• Bulletin of the Korean Chemical Society
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• 제26권6호
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• pp.1001-1004
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• 2005

• Asian Pacific Journal of Cancer Prevention
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• 제15권3호
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• pp.1145-1148
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• 2014

Background: Single pegylated liposomal doxorubicin (PLD) is commonly used as a salvage treatment in platinum-resistant ovarian cancer, fallopian tube cancer and primary peritoneal adenocarcinoma (PPA) with a satisfactory outcome. However, the data for second generation PLD administered in this setting are still limited. We conducted a retrospective study to evaluate the outcome of patients who received single-agent second generation PLD (LIPO-DOX) after the development of clinical platinum resistance. The study period was between March 2008 and March 2013. LIPO-DOX was administered intravenously 40 $mg/m^2$ every 28 days until disease progression, but for not more than six cycles. The response rate was evaluated using the Gynecologic Cancer Intergroup (GCIG) criteria while the toxicity was evaluated according to WHO criteria. Twenty-nine patients met the inclusion criteria in the study period with an overall response rate of 13.8%. The median progression free survival and overall survival were three and eleven months, respectively. With the total of 96 cycles of chemotherapy, the patients developed grades 3 and 4 hematologic toxicity as follows: anemia, 0%, leukopenia, 9.6%, neutropenia, 32.3% and thrombocytopenia, 0%. In conclusion, the single agent second generation PLD demonstrated modest efficacy in patients with platinum-resistant ovarian cancer, fallopian tube cancer and PPA without serious toxicity.

• 시스템엔지니어링학술지
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• 제9권2호
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• pp.37-53
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• 2013

With rapid growth of the world plant market, an increasing attention is paid on the plant engineering. Up to present time, Korean plant engineering technology has been concerned with the down stream part of the plant engineering, so called EPC, considered as a lower value chain compared with the up stream, composed of FEED(Front End Engineering Design) and PMC(Project Management Consultancy). In other words, a key issue for Korean plant industry is how to catch up the FEED technology, currently occupied by the advanced countries. In this paper, we propose an SE(Systems Engineering) approach, conventionally applied for aerospace and defense industry, to the FEED for plant engineering. Specifically, we proposed a new SE process composed of: 1) SPA matrix for reverse systems engineering, and 2) PPA matrix for forward systems engineering. To illustrate the proposed method, a case study for an environmental plant is performed.

• Bulletin of the Korean Chemical Society
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• 제32권7호
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• pp.2311-2315
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• 2011

Alumina supported polyphosphoric acid (PPA/$Al_2O_3$) was successfully prepared by impregnation of alumina support by polyphosphoric acid and characterized using FT-IR spectroscopy, the $N_2$ adsorption/desorption analysis (BET), thermal analysis (TG/DTG), and X-ray diffraction (XRD) techniques. The catalytic behavior of this new solid acid supported heterogeneous catalyst was checked in the synthesis of 14-aryl-14H-dibenzo[a, j]xanthenes by cyclocondensation reaction of ${\beta}$-naphthol and aryl aldehydes under solvent-free conditions. The results showed that the novel catalyst has high activity and the desired products were obtained in very short reaction times with high yields. Moreover, the catalyst can be easily recovered by filtration and reused at least three times with only slight reduction in its catalytic activity.

• Advances in Automotive Engineering
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• 제1권1호
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• pp.143-152
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• 2018

In this study an economical image stitching algorithm for use in automotive industry is developed for retrofittable panoramic image assistance applications. The aim of this project is to develop a driving assistance system known as Panoramic Parking Assistance (PPA) which is cheap, retrofittable and compatible for every type of automobiles. PPA generates bird's eye view image using cameras installed on the automobiles. Image stitching requires to get bird's eye view position of the vehicle. Panoramic images are wide area images that cannot be available by taking one shot, attained by stitching the overlapping areas. To achieve correct stitching many algorithms are used. This study includes some type of these algorithms and presents a simple one that is economical and practical. Firstly, the mathematical model of a wide view of angle camera is provided. Then distorted image correction is performed. Stitching is implemented by using the SIFT and SURF algorithms. It has been seen that using such algorithms requires complex image processing knowledge and implementation of high quality digital processors, which would be impracticle and costly for automobile use. Thus a simpler algorithm has been developed to decrase the complexity. The proposed algorithm uses one matching point for every couple of images and has ease of use and does not need high power processors. To show the efficiency, images coming from four distinct cameras are stitched by using the algorithm developed for the study and usability for automotive application is analyzed.

• 대한토목학회논문집
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• 제12권2호
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• pp.151-159
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• 1992

근거리 사진측량에서 정오차의 보정은 정확도 향상에 중요한 영향을 미치며, 특히 비측량용사진기를 정밀측량에 이용하기 위해서는 정오차에 대한 보정이 선행되어야 한다. 이를 위해 비측량용사진기에 지표를 설치하고 collimator검정방법에 의해 렌즈의 PPS, PPA, EFL, CFL 및 각 상한별 렌즈의 방사방향 왜곡계수를 구하였고, plumb line 검정방법에 의해서도 렌즈의 방사방향 및 접선방향에 대한 왜곡계수를 구하여 정오차 보정을 효율적으로 시도하였다. 이 검정된 비측량용사진기를 이용하여 근접사진측량을 실시하고, 정오차를 보정하므로써 정확도 향상을 꾀할 수 있었다.

