouped into technology areas, which were subsequently plotted graphically against publication data. Expert-derived technologies outside of the top performing patents areas were additionally explored. Results Between 1960 and 2010, 4,651 patents and 43,118 publications related to plastic surgery were identified. The most active patent codes were grouped under reconstructive prostheses, implants, instruments, non-invasive techniques, and tissue engineering. Of these areas and other expert-derived technologies, those currently undergoing growth include surgical instruments, implants, non-invasive practices, transplantation and breast surgery. Innovations related to microvascular surgery, liposuction, tissue engineering, lasers and prostheses have all plateaued. Conclusions The application of a novel metric for evaluating innovation quantitatively outlines the natural history of technologies fundamental to the evolution of plastic surgery. Analysis of current innovation trends provides some insight into which technology domains are the most active.

• Journal of Korea Technology Innovation Society
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• v.15 no.1
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• pp.185-202
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• 2012

This study analyzed the achievement characteristics of 21st Century Frontier R&D Program depending on the subject of study, type, period in order to provide necessary data required during planning and execution of the large scale R&D projects. 21st Century Frontier R&D Program is a representative national R&D project that has been supported for a decade. The research achievements were analyzed for researchers who participated in each four projects completed in 2010 and 2011 among 16 R&D projects of 21st Century Frontier R&D Program promoted by Ministry of Education, Science and Technology. The research is summarized as follows. First, the achievements varied depending on the main agent such as universities, R&D institutions, and industries. The achievement of universities includes significantly larger publications than those of R&D institutions and industries. Second, the rate of overseas patent application and registration were higher in industries significantly than those in other research agents. Third, the achievements differed depending on research type such as basic, applied, and development researches, and the development researches exhibited significantly higher achievements in domestic patent application and registration, overseas patent application, and technology transfer. Fourth, in terms of the research period, long-term projects show significantly larger number of domestic patent applications than those from short-term projects. Fifth, when achievements like the publication and overseas patent application were classified in such fields as bio, nano, and energy environment R&D, bio and nano fields showed higher achievement than the energy environment field. This research could empirically confirm that the achievement characteristics of large scale and long-term government support R&D projects vary for each research properties.

• International Journal of Knowledge Content Development & Technology
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• v.5 no.1
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• pp.69-88
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• 2015

This study seeks to present an option for including a variety of information resources in a reference linking service system. Discussion on reference linking service in journals began in 1999 and applied to real systems, but linking to research papers and patent registers has more recently emerged. This study further suggests that system construction include various information resources such as books and dissertations. This paper also presents principles and prerequisites that should be considered essential when building such systems, including expansion of resources and media formats, development of identifiers on every sort of information resource, linking methods to existing DB, publication revolution and managing copyright-holders, use and improvement of OPACs, and building perfect authority DB.

• Journal of Korea Technology Innovation Society
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• v.12 no.3
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• pp.638-661
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• 2009

With the advance to the knowledge-based economy, science and technology (S&T) has been recognized as key factor in a nation's competitiveness. To cope with this kind of new trend Korean government has tried to increase the R&D investment and to streamline acts and regulations concerning national R&D activities. Korea's total R&D expenditure for the year 2007 amounted to about 31.3 trillion won including government R&D of 8.9trillion won. With these efforts the capacity of Korea S&T has made great strides recently. Korea was ranked world's top 7 in R&D investment, top 12 in S&T paper publication and top 4 in patent application. Korean government enacted several pieces of legislation concerning S&T : the "Technology Transfer Promotion Act (1999)"; the "Framework Act on Science and Technology (2000)"; and the "Presidential Regulation for Managing the Government R&D Programs (2001)." In addition, the government has put a lot of effort into promoting the commercialization of technologies developed in public sector and improving the infrastructure of technology transfer and commercialization. However in spite of these various efforts, the technologies obtained from the public sector have not been transferred to the industry properly. Only 24.2% of technologies developed in the public for the year 2005 were transferred to industry. The royalty revenues of the public for the year 2005 was 1.5% of their total R&D expenditure. It shows only a third of the percentage of royalty revenues for the public sector in the U.S.A. and a second of Europe. There are many obstacles of public technology transfer such as immaturity of technology market, lack of licensing experience, and inadequacy of legal system and government policy. In this study I compared the Korean legislative system of patent management of government R&D outputs with the American system, derived problems from Korean system, and suggested proper alternatives.

