• 한국대기환경학회지
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• 제28권6호
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• pp.644-655
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• 2012

As soon as a new air filter is applied to an air purification process, the filter gets loaded with dust particles. Thus, the study on the particle loading characteristics of air filter is very essential in order to understand the real filtration phenomena during filter use. In this study, we investigated the effect of particle and filter charge on the particle loading property of air filter. Charged filter and uncharged filter prepared by discharging the charged filter by isopropyl alcohol were used as test samples, and three types of particle having different charge states were supplied to filters tested. For neutralized particles there was a big difference in areal mass loading rates between charged and uncharged filters due to the very small amount of particle charge, on the other hand the difference was diminished for atomized particle and finally almost vanished for corona charged particles. The pressure drop of filter loaded with corona charged particles was only half of those for neutralized and atomized particles at the same areal mass loading because of the porous structure of particle deposit formed on filter fibers, caused by the space charge effect between particles.

• International Journal of Aeronautical and Space Sciences
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• 제12권3호
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• pp.296-304
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• 2011

In order to design a shear coaxial injector of solid particles with water, basic experiments on a particle laden jet are necessary. The purpose of the present study is to understand the effect of particle loading ratio on the particle spray characteristics (i.e. spreading angle, distribution of particle number density, velocity profiles, and particle developing region length). Hydro-reactive Al2O3 particles with a primary particle diameter of 35~50 ${\mu}m$ are used in this experiment. An automated particle feeder was designed to supply constant particle mass flowrates. Air is used as the carrier gas. To determine the air velocity at the orifice exit, tracers (aluminum oxide, 0.5~2 ${\mu}m$ primary diameter) are also supplied by a tracer feeder. A plain orifice type injector with 3 mm diameter, and 20 mm length was adopted. Particle image velocimetry is used to measure the mean and fluctuating velocity components along the axial and radial directions.

• Journal of Pharmaceutical Investigation
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• 제28권4호
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• pp.249-255
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• 1998

Solid Lipid Nanoparticle(SLN), one of the colloidal carrier systems, has many advantages such as good biocompatibility, low toxicity and stability. In this paper, the effects of drug lipophilicity and surfactant on the drug loading capacity, particle size and drug release profile were examined. SLNs were prepared by homogenization of melted lipid dispersed in an aqueous surfactant solution. Ketoprofen, ibuprofen and pranoprofen were used as model drugs and tweens and poloxamers were tested for the effect of surfactant. Mean particle size of prepared SLNs was ranged from 100 to 150nm. The drug loading capacity was improved with the most lipophilic drug and low concentration of surfactant. Particle size and polydispersity of SLNs were changed according to the used lipid and surfactant. The rates of drug release were controlled by the loading drug and surfactant concentration. SLN system with effective drug loading efficiency and proper particle size for the intravenous or oral formulation can be prepared by selecting optimum drug and surfactant.

• 대한기계학회논문집
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• 제15권1호
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• pp.292-298
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• 1991

본 연구에서는 입자질량고적재(high particle mass loading)의 경우가 전혀 고려되지 않았으며, 이것은 물론 임팩터가 사용되는 대부분의 경우, 즉, 대기중입자를 포집하는 경우에 입자의 적재량이 미소하기 때문이다. 그러나 임팩터 혹은 이와 유 사한 기능을 하는 장치의 응용은 매우 광범위하여 이중에는, OWG(optical wave guide) 제작이나 페인트 스프레이(paint spray) 또 입자공급장치에서 큰 입자를 걸러 낼 때와 같이, 입자의 적재량이 큰 경우도 적지 않다. 이러한 입자질량 고적재인 경우에는 입자운동이 기체유동장을 변화시키며 이에 따라 입자운동 자체도 변화되어진다. 본 연구에서는 이러한 관계를 분석하여 입자질량의 적재량정도가 입자의 포집효율에 미치 는 영향을 밝혀내었다.

