• Title/Summary/Keyword: PTS

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Functional Significance of Angiographic Collaterals in Patients with Totally Occluded Right Coronary Artery: Intracoronary Thallium-201 Scintigraphy (우측 관상동맥 폐쇄 환자에서 관상동맥내 Thallium-201 주사를 이용한 측부 혈행의 의의)

  • Lee, Do-Yun;Lee, Jong-Doo;Cho, Seung-Yun;Shim, Won-Heum;Ha, Jong-Won;Kim, Han-Soo;Kwon, Hyuk-Moon;Jang, Yang-Soo;Chung, Nam-Sik;Kim, Sung-Soon;Park, Chang-Yun;Kim, Young-Soo
    • The Korean Journal of Nuclear Medicine
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    • v.27 no.2
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    • pp.210-217
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    • 1993
  • To compare the myocardial viability in patients suffering from total occlusion of the right coronry artery (RCA) with the angiographic collaterals, intracoronary injection of Thallium-201 (T1-201) was done to 14 coronary artery disease (CAD) patients (pts) with total occlusion of RCA and into four normal subjects for control. All 14 CAD pts had Grade 2 or 3 collateral circulations. There were 14 male and 4 females, and their ages ranged from 31 to 70 years. In nine pts, T1-201 was injected into left main coronary artery (LCA) ($300{\sim}350{\mu}Ci$) to evaluate the myocardial viability of RCA territory through collateral circulations. The remaining five pts received T1-201 into RCA ($200{\sim}250{\mu}Ci$) because two had intraarterial bridging collaterals and three had previous successful PTCA. Planar & SPECT myocardial perfusion images were obtained 30 minutes, and four to five hours after T1-201 injection. Intravenous T1-201 reinjection (six pts) or $^{99m}Tc-MIBI$ (two pts) were also performed in eight CAD pts. Intracoronary myocardial perfusion images were compared with intravenous T1-201 (IV T1-201) images, ECG, and ventriculography. Intracoronary T1-201 images proved to be superior to that of IV T1-201 due to better myocardial to background uptake ratio and more effective in the detection of viable tissue. We also found that perfusion defects were smaller on intracoronary T1-201 images than those on the IV T1-201. All of the 14 CAD pts had either mostly viable myocardium (seven pts) or large area of T1-201 perfusion (seven pts) in RCA territory, however ventriculographic wall motion and ECG did not correlate well with intracoronary myocardial perfusion images. In conclusion, total RCA occlusion patients with well developed collateral circulation had large area of viable myocardial in the corresponding territory.

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Opposing Effects of ERK and p38 MAP Kinases on HeLa Cell Apoptosis Induced by Dipyrithione

  • Fan, Yumei;Chen, Hui;Qiao, Bo;Luo, Lan;Ma, Hsiaoyen;Li, Heng;Jiang, Jihong;Niu, Dezhong;Yin, Zhimin
    • Molecules and Cells
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    • v.23 no.1
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    • pp.30-38
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    • 2007
  • Dipyrithione (2, 2'-dithiobispyridine-1, 1'-dioxide, PTS2), a pyrithione derivate, is highly bactericidal and fungicidal. In this study we examined its apoptotic effect on HeLa cells. PTS2 induced HeLa cell death in a dose and time dependent manner. ERK1/2 and p38 were markedly activated, but little JNK1/2 activation was detected. Suppression of p38 activation by SB203580 reduced the extent of apoptosis of the HeLa cells and also prevented induction of p21, release of cytochrome c, and cleavage of caspase-3 and PARP. Inhibition of ERK1/2 with PD98059 increased apoptosis, indicating that ERK1/2 activation has an anti-apoptotic effect on PTS2-induced HeLa cell apoptosis. PTS2 also inhibited murine sarcoma 180 and hepatoma 22 tumor growth in an animal tumor model. Our findings indicate that PTS2 possesses anti-tumor activity, that caspase-3 and poly (ADP-ribose) polymerase (PARP) are involved in PTS2-induced HeLa cell apoptosis and that ERK1/2 and p38 have opposing effects on this apoptosis.

Improvement of Power Efficiency of HPA by the PAPR Reduction and Predistorter in MIMO-OFDM (MIMO-OFDM에서 PAPR 저감 및 사전 왜곡기에 의한 HPA의 전력 효율 개선)

  • Trang Ngo Thi Thu;Kim Nam;Han Tae-Young
    • The Journal of the Korea Contents Association
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    • v.5 no.1
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    • pp.201-208
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    • 2005
  • Tn this paper, we evaluate the peak-to-average power ratio (PAPR) performance in a space-time block code (STBC) multi-input multi-output orthogonal frequency division multiplexing (MIMO-OFDM) system using selected mapping (SLM) and partial transmit sequences (PTS) approaches. SLM and PTS methods are used to decrease the nonlinear distortion and to improve the power efficiency of the nonlinear high power amplifier(HPA) in the MIMO-OFDM system. In simulation result, when compared with the existing MIMO-OFDM system using QPSK, the PTS method reduces the PAPR about 5dB while the SLM method can reduce about 3.5 dB. Also, we find the BER performance of the MIMO-OFDM system with and without the predistorter in front of the HPA. When the predistorter is used, the input back-off (IBO) of 4 dB is required in the PTS method, and IBO of 6 dB in the SLM method to closely conform to the linear amplifier. If the method of improving the PAPR is not used, the value of IBO of 8 dB is required.