• 한국응용과학기술학회지
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• 제25권2호
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• pp.151-159
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• 2008

The flame-retardant coatings were prepared by blending the synthesized triphosphorus modified polyester in the previous paper and hexamethylene diisocyanate-trimer and curing it at room temperature. The characterization of the films of the prepared coatings was performed. It was confirmed that no deterioration of physical properties of PU coatings was observed with the increasing phenylphosphonic acid (PPA) contents. Flame retardancy was tested by a $45^{\circ}$ Meckel burner method and LOI method. With the $45^{\circ}$ Meckel burner method, CATBTP-20C and CATBTP-30C that contain 20 wt% and 30 wt% of PPA, flame retarding component, respectively, showed the first grade flame retardancy with $2.8{\sim}3.9\;cm$ of char length ; and, with LOI method, they exhibited a good flame retardancy as a range of $30{\sim}32%$ of combustion values.

• ETRI Journal
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• 제44권3호
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• pp.400-412
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• 2022

In cognitive radio networks (CRNs), the computational complexity of resource allocation algorithms is a significant problem that must be addressed. However, the high computational complexity of the optimal solution for tackling resource allocation in CRNs makes it inappropriate for use in practical applications. Therefore, this study proposes a power-based pricing algorithm (PPA) primarily to reduce the computational complexity in downlink CRN scenarios while restricting the interference to primary users to permissible levels. A two-stage approach reduces the computational complexity of the proposed mathematical model. Stage 1 assigns subcarriers to the CRN's users, while the utility function in Stage 2 incorporates a pricing method to provide a power algorithm with enhanced reliability. The PPA's performance is simulated and tested for orthogonal frequency-division multiplexing-based CRNs. The results confirm that the proposed algorithm's performance is close to that of the optimal algorithm, albeit with lower computational complexity of O(M log(M)).

• Asian-Australasian Journal of Animal Sciences
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• 제24권7호
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• pp.974-981
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• 2011

This study was designed to re-evaluate the dietary methionine requirement by means of the plasma methionine and ammonia concentrations in surgically modified rainbow trout, Oncorhynchus mykiss. A total of 35 rainbow trout averaging $505{\pm}6.5$ g (initial body weight, mean${\pm}$SD) were randomly distributed into seven groups with five fish in each group. After 48 h of feed deprivation, each group of fish was fed one of seven L-amino acid based diets containing 0.5% cystine and graded levels of methionine (0.25, 0.40, 0.50, 0.60, 0.70, 0.80 or 0.95% of diet, dry matter bases) by intubation at 1% body weight on dry matter basis. Blood samples were taken at 0, 5 and 24 h after intubation. Post-prandial plasma free methionine concentrations (PPmet, 5 h after intubation) and post-absorptive plasma free methionine concentrations (PAmet, 24 h after intubation) of fish fed diets containing 0.60% or higher methionine were significantly (p<0.05) higher than those of fish fed diets containing 0.50% or lower methionine. PPmet and PAmet in fish fed diets containing 0.60% or higher methionine were not significantly different except PPmet of fish fed diet containing 0.95% methionine. Post-prandial plasma ammonia concentrations (PPA, 5 h after intubation) of fish fed diets containing 0.70% or higher methionine were significantly higher than those of fish fed diets containing 0.60% or lower methionine, and PPA of fish fed diets containing 0.25 and up to 0.60% methionine were not significantly different from each other. Broken-line model analyses on PPmet, PAmet, and PPA indicated that the dietary methionine requirement of rainbow trout was between 0.59 (1.69) and 0.67 (1.91) % of diets (% dietary protein bases) when the diets contained 0.5% cystine.

• Journal of Applied Biological Chemistry
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• 제53권3호
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• pp.154-161
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• 2010

도화를 기능성 화장품 소재로 활용하기 위하여 미백 및 주름개선 효과를 검증한 후 화장품 소재로서의 가능성을 검증하였다. 미백효과를 확인하기 위하여 tyrosinase 저해활성을 측정한 결과 도화 열수 및 에탄올 추출물 1,000ppm에서 각각 54.0, 58.3%의 저해활성을 나타내었으며, 멜라노마 세포에서의 tyrosinase 저해활성을 측정한 결과 도화 에탄올 추출물 100ppm에서 40.0%의 저해활성을 나타내였다. 또한 멜라노마 세포에서의 멜라닌 생합성 저해율을 확인한 결과 도화 에탄올 추출물 100ppm에서 56.5%의 효과를 나타내어 도화 에탄올 추출물의 미백효과가 가장 우수하였다. 주름개선 효과 측정으로 elastase 저해활성을 측정한 결과 도화 아세톤 추출물 1,000ppm에서 57.0%의 저해활성을 나타내었으며, collagenase 저해활성을 측정한 결과 도화 아세톤 1,000ppm에서 48.0%의 저해활성을 나타내었다. 또한 섬유아세포를 이용한 collagen 생합성량을 측정한 결과 도화 아세톤 추출물 100ppm에서 41.0%의 효과를 나타내어 도화 아세톤 추출물의 주름개선 효과가 가장 우수하였다. 이상의 결과로 미루어 보아 도화 추출물의 미백 및 주름개선 효과가 있음을 확인할 수 있었고, 기능성 화장품 소재로서의 가능성을 확인할 수 있었다.