• Journal of Pharmaceutical Investigation
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• 제31권4호
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• pp.241-256
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• 2001

Alginate microspheres, containing fluorescein isothiocyanate-bovine serum albumin (FITC-BSA) or green fluorescent protein (GFP) were prepared and used as a model drug to develop the oral vaccine delivery system. The alginate microspheres were coated with poly-L-lysine or chitosan. Two methods, w/o-emulsion and spray, were used to prepare alginate microspheres. To optimize preparation conditions, effects of several factors on the particle size and particle morphology of microsphere, and loading efficiency of model antigen were investigated. In both preparation methods, the particle size and the loading efficiency were enhanced when the concentration of sodium alginate increased. In the w/o-emulsion preparation method, as the concentration of Span 80 was increased from 0.5% to 2%, the particle size was decreased, but the loading efficiency was increased. The higher the emulsification speed was, the smaller the particle size and loading efficiency were. The concentration of calcium chloride did not show any effect on the particle size and loading efficiency. In the spray preparation method, the particle size was increased as the nozzle pressure $(from\;1\;kgf/m^2\;to\;3\;kgf/m^2)$ and spray rate was raised. Increasing calcium chloride concentration (<7%) decreased the particle size, in contrast to no effect of calcium chloride concentration on the w/o-emulsion preparation method. Alginate microspheres prepared by two methods were different in the particle size and loading efficiency, the particle size of microspheres prepared by the spray method was about $2-6\;{\mu}m$, larger than that prepared by the w/o emulsion method $(about\;2{\mu}m)$, and the loading efficiency was also higher with spray method. Furthermore, drying process for the microspheres prepared by the spray was simpler and easier, compared with the w/o emulsion preparation. Therefore, the spray method was chosen to prepare alginate microspheres for further experiments. Release pattern of FITC-BSA in alginate microspheres was evaluated in simulated intestinal fluid and PBS (phosphate buffered saline). Dissolution rate of FITC-BSA from alginate/chitosan microsphere was lower than that from alginate microsphere and alginate/poly-L-lysine microsphere. By confocal laser scanning microscope, it was revealed that alginate/FITC-poly-L-lysine microspheres were present in close apposition epithelium of the Peyer's patches of rabbits following inoculation into lumen of intestine, which proved that microspheres could be taken up by Peyer's patch. In conclusion, it is suggested that alginate microsphere prepared by spray method, showing a particle size of & $10\;{\mu}m$ and a high loading efficiency, can be used as a model drug for the development of oral vaccine delivery system.

• Structural Engineering and Mechanics
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• 제86권5호
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• pp.607-619
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• 2023

This study, it was tried to evaluate the asphalt behavior under tensile loading conditions through indirect Brazilian and direct tensile tests, experimentally and numerically. This paper is important from two points of view. The first one, a new test method was developed for the determination of the direct tensile strength of asphalt and its difference was obtained from the indirect test method. The second one, the effects of particle size and loading rate have been cleared on the tensile fracture mechanism. The experimental direct tensile strength of the asphalt specimens was measured in the laboratory using the compression-to-tensile load converting (CTLC) device. Some special types of asphalt specimens were prepared in the form of slabs with a central hole. The CTLC device is then equipped with this specimen and placed in the universal testing machine. Then, the direct tensile strength of asphalt specimens with different sizes of ingredients can be measured at different loading rates in the laboratory. The particle flow code (PFC) was used to numerically simulate the direct tensile strength test of asphalt samples. This numerical modeling technique is based on the versatile discrete element method (DEM). Three different particle diameters were chosen and were tested under three different loading rates. The results show that when the loading rate was 0.016 mm/sec, two tensile cracks were initiated from the left and right of the hole and propagated perpendicular to the loading axis till coalescence to the model boundary. When the loading rate was 0.032 mm/sec, two tensile cracks were initiated from the left and right of the hole and propagated perpendicular to the loading axis. The branching occurs in these cracks. This shows that the crack propagation is under quasi-static conditions. When the loading rate was 0.064 mm/sec, mixed tensile and shear cracks were initiated below the loading walls and branching occurred in these cracks. This shows that the crack propagation is under dynamic conditions. The loading rate increases and the tensile strength increases. Because all defects mobilized under a low loading rate and this led to decreasing the tensile strength. The experimental results for the direct tensile strengths of asphalt specimens of different ingredients were in good accordance with their corresponding results approximated by DEM software.

