• Korean Journal of Acupuncture
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• 제29권1호
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• pp.109-116
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• 2012

저자는 견비통, 요통, 완관절통을 각각 호소하는 환자들을 대상으로 다른 병행치료 없이 피내침만을 시행한 결과 SF-MPQ, VAS, PRS상 모두 통증 지수가 감소하는 일정 효과를 볼 수 있었다. 이상의 결과로 미루어 다양한 통증 환자에게 피내침을 시행한다면 양호한 임상 경과를 가져올 것으로 사료되며, 향후 더 많은 연구가 필요할 것으로 생각된다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2010년도 제39회 하계학술대회 초록집
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• pp.65-65
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• 2010

Extreme ultraviolet lithography (EUVL) is expected to be applied for making patterns below 32 nm in device industry. An ultrathin EUV photoresist (PR) of a few nm in thickness is required to reduce minimum feature size further. Here, we show that pentacene molecular layers can be employed as a new EUV resist for the first time. Dots and lines in nm scale are successfully realized using the new molecular resist. We clearly provide the mechanism for forming the nanopatterns with scanning photoemission microscope (SPEM), EUV interference lithography (EUV-IL), atomic force microscope (AFM), photoemission spectroscopy (PES), etc. The molecular PR has several advantages over traditional polymer EUV PRs; for example, high thermal/chemical stability, negligible outgassing, ability to control the height and width on the nanometer scale, leaving fewer residuals, no need for a chemical development process and thus reduction of chemical waste to make the nanopatterns. Besides, it could be applied to any substrate to which pentacene bonds chemically, such as $SiO_2$, SiN, and SiON, which is of importance in the device industry.

• Biomolecules & Therapeutics
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• 제29권4호
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• pp.373-383
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• 2021

Atherosclerosis is the deposition of plaque in the main arteries. It is an inflammatory condition involving the accumulation of macrophages and various lipids (low-density lipoprotein [LDL] cholesterol, ceramide, S1P). Moreover, endothelial cells, macrophages, leukocytes, and smooth muscle cells are the major players in the atherogenic process. Sphingolipids are now emerging as important regulators in various pathophysiological processes, including the atherogenic process. Various sphingolipids exist, such as the ceramides, ceramide-1-phosphate, sphingosine, sphinganine, sphingosine-1-phosphate (S1P), sphingomyelin, and hundreds of glycosphingolipids. Among these, ceramides, glycosphingolipids, and S1P play important roles in the atherogenic processes. The atherosclerotic plaque consists of higher amounts of ceramide, glycosphingolipids, and sphingomyelin. The inhibition of the de novo ceramide biosynthesis reduces the development of atherosclerosis. S1P regulates atherogenesis via binding to the S1P receptor (S1PR). Among the five S1PRs (S1PR1-5), S1PR1 and S1PR3 mainly exert anti-atherosclerotic properties. This review mainly focuses on the effects of ceramide and S1P via the S1PR in the development of atherosclerosis. Moreover, it discusses the recent findings and potential therapeutic implications in atherosclerosis.

• 한국항해항만학회지
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• 제46권5호
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• pp.435-440
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• 2022

The development and introduction of a Maritime Autonomous Surface Ship (MASS) are some of the most important changes leading to the fourth industrial era in the maritime area. The term 'MASS' refers to a ship operating independently, without human intervention, to reduce maritime accidents caused by human errors. Recent UK findings MASS also noted that particularly the dynamic positioning system will be considered to apply as newly function to a MASS. The DP system, a ship system developed decades ago and used for specific purposes like offshore operations, provides various functions to facilitate the accurate movements of the vessel, and operators can make decisions within the DP system, in addition to the ordinary ship system. In this paper, it would like to present the connection and application method with the main technical elements of the DP system in connection with the main technology of the DP system to achieve the safe operation of a MASS. In particular, among various position reference systems, the capability plot function of DP system, and the "follow target" mode in the operation mode are attractive functions that can contribute to the safe operation of autonomous ships.

• Geomechanics and Engineering
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• 제30권1호
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• pp.75-91
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• 2022

This paper aims to show how to use several Machine Learning (ML) methods to estimate the TBM penetration rate systematically (TBM-PR). To this end, 1125 datasets including uniaxial compressive strength (UCS), Brazilian tensile strength (BTS), punch slope index (PSI), distance between the planes of weakness (DPW), orientation of discontinuities (alpha angle-α), rock fracture class (RFC), and actual/measured TBM-PRs were established. To evaluate the ML methods' ability to perform, the 5-fold cross-validation was taken into consideration. Eventually, comparing the ML outcomes and the TBM monitoring data indicated that the ML methods have a very good potential ability in the prediction of TBM-PR. However, the long short-term memory model with a correlation coefficient of 0.9932 and a route mean square error of 2.68E-6 outperformed the remaining six ML algorithms. The backward selection method showed that PSI and RFC were more and less significant parameters on the TBM-PR compared to the others.

• 아태비즈니스연구
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• 제13권3호
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• pp.119-134
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• 2022

Purpose - The purpose of this study was to expound the packaging framework system(PFS) under international trade rules. Design/methodology/approach - This study analyzed packaging framework system and packaging regulations and technical standards in international regulations and major countries and classified these in some standards Findings - First, the study provides packaging provisions associated with packaging regulations and technical standards (PRTS). Then, the basis of PFS in international trade rules was proposed; it is believed that the PFS was composed of packaging legal system in WTO institutional framework (WTO-PLS), international organization packaging standard system (IO-PSS) and major countries or regions packaging regulatory system (MCR-PRS). Secondly, this paper expounded relations and legal characteristics of the three packaging systems. Finally, This study investigated PRTS coverage under technical barriers to trade (TBT) and Sanitary and Phytosanitary measures (SPS). Research implications or Originality - The regulations associated with PRTS have played a key role in challenges to merchandise trade in international trade. This study has significance in classifying packaging related reticulations into several criteria unlike previous studies. Therefore it is hope that this study can provide a supplementary document for the existing research of PRTS.

