• Journal of Nutrition and Health
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• v.57 no.2
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• pp.211-227
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• 2024

Introduction: Seaweed is a sustainable and underexplored source of bioactive compounds with potent anti-inflammatory activities. However, studies on the interaction between seaweed and genes on inflammation are limited. Purpose: We aimed to evaluate the relationships between seaweed consumption and the polygenic risk scores (PRS) and their interactions with high-sensitivity C-reactive protein (hs-CRP) levels. Methods: Information on seaweed consumption was collected using a food frequency questionnaire, which included laver, kelp, and sea mustard among the items consumed. A total of 31 hs-CRP-related single nucleotide polymorphisms (SNPs) were selected using genome-wide association studies and clumping analysis, and the individual PRS were calculated by weighting the effect size of each allele in the selected SNPs of 39,369 middle-aged (≥40 years) Koreans using the Korean Genome and Epidemiology Study (KoGES)-Health Examinees (HEXA) cohort data. To investigate the interaction between seaweed intake and the PRS on hs-CRP levels >1 mg/L, hazard ratios (HRs) and 95% confidence intervals (CIs) were assessed using multivariable Cox proportional hazards models. Results: During a mean follow-up period of 4.8 years, we recorded 436 patients with elevated hs-CRP levels. Women in the highest tertile of the PRS with the lowest quartile of seaweed intake had an increased incidence of elevated hs-CRP levels compared with women in the lowest tertile of the PRS with the lowest seaweed intake quartile (HR 2.34, 95% CI 1.23-4.45). No significant association was observed among the men. Conclusion: In conclusion, we identified a new interaction between the PRS, seaweed intake, and inflammation in Korean women, and this study suggests that the interaction between the identification of genetic predisposition and dietary seaweed intake may have an impact on determining the risk of developing hyperinflammation in the future.

• Proceedings of the IEEK Conference
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• 1999.06a
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• pp.57-60
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• 1999

In many radio communication environments, there is a special component, called inter-symbol interference (ISI), mused by multipath time delay of signal and ISI components impose limitation of the data transmission rate. In this paper, we consider signaling pulse shapes, called partial response signaling (PRS), for minimizing the effect of ISI and show the improvement of performance by applying one of the partial-response signaling (PRS) pulses to two types of receiver system under dependent noise environments through the Monte-Carlo computer simulations.

• Ocean and Polar Research
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• v.28 no.2
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• pp.107-117
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• 2006

Freshwater algal studies in North polar environments are relatively few. This study presented the algal-flora, -biomass and genetic features of dominant cells collected from temporary ponds around the Polar Research Station (PRS), Norway. Water samples were collected from 4 stations around PRS, and analyzed for their environmental and biological variables. Water temperature, salinity and conductivity ranged from 5 to $10^{\circ}C$, 0.1 to $0.3%_{\circ}$ and 0.21 to $0.36{\mu}S/cm$, respectively. Chlorophyll a concentration ranged from 1.8 to $11.1{\mu}g/l$, and that of the size-fractionated cells was recorded from 0.7 to $1.1{\mu}g/l$ in picoplankton 0.3 to $6.5{\mu}g/l$ in nanoplankton, and 0.4 to $3.9{\mu}g/l$ in microplankton respectively. Algal flora in the present study was recorded as 10 genera, in which Chlamydomonas, particularly, was dominant in all studied sites. By comparison of Chlamydomonas 18S rDNA sequences, including two isolates from PRS, they formed a distinct clade against others: sequence similarity was significantly low (<97.2%) with C. noctigama, being the highest score by BLAST search in GenBank. This study was valuable for basic knowledge regarding the freshwater algae around PRS and their genetic information.

• The Korean Journal of Pain
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• v.14 no.2
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• pp.214-217
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• 2001

Background: Intra-articular injection is a commonly performed procedure in patients with degenerative osteoarthritis of the knee. Several drugs are used for relief of pain in such cases. Local anesthetics, clonidine and steroids have been confirmed to be effective when used in an intra-articular injection. Ketorolac has recently become one of the most commonly used and potent NSAIDs. There have been many studies about the effect of ketorolac. Methods: Sixty-four patients were divided into 2 groups. In Group I (n = 31), 0.5% bupivacaine 3 ml and sodium hyaluronate 20 mg were used and in Group II (n = 33), 0.5% bupivacaine 3 ml, sodium hyaluronate 20 mg and ketorolac 5 mg were used. We observed the pain relief scale (PRS) at 15 minutes, 1 week and 1-3 months after injection. Results: After 15 minutes, PRS scores were $6.6{\pm}2.7$ (Group I) and $5.1{\pm}3.1$ (Group II), so there was a statistical difference between the two groups. After 1 week, the PRS scores were $5.9{\pm}2.0$ (Group I) and $5.8{\pm}2.4$ (Group II). At 1-3 months later, PRS scores were $5.6{\pm}3.0$ (Group I) and $5.1{\pm}2.7$ (Group II). Thus, there were no significant statistical differences between the two groups at 1 week or 1-3 months later, although some patients were more satisfied with pain relief in Group II at 1-3 months. Conclusions: Ketorolac provides more rapid pain relief of degenerative arthritis when used in intra-articular injection. And there was no statistical difference of effect after 1 week or 1-3 months later. Further studies are required on the effect of the intra-articular use of ketorolac.

