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Pharmaco-mechanical Thrombectomy and Stent Placement in Patients with May-Thurner Syndrome and Lower Extremity Deep Venous Thrombosis (May-Thurner 증후군과 동반된 하지 심부정맥혈전환자에서 혈전제거술과 스텐트삽입술)

  • Jeon, Yonh-Sun;Kim, Yong-Sam;Cho, Jung-Soo;Yoon, Yong-Han;Baek, Wan-Ki;Kim, Kwang-Ho;Kim, Joung-Taek
    • Journal of Chest Surgery
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    • v.42 no.6
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    • pp.757-762
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    • 2009
  • Background: Compression of the left common iliac vein by the overriding common iliac artery is frequently combined with acute deep vein thrombosis in patients with May-Thurner Syndrome. We evaluate the results of treatment with thrombolysis and thrombectomy followed by stenting in 34 patients with May-Thurner Syndrome combined with lower extremity deep venous thrombosis. Material and Method: The authors retrospectively reviewed the records of 34 patients (mean age: $65{\pm}14$ year old) who had undergone stent insertion for acute deep vein thrombosis that was caused by May-Thurner syndrome. After thrombectomy and thrombolysis, insertion of a wall stent and balloon angioplasty were performed to relieve the compression of the left common iliac vein. Urokinase at a rate of 80,000 to 120,000 U/hour was infused into the thrombosed vein via a multi-side hole thrombolysis catheter. A retrieval inferior vena cava (IVC) filter was placed to protect against pulmonary embolism in 30 patients (88%). Oral anticoagulation with warfarin was maintained for 3 months, and follow-up Multi Detector Computerized Tomography (MDCT) angiography was done at the date of the patients' hospital discharge and at the 6 months follow-up. Result: The symptoms of deep venous thrombosis disappeared in two patients (4%), and there was clinical improvement within 48 hours in twenty eight patients (82%), but there was no improvement in four patients (8%). The MDCT angiography at discharge showed no thrombus in 9 patients (26%) and partial thrombus in 21 (62%), whereas the follow-up MDCT at $6.4{\pm}5.5$ months (32 patients) revealed no thrombus in 23 patients (72%), and partial thrombus in 9 patients (26%). Two patients (6%) had recurrence of DVT, so they underwent retreatment. Conclusion: Stent insertion with catheter-directed thrombolysis and thrombectomy is an effective treatment for May-Thurner syndrome combined with acute deep vein thrombosis in the lower extremity.

Baleen Whale Sound Synthesis using a Modified Spectral Modeling (수정된 스펙트럴 모델링을 이용한 수염고래 소리 합성)

  • Jun, Hee-Sung;Dhar, Pranab K.;Kim, Cheol-Hong;Kim, Jong-Myon
    • The KIPS Transactions:PartB
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    • v.17B no.1
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    • pp.69-78
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    • 2010
  • Spectral modeling synthesis (SMS) has been used as a powerful tool for musical sound modeling. This technique considers a sound as a combination of a deterministic plus a stochastic component. The deterministic component is represented by the series of sinusoids that are described by amplitude, frequency, and phase functions and the stochastic component is represented by a series of magnitude spectrum envelopes that functions as a time varying filter excited by white noise. These representations make it possible for a synthesized sound to attain all the perceptual characteristics of the original sound. However, sometimes considerable phase variations occur in the deterministic component by using the conventional SMS for the complex sound such as whale sounds when the partial frequencies in successive frames differ. This is because it utilizes the calculated phase to synthesize deterministic component of the sound. As a result, it does not provide a good spectrum matching between original and synthesized spectrum in higher frequency region. To overcome this problem, we propose a modified SMS that provides good spectrum matching of original and synthesized sound by calculating complex residual spectrum in frequency domain and utilizing original phase information to synthesize the deterministic component of the sound. Analysis and simulation results for synthesizing whale sounds suggest that the proposed method is comparable to the conventional SMS in both time and frequency domain. However, the proposed method outperforms the SMS in better spectrum matching.