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PTS Technique with Low Computational Complexity for PAPR Reduction of OFDM Signals (OFDM 신호의 PAPR 감소를 위한 낮은 계산 복잡도를 갖는 PTS 기법)

  • Kong, Min-Han;Song, Moon-Kyou
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.45 no.1
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    • pp.8-13
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    • 2008
  • The high peak-to-average power ratio(PAPR) of the transmitted signals is one of the major drawbacks of the orthogonal frequency division multiplexing(OFDM). The partial transmit sequences(PTS) technique can improve the PAPR statistics of the OFDM signals. However, in the PTS technique, the computational complexity to select phase weighting factors increases exponentially with the number of sub-blocks. In this paper, a search algorithm that has no limit on the values of phase weighting factors and requires no additional operations for the search is presented. To evaluate the performance, the proposed search algorithm is compared with the full search algorithm in terms of the complementary cumulative distribution function(CCDF) of the PAPR and the computational complexity. It is shown through simulations that the proposed technique can achieve significant reductions in the computational complexity with little performance degradation compared with the full search algorithm.

Survey of Attitudes on Professionalism in Plastic and Reconstructive Surgery

  • Kim, Jin Yong;Kang, Seok Joo;Kim, Jin Woo;Kim, Young Hwan;Sun, Hook
    • Archives of Plastic Surgery
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    • v.40 no.2
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    • pp.134-140
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    • 2013
  • Background The purpose of this study is to analyze the current attitudes toward professionalism, the core values, and the type of professionalism among plastic surgeons in Korea to establish a code of ethics regarding the role of professionalism for plastic and reconstructive surgeons. Methods From March 9, to July 1, 2012, face-to-face and mail surveys were conducted targeting the 325 participants (256 specialists and 69 residents) who are registered members of the Korean Society of Plastic and Reconstructive Surgeons. The proportion of each response given to an item was obtained through statistical processing through frequency analysis. The Mann-Whitney U test was used to compare the differences in the responses between the resident group and the specialist group. Results The survey results on the perception of professionalism in plastic surgery showed that a high proportion (90.5%) of the respondents viewed the future of plastic surgeons as bright. Through evaluation of the importance of the value items,"professional dominance" (4.58 pts), "autonomy" (4.45 pts), "lifestyle" (4.34 pts), and "commercialism" (4.31 pts) were assessed as critical values. "Altruism" (3.84 pts), "interpersonal competence" (3.79 pts), and "social justice" (3.61 pts) were viewed as lesser values. This difference showed the characteristics of an entrepreneurial outlook. Conclusions Plastic surgeons should pursue excellence, humanism, accountability, and altruism in order to overcome the crisis of professionalism in plastic surgery. In order to develop the necessary competencies of professionals, vocational education should be arranged by the Korean Society of Plastic Surgeons, and an appropriate code of ethics should be established.

Measurement of nonlinear optical constant of organic single crystal para-toluene sulfonate prepared by slow solution evaporation method (늦은 용액증발법으로 제작한 유기단결정 para-toluene sulfonate의 비선형 광학상수 측정)

  • 황보창권
    • Korean Journal of Optics and Photonics
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    • v.9 no.2
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    • pp.76-85
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    • 1998
  • Organic single crystal of p-toluene sulfonate(PTS) bulks and thin films were fabricated using a slow solution evaporation method. Third and fifth order nonlinear refractive indices, $n_2$and $n_3$, of PTS crystals at 1600 nm were determined by the Z-scan method and the multimode output of the PTS thin film waveguide was observed at 1350 nm. When the beam intensity is in 2-5 GW/$cm^2$, the nonlinear refractive indices are $n_{2}=6{\times}10^{-4}cm^{2}$/GW and $n_{3}=-7{\times}10^{-5}cm^{4}/GW^{2}$ and the two and three photon absorption coefficients are zero. When the beam intensity is in 5~16 GW/$cm^2$, the split-step fast Fourier transform beam propagation method simulation shows that the beam propagation in the PTS is distorted from the gaussian shape.

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Cloning, Nucleotide Sequencing, and Characterization of the ptsG Gene Encoding Glucose-Specific Enzyme II of the Phosphotransferase System from Brevibacterium lactofermentum

