• Title/Summary/Keyword: Parameters Sensitivity

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Sensitivity Analysis of Amino Acids in Simulated Moving Bed Chromatography

  • Lee, Ju-Weon;Lee, Chong-Ho;Koo, Yoon-Mo
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.11 no.2
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    • pp.110-115
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    • 2006
  • We conducted a sensitivity analysis of the simulated moving bed (SMB) chromatography with the case model of the separation of two amino acids phenylalanine and tryptophan. We consider a four-zone SMB chromatography where the triangle theory is used to determine the operating conditions. Competitive Langmuir isotherm model was used to determine the adsorption isotherm. The finite difference method is used to solve nonlinear partial differential equation (PDE) systems numerically. We examined the effects of alterations in the operating conditions(feed-extract, feed-raffinate, eluent-extract, eluent-raffinate, recycle, and switching time) and the adsorption isotherm parameters (Langmuir isotherm parameters a and b) on SMB efficiency. The variation range of operating conditions and Langmuir isotherm a was between -50 and 50% of original value and the variation range of the Langmuir isotherm b was between $2.25^{-5}$ and $2.25^5$ times of original value.

Dynamic Parameter Analysis of Bolted Joint (체결력에 따른 볼트결합부의 동적 파라미터 해석)

  • Baek, Sung-Nam;Ji, Tae-Han;Park, Young-Pil
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.20 no.1
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    • pp.53-67
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    • 1996
  • The dynamic characteristics of mechanical structure are strongly affected by the properties of joint parameters. In this study, the test structures are constructed with two beams which are clamped by bolts, and a bolted joint which is modelled as a lumped stiffness element. To idientify the dynamic joint parameters with variance of clamping torque of bolts, the sensitivity analysis and the mode energy analysis methods are investigated experimentally. As a reult of these two methods, stiffnesses of bolted joint are experimentally found to increase as the clamping torque increases. These stiffnesses identified from the sensitivity analysis and the mode energy analysis method have some difference.

Efficient Response Surface Modeling using Sensitivity (민감도를 이용한 효율적인 반응표면모델생성)

  • Wang, Se-Myung;Kim, Chwa-Il
    • Proceedings of the KSME Conference
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    • 2003.11a
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    • pp.1882-1887
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    • 2003
  • The response surface method (RSM) became one of famous meta modeling techniques, however its approximation errors give designers several restrictions. Classical RSM uses the least squares method (LSM) to find the best fitting approximation models from the all given data. This paper discusses how to construct RSM efficiently and accurately using moving least squares method (MLSM) with sensitivity information. In this method, several parameters should be determined during the construction of RSM. Parametric study and optimization for these parameters are performed. Several difficulties during approximation processes are described and numerical examples are demonstrated to verify the efficiency of this method.

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Three-Dimensional Modelling and Sensitivity Analysis for the Stability Assessment of Deep Underground Repository

  • Kwon, S.;Park, J.H.;Park, J.W.;Kang, C.H.
    • Nuclear Engineering and Technology
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    • v.33 no.6
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    • pp.605-618
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    • 2001
  • For the mechanical stability assessment of a deep underground high-level waste repository. computer simulations using FLAC3D were carried out and important parameters including stress ratio, depth, tunnel size, joint spacing, and joint properties were chosen from sensitivity analysis. The main effect as well as the interaction effect between the important parameters could be investigated effectively using fractional factorial design . In order to analyze the stability of the disposal tunnel and deposition hole in a discontinuous rock mass, different modelings were performed under different conditions using 3DEC and the influence of joint distribution and properties, rock properties and stress ratio could be determined. From the three dimensional modelings, it was concluded that the conceptual repository design was mechanically stable even in a discontinuous rock mass.

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A Study on the Sensitivity of Influencing Parameters on Axial Force in CWR on a Viaduct (교량상 장대레일의 축력 영향인자의 민감도 분석에 관한 연구)

  • Chun, Hee-Kwang;Choi, Jin-Yu;Choi, Il-Yun;Yang, Shin-Chu;Jeong, Jang-Yong
    • Proceedings of the KSR Conference
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    • 2008.11b
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    • pp.1043-1049
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    • 2008
  • Trouble by excessive axial stress in CWR layed on a bridge is frequently happen, and this problem is induced from lack of considering on the track/structure interface on preliminary design stage. In this study, the sensitivity evaluation for the major influencing parameters, that is, expansion length of span, stiffness of super structure, arrangement of bearing, and strength of sub-structure, to the axial force in CWR on a bridge is conducted. From the sensitivity study, the guideline to reduce axial force efficiently in CWR for bridge engineer was suggested. The suggested guideline may not applicable for every case, but it is helpful for preliminary design of bridge.

