• The Journal of Internal Korean Medicine
• /
• v.37 no.5
• /
• pp.733-740
• /
• 2016

Objective: To evaluate the effects of integrative treatment with conventional and Korean medicine on cerebral infarction due to presumed paradoxical embolism through a patent foramen ovale. Methods: We applied acupuncture, herbal medication, western medication, and physical therapy routinely every day and applied fluid therapy provided as needed. The NIHSS, K-MBI, MRS, MMT, and MMSE-K score were determined to assess any improvement in symptoms. Results: Scores appeared to be improved for the NIHSS (9 to 5), K-MBI (94 to 100), MRS (2 to 1), MMT (2+, 4 to 4, 4), MMSE-K (24 to 26). No side effects were observed during the treatment. Conclusions: This study demonstrates that integrative treatment with conventional and Korean medicine may be an effective option for treating cerebral infarction due to a presumed paradoxical embolism through a patent foramen ovale.

• Korean Journal of Pharmacognosy
• /
• v.38 no.3 s.150
• /
• pp.234-238
• /
• 2007

Hyo Shim Dan Hwan (孝心丹丸) is a Chinese patent medicine which is used for neuralgia and palsy in Korea. This medicine consists of 15 kinds of powdered crude drugs. For the identification of individual ingredients in such powdery mixtures, microscopic method may advantageously be used, as it requires only small amount of specimens. In this study, the effectiveness of this method is exemplified by the identification of the ingredients in Hyo Shim Dan Hwan, which contains 15 powered crude drug ingredients.

• Korean Journal of Pharmacognosy
• /
• v.22 no.2
• /
• pp.128-133
• /
• 1991

Sengwe Dan(生胃丹) is a Chinese patent medicine, which is used for stomachic disorder, heavy drinking, voracious eating, acute and chronic indigestion, diarrhea, nausea and vomiting in Korea. In the future, the demand for the drug is likely to increase, as the number of aged people increases. This medicine is in the large of pills consisting 19 kinds of powdered crude drugs. For the identification of individual ingredients in such powdery mixtures, microscopic method may advantageously be used as it requires only a small amount of specimens. In this paper, the effectiveness of this method is exemplified by the identification of the ingredients in Seng-We-Dan which contains 19 powdered crude drug ingredients.

• Korean Journal of Pharmacognosy
• /
• v.29 no.3
• /
• pp.159-162
• /
• 1998

'Hae Dong Gye Meong Hwan' is a Chinese patent medicine, which is used as a cough remedy or an expectorant, for asthma, bronchitis, and so on in Korea. This powdery medicine consist of 14 kinds of crude drugs. For the identification of individual ingredients in the preparation, microscopic method may advantageously be used as it requires only a small amount of specimens. In this paper, the effectiveness of this method is exemplified by the identification of the ingredients.

• Korean Journal of Veterinary Research
• /
• v.47 no.4
• /
• pp.461-467
• /
• 2007

A 6-year-old female Maltese dog (body weight 2.0 kg) was referred to the Veterinary Teaching Hospital, Kangwon National University with primary complaints including exercise intolerance and heart murmur. Based on clinical and diagnostic findings including grade V/VI left basal continuous murmur, bounding femoral pulsation, left ventricular enlargement pattern in electrocardiogram, cardiomegaly with aortic bulging on the thoracic radiography, and shunt flow between aorta and pulmonary artery on the echocardiography, the dog was diagnosed as the left-to-right patent ductus arteriosus. The patent ductus arteriosus was successfully treated by lodging a single embolization coil with transjugular approach.

• Korean Journal of Pharmacognosy
• /
• v.29 no.1
• /
• pp.40-43
• /
• 1998

'Jeong Wi Dan' is Chinese patent medicine. which is used for stomachic disorder, gastric and duodenal ulcer. This medicine is in the large of pills consisting 14 kinds of powdered crude drugs. For the identification of individual ingredients in such powdery mixtures, microscopic method may advantageously be used as it requires only a small amount of specimens. In this paper, effective of this method will be exemplified by the identification of the ingredients in Jeong We Dan which contains 14 powdered crude drug ingredients.

