• Food Science and Biotechnology
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• v.17 no.2
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• pp.219-227
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• 2008

Bacillus thuringiensis was isolated as a pathogen of the sotto disease of silkmoth larvae about a hundred years ago. Since then, this bacterium has attracted attentions of not only insect pathologists but also many other scientists who are interested in its strong and specific insecticidal activity. This has led to the recent worldwide development of B. thuringiensis-based microbial insecticides and insect-resistant transgenic plants, as well as a landmark discovery of par asp orin, a cancer cell-specific cytotoxin produced by B. thuringiensis. In this review, we describe examination of interaction between inclusion proteins of B. thuringiensis and brush border membrane of insects using a surface plasmon resonance-based biosensor, identification and characterization of parasporin-4, the latest parasporin produced by the B. thuringiensis A1470 strain, and an effective method for preparing the parasporin-4 from inclusion bodies expressed in the recombinant Escherichia coli cells.

• Bulletin of the Korean Chemical Society
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• v.21 no.4
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• pp.383-388
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• 2000

Multiblock copolymers consisting of poly( g-benzyl L-glutamate) (PBLG) as the hydrophobic part and poly(ethylene oxide) (PEO) as the hydrophilic part (GEG) were synthesized and characterized. GEG polymeric micelles were prepared by the dialysis technique. Particle size distributions based on intensity,volume, and number-average were 22.6 $\pm$ 11.9 nm, 23.5 $\pm$ 4.6 nm, and 23.7 $\pm$ 37 nm, respectively. It was observed that par-ticle size and size distribution of GEG polymeric micelles changed significantly with the choice of initial sol-vent. Transmission electron micrographs (TEM) showed the polymeric micelles to be spherically shaped, with sizes ranging from 20 nm to 40 nm in diameter. Fluorescence spectroscopy measurements suggested that GEG block copolymers wereassociated in water to form polymeric micelles, and the critical micelle concentrations (CMC) value of the block copolymers was 0.0094 g/L. Further evidenceof micelle formation of GEG block copolymers and limited mobility of the PBLG chain in the core ohe micelle was obtained with 1 H NMR in D2O.

• Journal of Oral Medicine and Pain
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• v.11 no.1
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• pp.67-78
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• 1986

This study was attempted to identify the emotional characteristics of temporomandibular disorder patients. The author applied one of the self-report modes of psychological measurement, Symptom Chechlist-90-Revision. The subjects were 219 TM disorder patients who visited the Department of Oral Diagnosis and Oral Medicine, Seoul National University Hospital during the period from December 1985 to September 1986. All the patients were divided into subgroup according sex, age, duration of symptoms, presence or absence of T-scores of each symptom dimension and global index. The obtained result were as follows : 1. Mean value of T-scores of each symptom dimension and global of the overall patients was within normal range. The two higher mean values of T-scores among 9 symptom dimensions were those of SOM and ANX. 2. Mean values of T-scores of females were higher than those of males in the O-C, DEP, ANX, HOS, PSY dimensions and all global indices, and there was a significant difference in the distribution of T-scores of the SOM dimension between males and female(P<0.05). 3. There was no significant difference between the subgroup under 30 years and the subgroup 30 years or older. 4. The subgroup with symptoms for 6 months or longer showed the higher mean values of T-scorers in the SOM, O-C, I-S, DEP, ANX, PHOB, PAR, PSY dimensions and all global indices compared with the subgroup with symptoms for shorter than 6 months. 5. The subgroup with pain showed the higher mean values of T-scores in all the symptom dimensions except the PAR in comparison with the subgroup with other complaints than pain, and there was a significant difference in the distribution of T-scores of the PST index between the pain subgroup and the non-pain subgroup(P<0.05). There was a significant difference in the distribution of T-scores of the PHOB dimension between the high-school graduates subgroup and the college graduates subgroup(P<0.05).

• Journal of Korean society of Dental Hygiene
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• v.12 no.1
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• pp.37-46
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• 2012

