Objectives : Mucosa-associated lymphoid tissue(MALT) lymphoma of the head and neck region is relatively rare, but it has variable clinical and biological characteristics. Although there were few studies on this topic, there is still controversy regarding the best treatment. The authors retrospectively investigated the clinical courses and treatment results in 10 patients presenting with MALT-lymphoma in head and neck region except ocular adnexa. Material and Methods : Ten patients with a histologically verified diagnosis of the extranodal marginal zone B cell lymphoma arising in thyroid glands(3), larynx(3), oral cavity(2), oropharynx(1), salivary glands(1) were analyzed. Results : Four patients were allocated to stage IE and another six patients to stage IIE according to the Ann Arbor staging system. Treatment consisted of local therapy(surgical resection and/or radiotherapy) in four patients and systemic chemotherapy with/without local therapy in six patients. Complete remission and partial remission were achieved in seven patients(70%) and two patients(20%), respectively. No recurrence or mortality was observed with a mean follow-up of 40.5 months. Conclusion : Patients with MALT-lymphomas of the head and neck region were potentially treated by local modality in localized disease state. However systemic chemotherapy was also effective even in localized disease state and was well tolerated by patients. And strict staging and close long-term monitoring were recommended considering its indolent progression.
The Ogcheon Au-Ag deposit consists of two quartz veins that fill the NE or NW-trending fissures in the metasedimentary rocks of unknown age. The quartz veins occur mainly in the massive type with partially breccia and cavity. They can be found along the strike for about minimum 50 m and varied in thickness from 0.1 to 0.3 m. The mineralogy of quartz veins from the Ogcheon deposit is mainly composed of hydrothermal alteration minerals such as pyrite, quartz, sericite, chlorite, clay minerals and sulfides including pyrite, pyrrhotite, arsenopyrite, sphalerite, chalcopyrite and galena. Fluid inclusion data from quartz indicate that homogenization temperatures and salinity of mineralization range from 184 to $362^{\circ}C$ and from 0.0 to 6.6 wt.% eq. NaCl, respectively. These suggest that ore forming fluids were progressively cooled and diluted from mixing with meteoric water. Sulfur(${\delta}^{34}S$: 0.4~8.4‰) isotope composition indicates that ore sulfur was derived from mainly magmatic source although there is a partial derivation from the host rocks. The calculated oxygen(${\delta}^{18}O$: 4.9~12.1‰) and hydrogen(${\delta}D$: -92~-74‰) isotope compositions suggest that magmatic and meteoric ore fluids were equally important for the formation of the Ogcheon deposit and then overlapped to some degree with another type of meteoric water during mineralization.
Soft tissue sarcoma of the head and neck is not frequent neoplasm, accounting for less than 1% of all malignant neoplasm in the region. The histological varieties include osteogenic sarcoma, malignant fibrous histiocytoma, rhabdomyosarcoma, fibrosarcoma, tenosynovial sarcoma, angiosarcoma and chondrosarcoma. Rhabdomyosarcomas of the head and neck usually occur in children under the age of 10 years (over 70%) and rarely develop in adults over the age of 20 years. The prevalent sites of involvement include the orbit, nasal cavity, external ear, paranasal sinus and soft tissue of mouth and the primary location of tumor is considered to be one of the important prognostic factors. Before the 1960s, when surgical resection was the only method of treatment, the 5-year survival rate was less than 20%, but recently it has been greatly improved by the multimodality treatment, combining surgery with chemotherapy and radiation therapy. Here we treated a rhabdomyosarcoma woman with three cycles of high dose chemotherapy followed by radiation therapy. After the, completion of preoperative treatments, successful result of more than partial response was achieved. Three months later total maxillectomy and radical neck dissection was performed. There was no evidence of tumor infiltration in the resected tumor and regional lymphnodes but metastasized tumor cells in cervical lymphnodes were detected. Tumor cell infiltration was also found on the bone marrow biopsy to evaluate the pancytopenia which occurred during postoperative recovery. Two months later she died of secondary bone marrow failure. We think that this multimodality treatment combining pre-operative chemotherapy, radiotherapy and surgery might play an important role in curative resection and eyeball preservation in patients with rhabdomyosarcoma involving the eyeball.
