• 대한한의학방제학회지
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• 제31권1호
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• pp.21-28
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• 2023

Objective : Scolopendra, a dried body of Scolopendra subspinipes mutilans, is one of Korean medicine. Several reports revealed that Scolopendra has therapeutic effects for arthritis, neuroinflammatory diseases and neuropathic pain. However, the fetal adaptive response or teratogenicity associated with administration of Scolopendra is unclear. Therefore, this study aimed to investigate the fetal toxicity effects that were induced following oral administration of Scolopendra water extract (SWE) in pregnant mice. Methods : The pregnant mice were administrated SWE at dosed of 0, 100, 500 and 1000 mg/kg/day during gestation day 0-18. The mortality, body weight and clinical signs of pregnant mice were observed throughout experimental period. Also, the mortality and malformations in foetus were examined. Results : No meaningful changes were observed in the mortality and clinical signs of pregnant mice between the normal control group and SWE administrated groups. Additionally, there are no significant changes in fetal mortalities, and malformations by SWE administration. conclusion : These results suggest that oral exposure to SWE during pregnancy at oral dosages up to 1000 mg/kg/day did not induce teratogenic toxicity in regard to fetal mortality and morphology.

• 동의생리병리학회지
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• 제36권6호
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• pp.213-220
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• 2022

We investigated the current status of research using extracorporeal shock waves on the basis of meridian and acupoint theory. By March 2022, five foreign databases (CAJ, Pubmed, Web of Science, EMBASE, Cochrane Library) and six Korean databases (Dbpia, RISS, KMBASE, scienceON, KISS, NDSL) were searched with the terms using 'Extracorporeal shock wave' and '(Acupoint or Acupuncture point)'. The search terms were adapted according to the language of the database. There were no restrictions on the study design. As a result of the search, twenty-seven papers were selected for analysis. One study was searched in English database, and the remaining twenty-six studies were searched in Chinese database. There were nineteen pain-related diseases, four obsterics and gynecology diseases, two bone-related diseases, and two other diseases. The most frequently used acupoints were GB34, ST36, and KI3. A total of six adverse events were reported in five papers. The use of extracorporeal shock wave on the basis of meridian and acupoint theory is considered to have sufficient meaning in Korean Medicine. It is expected to use extracorporeal shock wave as a new treatment method for Korean Medicine doctors in the near future.

• Journal of Trauma and Injury
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• 제35권4호
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• pp.291-296
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• 2022

The therapeutic approach for colon injury has changed continuously with the evolution of management strategies for trauma patients. In general, immediate laparotomy can be considered in hemodynamically unstable patients with positive findings on extended focused assessment with sonography for trauma. However, in the case of hemodynamically stable patients, an additional evaluation like computed tomography (CT) is required. Surgical treatment is often required if prominent mesenteric extravasation, free fluid, bowel infarction, and/or colon wall perforation are observed. However, immediate intervention in hemodynamically stable patients without indications for surgical treatment remains questionable. Three patients with colon and mesocolon injuries caused by blunt trauma were treated by nonoperative management. At the time of admission, they were alert and their vital signs were stable. Colon and mesocolon injuries, large hematoma, colon wall edema, and/or ischemia were revealed on CT. However, no prominent mesenteric extravasation, free fluid, bowel infarction, and/or colon wall perforation were observed. In two cases, conservative treatment was performed without worsening abdominal pain or laboratory tests. Follow-up CT showed improvement without additional treatment. In the third case, follow-up CT and percutaneous drainage were performed in considering the persistent left abdominal discomfort, fever, and elevated inflammatory markers of the patient. After that, outpatient CT showed improvement of the hematoma. In conclusion, nonoperative management can be considered as a therapeutic option for mesocolon and colon injuries caused by blunt trauma of selected cases, despite the presence of large hematoma and ischemia, if there are no clear indications for immediate intervention.

• 대한족부족관절학회지
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• 제26권4호
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• pp.183-186
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• 2022

Anterior tibialis ruptures are a rare type of injury related to the foot and ankle. Specifically, chronic and non-traumatic ruptures are related to preexisting chronic tendinopathic conditions and anatomical factors. These ruptures may cause persistent pain and functional impairments if neglected. Chronic tibialis anterior ruptures are frequently diagnosed late because the symptoms are not distinct. In cases with chronic or non-traumatic tibialis anterior tendon ruptures, tendons often become irreparable. Hence, various surgical options have been introduced to address this issue. The current surgical treatment options are as follows: free sliding anterior tibialis graft, extensor hallucis longus tendon transfer, and reconstruction with an allograft tendon. To date, there have been few reports about the reconstruction technique using Z-plasty for irreparable tibialis anterior tendon ruptures. In this report, we present a rare case of the application of the tibialis anterior tendon reconstruction technique using Z-plasty and tenodesis for a middle-aged man with an irreparable avulsion injury rupture. We also present the management plan and prognostic outlook, as well as a subsequent review of the relevant literature.

