• Parasites, Hosts and Diseases
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• 제39권1호
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• pp.57-66
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• 2001

In the course of immunoscreening of Clonorchis sinensis cDNA library, a cDNA CsRP12 containing a tandem repeat was isolated. The cDNA CsRP 12 encodes two putative peptides of open reading frames (ORFs) 1 and 2 (CsRP12-1 and -2). The repetitive region is composed of 15 repeats of 10 amino acids. Of the two putative peptides, CsRP12-1 was proline-rich and found to have homologues in several organisms. Recombinant proteins of the putative peptides were bacterially produced and purified by an affinity chromatography Recombinant CsRP12-1 protein was recognized by sera of clonorchiasis patients and experimental rabbits, but recombinant CsRP 12-2 was not. One of the putative peptide, CsRP12-1, is designated CsPRA, proline-rich antigen of C. sinensis. Both the C-termini of CsRP12-1 and -2 were bacterially produced and analysed to show no antigenicity. Recombinant CsPRA protein showed high sensitivity and specificity. In experimental rabbits, IgG antibodies to CsPRA was produced between 4 and 8 weeks after the infection and decreased thereafter over one you. These results indicate that CsPRA is equivalent to a natural protein and a useful antigenic protein for serodiagnosis of human clonorchiasis.

• 한국운동역학회지
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• 제30권2호
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• pp.155-163
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• 2020

Objective: This study to identify the mechanism of head impact that occurs during youth soccer game with regard to head injuries in sports. Method: Ten male subjects (age: 10.0±2.0 yrs.) were participated during 10 soccer practices spread out over a time period of 10 weeks. During each soccer game, the participants agreed and wore the X-Patch (wireless accelerometer, gyroscopes). The X-Patch records the head impact mechanics, such as peak linear acceleration (PLA), peak rotational acceleration (PRA), peak rotational velocity (PRV), Head Injury Criterion (HIC), and the location of impact. Results: A total of 501 impacts to the head were measured over the 10 soccer games, PLA 17.8±10.4 g, PRA 3168±2442 rad/s²; PRV 16.1±10.6 rad/s; HIC 11.7±34.2. The severity of impact was classified into 3 ranges; low 10~39 g (482 impacts); medium 40~69 g (17 impacts); and high >69 g (2 impacts). There are no significant differences in PLA and HIC (p=0.08, p=0.15), however PRA and PRV show the differences (p<.05) between each of the participants. For the analysis comparing between the soccer games, there are no significant differences in PLA, PRA, PRV and HIC (p=0.11, p=0.13, p=0.14, p=0.05). Conclusion: Our results indicated that there were significant differences between athletes, especially in terms of rotational acceleration, whereas there were significant differences in linear and rotational based variable between each of the soccer games. Although the vast majority of impacts were below 39 g there were 2 potentially dangerous impacts above 69 g. It is important that future research continuous to measure head impact mechanics during soccer to help understand head injury mechanisms to ensure the safety of athletes.

• 한국컴퓨터정보학회논문지
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• 제17권1호
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• pp.141-149
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• 2012

본 연구에서는 이종 무선융합망에서 실시간 서비스 품질의 지속성을 보장하면서도 자원의 이용도를 극대화하기 위한 자원운영 방안인 PRA(Priority Resource Allocation)를 제안한다. PRA에서는 예약된 자원을 사용하여 실시간 서비스 데이터를 우선적으로 전송하되 그 전송률이 감소하면 비실시간 서비스가 여분의 대역폭을 일시적으로 이용한다. 실시간 세션의 가변 전송률에 근거한 통계적 다중화 기법을 통하여 PRA 방식이 실시간 서비스의 품질을 만족시키면서도 동시에 접속 가능한 가입자 수를 최대화할 수 있음을 시뮬레이션에 의해 확인한다.

• Nuclear Engineering and Technology
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• 제45권6호
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• pp.767-790
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• 2013

MAAP4 is a computer code that can simulate the response of a light water reactor power plant during severe accident sequences, including actions taken as part of accident management. The code quantitatively predicts the evolution of a severe accident starting from full power conditions given a set of system faults and initiating events through events such as core melt, reactor vessel failure, and containment failure. Furthermore, models are included in the code to represent the actions that could mitigate the accident by in-vessel cooling, external cooling of the reactor pressure vessel, or cooling the debris in containment. A key element tied to using a code like MAAP4 is an uncertainty analysis. The purpose of this paper is to present a MAAP4 based analysis to examine the sensitivity of a key parameter, in this case hydrogen production, to a set of model parameters that are related to a Level 2 PRA analysis. The Level 2 analysis examines those sequences that result in core melting and subsequent reactor pressure vessel failure and its impact on the containment. This paper identifies individual contributors and MAAP4 model parameters that statistically influence hydrogen production. Hydrogen generation was chosen because of its direct relationship to oxidation. With greater oxidation, more heat is added to the core region and relocation (core slump) should occur faster. This, in theory, would lead to shorter failure times and subsequent "hotter" debris pool on the containment floor.

• Journal of Microbiology and Biotechnology
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• 제14권4호
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• pp.868-871
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• 2004

Candida albicans has become the most important human pathogen in immunocompromised patients. One important feature of the pathogenicity in C. albicans is the morphological transition from yeast to hyphae. Previously, we reported that lysophosphatidylcholine (Lyso-PC) suppressed the hyphal transition through the MAP kinase pathway (Min et al., 2001). Therefore, it should be useful to examine the unknown genes involved in the MAP kinase pathway. As a way to identify target genes of Lyso-PC in hyphal suppression, this present study exploited two-dimensional electrophoresis. It was revealed that Lyso-PC suppressed expression of Phr1p and Pra1p, surface proteins involved in the morphogenesis.