• The Korea Journal of Herbology
• /
• v.37 no.6
• /
• pp.45-52
• /
• 2022

Objective : In this study, we conducted to analysis the patents about Korean medicine based treatment technology for pet. Methods : We collected the Korean, Japan, USA, China, EU and PCT patent for the Korean medicine-based treatment technology for pet using WIPSON data base registered by October 4, 2020 were selected. Results : Patents for the development of pet Korean medicine-based treatment technology have been constantly applied since the mid-2000s, starting in 1990, with a total of 84 applications. The number of patent applications filed in Korea was the largest, after Japan and China. The detailed composition of the applications reported until now is pharmaceutical compositions for the treatment of pet were the most applied with 39%(33 cases), followed by feed used as stocks for pet at 36%(30 cases). According to the patent application rate by disease, most of applications rate composed to be associated with immunity in 2009 to 2013 with 40% of applications. In 2014 to 2018 43% of patent applications are associated with gastrointestinal/digestive system. In this regard, multiple applications were filed in the order of immunity, digestive system, obesity and urinary system. Conclusion : This study analyzed the trend of 84 patents about Korean medicine-based treatment technology for pet to date to establish the basis for future research and development. There were many applications related to immunity from 2009 to 2013, and since then, related to digestive disease from 2014 to 2018.

• Journal of Oriental Neuropsychiatry
• /
• v.33 no.3
• /
• pp.287-299
• /
• 2022

Objectives: The purpose of this study was to analyze the trend of natural product-based products for sleep improvement in Korean patents, to enhance the development and application of natural-products for sleep disorder in terms of Korean medicine. Methods: We collected patent data using the KIPRIS database and ScienceON database. Two authors independently screened patents that potentially met the criteria, and assessed full texts of screened patents for eligibility. Included patents were analyzed, quantitatively as well as qualitatively. Results: A total of 60 patents were selected 2008-July 2022. The number of patents have been on the rise since 2017, and reached 12 in 2018. Companies have registered the most patents, followed by the Industry-University Cooperation Foundation. Zizyphi semen (n=6), Lactuca sativa L. (n=5), Valeriana fauriei/officinalis (n=4), Poria cocos (n=4) were frequently used herbs among 60 patents. Twenty-one patents (35%) included medicinal herbs with sleep improving effects. Among 60 patents, alcohol extraction (70%) was mostly used, followed by water immersion (50%), and hot water extraction (48.3%). Conclusions: Analysis results showed that various Korean medicine herbs, are being used for natural-products for sleep disorder. The results will be helpful towards inventing new patents using Korean medicine, developing natural product extracts for sleep improvement, and extending the range of these products in clinical use.

• The Journal of the Korea Contents Association
• /
• v.18 no.3
• /
• pp.62-69
• /
• 2018

This study investigate the patent trend of natural feed additives for avian influenza prevention and immunity enhancement. The search scope is Korean and Chinese patents published before December 31, 2017. As a result, I found 53 Korean patents and 105 Chinese patents. Korea and China has increased the number of patent applications since late 2000. In particular, China filed the most patent applications in 2016. Both Korea and China, the oriental medicine materials were mainly used in patent claims. Korea has many patent applications that are submitted by universities, research institutes and bio companies, but China has a high proportion of individual patent applicants.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2018.10a
• /
• pp.39-39
• /
• 2018

The Schizandra chinensis (Korean name : omija) is a fruit native to northeast Asia that is cultivated in South Korea and China. Using 1,938 valid patents of 6 group countries, we analyzed the patent trend based on year, countries, applicants, and technology. The technologies are categorized the 10 sub-technologies such as medicine, quasi-drugs, food, feed, cosmetics, cultivation, genome, manufacture, preprocessing, and etc. The technology level and competitiveness are analyzed using patent index such as cites per patent, patent impact index, patent family size and technology strength. In Korea, patent number rapidly increasing and individual technical level is lower than other countries. However, overall technical competitiveness is estimated high due to multiple patents. We suggest that cosmetics and cultivation fields are most likely to be developed in future omiza technology development in Korea. Our study will provides to the information of technical trend to support performing of new projects for omija plant.