• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.27 no.1
• /
• pp.9-16
• /
• 2014

Using a level set method and topological derivatives, a topological shape optimization method that is independent of an initial design is developed for linearly elastic structures. In the level set method, the initial domain is kept fixed and its boundary is represented by an implicit moving boundary embedded in the level set function, which facilitates to handle complicated topological shape changes. The "Hamilton-Jacobi(H-J)" equation and computationally robust numerical technique of "up-wind scheme" lead the initial implicit boundary to an optimal one according to the normal velocity field while minimizing the objective function of compliance and satisfying the constraint of allowable volume. Based on the asymptotic regularization concept, the topological derivative is considered as the limit of shape derivative as the radius of hole approaches to zero. The required velocity field to update the H-J equation is determined from the descent direction of Lagrangian derived from optimality conditions. It turns out that the initial holes are not required to get the optimal result since the developed method can create holes whenever and wherever necessary using indicators obtained from the topological derivatives. It is demonstrated that the proper choice of control parameters for nucleation is crucial for efficient optimization process.

• Journal of Radiation Protection and Research
• /
• v.31 no.3
• /
• pp.155-164
• /
• 2006

It is judged that there could be certainty in every process of analyzing environmental samples using Liquid Scintillation Counter. Therefore, this study focuses on quantitative evaluation on uncertainty in an effort to analyze comparatively accurately environmental samples. For this, after parameters which can have an effect on uncertainty was derived, the evaluation on each parameter was tamed out. The results of analysis of each parameter showed that the effect according to the weight difference of Teflon vial did not appear, and that standard deviations of SQP(E) averages reached saturation point at $75{\sim}90$ sec at the result of making increases step by step the irradiation time of External standard, and that values measured by repeat method produces good results compared with replicate. Also, conclusion was derived that analysis on sample after it is left in cold and dark room at least above 1,000 minutes have to be carried out, and the result of carrying out verification on results measured as well as equipment itself using radioactivity-error-analysis and chi-square test, resonable result was derived.

• Culinary science and hospitality research
• /
• v.21 no.5
• /
• pp.25-37
• /
• 2015

By studying the awareness level of students, for the need to protect personal information, and also by studying students' level of perception as to which information needs protection, this study aims to show that increased education is beneficial, and necessary, across all university majors. This increased education is necessary to improve information security, and increase the responsible sharing of private data which has many benefits, specifically in the Healthcare field. Utilizing student volunteers across multiple majors at a university in South Korea. These questionnaires measured the students' awareness of private information, their perception of private information and also the students' experience in receiving university level education regarding private information and the need for its protection. This study shows that, when compared to students in other fields, students in the field of public health had a higher level of awareness regarding the consequences of personal information disclosure for both public purposes and medical research. Within the parameters of this study, this outcome can be explained as the result of exposure to educational curriculum which contained information related to personal information protection. This increased education raised the student's awareness of which information is considered private, as well as, which information is valuable when responsibly shared. As a result, this study shows that an increase in education regarding information privacy, should be included in all university majors, and gives us evidence to support that this additional education is valuable to students at all levels and should be encouraged.

• Structural Engineering and Mechanics
• /
• v.55 no.4
• /
• pp.857-869
• /
• 2015

The aluminum 7075-T6 is known as an alloy widely used in aircraft structural applications, which does not exhibit strain rate sensitivity during dynamic compressive tests. Despite mechanical importance of the material, there is not enough attention to determine appropriate sample dimensions such as a sample diameter relative to the device bar diameter and sample length to diameter (L/D) ratio for dynamic tests and how these two parameters can change mechanical behaviors of the sample under dynamic loading condition. In this study, various samples which have different diameters of 31.8, 25.4, 15.9, and 9.5 mm and sample L/D ratios of 2.0, 1.5, 1.0, 0.5, and 0.25 were tested using Split Hopkinson Pressure Bar (SHPB), as this testing device is proper to characterize mechanical behaviors of solid materials at high strain rates. The mechanical behavior of this alloy was examined under ${\sim}200-5,500s^{-1}$ dynamic strain rate. Aluminum samples of 2.0, 1.5 and 1.0 of L/D ratios were well fitted into the stress-strain curve, Madison and Green's diagram, regardless of the sample diameters. Also, the 0.5 and 0.25 L/D ratio samples having the diameter of 31.8 and 25.4 mm followed the stress-strain curve. As results, larger samples (31.8 and 25.4 mm) in diameters followed the stress-strain curve regardless of the L/D ratios, whereas the 0.5 and 0.25 L/D ratios of small diameter sample (15.9 and 9.5 mm) did not follow the stress-strain diagram but significantly deviate from the diagram. Our results indicate that the L/D ratio is important determinant in stress-strain responses under the SHPB test when the sample diameter is small relative to the test bar diameter (31.8 mm), but when sample diameter is close to the bar diameter, L/D ratio does not significantly affect the stress-strain responses. This suggests that the areal mismatch (non-contact area of the testing bar) between the sample and the bar can misrepresent mechanical behaviors of the aluminum 7075-T6 at the dynamic loading condition.