Park, Hye Sun;Kwak, Hyun Jung;Park, Dong Won;Koo, Tai Yeon;Kim, Hye Young;Park, So Yeon;Ahn, Seong Eun;Kim, Sang-Heon;Kim, Tae Hyung;Sohn, Jang Won;Chung, Won Sang;Yoon, Ho Joo;Shin, Dong Ho;Park, Sung Soo
Tuberculosis and Respiratory Diseases
/
v.65
no.4
/
pp.334-338
/
2008
Solitary fibrous tumors of the pleura (SFTPs) are relatively rare tumors that originate from the mesenchymal cells of the submesothelial tissue of the pleura. Patients with SFTPs are often asymptomatic, while some patients experience pleuritic chest pain, cough and/or dyspnea. We report here on a case of SFTP, and the patient presented with septic shock and respiratory failure that required mechanical ventilation. A 68-year-old woman was admitted for the evaluation of her dyspnea and generalized edema. Chest imaging studies showed an 18 cm-sized voluminous mass occupying the right thoracic cavity with anterior displacement of hilar structures and atelectasis of the right lung. Immediately after admission, she developed pneumonia and septic shock that required antibiotics and mechanical ventilation. She displayed a partial response to medical treatment, and then complete excision of the tumor was performed and the pathologic examination revealed benign SFTP. Afterward, she fully improved without evidence of recurrence until now.
The Geopung Cu deposit consists of two subparallel quartz veins that till the NE-trending fissures in Triassic Cheongsan granite. The quartz veins occur mainly massive with partially cavity and breccia. They can be followed along strike for about 500 m and varies in thickness from 0.2 to 2.2 m. Based on the mineralogy and paragenesis of veins, mineralization of quartz veins can be divided into hypogene and supergene stages. Hypogene stage is associated with hydrothermal alteration minerals such as sericite, pyrite, quartz, chlorite, clay minerals and sulfides such as pyrite, arsenopyrite, pyrrhotite, marcasite, sphalerite, stannite, chalcopyrite and galena. Supergene stage is composed of geothite. Fluid inclusion data from quartz indicate that homogenization temperatures and salinity of hypogene stage range from 163 to $356^{\circ}C$ and from 0.2 to 7.2 wt.% eq. NaCl, respectively. They suggest that ore forming fluids were progressively cooled and diluted from mixing with meteoric water. Sulfur (${\delta}^{34}S$: 4.3~9.2‰) isotope composition indicates that ore sulfur was derived from mainly magmatic source although there is a partial derivation from the host rocks. The calculated oxygen (${\delta}^{18}O$: 0.9~4.0‰) and hydrogen (${\delta}D$: -86~-69‰) isotope compositions suggest that magmatic and meteoric ore fluids were equally important for the formation of the Geopung Cu deposit and then overlapped to some degree with another type of meteoric water during mineralization.
Kim, Jong-Sik;Jung, Chun-Young;Oh, Dong-Gyoon;Song, Ki-Won;Park, Young-Hwan
대한방사선치료학회:학술대회논문집
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2005.06a
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pp.23-26
/
2005
Introduction: To evaluate whether modified MUPIT applicator can effectively eradicate recurrent tumor in uterine cervix cancer and reduce rectal complication after complete radiation treatment. Methods and Materials: Modified MUPIT applicator basically consists of an acrylic cylinder with flexible brain applicator , an acrylic template with a predrilled array of holes that serve as guides for interstitial needles and interstitial needles. CT scan was performed to determine tumor volume and the position of interstitial needles. Modified MUPIT applicator was applied to patient in operation room and the accuracy for position of interstitial needles in tumor volume was confirmed by CTscan. Brachytherapy was delivered using modified MUPIT applicator and RALS (192-Ir HDR) after calculated computer planning by orthogonal film. The daily dose was 600cGy and the total dose was delivered 3000cGy in tumor volume by BID. Rectal dose was measured by TLD at 5 points so that evaluated the risk of rectal complication. Result: The application of modified MUPIT applicator improved dramatically dose distributions in tumor volume and follow-up of 3 month for this patient was clinically partial response without normal tissue complication, Rectal dose was measured 34.1cGy, 57.1cGy, 103.8cGy, 162.7cGy, 165.7cGy at each points, especially the rectal dose including previous EBRT and ICR was 34.1cGy, 57.1cGy Conclusion: Patients with locally recurrent tumor in uterine cervix cancer treated with modified MIUPIT applicator can expect reasonable rates of local control. The advantages of the system are the fixed geometry Provided by the template and cylinders, and improved dose distributions in irregular tumor volume without rectal complication
Kim, Do-Hoon;Pyon, Jai-Kyong;Mun, Goo-Hyun;Bang, Sa-Ik;Oh, Kap-Sung;Lim, So-Young
Archives of Plastic Surgery
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v.38
no.5
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pp.616-620
/
2011