Objectives : This research was investigated to evaluate the psychological characteristics and changes of psychological state among dental orthodontic patients. Methods : This cross-sectional questionnaire research was conducted with 230 dental orthodontic patients in Busan from December 23, 2009 to March 6, 2010. The psychological analysis of dental orthodontic treatment patients was performed with Symptom checklist-90-revision(SCL-90-R) considering 5 general characteristics and 2 treatment period related characteristics. Estimated psychological results were changed T-score. Data analysis was performed with descriptive analysis, t-test and ANOVA using SAS(ver 9.1) program. Results : The levels of T-score of SCL-90-R were $43.88{\pm}7.50$ in hostility(HOS), $43.38{\pm}4.64$ in phobic anxiety(PHOB), $43.20{\pm}6.24$ in somatization(SOM), $42.13{\pm}6.71$ in paranoid ideation(PAR), $41.39{\pm}8.16$ in interpersonal sensitive(I-S), $41.01{\pm}7.90$ in obsessive-compulsive(O-C), $40.96{\pm}5.37$ in psychoticism(PSY), $40.96{\pm}5.19$ in anxiety(ANX) and $39.81{\pm}6.80$ in depression(DEP), respectively. The T-score of phobic anxiety in before treatment group was higher than that of treatment groups. The T-score of interpersonal sensitive and paranoid ideation in over 36 months treatment period group were higher than that of other treatment period groups. Conclusions : Phobic anxiety(PHOB), interpersonal sensitive(I-S) and paranoid ideation(PAR) were affected in pre-treatment and long-term treatment dental orthodontic patients. Psychological management methods considering treatment period are needed to improve mental health of dental orthodontic patients.

• Analytical Science and Technology
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• v.6 no.1
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• pp.121-129
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• 1993

UV/VIS spectrophotometer interfaced with HPIC(High Performance Ion Chromatography) has been applied to the determination of lanthanide elements. The separation of lanthanide elements with HPIC helped to avoid erroneous analytical results due to interferences. Individual lanthanide elements at ppm level were separated on a HPIC CS5 column using pyromellitic acid and oxalic acid. The individual lanthanide elements were detected at 520nm following post-column reaction with PAR. Sm, Eu, Gd, Y, Tb, Dy, Ho, Er, Tm, Tb, and Lu were separated by pyromellitic acid. La, Ce, Pr and Nd were separated by oxalic acid. Appropriate pH of pyromellitic acid for separation was at pH 2.99.

• The Transactions of the Korea Information Processing Society
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• v.4 no.10
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• pp.2544-2552
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• 1997

This paper presents three multiprocess models for parallel protocol implementation, that is, (1)channel communication model, (2)fork-join model, and (3)event polling model. For the specification of parallelism for each model, a parallel programming language, Par. C System, is used. to measure the performance of multiprocess models, we implemented the Internet Protocol Suite(IPS) Internet Protocol (IP) for each model by writing the parallel language on the Transputer. After decomposing the IP functions into two parts, that is, the sending side and the receiving side, the parallelism in both sides is exploited in the form of Multiple Instruction Single Data (MISD). Three models are evaluated and compared on the basis of various run-time overheads, such as an event sending via channels in the parallel channel communication model, process creating in the fork-join model and context switching in the event polling model, at the sending side and the receiving side. The event polling model has lower processing delays as about 77% and 9% in comparison with the channel communication model and the fork-join model at the sending side, respectively. At the receiving side, the fork-join model has lower processing delays as about 55% and 107% in comparison with the channel communication model and the event polling model, respectively.

• Journal of Radiation Protection and Research
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• v.2 no.1
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• pp.24-30
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• 1977

Les eaux de $g\'{e}n\'{e}rateur$ de vapeur d'un $r\'{e}acteur$ P. W. R peuvent $\^{e}tre$ $contamin\'{e}es$ par des $radio-\'{e}lements$. Ces eaux sont habituellement $condition\'{e}es$ 'phosphate' pour limiter leur $agressivit\'{e}$ et la tendence actuelle est de remplacer les phosphate par un conditionment 'Amoniaques'. La $pr\'{e}sente$ $\'{e}tude$ a pour but de definir la $possibilit\'{e}$ $d'{\'{e}}purer$ des eaux $condition\'{e}es$ $\'{a}$ l'ammoniaque $\'{a}$ l'aide $d'{\'{e}}changeurs$ d'ion organiques. Des Facteurs de $D\'{e}contamination$ (F. D) en Cesium 137 et Strontium 90 et la $dur\'{e}e$ du cycle $d'{\'{e}}puration$ ont $d\^{u}$ $\^{e}tre$ bien meilleurs avec une colonne de 10 ml de $r\'{e}sine$ Carborylique Duolite $CC_4$ mise sous forme acide, suivie d'une colonne de 10 ml de $r\'{e}sine$ cationique Amberlite IR 120 mise sous forme acide et suivie d'une colonne de 10 ml de $r\'{e}sine$ anionique Amberlite IRA 400 mise sous forme hydroxyde.

• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.464-464
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• 2018

최근 풍수해 현황 분석(국민안전처, 2016)에서는 2003년 이후 태풍 루사와 매미와 같은 대형태풍이 최근에 발생하지 않아 대부분 하천급류로 인한 인명피해가 대부분이라고 언급하였다. 최근 풍수해로 인한 피해가 발생하지는 않았지만 호우/태풍이 발생할 경우 인명보호와 불편해소를 최우선에 두고 각종 정책들을 선제적으로 추진하고 있어 홍수범람발생 예상지역에 대한 인명피해 분석은 반드시 필요하다고 판단된다. 최근들어 인명피해를 평가하는 기술은 피해자료로부터 비교적 간단히 분석되는 경험적 방법에서 2차원 동적 수리모형과 연계, 그리고 정밀한 인구, 건물 등의 자료를 활용하여 대피율, 사전경보 등 인명피해에 영향을 미치는 다양한 요소를 복합적으로 고려하고 개념적이고 기계적 방법으로 발전하는 추세이다. 우리나라의 경우 인명피해 평가와 관련한 연구사례가 거의 전무한 상태이고, 치수경제성분석에서 제시하는 침수면적에 기반한 간략한 방법만이 실무에서 활용되고 있다. 최근 국외에서 제시한 접근방법은 본 연구에서의 개발하고자 하는 목적과 방향에 부합하지 않다고 판단되며, 국내 실정을 고려할 때 주요 영향인자를 추가하고, 특히 노출인구, 인명 인벤토리의 해상도를 높이는 데 주안점을 두고자 한다. 홍수로 인한 인명피해 발생확률은 사후분석의 일환으로 침수흔적도를 통해 총 2개의 침수구간을 설정한 후 Census data를 활용한 위험인구(Population at Risk, PAR)를 산정한후, NDMS 인명피해 자료를 활용하여 침수구간별 인명피해 발생확률을 제시하였다. 여기서 제시한 침수구간의 경우 데이터의 축적정도에 따라 구간을 세밀화 할 수 있는데, 본 연구에서는 총 2개구간(0-1m, 1m 이상)으로 계략화 하여 제시하였다. 본 연구에서는 4개의 지자체의 인명피해 자료를 통해 인명피해 발생확률을 산정하였으며, 해당내용을 시범유역의 빈도별 침수구역도에 적용하여 인명피해 발생을 분석하였다. 해당 연구결과의 경우 인명피해에 대한 명확한 결과를 유추하는데에는 한계가 있지만, 인명피해에 기반한 해당지역의 장래피해규모를 예측하는 데에는 기초가 될 수 있을 것으로 판단된다.

• Journal of Advanced Navigation Technology
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• v.26 no.5
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• pp.272-280
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• 2022

An aircraft carrier is a combat ship that acts as an aircraft base at sea and performs combat through aircraft mounted as a military ship operating the aircraft. The Navy proposed a 40,000-ton light aircraft carrier operation plan that could be equipped with vertical takeoff and landing fighter jets and helicopters around 2033, and based on this, this study examined the operation of aircraft control equipment among the aviation support systems required for operating light aircraft carriers in Korea. PriFly, TWR's ILARTS, ILM for airspace control, ASR, PAR, LAAS or RNAV, PALS (JPALS) for access control are required as essential equipment, and communication network and SCATT-16 are required along with URN-25 TACAN, ICLS (El/Az), ACLS OLS, MOVAS, IFLOLS, etc. This study consists of two parts, and part 2 will describe a specific control method on an aircraft carrier.

• International Journal of Oncology
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• v.56 no.2
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• pp.630-640
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• 2020

Plant flavonoid 2',3,4',5,7-pentahydroxyflavone (morin hydrate), isolated from the family Moraceae (Morus alba L.), is known to have anti-inflammatory and anticancer effects. However, its pharmaceutical effects on metastasis have not been fully elucidated to date. Therefore, the current study investigated the effects of morin hydrate on cancer metastasis in MCF-7 human breast cancer cells. The results showed that morin hydrate suppressed 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cell migration and invasion via the inhibition of matrix metalloproteinase (MMP)-9 activity. Furthermore, gene expression level of MMP-9, MMP-7, urokinase plasminogen activator (uPA), uPA receptor (uPAR) and fibronectin were significantly decreased by morin hydrate treatment. Morin hydrate inhibited the phosphorylation of Akt and glycogen synthase kinase (GSK)-3β, and downregulated the expression of an activator protein-1 subunit c-Fos. In addition, the GSK-3β phosphorylation and c-Fos expression were suppressed by PI3K/Akt pathway inhibitors, LY294002 and wortmannin. Taken together, these results demonstrated that morin hydrate reduced the metastatic potential in TPA-treated MCF-7 human breast cancer cells via the inhibition of MMPs, uPA and uPAR, and the underlying Akt/GSK-3β/c-Fos pathway. Therefore, the present investigation suggested that morin hydrate may be a natural substance with a preventive potential for metastasis in breast cancer cells.