• Tuberculosis and Respiratory Diseases
• /
• v.69 no.2
• /
• pp.103-107
• /
• 2010

Background: The aim of the present study was to evaluate whether findings on initial chest computed tomography (CT) of influenza pneumonia can help predict clinical outcome. Methods: We reviewed all adult patients admitted to the Emergency Department (ED) with a confirmed diagnosis of novel influenza A H1N1 virus (2009 H1N1) pneumonia, who underwent chest CT upon admission between Aug 26, 2009 and Jan 31, 2010. Radiologic findings were characterized by type and pattern of opacities and zonal distribution. Clinical outcome measures were intensive care unit (ICU) admission, mechanical ventilation, and inhospital death. Results: Of 59 patients diagnosed with 2009 H1N1 pneumonia, 41 (69.5%) underwent chest CT on admission into ED. Nine (22%) of these patients developed adverse clinical outcomes requiring the following treatments: 9 (22.0%) ICU admissions, 5 (12.2%) mechanical ventilation, and 3 (7.3%) inhospital deaths. Counting the number of patients with more than 4 involved lobes, the sensitivity, specificity, positive predictive value, and negative predictive value for detection of adverse clinical outcome were 67%, 84%, 55% and 80%, respectively. Conclusion: Extensive involvement of both lungs (over 4 lobes) is related to ICU admission, mechanical ventilation, and inhospital death. Initial chest CT may help predict an adverse clinical outcome of patients with 2009 H1N1 influenza pneumonia.

• Resources Recycling
• /
• v.29 no.3
• /
• pp.11-23
• /
• 2020

This study aims to investigate breakage and liberation characteristics of iron ore from Shinyemi mine, Jeongseon by ball mill. Parameters of breakage functions for three grade samples of iron ore were obtained using single-sized-feed breakage test and back-calculation based on nonlinear programming. The results showed that with the increase in the grade of iron ore, the breakage rate factor decrease whereas the particle size sensitivity decreases. This results from retardation of microcrack-propagation by magnetite grain in the ore. Breakage distribution analysis showed that the breakage mechanism appear to be impact fracture dominant with the increase of grade owing to the stress distribution effect by magnetite grain. Degree of liberation (DOL) increased with the increase in grade and decrease in particle size, respectively. Using the breakage function and size-DOL relationship, a model that can predict time-dependent-DOL is established. When scale-up factors from operating condition are available, the model is expected to be capable of predicting size and DOL with time in actual mining process.

• Journal of Pharmaceutical Investigation
• /
• v.38 no.2
• /
• pp.135-142
• /
• 2008

