• Structural Engineering and Mechanics
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• v.51 no.2
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• pp.299-313
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• 2014

In the first part of this paper, the influences of some of crack parameters on natural frequencies of a cracked cantilever Functionally Graded Beam (FGB) are studied. A cantilever beam is modeled using Finite Element Method (FEM) and its natural frequencies are obtained for different conditions of cracks. Then effect of variation of depth and location of cracks on natural frequencies of FGB with single and multiple cracks are investigated. In the second part, two Multi-Layer Feed Forward (MLFF) Artificial Neural Networks (ANNs) are designed for prediction of FGB's Cracks' location and depth. Particle Swarm Optimization (PSO) and Back-Error Propagation (BEP) algorithms are applied for training ANNs. The accuracy of two training methods' results are investigated.

• Journal of Magnetics
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• v.19 no.3
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• pp.266-272
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• 2014

In this paper, we suggest reliability as a metric to evaluate the robustness of a design for the optimal design of electromagnetic devices, with respect to constraints under the uncertainties in design variables. For fast numerical efficiency, we applied the sensitivity-assisted Monte Carlo simulation (S-MCS) method to perform reliability calculation. Furthermore, we incorporated the S-MCS with single-objective and multi-objective particle swarm optimization algorithms to achieve reliability-based optimal designs, undertaking probabilistic constraint and multi-objective optimization approaches, respectively. We validated the performance of the developed optimization algorithms through application to the optimal design of a superconducting magnetic energy storage system.

• YAKHAK HOEJI
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• v.59 no.4
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• pp.151-157
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• 2015

The purpose of this study is to demonstrate how lead compounds are best optimized with the application of in silico QSAR and PBPK modeling at the early drug discovery stage. Several predictive QSAR models such as $IC_{50}$ potency model, intrinsic clearance model and brain penetration model were built and applied to a set of virtually synthesized library of the BACE1 inhibitors. Selected candidate compounds were also applied to the PBPK modeling for comparison between the predicted animal pharmacokinetic parameters and the observed ones in vivo. This novel lead optimization strategy using QSAR and PBPK modelings could be helpful to expedite the drug discovery process.

• Proceedings of the SAREK Conference
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• 2009.06a
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• pp.415-420
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• 2009

Selective Catalytic Reduction(SCR) has been used for the reduction of $NO_x$ in a steam supply boiler. Recently, the reduction of $NO_x$ becomes an important research field because of its negative effect on an environment. Shape optimization of circular poles installed in the chamber, which is located in upstream of a SCR, has been performed using response surface method and three-dimensional Navier-Stokes analysis to enhance gas flow uniformity. Three design parameters, diameter, arranging angle and stretching ratio of circular poles, are considered in the present study. Throughout the shape optimization of a circular pole, gas flow uniformity is successfully increased by decreasing local recirculation flow in a square duct chamber. Recirculation flow observed in the corner of the square duct can be reduced by proper installation of a guide vane or a blunt body. Detailed flow characteristics are also analyzed and discussed.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2004.05a
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• pp.195-199
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• 2004

Recently, optical disc drives are required to have high density and capacity in according with development of high definition images and rapid increase of various informations. Consequently, the numerical aperture becomes larger, the wavelength of laser is coming to be short. However, it deteriorates rolling mode effect on an optical pickup actuator. Therefore, this paper proposes new design and optimization of tracking coils for reducing it. First, we verify that discord between the center of force and the center of mass by restrictions of design condition is an important factor of rolling mode effect. Then, in order to reduce it, we propose new design parameters of tracking coils. Finally, we reduce rolling mode effect through optimization of tracking coils using Taguchi method and response surface method.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2012.04a
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• pp.157-162
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• 2012

A structural modification of baseframe is an effective method to avoid resonance in marine diesel generator (D/G) set which consists of diesel engine, generator and baseframe. However the reinforcement with thick plates or additional parts to increase the natural frequency can be less effective because of increased weight. Especially fine control of target mode based on the experience is difficult because the weight and interference of system have to be considered. In this paper, the design optimization of baseframe was performed to reduce the resonant vibration using a gradient descent method. The design parameters such as thickness, shape and location of baseframe parts are optimized to increase the torsional natural frequency of D/G set. From the actual test, the new designed baseframe reduced the vibration level in resonance by 55% without any increase of weight and interference. interference.

• Journal of Electrical Engineering and Technology
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• v.10 no.3
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• pp.965-970
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• 2015

This paper uses response surface methodology as the optimization method of torque of multi-DOF deflection type PM motor. Firstly, the application of Taguchi algorithm selects structural parameters affecting the motor torque largely which simplifies the optimization process greatly. Then, based on the central composite design (CCD), response surface equation numerical model is constructed by the finite element method. With the aid of experiment design and analysis software, the effects of the interaction among factors on the index are analyzed. The results show that the analytical method is efficient and reliable and the experimental results can be predicted by response surface functions.

• Journal of the Korean Society of Safety
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• v.31 no.6
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• pp.39-44
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• 2016

Suitable design and operation of distillation process is very dependent on vapor-liquid equilibrium calculation. The usual calculation method is use binary interaction parameter. Flash points of n-propanol+n-butanol and 2-butanol+n-butanol were measured by Seta-flash closed cup tester. Experimental Flash points were compared with those calculated by the method based on Raoult's law and the optimization method using Wilson equation. The binary interaction parameters obtained by the optimization method are then used to calculate the bubble points of n-propanol+n-butanol and 2-butanol+n-butanol.

• Journal of Korean Society for Quality Management
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• v.27 no.2
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• pp.237-250
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• 1999

Response surface analysis has been a popular tool conducted by engineers in many processes. In this paper, response surface function, named partial least squares response surface function is proposed. Partial least squares response surface function is a function of partial least squares components and the response surface modeling is used in either a first-order or a second-order model. Also, this approach will have the engineers be able to do the response surface modeling and the process optimization even when the number of experimental runs is less than the number of model parameters. This idea is applied to the nondesign data and an application of partial least squares response surface function to the process optimization is considered.

• Proceeding of EDISON Challenge
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• 2015.03a
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• pp.500-509
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• 2015

This paper presents the single objective design optimization of plate-fin heat sink equipped with fan cooling system using Genetic Algorithm. The proper heat sink and fan model are selected based on the previous studies. And the thermal resistance of heat sinks and fan efficiency during operation are calculated according to specific design parameters. The objective function is combination of thermal resistance and fan efficiency which have been taken to measure the performance of the heat sink. And Decision making procedure is suggested considering life time of semiconductor and Fan Operating cost. And also Analytical Model used for optimization is validated by Fluent, Ansys 13.0 and this model give a quite reasonable and reliable design.