• 대한두경부종양학회:학술대회논문집
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• 대한두경부종양학회 1999년도 추계 학술대회
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• pp.271.1-271.1
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• 1999

• 대한토목학회논문집
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• 제12권1호
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• pp.51-58
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• 1992

본 연구의 목적은 피로파괴에 대한 해양 구조물의 체계신뢰도해석에 관한 연구이다. 제 2차 모멘트 신뢰도 방법에 기초하여 제안한 새로운 두 방법을 사용하였는데, 하나는 개선된 제 1계 신뢰도방법(IFORM)이고 다른 하나는 수정된 Probabilistic Network Evaluation Technique(MPNET)이다. 이상화된 병렬부재모형을 사용하여 부재당 다수의 연결절점으로 구성된 여러 부재들을 가진 경우에 대하여 진전하는 피로파괴에 대한 신뢰도해석들을 수행하였다. 수치해석결과로부터 본 논문에서 사용한 방법들이 재래적인 방법인, 제 1계 신뢰도방법(FORM)과 PNET 방법보다 더 정확한 결과를 얻을 수 있었다. 이러한 경향은 체계의 파괴모우드 수가 증가됨에 따라 더욱 분명하였다.

• Investigative Magnetic Resonance Imaging
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• 제14권2호
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• pp.145-150
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• 2010

소아에서 췌장의 악성 종양은 매우 드물게 발생하고 있으며, 특히 악성 신경내분비 종양은 더더욱 드물다. 저자들은 16세 소아 환자에서 발생한 비기능성 악성 신경내분비 종양의 증례를 경험하여 CT와 MRI 소견을 보고하고자 한다. 췌장 두부에서 발생한 고형 종양으로 조영증강 MRI의 문맥기에서 지연기로 갈수록 조영증강이 잘 되고, 주변의 혈관 침습, 총담관 폐색, 림프절병증 등 악성 소견을 동반할 때 췌장의 비기능성 악성 신경내분비 종양을 감별 진단에 포함하여야 한다.

• 대한세포병리학회지
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• 제9권1호
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• pp.21-28
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• 1998

Cytologic evaluation of cerebrospinal fluid(CSF) is an effective tool in diagnosing many disorders involving the central nervous system(CNS). CSF examination has been found to be of particular value in the diagnosis of metastatic carcinoma, lymphomatous or leukemic involvement of CNS and certain primary CNS tumors. As a survey of metastatic tumors to CSF and an evaluation of the preparation techniques increasing cellular yield in our laboratory, 713 CSF specimens examined between July 1995 and April 1997(1 year 10 months), were reviewed. There were 75 positive and 5 suspicious cases, the latter have had no evidence of tumors clinically. Primary tumors of 75 positive cases were classified as follows; 4(5.3%) as primary brain tumors, 40(53.3%) as secondary carcinomas, 13(17.3%) as leukemias, and 18 (24.0%) as lymphomas. The most common primary site of metastatic carcinomas was the lung in 17 cases(42.5%) followed by the stomach in 13(32.5%), breast in 8 (20.0%), and unknown primary in 2(5.0%). Four primary brain tumors were 3 cerebellar medulloblastomas and a supratentorial primitive neuroectodermal tumor (PNET). All 40 metastatic carcinomas were adenocarcinoma presented as single cells or cell clusters. Although signet ring cells were frequent in the cases of gastric primary cancers, no significant cytologic differences according to the primary site were observed. The cytologic features of leukemia and lymphoma were characterized by hypercellular smears presenting as individual atypical cells with increased N/C ratio, presence of nucleoli, and nuclear protrusions. In medulloblastomas and PNET, the principal cytologic findings were small undifferentiated cells arranged singly or in loose clusters with occasional rosettoid features. This study suggests that the CSF cytology is useful in the diagnosis of malignancy, especially metastatic extracranial tumors and the diagnostic accuracy can be improved by increasing cellular yield using cytocentrifuge.

