• Environmental Analysis Health and Toxicology
• /
• v.24 no.1
• /
• pp.17-23
• /
• 2009

Nanotechnology, one of the technologies that forms the core of the recent scientific innovation, is used much in our real lives. Especially products that use nano silver are being sold, with its positive characteristics resulting from the antibacterial effects of both nano materials and silver. But critiques have pointed out that nano silver diffused into everyday life too quickly as we do not have done any comprehensive research about the material, and worry that nano silver will affect the ecology adversely. Therefore, this research focuses on investigating the toxicity of silver nanoparticles first. To compare the effects of exposure to silver nanoparticles at pre-somite stage and somite stage(10 hours after fertilization), we exposed zebrafish embryos to silver nanoparticles(15, 30 ppt) during embryogenesis, and then checked the details of catalase enzyme activity. The hatch rate decreased in the silver nanoparticles exposed groups(15 and 30 ppt); furthermore, the hatched fishes had an abnormal notochord, damaged eyes and curved tail. The catalase activities of the 15 ppt exposed group at somite stage increased relative to those in the control group. Therefore, the silver nanoparticles could seriously damage the development of zebrafish embryos. Especially, exposure to silver nanoparticles at somite stage did severer damage than exposure since pre-somite stage did.

• Journal of The Korean Association of Information Education
• /
• v.14 no.1
• /
• pp.45-52
• /
• 2010

This paper is a research to know how to influence english lessons in a elementary school, when the class uses both video UCC and PPT to understand for an american culture and english lessons. We study 68 students in the 5th grader for 5 months. The results of the experiment research are as follows. Students of an experiment group show the advanced increase than a control group in understanding. We measure the degree of interesting about English lesson. The motive and interest in english lessons of an experiment group show the developed result. We put a question the experiment group on their opinion in video UCC utility. The experimental group answer the ratio of very positive opinion in usefulness and interest.

• Proceedings of the Ginseng society Conference
• /
• 2002.10a
• /
• pp.376-384
• /
• 2002

Object To find out which of the 27 ginsenosides isolated from Panax ginseng C.A. Mey that may inhibit the proliferation of human osteosaocoma cell line $U_2OS$. Methods Effects of each individual ginsenoside on the proliferation of $U_2OS$ cell were studied by determining the viability of cancer cells during culture with or without the presence of the test compound. DNA assay was determined by flow cytometry. Results Ginsonosides -Ro, $-Rh_l,\;-Rh_2,\;-F_1\;and\;-L_8$ at concentrations of 5 ,umol/L could obviously suppress the proliferation of $U_2OS$ cells while ginsenosides $-Rg_1,\;-F_3,$ -Rf, PPT and PT significantly inhibited the cancer cells. Flow cytometry revealed that ginsenosides $-Ro,-Rg_1-Rf,-F_1-Rh_2,PPT$ and PT induced cell cycle arrest at $G_0/G_1$ phase with obvious decrease of cell count at Sand $G_2+M$ phase, Moreover, ginsenosides $-Rf_1,-Rg_1,\;-F_1$ and PPT induced significantly high rates of cell death as compared with the control. Conclusion These data suggested that ginsenosides inhibited $U_2OS$ proliferation Via cell cycle arrest or induction of cell death.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
• /
• v.27 no.2
• /
• pp.9-15
• /
• 2021

Background: This study investigated the effects of sustained natural apophyseal glides (SNAGS) technique on lower back pain and pain disability among university students with lower back pain. Methods: A total thirty 20~30 year old university students with lower back pain were divided into two groups. A lumbar flexibility exercise was applied to the control group (n=15). The SNAGS technique group (n=15) received L1~L4 segment mobilization using SNAGS technique. Intervention was implemented for 20 minutes, 3 times a week for 3 weeks. The SNAGS were performed using belt with flexion and extension, whereas lumbar flexibility exercise included lumbar flexion and extension. Lower back disability was measured using the Korean Oswestry disability index (KODI), and pain sensitivity was measured by pain pressure threshold (PPT). The groups were assessed for lower back pain disability and pain, before and after the intervention. Results: There were significant improvements in both the KODI and PPT of the SNAGS technique group (p<.05), while the lumbar flexibility exercise group showed no significant change (p>.05). In addition, the SNAGS technique group had a statistically significant difference in KODI and PPT compared to the lumbar flexibility exercise group (p<.05). Conclusion: SNAGS technique is more effective than lumbar spine joint flexibility exercise in the improvement of lower back pain disability and pain among university students with lower back pain.