Purpose: Mayer-Rokitansky-Kuster syndrome (MRK) is second common cause of primary amenorrhea. It is a syndrome of vaginal aplasia and Mullerian duct anomaly. Vaginal aplasia varies from agenesis of whole vagina to aplasia of upper 2/3. For reconstructing vagina, various methods are introduced. Gracilis myocutaneous flap was the first attempt in that the flap is used in vaginal reconstruction. Various flap-based vaginal reconstruction methods have been introduced. Modified Singapore flap (pedicled neurovascular pudendal thigh fasciocutaneous flap) is one of those methods that used posterior labial artery as pedicle, and pudendal nerve branch as sensory root. As its donor lies on inguinal crease that is easily hidden and there are benefits on sexual intercourse by early sensory recovery, authors think that modified Singapore flap is effective for young MRK syndrome patients. Methods: Eight patients underwent surgery between 2008 and 2010. The flap was designed on both groin area with external pudendal artery branch as a pedicle. All flaps were fixated in pelvic cavity with absorbable suture, and additional compression on neovaginal wall was supplied by polyvinyl alcohol sponge ($Merocel^{(R)}$). Results: All patients were successfully reconstructed without flap related complications such as congestion or partial flap loss. The average size of the flap (each side) was 69.34 $cm^2$. Polyvinyl alcohol sponge ($Merocel^{(R)}$) was inserted into neovagina for 5 days on every patient. One case of rectal laceration was occurred while making pelvic pocket by OBGY team. Other complications such as lumen narrowing, wound contracture or vaginal prolapsed were not reported during 8 months of follow up. Conclusion: Modified Singapore flap is a sensate fasciocutaneous flap that is thinner than other myocutaneous flap such as VRAM, and more durable over skin graft. Therefore this is a good choice for vaginal reconstruction in MRK syndrome. And known complications of Modified Singapore flap could be reduced with careful procedure and mild compression techniques.
Park, Sung Mi;Lee, Myeong Seong;Kim, Jae Hwan;Lee, Chan Hee
Korean Journal of Heritage: History & Science
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v.45
no.1
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pp.86-101
/
2012
The constituting rocks of Multi-storied Round shape stone Pagoda of Unjusa Temple are lithic tuff and rhyolite tuff breaccia which show green or grey and also rock fragment with poor roundness are present in the structure. lithic tuff is composed of feldspar and quartz which are glassy texture and cryptocrystalline and also micro crystalline are scattered. phenocryst quartz and feldspar in the substrate composed of feldspar and opaque minerals are found in rhyolite tuff breaccia. dust, exfoliation, cavity, fracture and crack are observed in all the stone of the pagoda and the result of Infrared Thermography shows partial inter cavities have developed severely which may cause further exfoliation. In addition, a great deal of various grey, green, and yellow brown lichen as well as bryophyte are present at the upper part of eastern and western roof stone located above the third floor. Discolors remarkably shown at stereobate and roof stone are identified as inorganic pollutants such as manganese oxide, iron oxide and iron hydroxide. The stone of the pagoda of the Chemical Index of Alteration (CIA) and the Weathering Potential Index (WPI) are 55.69 and 1.12 respectively and this corresponds to a highly weathered stage. The measured values, average ultrasonic velocity 2,892m/s, coefficient of weathering 0.4k and compressive strength $1,096kg/cm^3$, suggest that the rock strength and durability are weakened.
Although gag reflex is an essential function and a useful physiological defense mechanism, it can become an obstacle in a dental treatment. In this case, a questionnaire was designed and used in consultations to objectify the factors associated with gag reflex. Based on the questionnaire, various treatment protocols were planned, such as behavioral control, which is a systematic desensitization that adapts by placing dental instruments in the oral cavity, and habit control to eliminate vomiting habits after drinking. Except for the placement of the implant fixture under general anesthesia, all restoration procedures were performed in the outpatient clinic in the same manner as the conventional implant fixed prosthetic restoration. The systematic desensitization and behavior technique were repeated until the patient was able to endure discomfort and relieve gag reflex in dental treatment. The patient was successfully received the implant-fixed prosthetic restoration in the partial edentulous region.
Journal of Dental Rehabilitation and Applied Science
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v.37
no.4
/
pp.281-293
/
2021
Patients who went through maxillectomy can have severely impaired swallowing, mastication, and pronunciation functions because of palatal defects. Leakage occurs through the nasal cavity while eating, chewing becomes difficult due to the loss of teeth and alveolar ridges, and oral and nasal passages are not separated, leading to hyper-nasal sound, and significantly reducing the quality of life. To prosthetically reconstruct the defect, the weight of the obturator should be reduced as much as possible to minimize dropout because of gravity, and the bulb of the obturator should be properly extended into the defect to get additional retention and stability. In this case of a partially edentulous patient who underwent additional maxillary resection because of tumor recurrence, a metal framework was designed by applying the basic design principles of removable partial dentures. An obturator with improved retention, stability, and support was fabricated through functional impressions. The patient was satisfied with the improved facial expression, mastication, swallowing, and pronunciation, and showed stable occlusion and oral hygiene management during the follow-up period.
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