• Journal of Welding and Joining
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• v.15 no.5
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• pp.134-143
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• 1997

The formation of thick alloyed layer with high Si content have been investigated on the surface of Al alloy (A5083) plate by PTA process with Si powder. Hardening characteristics and wear resistance of alloyed layer was examined in relation to the microstructure of alloyed layer. Thick hardened layer in mm-order thickness on the surface of A5083 plate can be formed by PTA process with wide range of process condition by using Si powder as alloying element because of eutectic reaction of Al-Si binary alloy. High temperature and rapid solidification rate of molten pool, which are features of PTA process, enable the formation of high Si content alloyed layer with uniform distribution of fine primary Si paticle. High plasma arc current was beneficial to make the alloyed layer with smooth surface appearance in wide range of powder feeding rate, because enough volume of molten pool was necessary make alloyed layer. Uniform dispersion of fine primary Si particle with about 30${\mu}{\textrm}{m}$ in particle size can be obtained in layer with Si content ranging from 30 to 50 mass %. Hardness of alloyed layer increased with increasing Si content, but increasing rate of hardness differed with macrostructure of alloyed layer. Wear resistance of alloyed layer depended on $V_{si}$(volume fraction of primary Si) and was remarkably improved to two times of base metal at 20-30% $V_{si}$ without cracking, but no more improvement was obtained at larger $V_{si}$.

• Pediatric Infection and Vaccine
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• v.18 no.2
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• pp.109-116
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• 2011

Purpose : Pneumococcus is one of the most important causes of invasive infection through the childhood period. In January 2008, the Clinical and Laboratory Standards Institute (CLSI) published revised penicillin breakpoints for Streptococcus pneumoniae and penicillin susceptibility rates of S. pneumoniae increased in Korea. This study was performed to determine the probability of oral amoxicillin for the empirical treatment achieving bactericidal exposure against pneumococcus using pharmacodynamics model. Methods : Twenty-three isolates of pneumococci were subjected to determine minimum inhibitory concentration (MIC) for ${\beta}$-lactams and macrolide. For the ${\beta}$-lactams, exposure of fT >MIC (time that free drug concentrations remain above the MIC) for 50% of the administration interval have determined the probability of target attainment (PTA), and regimens that had a PTA >90% were considered optimal. An analysis was performed by applying MIC of 23 isolates to a 5000-patient Monte Carlo simulation model. Results : Among 23 isolates from healthy children, 7 (30.4%) isolates were MIC ${\leq}$1.0 ${\mu}g$/mL and 19 (82.6%) were MIC ${\leq}$2 ${\mu}g$/mL for amoxicillin. Amoxicillin 40 mg/kg/day achieved PTA >90% at MIC ${\leq}$1.0 ${\mu}g$/mL but PTA decreased to 52% at MIC 2 ${\mu}g$/mL, whereas amoxicillin 90 mg/kg/day can predict 97% of PTA at MIC 2 ${\mu}g$/mL. Overall, oral amoxicillin 90 mg/ kg/day for the empirical treatment against pneumococcus can expect more successful response in Korean children. Conclusion : Considering the resistantce pattern of pneumococci in Korean children, we estimate that oral amoxicillin 90 mg/kg/day will provide a pharmacodynamic advantage for the empirical treatment against pneumococcus. And low dose amoxicillin or macrolide are expected to have higher chance of treatment failure than high dose oral amoxicillin.

• Journal of Advanced Marine Engineering and Technology
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• v.31 no.7
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• pp.852-856
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• 2007

The Plasma Transferred Arc(PTA) overlay welding method is lately introduced as one of the most useful surface overlay method of the engine component. In this paper, the overlay welding method on the Nimonic super alloy was established by the PTA overlay welding process using the same super alloy powder. The characteristics of the Co-base and Ni-base super alloy overlay layers were investigated through the metallurgical, abrasive and cavitation erosion test. The abrasive and cavitation characteristics were investigated at room and high temperature.

• Journal of Microbiology and Biotechnology
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• v.18 no.2
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• pp.334-337
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• 2008

A tightly regulated gene expression system composed of a single-copy target gene under the control of a lac promoter derivative and lacI gene in a multicopy plasmid is proposed, and its ability to control the flux of a metabolic pathway is demonstrated. A model system to control the flux of acetyl-CoA to acetyl phosphate was constructed by integrating pta, a gene encoding phosphotransacetylase, under a tac promoter into the chromosome of E. coli with a pta-negative background and transforming a multicopy plasmid containing the $lacI^Q$ gene into the strain. The production rate of acetate was shown to be tightly controlled when varying the concentration of the inducer (IPTG) in he model system.