• 환경영향평가
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• 제23권2호
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• pp.101-111
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• 2014

The research was carried out in order to find climate factors which determine the distribution of Neolitsea sericea, and the potential habitats (PHs) under the current climate and three climate change scenario by using species distribution models (SDMs). Four climate factors; the minimum temperature of the coldest month (TMC), the warmth index (WI), summer precipitation (PRS), and winter precipition (PRW) : were used as independent variables for the model. Three general circulation models under A1B emission scenarios were used as future climate scenarios for the 2050s (2040~2069) and 2080s (2070~2099). Highly accurate SDMs were obtained for N. sericea. The model of distribution for N. sericea constructed by SDMs showed that minimum temperature of the coldest month (TMC) is a major climate factor in determining the distribution of N. sericea. The area above the $-4.4^{\circ}C$ of TMC revealed high occurrence probability of the N. sericea. Future PHs for N. sericea were projected to increase respectively by 4 times, 6.4 times of current PHs under 2050s and 2080s. It is expected that the potential of N. sericea habitats is expanded gradually. N. sericea is applicable as indicator species for monitoring in the Korean Peninsula. N. sericea is necessary to be monitored of potential habitats.

• Journal of Preventive Medicine and Public Health
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• 제46권2호
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• pp.89-95
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• 2013

Objectives: Little is yet known about the determinants of bone mineral density (BMD) in young adults. Thus, in this study, we aimed to determine the factors that have an impact on BMD in young men. Methods: Questionnaires were sent out to 111 male medical students. Information on age, socio-economic status, medical history, lifestyle, physical activity during adolescence, school club participation, current physical activity, and dietary intake were collected by the survey. Height, weight, percent body fat and muscle mass were estimated by bioelectrical impedance, and BMD was obtained using calcaneal quantitative ultrasound. Using the Poisson regression model, prevalence ratios (PRs) were used to estimate the degree of association between risk factors and osteopenia. Results: The height and current physical activity showed a correlation to the Osteoporosis Index. Among the categorized variables, past physical activity during adolescence (p= 0.002) showed a positive effect on the bone mineral content. In the multivariate model, past physical activity (${\geq}1$ time/wk) had a protective effect on osteopenia (PR, 0.37; 95% confidence interval [CI], 0.18 to 0.75) and present physical activity (1000 metabolic equivalent of task-min/wk) decreased the risk of osteopenia (PR, 0.64; 95% CI, 0.44 to 0.91). Conclusions: Past physical activity during adolescence is as important as physical activity in the present for BMD in young men.

• 정보처리학회논문지A
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• 제13A권1호
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• pp.11-18
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• 2006

다양한 네트워크로 구성된 인터넷 환경에서 오버레이 홉 수를 최소화하는 Chord를 비롯한 기존의 분산 해싱 테이블 기반의 피어-투-피어 시스템에서는 목적 노드까지의 실질적인 질의 라우팅 시간을 줄일 수 없다. 따라서 제안하는 적응적 근접경로 선택기법에서 각 노드는 라우팅테이블의 엔트리 노드 중 지연시간을 최소로 하는 노드를 선택하여 질의 메시지를 전달하도록 한다. 이를 위하여 각 엔트리의 목적지까지의 지연시간을 큐 라우팅 알고리듬과 지수적 최근-가중치 평균을 이용해 예측하여 검색 테이블로 저장하고, 노드들 간 메시지 전달 시 이 정보를 교환하여 추가 부하 없이 검색 테이블에 반영한다. 시뮬레이션을 통해 제안하는 기법이 전채 검색 시간과 흡 간 지연시간에 있어서 근접성을 고려하지 않은 Chord나 CFS의 서버 선택 알고리즘에 비해 월등히 좋은 성능을 보임을 확인할 수 있다.

• Journal of Preventive Medicine and Public Health
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• 제50권4호
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• pp.228-239
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• 2017

Objectives: This study aimed to examine the association between preschool education experiences and adulthood self-rated health using representative data from a national population-based survey. Methods: Data from the Korean Labor and Income Panel Study in 2006 and 2012 were used. A total of 2391 men and women 21-41 years of age were analyzed. Log-binomial regression analyses were conducted to examine the associations between preschool education experience and self-rated health in adulthood. Parental socioeconomic position (SEP) indicators were considered as confounders of the association between preschool education experience and adulthood subjective health, while current SEP indicators were analyzed as mediators. Age-adjusted prevalence ratios (PRs) and the associated 95% confidence intervals (CIs) were estimated. Results: Compared with men without any experience of preschool education, those with both kindergarten and other preschool education experiences showed a lower prevalence of self-rated poor health (PR, 0.65; 95% CI, 0.47 to 0.89). In women, however, such an association was not evident. The relationship of preschool education experiences with self-rated poor health in adulthood among men was confounded by parental SEP indicators and was also mediated by current SEP indicators. After adjustment for parental and current SEP indicators, the magnitude of the associations between preschool education experiences and adulthood subjective health was attenuated in men. Conclusions: Preschool education experience was associated with adulthood self-rated health in men. However, this association was explained by parental and current SEP indicators. Further investigations employing a larger sample size and objective health outcomes are warranted in the future.