• Radiation Oncology Journal
• /
• v.11 no.1
• /
• pp.83-90
• /
• 1993

During the period from January, 1975, to June, 1989, one hundred patients with histopathologically proven polymorphic reticulosis in the upper respiratory tract were treated with radiation therapy and the analysis of treatmemt results was undertaken. One hundred patients (69 males, 31 females) with a mean age of 46 years (range 12-79 years) were presented. Nasal cavity was the most frequent site of involvement ($56{\%}$), and 44 cases had multifocal sites of involvement. The incidence of cervical lymph node metastasis at initial diagnosis was $24{\%}$. Staging was determined by Ann-Arbor classification, retrospectively. The number of patients of stage IE, IIE, IIIE and IVE were 35, 60, 1, and 4, respectively. The overall 5 year actuarial survival rates were $38.4{\%}$. The difference in 5 year survival rates between patients with stage IE and IIE, with solitary and multiple, with CR and PR after irradiation were significant statistically. For the analysis of failure patterns, failure sites include the following: local failure alone (30/55=$54.6{\%}$), systemic failure alone (9/55=$16.4{\%}$), both local and systemic failure (16/55=$29.0{\%}$). Retrograde slide review was available in 29 cases of PMR with respect to histopathologic bases, and immunohistochemical studies were performed using MT1 and DACO-UCHL-1 as T-cell markers, MB2 as a B-cell marker and alpha-1-antichymotrypsin as a histiocytic markers. All that 29 cases showed characteristic histologic features similar to those of peripheral T-cell lymphoma and showed positive reactio to the T-cell marker. These findings suggest strongly that quite a significant portion of PMR may be in fact T-cell lymphoma.

• Journal of Korean Medicine Rehabilitation
• /
• v.18 no.1
• /
• pp.125-140
• /
• 2008

Objectives : The purpose of this study was to investigate the effect of Progressive Muscle Relaxation(PMR) on stress and muscle relaxation in healthy people. Methods : Sample group of 14 healthy subjects had been treated by progressive muscle relaxation for 10 days. Control group of 14 healthy subjects were not treated during the same period. Outcomes were assessed by Meridian-Electromyograph(MEMG), Heart Rate Variability(HRV), Stress Reaction Inventory(SRI). Results : The contraction and fatigue of erector spinae muscle by MEMG had decreased significantly in Sample group. There was no significant difference between two groups in the HRV and SRI. Conclusions : Further studies analysing PMR effect on stress and muscle relaxation are needed.

• BioChip Journal
• /
• v.12 no.4
• /
• pp.304-308
• /
• 2018

Atopic disease is caused by a complex combination of environmental factors and genetic factors, and studies on influence of exposure to various environmental factors on atopic diseases are continuously reported. However, the exact cause of atopic dermatitis is not yet known. Our study was conducted to analyse the association of SNPs with the development of atopic disease in a small cohort. Samples were collected from the Mothers' and Children's Environmental Health (MOCEH) study and 192 cord blood DNA samples were used to identify incidence of atopy due to influence of exposure to environmental factors. Genetic elements were analysed using a precision medicine research (PMR) array designed with various SNPs for personalized medicine. Case-control analysis of atopy disease revealed 253 significant variants (p<0.0001) and SNPs on five genes (CARD11, ZNF365, KIF3A, DMRTA1, and SFMBT1) were variants identified in previous atopic studies. These results are important to confirm the genetic mutation that may lead to the onset of foetal atopy due to maternal exposure to harmful environmental factors. Our results also suggest that a small-scale genome-wide association analysis is beneficial to confirm specific variants as direct factors in the development of atopy.