  • Yoon, Ki-Hong;Lee, Kyu-Nam;Lee, Jung-Kee;Park, Se-Cheol
    • Journal of Microbiology and Biotechnology
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    • v.9 no.5
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    • pp.582-588
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    • 1999
  • A Brevibacterium lactofermentum gene coding for a glucose-specific permease of the phosphoenolpyruvate-dependent phosphotransferase system (PTS) was cloned, by complementing an Escherichia coli mutation affecting a ptsG gene with the B. lactofermentum genomic library, and completely sequenced. The gene was identified as a ptsG, which enables an E. coli transformant to transport non-metabolizable glucose analogue 2-deoxyglucose (2DG). The ptsG gene of B. lactofermentum consists of an open reading frame of 2,025 nucleotides encoding a polypeptide of 674 amino acid residues and a TAA stop codon. The 3' flanking region contains two stem-loop structures which may be involved in transcriptional termination. The deduced amino acid sequence of the B. lactofermentum enzyme $II^{GIe}$ specific to glucose ($EII^{GIe}$) has a high homology with the Corynebacterium glutamicum enzyme $II^{Man}$ specific to glucose and mannose ($EII^{Man}$), and the Brevibacterium ammoniagenes enzyme $II^{GIc}$ specific to glucose ($EII^{GIc}$). The 171-amino-acid C-terminal sequence of the $EII^{Glc}$ is also similar to the Escherichia coli enzyme $IIA^{GIc}$ specific to glucose ($IIA^{GIc}$). It is interesting that the arrangement of the structural domains, IIBCA, of the B. lactofermentum $EII^{GIc}$ protein is identical to that of EIIs specific to sucrose or $\beta$-glucoside. Several in vivo complementation studies indicated that the B. lactofermentum $EII^{Glc}$ protein could replace both $EII^{ Glc}$ and $EIIA^{Glc}$ in an E. coli ptsG mutant or crr mutant, respectively.

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Recognition of Physical Activity between Physical Therapy and Non-Physical Therapy Students: Cross-Sectional Survey

  • Ryu, Heun-Jae;Kwon, Jung-Won;Lee, Young-Min
    • The Journal of Korean Physical Therapy
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    • v.33 no.6
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    • pp.307-313
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    • 2021
  • Purpose: This study was to the investigate recognition of physical activity between physical therapy students (PTS) and non-physical therapy students (NPTS) by measuring the level of physical activity using International Physical Activity Questionnaires (IPAQ). Methods: A cross-sectional survey was completed by 191 university students. The IPAQ with an additional question (Is physical activity necessary for your future job?) was used to evaluate the recognition and the amount of physical activity. The collected data were calculated as MET-minutes scores and were classified as walking, moderate, and vigorous level of physical activity. The students were analyzed by dividing them into those who had a part-time employment (16 PTS and 12 NPTS) and those who did not have a part-time employment (80 PTS and 83 NPTS). Results: In students with a part-time employment, no significances were observed between the PTS and NPTS, in terms of MET, frequency and time of physical activity, and sitting time (p>0.05). In students without a part-time employment, the NPTS was significantly higher than the PTS for the MET and frequency of physical activity in a vigorous level (p<0.05), and there were no significant differences in other levels of physical activity (p>0.05). In the additional question, the PTS showed a slightly higher than the NPTS (p<0.05). Conclusion: The physical therapy students did not remarkable barrier to recognition of physical activity, but there was a difference in their recognition of the vigorous level of physical activity. Therefore, the understanding of physical activity for PTS would play an important role in the recognition of how physical activity can be promoted.

Effects of Short-Term Music Therapy in Fire Fighters with Post-Traumatic Stress Risk (외상 후 스트레스 위기 소방관에 대한 단기간 음악치료의 효과)

  • Shim, Gyu-Sik;Kim, Nam-Song;Bang, Sung-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.6
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    • pp.4040-4047
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    • 2015
  • The purpose of this study was to analyze a change in Post-traumatic Stress Disorder (PTSD) level and the continuity of the effects in music therapy by applying short-term music therapy program in fire fighters with Post-traumatic Stress (PTS). Forty two fire fighters in 3 districts were randomly assigned to experimental group (21 subjects) and control group (21 subjects). Music therapy was applied in totally 10 sessions by two sessions (120 minutes) a day for 5 days. PTS level was measured immediately after the end of program, after 4 weeks, and after 12 weeks. As a result, PTS level has significantly decreased into $8.90{\pm}4.55$ from $26.52{\pm}2.32$ right after the music therapy program(p<0.05). And the effect was shown to be continued significantly up to after 4 weeks($11.95{\pm}4.57$) and after 12 weeks($13.76{\pm}5.62$)(p<0.05). As a result of research, it is considered that the music therapy is effective approach for reduction in PTS as for fire fighters who belong to the group with high risk of PTSD. Accordingly, the application of regular program for managing fire fighters' mental health is understood to likely to contribute to enhancing the field service competence.

PAPR Reduction Method in Multi-Code CDMA System (다중 코드 CDMA 시스템에서 PAPR저감 기법)

  • 이강미;김상우;유흥균
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.15 no.7
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    • pp.685-691
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    • 2004
  • In this paper, we propose the hybrid methods of SLM(selected mapping) and predistortion, and PTS(partial transmit sequence) and predistortion to reduce PAPR(peak to average power ratio) and to decrease the nonlinear distortion of the nonlinear HPA(high power amplifier) in the multi-code CDMA(code division multiple access) system. The phase rotation factors are transmitted as side information in PTS and SLM methods play an important role in the BER performance. So, we present the theoretical BER equation when the errors of side information are considered in the multi-code CDMA communication system. Simulation results show that PAPR is reduced and nonlinear distortion is compensated by hybrid methods. Therefore BER performance is enhanced.