• Journal of The Korean Society of Integrative Medicine
• /
• v.9 no.2
• /
• pp.141-152
• /
• 2021

Purpose: This study aimed to compare the effects of ischemic compression (IC) therapy and extracorporeal shock wave therapy (ESWT) in patients with upper trapezius myofascial pain syndrome and to present an effective treatment method for these patients. Methods: A total of 42 patients with upper trapezius myofascial pain syndrome were randomly assigned to the IC group (n = 21) and ESWT group (n = 21). IC therapy and ESWT were performed in the IC and ESWT groups, respectively. Treatment was applied to the trigger point of the upper trapezius muscle. Visual analog scales (VAS), pain pressure threshold (PPT), range of motion, neck disability index (NDI), and fear-avoidance belief questionnaire (FABQ) were evaluated before and after the intervention to compare its effectiveness. Results: Both groups showed significant differences before and after the intervention in VAS, PPT, NDI, FABQ, flexion, extension, right side bending, and left side bending (p <.05). In addition, there were significant differences in the IC group compared to the ESWT group in VAS, PPT, and NDI (p <.05). Conclusion: IC therapy and ESWT applied to patients with upper trapezius myofascial pain syndrome are mediating methods of pain, function, and psychosocial effects. In addition, IC therapy may be a more effective mediating method for pain and dysfunction than ESWT.

• Journal of Digital Convergence
• /
• v.16 no.11
• /
• pp.543-551
• /
• 2018

This study investigated the effects of corrective exercise and TECAR on cervical alignment, pain threshold, and pain in forward head posture patients. The subject includes 30 forward head posture patients. In the intervention methods, the experimental group combined corrective exercise and TECAR treatment. Only the corrective exercise was applied to the control group. Assessments were made on cervico vertebra angle (CV angle), pain pressure threshold (PPT) and neck disability index (NDI) visual analog scale (VAS). The intervention was conducted six times a week for two weeks. Both groups showed significant differences in CV angle, PPT, NDI, and VAS. Also, PPT, NDI, and VAS excluding CV angle were significantly improved in the study group compared to the control group. These results suggest that the intervention method that combines corrective exercise and TECAR treatment has a more positive effect on pain and ADL ability of forward head posture patient.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
• /
• v.26 no.2
• /
• pp.45-53
• /
• 2020

Purpose: The purpose of this study was conducted to investigate the effects of kinesio taping and coordination exercise on the myofascial pain syndrome and shoulder function. Methods: The patients with myofascial pain syndrome were participated in this study and divided randomly 2 groups. Control group (n=22) was taken only physical therapy program. Experimental group (n=22) was taken physical therapy with Kinesio taping and coordination exercise. The Kinesio taping in experimental group applied on levator scapulae and supraspinatus. The coordination exercise performed in supine position and sitting position on 15 times during 10 seconds each positions. We measured the pain degree using visual analog scale (VAS), pain rating score (PRS), pressure pain threshold (PPT), myofascial pain subjects symptoms index and shoulder motor function using constant shoulder assessment scale; CSA before and after experiment. Results: The significant test of CSA, myofascial pain subjects symptoms index, VAS, PRS according to applying the Kinesio taping and coordination exercise between groups used ANCOVA. In the result following analysis, there was significance on VAS (F=13.071, p=.031), PRS (F=12.130, p=.014), PPT (F=7.378, p=.016), CSA (F=5.302, p=.026) between control group and experimental group. Conclusion: Then, Kinesio taping and coordination exercise has benefit on the VAS, PRS, PPT, CSA in patients with myofascial pain syndrome. So, it may suggest that Kinesio taping combined with coordination exercise will be helpful of the pain and shoulder function improvement the patients with myofascial pain syndrome.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
• /
• v.27 no.3
• /
• pp.99-105
• /
• 2021