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Effects of Digital Elevation Model in Water Quality Modeling using Geogrpahic Information System

  • Cho, Sung-Min
    • International Journal of Internet, Broadcasting and Communication
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    • v.13 no.2
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    • pp.14-19
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    • 2021
  • Aim of this research was to investigate the effects of Digital Elevation Model (DEM) for sensitivity analysis with two types of DEMs: 1 to 24,000 and 1 to 250,000 DEM. Another emphasis was given to the development of methodology for processing DEMs to create ArcGIS Pro and GRASS layers. This was done while developing water quality system modeling using DEMs which were used to model hydrological processes and SWAT model. Sensitivity analysis with DEMs resulted in different runoff volumes in the model simulation. Runoff volume was higher for the 1:24,000 DEM than 1:250,000 DEM, probably due to the finer resolution and slope which increased the estimated runoff from the watershed. Certainly the DEMs were factors in precision of the simulations and it was obvious during sensitivity analysis that DEMs had significant effect on runoff volumes. We suggest, however, that additional comparative research could be conducted involving more parameters such as soil and hydrologic parameters to provide insight into the overall physical system which the SWAT model represents.

Structural damage detection based on changes of wavelet transform coefficients of correlation functions

  • Sadeghian, Mohsen;Esfandiari, Akbar;Fadavie Manochehr
    • Structural Monitoring and Maintenance
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    • v.9 no.2
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    • pp.157-177
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    • 2022
  • In this paper, an innovative finite element updating method is presented based on the variation wavelet transform coefficients of Auto/cross-correlations function (WTCF). The Quasi-linear sensitivity of the wavelet coefficients of the WTCF concerning the structural parameters is evaluated based on incomplete measured structural responses. The proposed algorithm is used to estimate the structural parameters of truss and plate models. By the solution of the sensitivity equation through the least-squares method, the finite element model of the structure is updated for estimation of the location and severity of structural damages simultaneously. Several damage scenarios have been considered for the studied structure. The parameter estimation results prove the high accuracy of the method considering measurement and mass modeling errors.

The Senstivitiy Analysis and Optimiaztion for the Development of the SMD Performance (표면 실장기(SMD) 성능 개선을 위한 민감도 해석 및 최적화)

  • Cha, In-Hyuk;Han, Chang-Soo;Kim, Jung-Duck
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1996.04a
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    • pp.568-573
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    • 1996
  • In this paper, A design strategy of the Surface Mounting Device for accurate and better performance is studied. Analytical Modeling. Sensitivity analysis and optimization are being conducted. The ANSYS software and experimental method are used for verification of the analytical equations withboundary conditons. Through the sensitivity analysis, the most dominant design parameters can be detected. The optimum design parameters for performing given performing given perfomances are selected by using the optimization algorithm. The design tool based on the design strategy for the analysis, modeling and optimization will be useful for a re-design and better perofrmance of the SMD.

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A study on a capacitive displacement sensor for the ultraprecision measurement (초정밀 측정용 정전용량 변위센서에 관한 연구)

  • Ahn, Hyeongjoon;Chang, Inbae;Han, Dongchul
    • Journal of the Korean Society for Precision Engineering
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    • v.14 no.11
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    • pp.110-117
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    • 1997
  • This paper discusses numerically and experimenally several design parameters for the plate- type capacitive displacement sensor. The influenences of shape of this sensor on the sensitivity are numerically analyzed with the charge density method. Using many test sensor plates of different shape for verifing the validity of this method can not guarantee the repetibility of experiments. Therefore we made specially the test sensor plate so that experiments of effects of shape of this sensor on sensitivity can be done with only that plate. Results from these experiments agree well with those from numerical analysis.

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Probabilistic structural damage detection approaches based on structural dynamic response moments

  • Lei, Ying;Yang, Ning;Xia, Dandan
    • Smart Structures and Systems
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    • v.20 no.2
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    • pp.207-217
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    • 2017
  • Because of the inevitable uncertainties such as structural parameters, external excitations and measurement noises, the effects of uncertainties should be taken into consideration in structural damage detection. In this paper, two probabilistic structural damage detection approaches are proposed to account for the underlying uncertainties in structural parameters and external excitation. The first approach adopts the statistical moment-based structural damage detection (SMBDD) algorithm together with the sensitivity analysis of the damage vector to the uncertain parameters. The approach takes the advantage of the strength SMBDD, so it is robust to measurement noise. However, it requests the number of measured responses is not less than that of unknown structural parameters. To reduce the number of measurements requested by the SMBDD algorithm, another probabilistic structural damage detection approach is proposed. It is based on the integration of structural damage detection using temporal moments in each time segment of measured response time history with the sensitivity analysis of the damage vector to the uncertain parameters. In both approaches, probability distribution of damage vector is estimated from those of uncertain parameters based on stochastic finite element model updating and probabilistic propagation. By comparing the two probability distribution characteristics for the undamaged and damaged models, probability of damage existence and damage extent at structural element level can be detected. Some numerical examples are used to demonstrate the performances of the two proposed approaches, respectively.