• Journal of Bio-Environment Control
• /
• v.29 no.4
• /
• pp.406-413
• /
• 2020

This study was conducted to find out optimum fruiting node order, pinching node order, and harvesting time in hydroponics using coir substrates to produce high quality melon (Cucumis melo L.) fruit. Three plants per coir slab (100 × 20 × 10 cm) were planted for each treatment. Yamazaki standard nutrient solutions for melon were supplied with 1.8, 2.0, and 2.3 dS·m^-1 at the early, middle (fruit enlargement step), and late growth stages, respectively. Two cultivars of 'PMR Dalgona' and 'Earl's Aibi' were used for fruiting node order and pinching node order experiments. Fruiting node treatments were conducted three replications (8-10 ^th, 11-13 ^th, and 14-15 ^th nodes) and pinching node treatments treated with three replications (18 ^th, 21 ^th, and 24 ^th nodes). Two cultivars of 'PMR Dalgona' and 'Earl's Crown' were used for fruit harvesting time experiment and treated with in four replications (45, 50, 55, and 60 days after fruiting). In growth characteristics, the leaf width and leaf area of 'PMR Dalgona' were the greatest 28.2 cm and 10,845 ㎠. Respectively, 11-13 ^th fruiting nodes or more. The node length of 'Earl's Aibi' was the longest by 147.6 cm at 11-13 ^th fruiting nodes. For fruit quality characteristics, the fruit weight of 'Earl's Aibi' at 11-13 ^th fruiting node fruiting was the greatest by 2.0 kg. The soluble solids content (SSC) of 'PMR Dalgona' was the highest by 14.5 °Brix at 8-10 ^th nodes in fruiting node orders and 14.5 °Brix at the 24 ^th pinching node order, respectively with significant difference. The SSC tends to increase in the same for both cultivars of 'PMR Dalgona' and 'Earl's Aibi' as the position of fruiting node was lower. The SSC and fruit weight of melon harvested at 55-60 days after fruiting was the best. From the results of this study, most of SSC tends to increase in the lower position of fruiting node order and the higher pinching node order, whereas the fruit weight shows a tendency of increasing with higher fruiting node. In addition, the SSC of fruit increased as the number of days after fruiting increased, and further research is needed for more various cultivars. In melon hydroponics using coir substrates, it is needed to figure out the characteristics of each cultivar to determine optimum fruiting node order, pinching node order, and fruit harvest time.

• Journal of the Korean Chemical Society
• /
• v.19 no.3
• /
• pp.149-155
• /
• 1975

Pivalic acid, which has a globular shape and is a plastic crystal, has been examined by means of temperature-dependent with-line proton magnetic resonance spectroscopy. Results of temperature-dependent line width, second moment, and spin-lattice relaxation time studies of pivalic acid were interpreted in terms of dynamic behavior and hydrogen bonding. The dynamic behavior consists of superimposed reorientation of the methyl groups about their three-fold axes$(C_3) and of the molecule about the central C-C bond(C_3'),$ general molecular reorientation about the center of gravity, and molecular self-diffusion. Activation energies for the motional processes have been obtained from line width measurements using the modified Bloembergen, Purcell, and Pound theory and from spin-lattice relaxation time measurements. The results were compared with the Pople-Karasz theory of fusion and the agreement was found to be poor. The discrepancy was interpreted in terms of hydrogen bonding in this molecule.

• Journal of Korean Ophthalmic Optics Society
• /
• v.11 no.3
• /
• pp.225-229
• /
• 2006

In our angle configuration, several peculiar characteristic behaviors of MR could be observed, the mixing of positive MR(PMR) and negative MR(NMR) in the inclined sample was observed. The complete mixing angle, ${\phi}_{mix}$ as a function of inclination angle, ${\theta}$ was observed to fit well to the relation of ${\phi}_{mix}=tan^{-1}(1+tan{\theta})$ in nickel films. The above theoretical relation was obtained by decomposing the magnetic field into the components parallel and perpendicular to the current flow and identifying ${\phi}_{mix}$ as the angle satisfying that the above two components of magnetic field were identical. We also observed that the data of ${\phi}_{mix}$ did not satisfy the above theoretical relation in the iron film. This was explained by the fact that the growth direction in the iron film was an intermediate direction of magnetization, while the growth direction in the nickel film was an easy axis of magnetization.