Partial purification and Properties of Alkaline Cellulase from Pseudomonas sp. AC-711 (Pseudomonas sp. AC-711이 생산하는 알칼리성 Cellulase의 부분정제 및 효소적 성질)

  • Yoon, Min-Ho;Lim, Sang-Ho;Choi, Woo-Young
    • Korean Journal of Agricultural Science
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    • v.25 no.1
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    • pp.131-137
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    • 1998
  • The cellulase components were partially purified from the culture filtrate of the alkalophilic bacterium Pseudomonas sp. AC-711 and its enzymatic properties were characterized. The specific activity of the purified major enzyme component was 3.5 units/mg protein as carboxymethyl cellulase and the yield was 23% of the total activity of the culture broth. The molecular weight of the component was 46,000 and the Km and Vmax on CMC were determined as $15.4mg\;mL^{-1}$ and $4.17{\mu}moles\;mL^{-1}\;min^{-1}$, respectively. The enzyme was stable at the temperatures below $60^{\circ}C$ and at the pH range of 4.0~11.0, and the optimal temperature and pH were $60^{\circ}C$ and pH 8.0, respectively. The enzyme activity was not significantly affected by the common surfactants (concentration: 0.05%) such as ${\alpha}$-olefin sulfonate, linear alkylbenzene sulfonate, sodium dodecyl sulfonate, hexadecyltrimethylammonium bromide and Tween 80. The enzyme was activated by the metal ions such as $Ca^{2+}$, $Cu^{2+}$, $Co^{2+}$, whereas inhibited by $Hg^{2+}$ and $Zn^{2+}$. The enzyme exhibited relatively high activity toward amorphous CMC as compared with crystalline substrates such as filter paper and avicel.

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Assessment for Effect of Water Environment by Addition of Improvement Agents on Sediments (저질 개선제의 주입에 의한 수 환경에 미치는 영향 평가)

  • Kim Woo-Hang;Kim Do-Hee
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.10 no.1 s.20
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    • pp.69-73
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    • 2004
  • Control if Sediment is very important in prawn farm due to the eruption of toxic materials such as unionized $H_{2}S,\;NH_{3}\;and\;NO_3$. In this study, column test was conducted with filter media such as activated carbon, zeolite, oyster shell and iron chloride to evaluate the reduction of toxicity from sediment. ammonia-N($NH_3$) was effectively removed by Zeolite and oyster shell. It was indicated that ammonium ion($NH_4^+$) was removed by ion exchange of zeolite. And the ammonia in the column of oyster shell was existed as the form of $NH_4^+$, which is not toxic for prawn because oyster shell was stably kept at $8{\sim}9g$ of pH. Therefore, some of ammonia($NH_4^+$) was removed by oyster shell. Hydrogen sulfide and COD were effectively removed by adsorption of activated carbon and a partial removal of hydrogen sulfide was accomplished by Oyster shell. Phosphorous was removed by activated carbon, oyster shell and iron chloride. In prawn farm, the concentration of ammonia was increased with increase of pH by algae photosynthesis in the column of activated carbon, zeolite and iron chloride, but it was revealed that pH was stably kept in the column of oyster shell.

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Towards 3D Modeling of Buildings using Mobile Augmented Reality and Aerial Photographs (모바일 증강 현실 및 항공사진을 이용한 건물의 3차원 모델링)

  • Kim, Se-Hwan;Ventura, Jonathan;Chang, Jae-Sik;Lee, Tae-Hee;Hollerer, Tobias
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.46 no.2
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    • pp.84-91
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    • 2009
  • This paper presents an online partial 3D modeling methodology that uses a mobile augmented reality system and aerial photographs, and a tracking methodology that compares the 3D model with a video image. Instead of relying on models which are created in advance, the system generates a 3D model for a real building on the fly by combining frontal and aerial views. A user's initial pose is estimated using an aerial photograph, which is retrieved from a database according to the user's GPS coordinates, and an inertial sensor which measures pitch. We detect edges of the rooftop based on Graph cut, and find edges and a corner of the bottom by minimizing the proposed cost function. To track the user's position and orientation in real-time, feature-based tracking is carried out based on salient points on the edges and the sides of a building the user is keeping in view. We implemented camera pose estimators using both a least squares estimator and an unscented Kalman filter (UKF). We evaluated the speed and accuracy of both approaches, and we demonstrated the usefulness of our computations as important building blocks for an Anywhere Augmentation scenario.

