• 제목/요약/키워드: Park comparison

검색결과 9,899건 처리시간 0.046초

우귀음(右歸飮)이 난소적출(卵巢摘出) 백서(白鼠)의 골다공증(骨多孔症)에 미치는 영향(影響) (Effects of Woogwiyeum on the Ovariectomized Rat Model of Postmenopausal Osteoporosis)

  • 최창민;이수정;박경환;김송백;조한백
    • 대한한방부인과학회지
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    • 제19권4호
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    • pp.77-92
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    • 2006
  • Purpose : This study is to examine what are the effects of the Woogwiyeum(WGY) on the ovariectomized rat model of postmenopausal osteoporosis. Methods : We devide mice to 3 Group(Sham operated group, control group, WGY treated group) and analyze each serum component. Results : 1. Body weight in control group showed significant increase in comparison with sham, but that in WGY-treated showed no change in comparison with control. 2. The level of serum albumin, ALP in control group showed significant decrease in comparison with sham. That in WGY-treated was decreased in comparison with control. 3. Trabecular bone area as well as trabecular thickness in control group showed significant decrease in comparison with sham. Those in WGY-treated showed significant increase in comparison with control. 4. Osteoclast number and oseoblast surface in control group showed significant increase in comparison with sham. Those in WGY-treated showed significant decrease in comparison with control. Conclusion : WGY has shown to be capable of preventing and curing osteoporosis caused by old-aged and postmenopause.

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녹각(鹿角)이 난소적출로 유발된 흰쥐의 골다공증 치료효과에 미치는 영향 (Effect of Cervi Cornu On treatment of Osteoporosis in Ovariectomized Rats)

  • 황정수;서부일;박지하;노성수;김미려;김승모;구진숙
    • 대한본초학회지
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    • 제25권2호
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    • pp.1-10
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    • 2010
  • Objectives : The present study has been undertaken to investigate the effects of Cervi Cornu on treatment of osteoporosis in ovariectomized rats. Method : In this experiment, the rats were ovariectomized. Rats were administered by Cervi Cornu. The levels of bone mineral density, osteocalcin, ALP, calcium, phosphorus in serum, calcium, phosphorus, deoxypyridinoline in urine, ash weight of bone, body weight and uterus weight were measured. Results : 1. The levels of fibula-tibial bone mineral density were significantly increased in comparison with OVX group at 8 weeks in Cervi Cornu group. 2. The levels of serum osteocalcin showed significant decrease in comparison with OVX group at 4 weeks in Cervi Cornu group. The levels of serum ALP and phosphorus showed significant decrease in comparison with OVX group at 4, 8 weeks in Cervi Cornu group group. The levels of serum calcium showed significant increase in comparison with OVX group at 4, 8 weeks in Cervi Cornu group. 3. The levels of urine calcium, phosphorus and deoxypyridinoline showed significant decrease in comparison with OVX group in Cervi Cornu group. 4. The levels of fibula-tibial ash weight showed significant increase in comparison with OVX group in Cervi Cornu group. 5. The levels of body weight were significantly decreased in comparison with OVX group at 4, 8 weeks in Cervi Cornu group. 6. The levels of uterus weight were significantly increased in comparison with OVX group in Cervi Cornu group. Conclusion : Reviewing these experimetal results, it appeared that Cervi Cornu had efficacy on treatment of osteoporosis.