• Natural Product Sciences
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• v.27 no.3
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• pp.141-150
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• 2021

This short review on the chemistry, pharmacological properties and patents of obovatol and obovatal from Magnolia obovata is the first publication. Pharmacological properties are focused on anti-cancer, anti-inflammatory, anti-platelet and neuroprotective activities. Obovatol and obovatal were first isolated from the leaves of M. obovata. Also reported in the bark and fruits of M. obovata, obovatol and obovatal are neolignans i.e., biphenolic compounds bearing a C-O coupling. Other classes of compounds isolated and identified from M. obovata include sesquiterpene-neolignans, dineolignans, trineolignan, lignans, dilignans, phenylpropanoids, phenylethanoid glycosides, flavonoids, phenolic acids, alkaloids, sesquiterpenes, ketone and sterols. The anti-cancer properties of obovatol and obovatal involve apoptosis, inhibition of the growth, migration and invasion of cancer cell lines. However, obovatol displays cytotoxicity against cancer cells but not obovatal. Similarly, anti-inflammatory, anti-platelet, neuroprotective, anxiolytic and other pharmacological activities were only observed in obovatol. The disparity in pharmacological properties of obovatol and obovatal may be attributed to the -CHO group present in obovatal but absent in obovatol. From 2007 to 2013, eight patents were published on obovatol with one mentioning obovatal. They were all published at the U.S. Patent and Trademark Office by scientists of the Korea Research Institute of Bioscience and Biotechnology (KRIBB) as inventors and assignee, respectively. Some future research and prospects are suggested.

• Applied Chemistry for Engineering
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• v.28 no.4
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• pp.410-419
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• 2017

Since the beginning of the water shortage by disasters such as global warming, environmental pollution, and drought, development of original technology and studies have been undergone to increase availability of water resources. Among them the water treatment separation membrane technology is an environmentally friendly process that does not use chemicals and shows better water quality improvement effect than conventional physicochemical and biological processes. The water treatment membrane can be applied to various fields such as waste water treatment, water purification treatment, seawater desalination, ion exchange process, ultrapure water production, organic solvent separation and water treatment technology, and it tends to expand the range of application. In the core technology of water treatment membrane, researches are being actively carried out to develop a separation membrane of better performance by controlling the pore size to adjust the separation performance. In this review, we summarized the frequency of announcement by country and organization through the technological competitiveness evaluation of patents and papers of the water separation membrane. Also, we evaluated the results from membrane research for waste water treatment, water purification treatment, seawater desalination, ion exchange process and present the future direction of research.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.455-460
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• 2020

The governments of Korea, China, and Japan have operated comprehensive research institutes for railway technologies. Korea Railroad Research Institute (KRRI), China Academy of Railway Sciences Corporation Limited (CARS), and Railway Technical Research Institute (RTRI) are representatives of comprehensive railway research institutes in each country. KRRI was found to be the most advanced in the quantitative competitiveness of patents. In terms of qualitative competitiveness, KRRI has strength in civil engineering, whereas RTRI has strength in electricity. KRRI was found to have the greatest efforts in securing competitiveness in overseas property rights. By comparing the publication of papers, CARS published the most papers. On the other hand, from 2015, KRRI showed an upward trend and published the most papers. By examining the impact of the papers by the citation, KRRI was found to have higher competitiveness than the other two institutions. In the future, it will be necessary to perform big data analysis on patents and papers of the three organizations, derive the key research areas and promising technology areas for each institute, and establish a mid-to-long-term development plan for railway technology based on scientific evidence.

• The Journal of Internal Korean Medicine
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• v.44 no.3
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• pp.485-505
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• 2023

Objective: The purpose of this study is to assess the effectiveness and safety of using Taeksa-tang for dyslipidemia through a systematic review and meta-analysis of randomized controlled trials (RCTs). Methods: The search was conducted using keywords such as "dyslipidemia", "hyperlipidemia", "taeksa tang", "zexie tang", and "takusha to" in 12 databases (Pubmed, Cochrane, Embase, ScienceDirect, CNKI, Wanfang, CiNii, RISS, KISS, ScienceON, OASIS, and DBpia) on April 13, 2023. There were no limits on the publication period and language. Cochrane's risk of bias (RoB) was used to evaluate the quality of the studies. A meta-analysis was conducted according to the outcome measurements such as total effective rate (TER), total cholesterol (TC), triglyceride (TG), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), and adverse effects, using the Review Manager web. Results: A total of 9 RCTs were selected. In evaluating the RoB, 2 studies mentioning the random sequence generation, 1 study conducting double blindness, and 8 studies without missing values were evaluated as low risk, while 1 study without mentioning the random sequence generation was evaluated as high risk. All other parts were evaluated as unclear risk. The treatment group (Taeksa-tang or Taeksa-tang-gagam) showed more statistically significant effects compared to the control group (Western medicine or Chinese patent medicine) in TER (RR : 1.24, 95% CI 1.15 to 1.34, P<0.00001), TC (MD : -1.12, 95% CI -1.68 to -0.56, P<0.0001), TG (MD : -1.08, 95% CI -1.65 to -0.51, P=0.0002), HDL-C (MD : 0.63, 95% CI 0.34 to 0.93, P<0.0001), LDL-C (MD : -0.81, 95% CI -1.10 to -0.53, P<0.00001). In addition, the treatment group showed lower adverse effects compared to the control group (RR : 0.30, 95% CI 0.12 to 0.74, P=0.008). Conclusion: This study suggests that Taeksa-tang is effective and safe to use for treating dyslipidemia. However, due to the low quality of the included studies, more clinical studies need to be conducted in the future to increase the possibility of clinical use.