Purpose: This study aims to report on the effect of providing customized visiting exercise, a musculoskeletal intervention method, to the elderly in the community. Methods: In this study, subjective pain was measured to evaluate pain and physical ability of the elderly, and timed up & go (TUG) test and psychological level test were performed for myofascial pain perception symptoms and gait function. Measurements were performed twice before and 4 weeks after treatment. Participants in the exercise group (n=108) performed the spine exercise, whereas those in the spine exercise group (n=108) performed the spine exercise using complex exercise program (3 times/week for 4 weeks). Results: The significant test of visual analogu scale (VAS), pain pressure threshold (PPT), TUG, psychosocial factor according to applying the exercise within groups used T-test. In the result following analysis, there was significance on VAS (p=.000), PPT (p=.000), TUG (p=.000), Psychosocial factor (Depresion; p=.000, Anxiety; p=.000) within group. Conclusion: Then, exercise has benefit on the VAS, PPT, TUG, psychosocial factor in patients with myofacial pain syndrome. So, it may suggest that exercise will be helpful of the pain, gait and psychosocial factor improvement the patients with spine pain.

• Journal of Korean Physical Therapy Science
• /
• v.28 no.3
• /
• pp.30-41
• /
• 2021

Background: The purpose of this study was to investigate the effects of WBC on the pressure pain threshold, CK and LDH after exercise-induced muscle injury. Design: A Randomized Controlled Trial. Methods: In this study, these subjects were assigned into three groups, a control group (n=10), experiment group I (n=10) and experiment group II (n=10). The subjects in experimental group I were intervened by WBC (-130℃, 3 minutes) before induced EIMD, experimental group II were intervened by WBC (-130℃, 3 minutes) after induced EIMD and control group weren't by any intervened after induced EIMD. Results: First, In the comparison of the PPT, there were significant variations with the lapse the time in three groups (p<.001) and there was a significant interaction of time and group (p<.001). In the among group comparison, the PPT of experimental group II was significantly larger than those of other groups (p<.01). Second, In the comparison of the CK, there were significant variations with the lapse the time in three groups (p<.001) and there was a significant interaction of time and group (p<.001). In the among group comparison, the CK of experimental group II was significantly smaller than those of other groups (p<.001). Third, In the comparison of the LDH, there were significant variations with the lapse the time in three groups (p<.01) and there was a significant interaction of time and group (p<.001). In the among group comparison, the LDH of experimental group II was significantly smaller than those of other groups (p<.001). Conclusion: The above results revealed that the WBC intervention after an exercise had a positive effect of muscle function after EIMD.

• Journal of Oral Medicine and Pain
• /
• v.47 no.2
• /
• pp.87-94
• /
• 2022

Purpose: This study aimed to evaluate the differences between clinical and quantitative sensory testing (QST) results among persistent idiopathic dentoalveolar pain (PIDP), inflammatory dental pain, and control group subjects to identify discriminative clinical features for differential diagnosis. Methods: Thirty-three patients (5 PIDP-a without surgical procedures 10 PIDP-b with surgical procedures, 8 dental pain patients, and 10 controls) were evaluated for clinical features and QST results. Cold pain threshold, heat pain threshold, mechanical pain threshold (MPT), mechanical pain sensitivity, and pressure pain threshold (PPT) were performed. Psychological factors were assessed using Symptom Checklist-90-Revision (SCL-90-R) and a chart review was conducted to evaluate additional discriminative clinical features such as pain quality and treatment prognosis. Results: The dental pain group had lower PPT than the PIDP-b and the control group. The PIDP-a group showed higher MPT and PPT than the PIDP-b and dental pain group but the difference was not statistically significant. Differences in SCL-90-R SOM (Somatization), O-C (obsessive-compulsive), ANX (anxiety), and PSY (Psychoticism) values were statistically significant among groups. PIDP-a and PIDP-b groups showed remaining symptoms after treatment and the pain tended to spread widely, whereas, in toothache patients, symptoms disappeared after treatment. However, factors that confound the diagnosis, such as an increase in pain during chewing and a decrease in the pain threshold at the affected site, could also be identified. Conclusions: PIDP and dental pain groups have distinct clinical symptoms, but there are also factors that cause confusing in diagnosis. Therefore, various clinical examination results should be carefully reviewed and comprehensively evaluated in the differential diagnosis process.