• 대한기계학회논문집
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• 제15권1호
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• pp.252-261
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• 1991

본 연구에서는 2상 횡분류의 평균 유동특성을 비교적 정확히 예측할 수 있는 방법을 제시하는데 있다. 이를 위하여 2상 기체 분류속에 유입되는 자유흐름의 질량 유입을 Keffer와 Baines의 유입함수를 이용하기로 하며, 입자와 기체분류사이의 궤적 이탈을 고려하기로 한다. 이런 모델을 이용하여 2상 횡분류의 분출초기의 입자와 기 체분류의 속도비(particle to gas velocity ratio at the jet exit)가 유동에 미치는 영향을 알아보고자 한다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집A
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• pp.377-382
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• 2001

Mechanical behavior and electrical resistance change of CPDP (carbon particle dispersed plastic) composite consisting of epoxy resin and conductive carbon particle were investigated under monotonic loading and repeated loading-unloading. The electrical resistance almost linearly increased with increasing strain during loading and the residual electrical resistance was observed even after removing load. The value of the residual electrical resistance was dependent on the maximum strain under the applied stress. This result suggests that the estimation of maximum strain (i.e., damage) is possible by the measuring electrical resistance of composite. The behavior of electrical resistance change during and after loading was discussed on the basis of the results of microscopic deformation and fracture observation. Moreover, the relationship between the volume fraction of carbon particle and the electrical resistivity of CPDP was investigated in relation to the percolation theory. Simulation model of percolation structure was established by Monte Carlo method and the simulation result was compared to the experimental results. The electrical resistance change under applied loading was analyzed quantitatively using the percolation equation and a simple model for the critical volume fraction of carbon particle as a function of the mechanical stress. It was revealed that the prediction was in good agreement with the experimental result except in the region near the failure of material.

• Geomechanics and Engineering
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• 제14권1호
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• pp.1-8
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• 2018

This paper presents an investigation of the liquefaction characteristics and particle crushing of isotropically consolidated silica sand specimens at a wide range of confining pressures varying from 0.1 MPa to 5 MPa during undrained cyclic shearing. Different failure patterns of silica sand specimens subjected to undrained cyclic loading were seen at low and high pressures. The sudden change points with regard to the increasing double amplitude of axial strain with cycle number were identified, regardless of confining pressure. A higher cyclic stress ratio caused the specimen to liquefy at a relatively smaller cycle number, conversely producing a larger relative breakage $B_r$. The rise in confining pressure also resulted in the increasing relative breakage. At a specific cyclic stress ratio, the relative breakage and plastic work increased with the rise in the cyclic loading. Less particle crushing and plastic work consumption was observed for tests terminated after one cyclic loading. Majority of the particle crushing was produced and majority of the plastic work was consumed after the specimen passed through the phase transformation point and until reaching the failure state. The large amount of particle crushing resulted from the high-level strain induced by particle transformation and rotation.

• Korean Chemical Engineering Research
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• 제46권5호
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• pp.983-987
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• 2008

IGCC 파일럿 플랜트의 집진시스템을 최적 설계하기 위하여 수치해석을 수행하였다. 서로 다른 가스 유입 방식이 집진용기 내부의 유체 유동장과 입자 거동에 미치는 영향을 분석하였다. 필터 표면에 전달되는 입자의 부하율은 분진입자가 혼합된 가스가 내부에 차단관이 설치된 집진용기의 외벽에 접하게 설치된 접선 유입구를 따라 집진용기 내로 유입되는 경우 아주 낮았으며, 입자크기가 클수록 입자부하율은 급격히 감소하였다. 이에 반하여, 가스 유동이 집진용기의 필터지지판 중앙에 수직하게 설치된 수직 유입구를 통하여 집진용기 내로 유입되는 경우, 필터 표면으로의 입자 부하율이 아주 높았으며, 입자크기 증가에 따른 입자부하율의 감소는 접선 유입 방식에 비하여 크지 않았다.