• 대한한의학회지
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• 제19권2호
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• pp.420-438
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• 1998

Herba Xanthii(HX), Radix Xantluii(RX) and Fructus Xanthii(FX) is one of the oriental medicine that has been used for the treatment of such infectious diseases and tumors. However, the mechanism of the drug is not investigated much. This study was done to know the effects of HX, RX and FX extract on the such innate immunities as phagocytic function and reactive radical formtions from phagocytes and the such acquired immunities as humoral and cell-mediated immunities. The followings are the results obtained from this study: 1. HX2 and FX1 groups increases the in vivo phagocytic activity of mononuclear phagocytes. 2. HXB, RXB, RXC, FXB and FXC groups increase the in vitro phagocytic activities. 3. RXB group stimulated the macrophages to produce nitric oxide in the presence of $interferon-{\gamma}$ $(IFN-{\gamma})$. 4. HX and RX whole groups increased the luminol-amplified reactive oxygen intermediate production in vivo. 5. HX whole and RX1, FX2 groups increased the lucigenin-amplified reactive oxygen intennediate production in vivo. 6. HXC group only increased the luminol-amplified reactive oxygen intermediate production in vitro. 7. HXB, FXB and FXC groups increased the lucigenin-amplified reactive oxygen intermediate production in vitro. 8. HX2, RX1 and FX whole groups increased the hemolysin formations from B cells. 9. HX, RX and FX whole groups significantly increased the rosette forming cells from the spleen. 10. HX, RX and FX whole groups significantly decreased the delayed-type hypersensitivity measured by footpad swelling. The above results demonstrate that HX, RX and FX has enhancing effects on innate immunity selectively and decreasing effects on delayed-type hypersensitivity of cell-mediated immunity according to medicinal part and diluted condition. This immunomodulating effects of HX, RX and FX might be responsible for the treatment of immune-mediated disorders.

• 패션비즈니스
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• 제9권1호
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• pp.79-88
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• 2005

The purpose of this study is to propose the design of the patient's clothes for a disabled child between 4 and 6. For this, in this study, I would present the following design plan which includes 3 upper garments, 2 trousers and a one-piece dress. In case of the damage on head and neck, a neck line should be deep and wide thereby providing ease to the clothes. To facilitate injection and dressing/undressing, there should be parting from neck to cuff which can be fixed by snap or button. By rolling up sleeves with strings inside the cuffs and fixating plaster cast with snap button outside the cuffs. In case of body cast with plaster cast around body part, front adjusting part should be wider and the width should be adjusted with strings. In case of hip spica cast which covers waist, I separated front part and rear part, fixated them with snap buttons, gave more width to front adjusting part with strings to adjust width, which constitute one-piece dress. In case of shoulder spica cast, the other shoulder which is not covered with plaster cast should be exposed, and to prevent clothes' coming down, strings with snap button or velcro should be attached over a shoulder so that the length of the strings can be adjusted. In case of applying plaster cast or aid to the whole part of a leg, one part of trousers should be shorter so as to expose the injured part and there should be a parting with strings or velcros on the side for easy dressing/undressing. When plaster cast or splint is short, The strings are meant to adjust length of trousers. The partings are located 2 cm from side lines toward the center.

• 대한한의학방제학회지
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• 제25권2호
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• pp.303-324
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• 2017

Objectives : Consumptive is an unhealthy condition that are caused by lack of blood and essence, and that means also some stages of chronic diseases. The purpose of this study is to analysis 108 Prescriptions of Consumptive part in Dongui Bogam. Methods : The 108 Prescriptions of Consumptive part in Dongui Bogam analysed frequency of basic prescriptions, symptoms of prescriptions and the pathology. Results : Ssangbohwan, Yiuihwan, Gamrihwan were used for tonifying were mostly used as basic prescriptions in whole Consumptive part respectively. There are common symptoms in consumptive part in Dongui Bogam. That symptoms are "tidal fever, night sweating, nocturnal emission, cough, sputum, skinny body, weak pulse, spontaneous sweating, deafness, dim vision and tuberculosis". Qi blood(yin yang) pathologies in prescriptions on consumptive part are "yin deficiency, yin deficiency with effulgent fire, yang qi deficiency, dual damage of qi and blood, non-interaction between fire and water, collapse of yang and exhaustion of yin, less blood". viscera and bowels pathologies in prescriptions on consumptive part are "heart and kidney deficiency, spleen-stomach weakness, spleen and kidney great deficiency, weakness of kidney qi, meridian waste in heart, spleen and kidney, damage in heart and lung". Conclusions : As a result of Study on Analysis all Prescriptions of Consumptive part in Dongui Bogam, We can understand more about basic prescriptions, symptoms of prescriptions and the pathology that are using for curing consumptive. We expected that this study will can help to give rationale for future study of consumptive caring.