• Korean Journal of Pharmacognosy
• /
• v.17 no.1
• /
• pp.62-66
• /
• 1986

Acanthopanax koreanum Nakai (Araliaceae) is a indigenous medicinal plant growing throughout Jeju-Do in Korea. The plant extract is used in rheumatism, tonic, paralysis and sedative agent. From the roots of A. koreanum, lignan compounds, a diterpenoid, and a polyacetylene compound were isolated and their structures were elucidated by using IR, PMR, CMR and MS spectral data.

• Research in Plant Disease
• /
• v.18 no.1
• /
• pp.29-34
• /
• 2012

Powdery mildew and root-knot nematode are very important diseases occurred in cucurbits. This study was conducted to evaluate the resistance of commercial cucurbit cultivars (21 cultivars of cucumber, 9 cultivars of watermelon, 7 cultivars of oriental melon, and 2 cultivars of melon) to powdery mildew and root-knot nematode. At 60 days after transplanting, disease severity of powdery mildew of commercial cucurbit cultivars was investigated. Two cucumber cultivars, 'Gangryeogsamcheok' and 'Sunhobaegchimdadagi' were moderately resistant but the rest of cucumber cultivars were susceptible to powdery mildew. All examined watermelon and oriental melon cultivars were susceptible to powdery mildew, while two melon cultivars ('PMR Turbo' and 'PMR Victory') were resistant. At 45 days after inoculation of seedlings, disease severity of root-knot nematode of commercial cucurbit cultivars were investigated. One cucumber cultivars, 'Baegbongdadagi' was moderately resistant and the others were susceptible to root-knot nematode. In case of watermelon, 'Dalgonakkul' was resistant and the others were moderately resistant or susceptible to root-knot nematode. All examined oriental melon and melon cultivars were susceptible to root-knot nematode. On these results, we recommend that resistant cultivars to powdery mildew and/or root-knot nematode will be more suitable in cultivation of cucurbits for organic farming.

• Microbiology and Biotechnology Letters
• /
• v.36 no.4
• /
• pp.320-325
• /
• 2008

Some anti-dementia, cardiovascular and antioxidant functionalities of Korean traditional alcoholic beverages were characterized. Anti-dementia acetylcholinesterase inhibitory activities were generally not detected or low except BHS-ju (19.5%) and buthyrylcholinesterase inhibitory activities were also show below 1.0%. However, $\beta$-Secretase inhibitory activities were high in PMR-ju (42.5%), WJY-ju (41.6%) and SSJ-ju (42.9%). Antihypertensive angiotensin I-converting enzyme inhibitory activities was the highest in YON-ju (85.6%), however fibrinolytic activities were not detected in all traditional alcohol beverages. Furthermore, antioxidant activities were very high in SBB-ju (72.2%) and GMB-ju (67.9%), however SOD like activities generally were show below 20%.

• The Plant Pathology Journal
• /
• v.34 no.3
• /
• pp.182-190
• /
• 2018

Powdery mildew caused by the obligate biotrophic fungus Podosphaera xanthii poses a serious threat to melon (Cucumis melo L.) production worldwide. Frequent occurrences of the disease in different regions of South Korea hints at the potential existence of several races which need to be identified. The races of five isolates collected from different powdery mildew affected regions were identified based on the pathogenicity tests of these isolates on eight known differential melon cultigens namely, SCNU1154, PMR 45, WMR 29, PMR 5, MR-1, PI124112, Edisto 47 and PI414723. None of the isolates have shown same disease responses to those of the known races tested in this study and in previous reports on these identical differential melon cultigens. This indicates that the tested uncharacterized isolates are new races. Among the isolates, the isolates from Hadong, Buyeo, Yeongam and Gokseong have shown same pathogenicity indicating the possibility of these isolates being one new race, for which we propose the name 'race KN1'. The isolate of Janghueng have also shown unique disease response in the tested differential melon cultigens and hence, we identified it as another new race with a proposed name 'race KN2'. Report of these new races will be helpful in taking effective control measures in prevalent regions and for future breeding programs aimed at developing varieties that are resistant to these race(s).