• Environmental Engineering Research
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• v.19 no.4
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• pp.355-361
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• 2014

The wastewater treatment with a two-phase expanded granular sludge bed (EGSB) system for anaerobic degradation of acetate, benzoate, terephtalate and p-toluate from purified terephtalic acid (PTA) production was studied. The feasibility and effectiveness of the system was evaluated in terms of organic oxidation by chemical oxygen demand (COD), gas production, bacterial adaptability and stability in the granular sludge. Average removal efficiencies 93.5% and 72.7% were achieved in the EGSB reactors under volumetric loading rates of $1.0-15kg-COD/m^3/day$ and terephtalate and p-toluate of 351-526 mg/L, respectively. Gas production reached total methane production rate of 0.30 L/g-COD under these conditions in the sequential EGSB reactor system. Higher strength influent COD concentration above 4.8 g-COD/L related to field conditions was fed to observe the disturbance of the EGSB reactors.

• Proceedings of the KSME Conference
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• 2002.08a
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• pp.263-266
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• 2002

The KSR-III developed by KARI is the first rocket vehicle which is adopting the liquid propellant rocket engine system in Korea. Not only the engine itself, but also the propellant feeding system is one of the most important component in liquid rocket vehicle. In this paper, the authors are intended to introduce the multi-purpose test facility(PTA-II Test Facility) which is constructed for the variety of tests on KSR-III feeding system(single component tests, verification tests, cold flow tests and combustion tests). With the results of these tests, we can identify the characteristics of rocket feeding system and decide the optimum setting values of feeding system for the successful flight.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2003.05a
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• pp.193-196
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• 2003

The KSR-III developed by KARI is the first rocket vehicle which is adopting the liquid propellant rocket engine system in Korea and its flight test was successfully done last year. KSR-III is a sounding rocket class launch vehicle, but there is a sense to accomplish design, manufacture, performance test and finally its flight test by domestic technology. In this paper, the authors are intended to introduce the multi-purpose test facility(PTA-II Test Facility) which is constructed for the variety of tests on KSR-III feeding system(single component tests, verification tests, cold flow tests and combustion tests) and its test results.

• Proceedings of the KAIS Fall Conference
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• 2004.06a
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• pp.92-95
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• 2004

플라즈마 트랜스퍼드 아크(PTA) 용사는 플라즈마 아크 용접 장치에 선형의 용접봉을 이용하는 대신 분말 형태의 용접재를 주입하여 주로 마모나 부식에 노출되는 금속의 표면에 적용하여 금속 표면의 내식 내마모 특성을 향상시키는 기술이다. 본 논문에서는 용사전류가 표면개질부에 미치는 기하학적 형상 및 미세조직에 미치는 영향에 대하여 알아보았다. 낮은 전류에서는 접합이 이루어지지 않았고 높은 전류에서는 모재로 희석되어 들어가는 현상을 보였다.

• Korean Journal of Radiology
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• v.23 no.10
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• pp.949-958
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• 2022

Objective: To investigate the feasibility of using a deep learning-based analysis of auscultation data to predict significant stenosis of arteriovenous fistulas (AVF) in patients undergoing hemodialysis requiring percutaneous transluminal angioplasty (PTA). Materials and Methods: Forty patients (24 male and 16 female; median age, 62.5 years) with dysfunctional native AVF were prospectively recruited. Digital sounds from the AVF shunt were recorded using a wireless electronic stethoscope before (pre-PTA) and after PTA (post-PTA), and the audio files were subsequently converted to mel spectrograms, which were used to construct various deep convolutional neural network (DCNN) models (DenseNet201, EfficientNetB5, and ResNet50). The performance of these models for diagnosing ≥ 50% AVF stenosis was assessed and compared. The ground truth for the presence of ≥ 50% AVF stenosis was obtained using digital subtraction angiography. Gradient-weighted class activation mapping (Grad-CAM) was used to produce visual explanations for DCNN model decisions. Results: Eighty audio files were obtained from the 40 recruited patients and pooled for the study. Mel spectrograms of "pre-PTA" shunt sounds showed patterns corresponding to abnormal high-pitched bruits with systolic accentuation observed in patients with stenotic AVF. The ResNet50 and EfficientNetB5 models yielded an area under the receiver operating characteristic curve of 0.99 and 0.98, respectively, at optimized epochs for predicting ≥ 50% AVF stenosis. However, Grad-CAM heatmaps revealed that only ResNet50 highlighted areas relevant to AVF stenosis in the mel spectrogram. Conclusion: Mel spectrogram-based DCNN models, particularly ResNet50, successfully predicted the presence of significant AVF stenosis requiring PTA in this feasibility study and may potentially be used in AVF surveillance.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2009.10a
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• pp.358-361
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• 2009

The increasing interest in the surface modification technology by the plasma transferred arc overlaying process in the material processing is placing stringent demands on the manufacturing techniques and performance requirements, and the manufacture employs the high quality and efficiency plasma transferred arc overlaying technology. This paper covers recent technical trends of plasma transferred arc overlaying technology including the COMPENDEX DB analysis.