• 기록학연구
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• 제6호
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• pp.3-40
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• 2002

Appraisal is a basic archival function that analyzes values of records and determines the eventual disposal of records based upon their archival values. In Korea, this appraisal concept introduces in earnest through Public Records and Archives Act(PRA, 공공기관의 기록물관리에관한법률) with which Korean record management systems settle inflexibly. In theoreical and methodological area, therefore, it is necessary to analyze appraisal system in this Act with it in archival science. In PRA Act, appraisal system is founded on the Tables of Transaction for Records Scheduling(TRS, 기록물분류기준표) through which disposal activities of all records are definited in a concrete form. In this system, selection of archival materials which has been recognized as a important function of record center is carried out by record creators and archival institutions; Primary value between semi-currenty and non-currenty are reflected at the same time. In view of values, this appraisal system intends to separate reasonably consideration for continuing utility of achives from current use of records throughout agencies duration. Ultimately, appraisal based upon TRS makes up not separated management course but organic courses reflecting the Continuum of Care. Of course, this appraisal system makes up the deficiency partially. TRS regarded as 'mainboard' of current appraisal system will have to be enacted elaborately. And appraisal strategies of electronic records must set up in detail in PRA Act and TRS. Lastly, arrangement and description concepts immanent in TRS will have to supplement in archival institutions.

• 한국안광학회지
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• 제12권3호
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• pp.125-130
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• 2007

이 논문은 중고등학생 41명(12-17세)의 근업시 자각 증상과 양안시 기능의 관계를 알아보고자 한 연구이다. CISS 설문 평가, 조절력검사, 조절 용이성검사, Negative relative accommodation(NRA)/Positive relative accommodation (PRA), 폭주 근점(NPC)검사, 사위검사, 그리고 AC/A(A, accommodation; C, convergence) 비를 측정하였다. 이들 검사의 결과는 정상 기댓값과 비교하여 정상 군과 이상 군으로 분류하였다. 폭주 부족보다는 조절 부족이 더 많았고 외사위보다는 내사위가 많았다. NRA/PRA는 높게 나타났고 AC/A 비는 낮게 나타났다. CISS 검사 결과는 다음과 같다; 근업시 가장 흔한 증상은 피로감이었고, 전체 증상의 점수에 대한 평균은 $16.63{\pm}7.49$이었고, 평균적인 증상의 수는 $10.07{\pm}3.04$이었고 중증 증상 수의 평균은 $1.98{\pm}2.13$이었다. 증상의 점수, 증상의 수, 증상의 심한 정도에 따라 4개의 그룹으로 분류한 후 양안시 검사의 결과와 비교하여 상관성을 분석하였다. 그룹과의 상관성은 NRA가 가장 높게 나타났고 증상의 점수는 조절 용이성, 증상의 수는 NRA, 그리고 중증 증상의 수는 근거리 사위 량이 가장 높게 나타났다. NRA는 근업 증상과 관련하여 모든 부분에서 가장 상관성이 높은 것을 보여주었다.

• 대한임상검사과학회지
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• 제45권2호
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• pp.48-53
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• 2013

Recently, the isolation rate of nontuberculous mycobacteria (NTM) in clinical laboratories and the incidence of NTM infections are on the increase in Korea, but there have been only a few studies that reveal the general aspect of NTM isolation or species distribution. Therefore, this study was performed to examine the species identification by PCR-restriction fragment length polymorphism analysis (PRA, PCR-RFLP), and the clinical significance of mycobacterial cultures. PRA was used during the novel region of the rpoB gene and was developed for rapid and precise identification of mycobacteria to the species level. From January 2012 to April 2012, we examined pre-identified nontuberculous mycobacteria (60 species in 3 hospital of Busan-Kyeongnam area). We confirmed 4 (6.6%) Mycobacterium tuberculosis (MTB) and 56 (93.4%) NTM from 60 pre-identified NTM species by multiplex PCR (MolecuTech $MTB-ID^R$ V3, YD Diagnostics, Korea) and PRA (Myco-ID, YD Diagnostics, Korea). The distribution of 56 NTM species were M. intracellulare type I 15 (26.7%), M. avium 14 (25%), M. abscessus 11 (19.5%), M. kansasii type I 3 (5.4%), M. pulveris 2 (3.6%), M. intracellulare type, M. chelonae, M. kansasii type V, M. gallinarum, M. wolinskyi. Respectively, 1 (1.8%) and 6 (10.7%) species were not identified.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2006년도 제27회 추계학술대회논문집
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• pp.71-74
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• 2006

본 논문은 미국의 우주개발과 함께 고안되어 여러 산업에 걸쳐 적용된 바 있는 확률적 위험 분석(probabilistic Risk Assessment; PRA) 기법의 역사와 내용을 소개하고 현재 항공우주연구연이 개발하고 있는 소형위성발사체(KSLV-I)의 추진기관에 대하여 그 흐름대로 적용하여 실제 기술적 위험 관리와 신뢰도 분석에 적용 가능함을 확인하고 한다.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1999년도 봄 학술발표회 논문집
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• pp.3-10
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• 1999

This paper presents probabilistic risk assessment system model and methods for general construction projects and demonstrates the applicability of the approach to a specific subway construction project. The proposed system model entitled Integrated Risk Assessment System(IRAS) for construction projects is composed of four steps, which is newly reorganized and improved in order to be easily adjusted for a systematic PRA of construction projects. Based on the proposed model, and integrated prototype software is then developing for computer-aided PRA of construction projects under the environment of the graphic-user interface, which will be successfully applied to construction projects.