Dietary Value of Candida utilis for Artemia Nauplii and Mytilus edulis Larvae (Artemia nauplii와 Mytilus edulis 유생에 대한 Candida utilis의 먹이효율)

  • Kim, Hae-Young;Kim, Jung-Kyun;Hur, Sung-Bum
    • Journal of Aquaculture
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    • v.22 no.1
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    • pp.68-73
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    • 2009
  • Yeast has been widely used as a food organism for mass culture of rotifer and also considered as a partial substitute food for microalga in shellfish culture. But the dietary value of yeast is poorer than that of microalga due to its low nutrition and thick cell wall. This study was carried out to find a nutritious yeast species as a food organism and to investigate the nutritional value of manipulated yeast for shellfish. First of all, three species of yeast (Saccharomyces cerevisiae, Candida utilis, Kluyveromyces fragilis) and their manipulated yeast were tested on the survival (%) and growth of Artemia nauplii and Mytilus edulis larvae, which were representative filter feeding animal and easy to control. The survival (%) and growth of Artemia nauplii fed C. utilis were higher than those fed S. cerevisiae or K. fragilis. The growth of Artemia nauplii and M. edulis larvae, which were fed manipulated yeast was higher than that fed non-manipulated one. The manipulated yeast with higher removal rate of cell wall showed better dietary value for Artemia nauplii and M. edulis larvae. M. edulis larvae fed mixed-diet with Isochrysis galbana (50%) and manipulated C. utilis (50%) showed significantly higher growth than those fed single-diet with I. galbana. It means that manipulated C. utilis can substitute I. galbana at least 50% for M. edulis larvae.

Design and Implementation of Query Classification Component in Multi-Level DBMS for Location Based Service (위치기반 서비스를 위한 다중레벨 DBMS에 질의 분류 컴포넌트의 설계 및 구현)

  • Jang Seok-Kyu;Eo Sang Hun;Kim Myung-Heun;Bae Hae-Young
    • The KIPS Transactions:PartD
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    • v.12D no.5 s.101
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    • pp.689-698
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    • 2005
  • Various systems are used to provide the location based services. But, the existing systems have some problems which have difficulties in dealing with faster services for above million people. In order to solve it, a multi-level DBMS which supports both fast data processing and large data management support should be used. The multi-level DBMS with snapshots has all the data existing in disk database and the data which are required to be processed for fast processing are managed in main memory database as snapshots. To optimize performance of this system for location based services, the query classification component which classifies the queries for efficient snapshot usage is needed. In this paper, the query classification component in multi-level DBMS for location based services is designed and implemented. The proposed component classifies queries into three types: (1) memory query, (2) disk query, (3) hybrid query, and increases the rate of snapshot usage. In addition, it applies division mechanisms which divide aspatial and spatial filter condition for partial snapshot usage. Hence, the proposed component enhances system performance by maximizing the usage of snapshot as a result of the efficient query classification.

NEW EVALUATION METHODS FOR RADIAL UNIFORMITY IN NEUTRON TRANSMUTATION DOPING

  • Kim, Hak-Sung;Lim, Jae-Yong;Pyeon, Cheol-Ho;Misawa, Tsuyoshi;Shiroya, Seiji;Park, Sang-Jun;Kim, Myong-Seop;Oh, Soo-Youl;Jun, Byung-Jin
    • Nuclear Engineering and Technology
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    • v.42 no.4
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    • pp.442-449
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    • 2010
  • Recently, the neutron irradiation for large diameter silicon (Si)-ingots of more than 8" diameter is requested to satisfy the demand for the neutron transmutation doping silicon (NTD-Si). By increasing the Si-ingot diameter, the radial non-uniformity becomes larger due to the neutron attenuation effect, which results in a limit of the feasible diameter of the Si-ingot. The current evaluation method has a certain limit to precisely evaluate the radial uniformity of Si-ingot because the current evaluation method does not consider the effect of the Si-ingot diameter on the radial uniformity. The objective of this study is to propose a new evaluation method of radial uniformity by improving the conventional evaluation approach. To precisely predict the radial uniformity of a Si-ingot with large diameter, numerical verification is conducted through comparison with the measured data and introducing the new evaluation method. A new concept of a gradient is introduced as an alternative approach of radial uniformity evaluation instead of the radial resistivity gradient (RRG) interpretation. Using the new concept of gradient, the normalized reaction rate gradient (NRG) and the surface normalized reaction rate gradient (SNRG) are described. By introducing NRG, the radial uniformity can be evaluated with one certain standard regardless of the ingot diameter and irradiation condition. Furthermore, by introducing SNRG, the uniformity on the Si-ingot surface, which is ignored by RRG and NRG, can be evaluated successfully. Finally, the radial uniformity flattening methods are installed by the stainless steel thermal neutron filter and additional Si-pipe to reduce SNRG.