• 한국의류학회지
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• 제26권10호
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• pp.1443-1454
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• 2002

The purposes of this study were to classify body type of adult males into several kind of shape and to provide the characteristics of size of each group which has same shape. As the sample, subjects were 1290 males of 20 to 54 year-old. The procedure and results were follows; 1. As the result of the previous reserch, the front line of body was classified in X, H, Y and A types. 2. The principal component analysis was used to obtain the shape factor of the side line of the trunk. 9 factors in the side were extracted. As the result of the cluster analysis of factor scores, the side line of body was classified in 5 types. It was named X, A, Y and H type in the front and S, D1, d, I and D2 type in the side. 3. In order to consider the shape of body as a whole, the body shape of the front and side were compounded. The whole body shapes of adult male were very various, and 6 body shapes, XS, YS, Yd, YI, AD2 and HD1 were selected as the basic types. In each type of body, several groups were classified by size factor, height and chest girth and master size was selected considering appearance frequency.

• 대한수학교육학회지:수학교육학연구
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• 제21권1호
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• pp.1-16
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• 2011

이 연구는 개정 교육과정에 근거한 초등학교 수학 교과서와 지도서의 자연수 나눗셈 영역에 대한 고찰이다. 교과서와 지도서는 수학을 지도하기 위한 가장 중요한 문서이다. 또한, 장차 초등학교에서 수학을 가르치려는 예비교사들이 교과서와 지도서를 바탕으로 학습하기 때문에 이들에게도 매우 중요한 문건이다. 그러므로 교과서나 지도서에 문제가 없어야 한다. 그러나 자연수 나눗셈과 관련하여 개정 교과서와 지도서에 몇 가지 오류와 개선해야 할 점들이 나타났다. 이 연구에서는 그런 사항들에 대해 논하고 개선점을 제안하였다.

• Fisheries and Aquatic Sciences
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• 제2권2호
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• pp.135-141
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• 1999

In order to investigate the composition of extractive nitrogenous components in the diploid and the triploid oysters, Crassostrea gigas, cultured at the south coast of Korea, the whole edible part (whole body) was analyzed into extractive nitrogen, free amino acids, oligopeptides, ATP and its related compounds, quaternary ammonium bases, and guanidino compounds using specimens collected from April to May of 1992. The major free amino acids in the diploid and the triploid were taurine, proline, alanine, glycine, glutamic acid hypotaurine, glutamine, arginine, aspartic acid, and $\beta-alanine$. There was no conspicuous difference in the constituents of free amino acids between the diploid and the triploid. A lot of hypotaurine was detected in the diploid and the triploid of oyster and the contents of them were 107 mg and 123 mg/100g, respectively. The compounds, glycinebetaine, homarine and trigonelline were found in both the diploid and the triploid. Among them, glycinebetaine was the most prominent in all the samples. The amount of protein, glycogen, extractive nitrogen, oligopeptides, ATP and its related compounds, and free amino acids in the triploid was higher than that of the diploid (p<0.10)

• 약학회지
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• 제50권2호
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• pp.111-117
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• 2006

