• The Korean Journal of Physiology and Pharmacology
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• v.19 no.3
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• pp.191-196
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• 2015

Attenuated functional exercise capacity in elderly and diseased populations is a common problem, and stems primarily from physical inactivity. Decreased function and exercise capacity can be restored by maintaining muscular strength and mass, which are key factors in an independent and healthy life. Resistance exercise has been used to prevent muscle loss and improve muscular strength and mass. However, the intensities necessary for traditional resistance training to increase muscular strength and mass may be contraindicated for some at risk populations, such as diseased populations and the elderly. Therefore, an alternative exercise modality is required. Recently, blood flow restriction (BFR) with low intensity resistance exercise (LIRE) has been used for such special populations to improve their function and exercise capacity. Although BFR+LIRE has been intensively studied for a decade, a comprehensive review detailing the effects of BFR+LIRE on both skeletal muscle and vascular function is not available. Therefore, the purpose of this review is to discuss previous studies documenting the effects of BFR+LIRE on hormonal and transcriptional factors in muscle hypertrophy and vascular function, including changes in hemodynamics, and endothelial function.

• Journal of Korean Clinical Health Science
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• v.4 no.4
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• pp.756-761
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• 2016

Purpose. Noise occurs at measuring Electoretinogram(ERG) signals as the other bio-signal measurement. It is compared the denoising performance according to the mother function of wavelet transforms. Methods. The ERG signal that generated power supply noise and white noise was used as a sampling signal. The noise of ERG signal was filtered by using haar, db7, bior mother function. The filtering performance of each mother functions was compared using Fourier transform spectrum and SNR(signal to noise ratio). Results. In the haar functioin, the result of the Fourier transform spectrum was that the power supply noise is removed and the white noise performance is not good. The SNR was 27.0404. In the db7 function, the results of Fourier transform spectrum was that the power supply noise is removed and the white noise performance is good. The SNR was 35.1729. In the db7 function, the results of Fourier transform spectrum was that the power supply noise is removed and the white noise performance is the bset. The SNR was 35.4445. Conclusions. The db7, bior function was good results in power supply noise and white noise filtered. The bior function is suitable for filtering noise of the ERG signal.

• Journal of the Korea Society of Computer and Information
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• v.21 no.12
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• pp.131-137
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• 2016

In this paper, the peak finding algorithms corresponding to the Autocorrelation Function (ACF), which are widely exploited for detecting the pitch of voiced signal, are proposed. According to various researchers, it is well known fact that the estimation of fundamental frequency (F0) in speech signal is not only very important task but quite difficult mission. The proposed algorithms, presented in this paper, are implemented by using many characteristics - such as monotonic increasing function - of ACF function. Thus, the proposed algorithms may be able to estimate both reliable and correct the fundamental frequency as long as the autocorrelation function of speech signal is accurate. Since the proposed algorithms may reduce the computational complexity it can be applied to the real-time processing. The speech data, is composed of Korean emotion expressed words, is used for evaluation of their performance. The pitches are measured to compare the performance of proposed algorithms.

• Journal of the Korean Institute of Landscape Architecture
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• v.51 no.3
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• pp.21-36
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• 2023

