The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)

The Society of Korean Medicine Obstetrics and Gynecology (대한한방부인과학회)
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Effects of Woogwiyeum on the Ovariectomized Rat Model of Postmenopausal Osteoporosis

우귀음(右歸飮)이 난소적출(卵巢摘出) 백서(白鼠)의 골다공증(骨多孔症)에 미치는 영향(影響)

  • Choe, Chang-Min (Department of Oriental Obstetric and Gynecology, college of Oriental Medicine, Wonkwang University) ;
  • Lee, Su-Jung (Department of Oriental Obstetric and Gynecology, college of Oriental Medicine, Wonkwang University) ;
  • Park, Kyung-Hwan (Department of Oriental Obstetric and Gynecology, college of Oriental Medicine, Wonkwang University) ;
  • Kim, Song-Baeg (Department of Oriental Obstetric and Gynecology, college of Oriental Medicine, Wonkwang University) ;
  • Cho, Han-Baek (Department of Oriental Obstetric and Gynecology, college of Oriental Medicine, Wonkwang University)
  • 최창민 (원광대학교 한의과대학 부인과학교실) ;
  • 이수정 (원광대학교 한의과대학 부인과학교실) ;
  • 박경환 (원광대학교 한의과대학 부인과학교실) ;
  • 김송백 (원광대학교 한의과대학 부인과학교실) ;
  • 조한백 (원광대학교 한의과대학 부인과학교실)
  • Published : 2006.11.30
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Abstract

Purpose : This study is to examine what are the effects of the Woogwiyeum(WGY) on the ovariectomized rat model of postmenopausal osteoporosis. Methods : We devide mice to 3 Group(Sham operated group, control group, WGY treated group) and analyze each serum component. Results : 1. Body weight in control group showed significant increase in comparison with sham, but that in WGY-treated showed no change in comparison with control. 2. The level of serum albumin, ALP in control group showed significant decrease in comparison with sham. That in WGY-treated was decreased in comparison with control. 3. Trabecular bone area as well as trabecular thickness in control group showed significant decrease in comparison with sham. Those in WGY-treated showed significant increase in comparison with control. 4. Osteoclast number and oseoblast surface in control group showed significant increase in comparison with sham. Those in WGY-treated showed significant decrease in comparison with control. Conclusion : WGY has shown to be capable of preventing and curing osteoporosis caused by old-aged and postmenopause.

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