Cardiac chambers serve as mechanosensory systems during the haemodynamic or mechanical disturbances. To examine a possible role of fluid pressure (FP) in the regulatien of atrial $Ca^{2+}$ signaling we investigated the effect of FP on L-type $Ca^{2+}$ current $(I_{Ca})$ in rat ventricular myocytes using whole-cell patch-clamp technique. FP $(\sim40cm\;H_2O)$ was applied to whole area of single myocytes with electronically controlled micro-jet system. FP suppressed the magnitude of peak $I_{Ca}$ by $\cong25\%$ at 0 mV without changing voltage dependence of the current-voltage relationship. FP significantly accelerated slow component in inactivation of $I_{Ca}$, but not its fast component. Analysis of steady-state inactivation curve revealed a reduction of the number of $Ca^{2+}$ channels available for activity in the presence of FP. Dialysis of myocytes with high concentration of immobile $Ca^{2+}$ buffer partially attenuated the FP-induced suppression of $I_{Ca}$. In addition, the intracellular $Ca^{2+}$ buttering abolished the FP-induced acceleration of slow component in $I_{Ca}$ inactivation. These results indicate that FP sup-presses $Ca^{2+}$ currents, in part, by increasing cytosolic $Ca^{2+}$ concentration.

• 스마트미디어저널
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• 제5권1호
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• pp.49-54
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• 2016

Medical image processing is a compulsory process to diagnose many kinds of disease. Therefore, an automatic algorithm for this task is highly demanded as an important part to construct a computer-aided diagnosis system. In this paper, we introduce an automatic method to segment the liver region from 3D abdominal CT images using Otsu method. First, we choose a 2D slice which has most liver information from the whole 3D image. Secondly, on the chosen slice, we enhanced the image based on its intensity using Otsu method with multiple thresholds and use the threshold to enhance the whole 3D image. Then, we apply a liver mask to mark the candidate liver region. After that, we execute the Otsu method again to segment the liver region from the chosen slice and propagate the result to the whole 3D image. Finally, we apply preprocessing on the frontal side of 3D images to crop only the liver region from the image.

• 대한본초학회지
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• 제38권5호
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• pp.39-47
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• 2023

Objectives : The objective of present study was to investigate the vasorelaxant effects of 20 Korean native plants on isolated rat thoracic aorta precontracted with phenylephrine (PE). Methods : Dried 20 plant materials were extracted 3 times with water, ethanol, or methanol for 3h in the reflux apparatus at 70 ± 5℃. Male SD rats were anesthetized by ether inhalation, and their aorta rings were isolated and placed in 10 ㎖ Krebs Henseleit (KH) buffer. While using an isolated organ-chamber technique, the aorta rings were maintained by bubbling with a gas mixture of 95% O₂-5% CO₂ at 37℃. Changes in isometric tension of aorta rings were recorded via isometric transducers connected to a Powerlab Data Acquisition System. Results : Among the 20 native plants, Chrysanthemum indicum L. flower, Nelumbo nucifera Gaertn. rhizome, Schisandra chinensis (Turcz.) Baill. fruit, Anthriscus sylvestris (L.) Hoffm. root, Corydalis turtschaninovii Besser tuber, Corydalis decumbens (Thunb.) Pers. tuber, and Dolichos lablab L. seed showed significant vasorelaxant effect on the contraction of aorta rings induced by PE. In contrast, Mertensia maritima subsp. asiatica Takeda whole plant, Ajuga decumbens Thunb. whole plant, Trigonotis peduncularis (Trevis.) Benth. ex Baker & S.Moore whole plant, Dioscorea quinquelobate Thunb. rhizome, Allium microdictyon Prokh aerial part, Momordica charantia L. fruit, Carthamus tinctorius L. flower, and Clematis terniflora DC. root constricted more the aorta rings precontracted by PE Conclusion : These results suggest that the possibility as useful herbal resources for the development of functional foods or medicines for hypertension treatment.

• 로봇학회논문지
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• 제12권3호
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• pp.263-269
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• 2017

Recently, soft robots using soft materials are presented. Thanks to soft materials, soft robots have flexible, highly-stretchable or adaptable features. However, due to the flexibility of soft material, it is hard for soft robots to control accurately or perform high force. To deal with these limitations, variable stiffness technology, which enables the stiffness control of structure, has been developed. In this research, a dual-stiffness structure that is actuated by the assembly of two flexible structures are presented. Each flexible structure consists of flexible film part and rigid parts placed at regular intervals. The flexibility of film between rigid parts allows each structure to move softly. On the other hand, by combining two structures rigid part of each part constrain the degrees of freedom of the other side part. And this causes the stiffness of whole structure to be increased. This paper will cover concepts, design, analysis and experiments of this structure.