Production of Antithrombotic Material Extracted from Auricularia auricular-judae and the Verification of Its Antithrombotic Activity via Animal Test (목이버섯으로부터 추출한 항혈전물질의 제품화와 동물실험을 통한 항혈전활성 검증)

  • Park, Young-Seo;Choi, Hyuk-Joon
    • Food Engineering Progress
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    • v.14 no.4
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    • pp.359-366
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    • 2010
  • Large-scale preparation steps of antithrombotic materials from wood ear mushroom (Auricularia auricular-judae) were established as follows. Grounded dry wood ear mushroom was extracted with 75% ethanol and its precipitate was extracted with $76^{\circ}C$ water for 2 hr followed by filter pressing. The filtrate was then concentrated by vacuum and extracted with 80% ethanol, and the resulting precipitate was then freeze-dried. The formula of the product was determined using consumer susceptibility tests as follows; mushroom extract 90.5%, high fructose corn syrup 2.0%, $\beta$-cyclodextrin 1.5%, fructo-oligosaccharide 2.0%, pear puree 4.0%. When the packed products were stored at 25, 37, or $45^{\circ}C$ for 8 weeks, there were no noticeable changes in water activity, moisture content, pH, and acidity. The viable cell number of total bacteria was slightly increased during the storage period at 25 and $37^{\circ}C$, The total bacteria were not detected in the product when stored at $45^{\circ}C$. When the product was injected intravenously into rat at the level of 1,000 mg/kg, antithrombotic activities such as activated partial thromboplastin time, thrombin time, prothrombin time, and FIB were increased when compared with the control group. When the product was administrated orally into rat at the level of 500 mg/kg, it showed the same antiplatelet activity to aspirin.

Magnetic Properties of Heteroepitaxial $Y_{3}Fe_{5)O_{12}$ Films Grown by a Pulsed Laser Ablation Technique (펄스 레이저 증착기술에 의한 $Y_{3}Fe_{5)O_{12}$ 에피택셜 박막제조)

  • Yang, C.J.;Kim, S.W.
    • Journal of the Korean Magnetics Society
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    • v.5 no.2
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    • pp.128-133
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    • 1995
  • Yttrium Iron Garnet($Y_{3}Fe_{5)O_{12}$) films have been succsssfully grown on(111)GGG wafer by KrF excimer laser ablation of stoichiometric garnet target at the oxygen partial pressure, $P(O_{2}$, ranging 20 to 500 mTorr. During the deposition of the films the substrate temperature was maintained at $700^{\circ}C$ and the laser beam energy density at $7.75\;J/cm_{2}$. Microstructure, composition and magnetic properties of the films obtained were investigated as a function of oxygen pressure and thickness of the films. Epitaxial films with a dense and a smooth surface were reproducible at a low oxygen pressure. The films of $2.75\;{\mu}$ min thickness deposited at 20 mTorr of $P(O_{2})$ showed $4{\pi}M_{s}$ of 1500 Gauss and $H_{c}$ of 3 Oe after annealing at $800\;^{\circ}C$ for 20 minutes. As-deposited films of $0.8\;\mu\textrm{m}$ in thickness exhibited the $4{\pi}M_{s}$ of 1730 Gauss and $H_{c}$ of 7 Oe. The magnetic properties of the films obtained were almost identical to those of a single crystal YIG.

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