As a solution to environmental issues, such as climate change response, the carbon neutrality strategy, urban heat islands, fine dust, and biodiversity enhancement, the value of urban green spaces and trees are becoming important, and various studies dealing with the effects of trees for environmental improvement are being conducted. This study comprehensively considers the preceding studies on planting tree species, planting structure, planting density, and planting base to propose a direction for the planting renewal of green areas in urban parks and applies the findings to a renewal plan to improve the urban environment through landscaping trees. A field survey was conducted on the planting status of Seoul Children's Grand Park, a large-scale neighborhood park in Seoul, and based on the survey data, a planting function evaluation was conducted, and areas needing improvement in planting function were identified. The planting function evaluation was carried out considering the park function setting, planting concept according to spatial function, and planting status. As a result of the study, the direction of planting renewal according to functional change was derived for each stage of planting function evaluation. Increasing the green area ratio is a priority in setting up park functions, but user convenience should also be considered. As a concept of planting, visual landscape planting involves planting species with beautiful tree shapes, high carbon absorption, and fine dust reduction effects. Ecological landscape planting should create a multi-layered planting site on a slope. Buffer planting should be created as multi-layered forests to improve carbon absorption and fine dust reduction effects. Green planting should consist of broad-leaved trees and herbaceous layers and aim for the natural planting of herbaceous species. For plant species, species with high urban environment improvement effects, local native species, and wild bird preferred species should be selected. As for the planting structure, landscape planting sites and green planting sites should be composed of trees, shrubs, and trees and herbaceous layers that emphasize ecology or require multi-layered buffer functions. A higher standard is applied based on the planting interval for planting density. Installing a rainwater recycling facility and using soil loam for the planting base improves performance. The results of this study are meaningful in that they can be applied to derive areas needing functional improvement by performing planting function evaluation when planning planting renewal of aging urban parks and can suggest renewal directions that reflect the paradigm of functional change of created green areas.

• Physical Therapy Korea
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• v.21 no.3
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• pp.55-62
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• 2014

This study investigated the relationship between function classification systems and the Pediatric Evaluation of Disability Inventory (PEDI) functional skills in children with cerebral palsy (CP). Two hundred and eleven children with CP participated in this study. The Korean-Gross Motor Function Classification System (K-GMFCS), Korean-Manual Ability Classification System (K-MACS), Korean-Communication Function Classification System (K-CFCS), and self-care, mobility, and social function domains of the Korean-Pediatric Evaluation of Disability Inventory (K-PEDI) functional skills were measured by physical therapists or occupational therapists. All of the function classification systems were significantly correlated with PEDI functional skills ($r_s$=-.549 to -.826) (p<.05). Especially, K-GMFCS, K-MACS, and K-CFCS were correlated significantly with mobility, self-care, and social function, respectively. Using stepwise multiple regression analysis, we established that K-GMFCS, K-MACS, and K-CFCS were predictors of self-care skills (74.3%) and mobility skills (79.5%) of the K-PEDI (p<.05). In addition, K-CFCS and K-MACS were predictors of social function (65.9%) of the K-PEDI (p<.05). The information gathered in this study using the levels measured in the function classification systems may be useful to clinicians for estimating the PEDI functional skills in children with CP.

• Journal of Korean Physical Therapy Science
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• v.27 no.2
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• pp.13-24
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• 2020

Background: This study evaluates physical function, balance, and cognition rehabilitation motivation. Design: Cross-sectional study. Methods: The subjects include 67 stroke patients to measure physical function, balance, and cognition rehabilitation motivation. For evaluation of physical function, Manual Muscle Test, Range of Motion, Modified Ashworth Scale for spasticity, grasping power, and balance was measured using Functional reach test (FRT), Berg Balance Scale (BBS). For evaluating Cognition, Korean-Mini Mental State Examination, motivation for rehabilitation scale was used to measure for motivation. Results: The results of this study that the moderating effect of rehabilitation motivation was significant in the effect of physical function on BBS (p<0.01), The moderating effect of rehabilitation motivation was significant in the effect of FRT on physical function (p<0.01), The moderating effect of external motivation was also significant in the effect of FRT on physical function (p<0.01). However, the results of the rehabilitation motivations generally divided into three groups (Lower, Average, Upper) and all three results were statistically significant only in groups of average and lower. Conclusion: This study confirms that the rehabilitation motive has demonstrated significant adjustment effects between the body function and balance. In this study, physical function, balance and cognition were significantly correlated with each other, and rehabilitation motivation proved a significant moderating effect between physical function and balance.