• 한국의류산업학회지
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• 제25권2호
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• pp.221-229
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• 2023

This study aims to develop knee protectors that provide high safety and fitness, while incorporating a motion-adaptable 3D-printed pad. These protectors were evaluated by individuals who experience knee discomfort or pain. The results are as follows. First, the 3Dprinted pad design of a hexagonal mesh structure, which is modeled for excellent appearance and knee movement. Each unit of the mesh has a outer layer of 2mm thick, a spacer layer of 1 mm in diameter, and is connected by a 1.5 mm bridge. The bridge was extended up to 1.2 cm. Second, the knee brace was designed in three types - cylinder, strap, and combination by Universal design. Impact protection measurements of the three knee protectors demonstrated roughly 80% reduction in impact. Third, based on usability evaluation, cylinder type protectors have the highest ratings in most areas, primarily because of their ease of use. The strap type protector received positive reviews in terms of appearance and care, and the combination type provided stable knee protection. This study demonstrated the potential industrial application of 3D printing technology by designing and evaluating protective products for the human body. The results of this study are expected to aid knee protector manufacturers in developing practical products and promoting the development of protective equipment for other body parts or purposes.

• Journal of Acupuncture Research
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• 제40권2호
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• pp.111-128
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• 2023

Trigger finger is a common cause of hand disability that results in finger catching, clicking, or locking. Conventional treatment options such as medication, injection, and surgery have limitations. Studies have indicated that acupuncture and acupotomy can be effective in treating trigger finger. However, no review regarding these treatment modalities has been published yet. This review included randomized controlled trials published until January 2023, investigating acupuncture-related interventions. The primary outcomes of interest included the effectiveness rate (ER) and pain intensity, measured using a visual analog scale (VAS) and Numerical Rating Scale (NRS), and secondary outcomes were the Quinnell grade (QG) and recurrence rate (RR). Adverse events (AEs) have also been reported wherever available. Overall, 19 studies were included, and results demonstrated that arcedge acupuncture improved the ER and QG and reduced NRS, and acupuncture was effective in reducing VAS. Compared with conventional surgery, acupotomy alone improved the ER and QG and lowered VAS and RR, with relatively fewer AEs. Acupotomy add-on treatment was more effective than conventional treatment; however, careful interpretation is needed for VAS. Acupotomy add-on treatment was more effective than acupotomy alone. However, the overall results must be interpreted with caution because of study quality, small sample size, and heterogeneity of the results.

• Journal of Acupuncture Research
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• 제40권3호
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• pp.252-264
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• 2023

Background: The primary aim of this study is to statistically analyze and compare the difference in treatment outcomes based on the frequency and duration of acupotomy treatment for lumbar disk herniation. Methods: The evaluation of efficacy and safety involved using visual analog scale (VAS), numeric rating scale (NRS), Roland Morris disability questionnaire (RMDQ), EuroQol 5-dimention (EQ-5D), and similar parameters. This was achieved through the establishment of a comparable cohort using propensity score matching. Group A comprised 46 patients who underwent 4 sessions of acupotomy treatment for 2 weeks, while Group B consisted of 15 patients who received 6 acupotomy sessions for 3 weeks. Results: For Group A, the average amount of change in VAS values at weeks 4 and 6 was significantly decreased. However, the average amount of change in RMDQ values was not significant. Notably, the average amount of change of EQ-5D values at week 6 increased significantly. As for Group B, the average amount of change of NRS values in weeks 2 and 3 was significantly decreased. Conversely, the average amount of change in RMDQ and EQ-5D values was not significant. In comparing the 2 groups at the final follow-up, the average amount of change in all evaluation values was not significant. Further, no significant interaction effect was observed in the changes over time in all evaluation values between the 2 groups. Conclusion: This study establishes that there was no statistically significant difference in pain reduction, functional impairment, and quality of life improvement between 2 group.