The present study describes the evaluation of the bioequivalence of two atorvastatin tablets, Lipitor $Tablet^{(R)}$ (Pfizer, reference drug) and Atorva $Tablet^{(R)}$ (Yuhan, test drug), according to the guidelines of Korea Food and Drug Administration (KFDA). Forty-nine healthy male Korean volunteers received each medicine at the atorvastatin dose of 40 mg in a $2{\times}2$ crossover study with a two weeks washout interval. After drug administration, serial blood samples were collected at a specific time interval from 0-48 hours. The plasma atorvastatin concentrations were monitored by an high performance liquid chromatography -tandem mass spectrometer (LC-MS/MS) employing electrospray ionization technique and operating in multiple reaction monitoring (MRM) and positive ion mode. The total chromatographic run time was 4.5 min and calibration curves were linear over the concentration range of 0.1-100 ng/mL for atorvastatin. The method was validated for selectivity, sensitivity, linearity, accuracy and precision. $AUC_t$ (the area under the plasma concentration-time curve from time zero to 48hr) was calculated by the linear log trapezoidal rule method. $C_{max}$ (maximum plasma drug concentration) and $T_{max}$ (time to reach $C_{max}$) were complied trom the plasma concentration-time data. Analysis of variance was carried out using logarithmically transformed $AUC_t$ and $C_{max}$. No significant sequence effect was found for all of the bioavailability parameters indicating that the crossover design was properly performed. The 90% confidence intervals of the $AUC_t$ ratio and the $C_{max}$ ratio for Atorva $Tablet^{(R)}$ / Lipitor $Tablet^{(R)}$ were ${\log}\;0.9413{\sim}{\log}\;1.0179$ and ${\log}\;0.831{\sim}{\log}\;1.0569$, respectively. These values were within the acceptable bioequivalence intervals of ${\log}\;0.8{\sim}{\log}\;1.25$. Based on these statistical considerations, it was concluded that the test drug, Atorva $Tablet^{(R)}$ was bioequivalent to the reference drug, Lipitor $Tablet^{(R)}$.

• Journal of Sensor Science and Technology
• /
• v.2 no.1
• /
• pp.81-86
• /
• 1993

Polycrystalline CdSe thin films were grown on ceramic substrate using a chemical bath deposition (CBD) method. They were annealed at various temperature and X-ray diffraction patterns were measured by X-ray diffractometer in order to study CdSe polycrystal structure. Using extrapolation method of X-ray diffraction patterns for the CdSe samples annealed in $N_{2}$ gas at $450^{\circ}C$ it was found hexagonal structure whose lattice parameters $a_{o}$ and $c_{o}$ were $4.302{\AA}$ and $7.014{\AA}$, respectively. Its grain size was about $0.3{\mu}m$. Hall effect on this sample was measured by Van der Pauw method and studied on carrier density and mobility depending on temperature. From Hall data, the mobility was likely to be decreased by piezo electric scattering at temperature range of 33 K and 200 K, and by polar optical scattering at temperature range of 200 K and 293 K. We measured also spectral response, sensitivity (${\gamma}$), maximum allowable power dissipation and response time on these samples.

• Journal of Satellite, Information and Communications
• /
• v.5 no.1
• /
• pp.58-62
• /
• 2010

This paper presents the effects of RF performance parameters on the Galileo receiver design via simulation after reviewing the requirements of the Galileo receiver structure. At first, we considered the general requirements, structure and characteristics of the Galileo system. Then we designed the Galileo receiver focused on performance requirement of 16 dB C/N which is equal to 15 % Error Vector Magnitude(EVM) by using Advanced Design System(ADS) simulation program. In order to verify the function of Automatic Gain Control(AGC)), we measured the IF output power level by changing the input power level at the front - end of the receiver. We analyzed the performance degradation due to phase noise variations of Local Oscillator(LO) in the Galileo receiver through EVM when the minimum sensitivity level of -127 dBm is applied at the receiver. We also analyzed the performance degradation according to variable Analog-to-Digital Converter(ADC) bits within the Dynamic range, -92 ~ -139 dBm, which has been defined by gain range (-2.5 ~ +42.5 dB) in the AGC operation. The results clearly show that the performance of the Galileo receiver can be improved by increasing ADC bits and reducing Phase Noise of LO.

• Journal of Soil and Groundwater Environment
• /
• v.9 no.4
• /
• pp.32-41
• /
• 2004

Analysis of water-level fluctuation due to goundwater-surface water interaction in coastal aquifers is carried out by numerical modeling. The conceptual model used in this study has a stream boundary and a tidal boundary that forms a right angle and the stream partially penetrates the aquifer. We analyzed the effect of each boundary and the simultaneous effect of the two boundary conditions. The area of influence caused by the stream boundary increased during the simulation, while the influence zone of the coastal boundary was relatively constant. The groundwater level near the zone where two boundaries meet may rise by the action of combined effect of the two boundaries or may not change by cancelling the effect of each boundary. Thereafter, care must be taken when hydraulic parameters are estimated using sinusoidal oscillations of hydraulic head in coastal aquifers. Sensitivity analysis is employed to develop insight into the controls on groundwater level fluctuations. In this study our analyses focused on the effect of conductance and the stream width to the aquifer nearby.