• Journal of KIISE:Software and Applications
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• v.33 no.8
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• pp.655-667
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• 2006

This paper proposes a method for counting function point using goal and scenario based requirements. Function Point is a software sizing method and widely used as a basis to estimate software development cost. Requirements elicitation and analysis should be performed before function point analysis but function point analysis method doesn't deal with requirements elicitation and analysis. For that reason, Function point extraction method from existing requirements method is needed and if the requirements method has advantage for traceability and elicitation, it is suitable for managing cost. Goal and scenario method is widely used as requirements elicitation and analysis. It has also good traceability. Therefore, this paper discusses a method for extracting function point from requirements text gathered using the goal and scenario based requirements elicitation technique. The proposed method aims to establish and maintain traceability between function point and requirements text. Text based function point extraction guidance rules have been developed. The proposed methodology has been applied to Order Processing System development.

• Experimental and Molecular Medicine
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• v.50 no.11
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• pp.12.1-12.12
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• 2018

Drugs targeting the epidermal growth factor receptor (EGFR), such as cetuximab and panitumumab, have been prescribed for metastatic colorectal cancer (CRC), but patients harboring KRAS mutations are insensitive to them and do not have an alternative drug to overcome the problem. The levels of ${\beta}$-catenin, EGFR, and RAS, especially mutant KRAS, are increased in CRC patient tissues due to mutations of adenomatous polyposis coli (APC), which occur in 90% of human CRCs. The increases in these proteins by APC loss synergistically promote tumorigenesis. Therefore, we tested KYA1797K, a recently identified small molecule that degrades both ${\beta}$-catenin and Ras via $GSK3{\beta}$ activation, and its capability to suppress the cetuximab resistance of KRAS-mutated CRC cells. KYA1797K suppressed the growth of tumor xenografts induced by CRC cells as well as tumor organoids derived from CRC patients having both APC and KRAS mutations. Lowering the levels of both ${\beta}$-catenin and RAS as well as EGFR via targeting the $Wnt/{\beta}$-catenin pathway is a therapeutic strategy for controlling CRC and other types of cancer with aberrantly activated the $Wnt/{\beta}$-catenin and EGFR-RAS pathways, including those with resistance to EGFR-targeting drugs attributed to KRAS mutations.

• Journal of the Korean Society of Physical Medicine
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• v.16 no.1
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• pp.103-109
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• 2021

PURPOSE: This study examined the effects of the Visual Analog Scale (VAS) and knee function index on the knee strength and endurance in the national male field-hockey athletes. METHODS: Twenty-four male field-hockey athletes with a painful knee who trained at the national training center in 2019 were enrolled. The VAS and knee function index questionnaire were used to evaluate the degree of pain and functional state of the knee. The muscle strength and endurance of the knee were measured by Biodex (System 4, USA). The Pearson product moment correlation was performed to examine the effects of the VAS and knee function index the of knee on the strength and endurance. In addition, the VAS and knee function index and muscle strength and muscle endurance were examined to determine the relationship using Simple Linear Regression. The statistical significance level was α=.05. RESULTS: An analysis of the correlation between VAS and knee function index and muscle strength and muscle endurance revealed the VAS and knee function index to be statistically significant (r = .700). In addition, the extensor muscle strength, knee VAS (r = -.457), and knee function index (r = -.414) were also statistically significant. A 1-point increase in the VAS and knee function index was associated with an approximately 9.881 and 1.006 extensor muscle strength. CONCLUSION: The VAS and knee function index of field-hockey athletes are related to the strength of the knee extensors. Therefore, field-hockey athletes should develop a program to strengthen the extensor muscle strength of the knee.

• Journal of Institute of Control, Robotics and Systems
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• v.4 no.2
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• pp.141-150
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• 1998

This paper presents a dynamical anti-reset windup (ARW) compensation method for saturating control systems with multiple controllers and/or multiloop configuration. By regarding the difference of controller states in the absence and presence of saturating actuators as an objective function, the dynamical compensator which minimizes the objective function is derived in an integrated fashion. The proposed dynamical compensator is a closed form of plant and controller parameters. The resulting dynamics of compensated controller reflects the linear closed-loop system. The proposed method guarantees total stability of the resulting system. The effectiveness of the proposed method is illustrated by applying it to a servo motor control system. The paper is an extension of the results in Park and Choi[1].