• 대한약침학회지
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• 제26권3호
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• pp.227-237
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• 2023

Objectives: Pharmacopuncture is considered a unique new type of acupuncture in Korean medicine (KM). This study was performed to investigate the research trends regarding pharmacopuncture through a bibliometric analysis using VOSviewer. Methods: The Web of Science Core Collection was searched for this study. The search terms were pharmacopuncture and pharmaco-puncture. The search was conducted on May 23, 2023, and 185 studies retrieved up to this date were included. Software VOSviewer version 1.6.19 was used to perform the bibliometric analysis. After data clearing, keyword co-occurrence and cooperation pattern analyses were performed. Results: The number of studies on pharmacopuncture have gradually increased since the mid-2000s, with the most published in 2020 (46 studies). The quality of the studies has also steadily increased, and recently, several randomized controlled trials of pharmacopuncture have been conducted. Moreover, this treatment has been investigated in the context of KM clinical practice guideline development in Korea. The scope of pharmacopuncture studies to date seems to be limited to musculoskeletal pain and bee venom pharmacopuncture. The researchers from Jaseng Medical Foundation have been the core researchers in the field of pharmacopuncture in Korea. They collaborated with researchers from universities or government-funded research institutes. However, small-scale research teams from KM clinics and university researchers were also identified as independent clusters. Conclusion: Pharmacopuncture research has grown both quantitatively and qualitatively, but the scope needs to be further expanded. There is also a gap between the use of pharmacopuncture by KM doctors in clinical settings and pharmacopuncture research. Based on these findings, some suggestions for future studies in this field are discussed. Furthermore, these findings may be used as data to expand and globalize pharmacopuncture research in the future.

• 한국심리학회지 : 문화 및 사회문제
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• 제20권4호
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• pp.365-389
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• 2014

본 연구는 역경으로서의 재수를 한 대학생이 그 경험을 어떻게 인식하고 있는지를 알아보았다. Lee와 Jung(2014)의 연구에 참가한 재수경험이 있는 대학생 중에서 대학 만족 수준(더 만족/덜 만족), 재수 경험에 대한 긍정적 인식 수준(더 긍정/덜 긍정)의 4개 유형에서 각 3명씩 총 12명의 참여자를 선정하여 현상학적 질적 연구를 진행하였다. 그 결과, 재수경험에 대한 7개의 구성요소와 19개의 하위구성요소가 도출되었으며 이를 세 가지 시간적 맥락에 따라 범주화하였다. 재수경험에 대한 인식이 각 관점에 따라 달랐는데, 첫 번째는 재수과정에 대한 실천적 관점으로서, 재수는 '한계와 고통을 주지만 목표를 위해 이겨내야 하는 것'을 의미했다. 두 번째는 재수의 결과에 대한 평가적 관점으로서, 재수는 '나를 발전시키지만 보이지 않는 상처를 남기는 것'을 의미했다. 세 번째는 앞의 두 관점에서의 긍정적 또는 부정적 영향에 대해 전체적인 의미를 부여하는 의미적 관점으로서, 재수경험이 '내 삶을 있는 그대로 받아들이게 해준 것'을 의미했다. 이러한 결과를 토대로 연구의 의의와 제한점 및 추후연구에 대한 방향을 제시하였다.

• 동의신경정신과학회지
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• 제34권3호
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• pp.307-317
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• 2023

Objectives: To introduce the progress of treatment and improve clinical use after application of Emotion-to-Emotion Therapy (ETE Therapy) for treating Post-traumatic Stress Disorder (PTSD). Methods: A patient who was diagnosed with PTSD that occurred after violence in the family mainly complained about abdominal pain, depression, and fear. We treated the patient with ETE therapy as the main treatment. Subjective Units of Distress scale (SUDs), The Core Seven-Emotions Inventory Short Form (CSEI-s), and Mentalizing the Rooms of Mind (MRM) were evaluated before and after the treatment for assessing the clinical effect. Results: After treatment, overall clinical symptoms of the patient were alleviated. This result was supported by a decrease in SUDs. There were meaningful drops in 'Fear', 'Fright', 'Sorrow' in CSEI-s scores, consistent with the direction of 'Sa-seung-Gong (思勝恐)' used as major technique of ETE therapy. Resources and positive emotions in MRM were increased after treatment. Conclusions: ETE therapy may be effective for treating PTSD. It might play a significant role in cognitive reconstruction.