• Journal of Acupuncture Research
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• v.21 no.5
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• pp.113-122
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• 2004

Objective : This study is designed in order to evaluate the therapeutic effect of venesection on acute low back pain. Methods : From Nov. 1st 2003 to Apr. 30th 2004, 40 cases of low back pain patients at acute stage were divided into 2 groups; one group(control group) took only acupuncture therapy, and the other group(test group) took acupuncture and venesection therapy. Pain rating score(PRS) was used to assess the pain for its intensity, frequency, duration, and aggravating factors. And visual analog scale(VAS) was used, too. PRS and VAS was checked twice, before the treatment and after the treatment. Treatment was done twice a day. Results : Both acupuncture therapy and acupuncture with venesection therapy showed good effect on low back pain of acute stage. And the latter group showed better effect on decreasing pain than former. It was proved by the difference between PRS and VAS checked before treatment and what checked after treatment. But it was not proved statistically. Conclusion : Only acupuncture and acupuncture with venesection can be recommended as a useful therapy to treat low back pain of acute stage.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.2 no.1
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• pp.27-35
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• 1998

In this paper, we propose a novel spectral-chopping model of Class-II$(1+D)^2$ -PRS system which reveals improved spectral efficiency. We build up the model having spectrum chopped by the amount of Nyquist over-rate, and then compare its characteristics with the conventional model in both the time-domain and the frequency-domain. When the transmission system operates above the Nyquist rate, the new model has better performance than the conventional PRS using its inherent speed-tolerance. According to our investigations, Class-II PRS shows more excellent effect in the spectral-chopping method than Class- I and W types analyzed previously. We ascertain that the over-rate of 26.675 obtained by the inherent speed-tolerance could be improved upto 40% using spectrum-truncation. These effects come from the fact that the raised-cosine spectrum of Class-II PRS has smaller Boss of frequency component and energy than any other types for the same amount of truncation. In order to validate these theoretical results, we present their sidelobe-trends confirming cancellation effects at the sampling instants and some experimental results showing their patterns of eye-openings and spectra.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.26 no.2
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• pp.45-53
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• 2020

Purpose: The purpose of this study was conducted to investigate the effects of kinesio taping and coordination exercise on the myofascial pain syndrome and shoulder function. Methods: The patients with myofascial pain syndrome were participated in this study and divided randomly 2 groups. Control group (n=22) was taken only physical therapy program. Experimental group (n=22) was taken physical therapy with Kinesio taping and coordination exercise. The Kinesio taping in experimental group applied on levator scapulae and supraspinatus. The coordination exercise performed in supine position and sitting position on 15 times during 10 seconds each positions. We measured the pain degree using visual analog scale (VAS), pain rating score (PRS), pressure pain threshold (PPT), myofascial pain subjects symptoms index and shoulder motor function using constant shoulder assessment scale; CSA before and after experiment. Results: The significant test of CSA, myofascial pain subjects symptoms index, VAS, PRS according to applying the Kinesio taping and coordination exercise between groups used ANCOVA. In the result following analysis, there was significance on VAS (F=13.071, p=.031), PRS (F=12.130, p=.014), PPT (F=7.378, p=.016), CSA (F=5.302, p=.026) between control group and experimental group. Conclusion: Then, Kinesio taping and coordination exercise has benefit on the VAS, PRS, PPT, CSA in patients with myofascial pain syndrome. So, it may suggest that Kinesio taping combined with coordination exercise will be helpful of the pain and shoulder function improvement the patients with myofascial pain syndrome.

• Herbal Formula Science
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• v.20 no.1
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• pp.149-158
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• 2012

Objectives : The purpose of this study is to evaluate the effect of oriental medical combined treatment on the fibromyalgia syndrome patient. Methods : Oriental medical combined treatment was administered during 3 weeks at 2 times admissions. The improvement of clinical symptom was evaluated by VAS(visual analogue scale), SF-MPQ(short form-McGill pain questionnarie) and PRS(pain rating scale), change of tender points. Results : After treatment, the patient's VAS score was reduced to 3-5, 4-5 point. First admission, there is no observable change in the SF-MPQ. But, Second admission, SF-MPQ score was reduced from 16 to 6. The PRS score was reduced from 72 to 24, from 75 to 48 respectively. Tender points was reduced generally. Conclusions : Oriental medical combined treatment for the fibromyalgia syndrome patient was effective. Although this case presented valuable result, further research is encouraged to confirm the effectiveness of this treatment with large number of patient.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.19 no.4
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• pp.597-604
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• 1994

In this paper, the "Stop-and-GO" algorithm is applied to the PRS(Partial Response Signal) type signaling. Stop-and-GO blind equalizer has a property of stopping the adaptation of its tab coefficients by means of a simples flag telling the equalizer whether the current output error with respect to decided symbol is sufficiently reliable to be used. PRS has the rule os level transition, which makes it possible that the level of currently received symbol is in the adjacent levels of the previously received symbol. New nonlinear estimators for PRS, based on the rule of level transition, is proposed. The computer simulation results show the improvement in performance achievable with proposed nonlinear estimators.stimators.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.43 no.1 s.307
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• pp.9-16
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• 2006

RDA(Relational Discriminant Analysis) is a way of finding classifiers based on the dissimilarity measures among the prototypes extracted from feature vectors instead of the feature vectors themselves. Therefore, the accuracy of the RDA classifier is dependent on the methods of selecting prototypes and measuring proximities. In this paper we propose to utilize PRS(Prototype Reduction Schemes) and Mahalanobis distances to devise a method of increasing classification accuracies. Our experimental results demonstrate that the proposed mechanism increases the classification accuracy compared with the conventional approaches for samples involving real-life data sets as well as artificial data sets.