• Journal of Korean Neurosurgical Society
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• 제37권3호
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• pp.193-196
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• 2005

Objective: Strategies for managing supratentorial primitive neuroectodermal tumors(PNETs) in children include surgical resection, craniospinal irradiation and chemotherapy. This study is performed in order to compare the efficacy of various methods of treatment and to describe its optimal management. Methods: We have reviewed all medical records and pathology slides of six children(four males and two females) with supratentorial PNET from November, 1987 to May, 2003. The extent of resection was confirmed by computed tomography and magnetic resonance studies. Results: The patients were aged 1 to 13 years and treated postoperatively with/without adjuvant therapy. Tumor location included was four cortical, one gangliobasal, and one pineal region. The presenting symptoms and signs consisted of increased intracranial pressure and focal neurological deficits such as seizure and hemiparesis. The treatment consisted of surgical resection alone in one patient, postoperative radiotherapy in one patient, postoperative chemotherapy in one, and postoperative radiotherapy with chemotherapy in three. Five patients lived more than 12 months after diagnosis and one patient among them has been living more than 5 years after diagnosis. Conclusion: We can improve the survival and prognosis of supratentorial PNET patients by radical gross total resection of tumor followed by craniospinal irradiation and aggressive chemotherapy. First of all, gross total resection of tumor is the most important among many factors.

• Structural Engineering and Mechanics
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• 제63권6호
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• pp.799-808
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• 2017

Failure of a redundant long-span bridge is often described by innumerable failure modes, which make the structural system reliability analysis become a computationally intractable work. In this paper, an innovative procedure is proposed to efficiently identify the dominant failure modes and quantify the structural reliability for a long-span bridge system. The procedure is programmed by ANSYS and MATLAB. Considering the correlation between failure paths, a new branch and bound operation criteria is applied to the traditional stage critical strength branch and bound algorithm. Computational effort can be saved by ignoring the redundant failure paths as early as possible. The reliability of dominant failure mode is computed by FORM, since the limit state function of failure mode can be expressed by the final stage critical strength. PNET method and FORM for system are suggested to be the suitable calculation method for the bridge system reliability. By applying the procedure to a CFST arch bridge, the proposed method is demonstrated suitable to the system reliability analysis for long-span bridge structure.

• Journal of Korean Neurosurgical Society
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• 제30권5호
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• pp.647-651
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• 2001

Trilateral retinoblastoma is a syndrome involving midline intracranial malignancies in children with the heritable form of retinoblastoma. It is rare and usually lethal in spite of aggressive treatments. We report a case of trilateral retinoblastoma with review of the literature to gain further insight into this uncommon disease.

• Journal of Korean Neurosurgical Society
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• 제58권6호
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• pp.557-559
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• 2015

Medulloblastoma is a common pediatric tumor typically diagnosed before the age of fifteen. Initial therapy includes surgical resection and radiation of the entire neuro-axis. Recurrence is common and typically occurs within 2 years of initial diagnosis. Those fitting Collin's Law is considered tumor-free. We report a case of single supratentorial recurrence 13 years after initial diagnosis. Here we present a 22 year old male presenting 13 years after initial diagnosis with isolated septum pellucidum recurrence. He underwent complete resection of the tumor. Medulloblastoma is a common in the pediatric population. Late recurrence to the ventricular system is uncommon. Long term follow-up is recommended in these patients.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1992년도 봄 학술발표회 논문집
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• pp.51-57
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• 1992

The primary objective of this study is the development of second moment methods for the efficient reliability evaluations of structural systems. Two methods are presented. One is the improved first order reliability method (IFORM), and the other is the modified probabilistic network evaluation technique (MPNET). For the purpose of verifying the proposed methods, example analyses are carried out on several cases with two failure modes, a plane frame structure involving three failure modes and simplified parallel member models for fatigue reliability evaluations of offshore structures. Numerical results indicate that the effectiveness of the proposed methods over the conventional ones (i.e., the FORM and the PNET) increases very significantly as the number of failure modes of the system increases.

• Advances in pediatric surgery
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• 제12권1호
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• pp.17-23
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• 2006

A 3-year-old girl with a primitive neuroectodermal tumor (PNET) and a 6-yearold girl with acute lymphoid leukemia were referred to us because of problems with their implantable central venous ports (Port-A-Cath$^{(R)}$). On physical examination, the ports were upside-down, so a needle could notbe inserted through the membrane of the port. Right lateral side view of the chest radiogram confirmed port inversion in both cases. At operation, the ports were inverted and the transfixing sutures were totally absorbed. The ports were rotated 180 degrees and anchoring sutures placed.