• Journal of Institute of Control, Robotics and Systems
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• v.22 no.1
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• pp.59-65
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• 2016

As modern electronic devices get smaller and smaller, high-resolution, large Field-Of-View (FOV), fast, and cost-effective 3-dimensional (3-D) measurement is requested more and more. In particular, defect inspection machines using machine-vision technology nowadays require 3-D inspection as well as the conventional 2-D inspection. Phase Measuring Profilometry (PMP) is one of the fast non-contact 3-D shape measuring methods currently being extensively investigated in the electronic component manufacturing industry. The PMP system is well known and is successfully applied to measuring complex surface profiles with varying reflectance properties. However, for highly reflective surfaces, such as Ball Grid Arrays (BGAs), it has difficulty accurately measuring 3-D shapes. In this paper, we propose a new fast optical system that can eliminate the highly reflective saturated regions in BGA ball images. This is achieved by utilizing four Low Intensity Grating (LIG) images together with the conventional High Intensity Grating (HIG) images. Extensive experiments using BGA samples show a repeatability of under ${\pm}20um$ in standard deviation, which is suitable for most 3-D shape measurements of BGAs.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2000.11a
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• pp.19-22
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• 2000

Noncontact measuring methodology of 3-dimensional profile using CCD camera are very attractive because of it's high measuring speed and its's high sensitivity. Especially, when projecting a grid pattern over the object the captured image have 3 dimensional information of the object. Projection moire extract 3-D information with another grid pattern in front of CCD camera. However phase measuring profilometry(PMP) obtain similar results without additional grid pattern. In this paper, new method for grid pattern generation system by polygonal mirror and Laser Diode. This system is applied the projection moire and the PMP.

• Journal of Genetic Medicine
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• v.12 no.1
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• pp.25-30
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• 2015

Purpose: Charcot-Marie-Tooth disease (CMT) is a peripheral neuropathy mainly divided into CMT type 1 (CMT1) and CMT2 according to the phenotype and genotype. Although molecular pathologies for each genetic causative have not been revealed in CMT2, the correlation between cell death and accumulation of misfolded proteins in the endoplasmic reticulum (ER) of Schwann cells is well documented in CMT1. Establishment of in vitro models of ER stress-mediated Schwann cell death might be useful in developing drug-screening systems for the treatment of CMT1. Materials and Methods: To develop high-throughput screening (HTS) systems for CMT1, we generated cell models using transient expression of mutant proteins and chemical induction. Results: Overexpression of wild type and mutant peripheral myelin protein 22 (PMP22) induced ER stress. Similar results were obtained from mutant myelin protein zero (MPZ) proteins. Protein localization revealed that expressed mutant PMP22 and MPZ proteins accumulated in the ER of Schwann cells. Overexpression of wild type and L16P mutant PMP22 also reduced cell viability, implying protein accumulation-mediated ER stress causes cell death. To develop more stable screening systems, we mimicked the ER stress-mediated cell death in Schwann cells using ER stress inducing chemicals. Thapsigargin treatment caused cell death via ER stress in a dose dependent manner, which was measured by expression of ER stress markers. Conclusion: We have developed genetically and chemically induced ER stress models using Schwann cells. Application of these models to HTS systems might facilitate the elucidation of molecular pathology and development of therapeutic options for CMT1.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.05a
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• pp.584-587
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• 2018

Many viruses including mouse hepatitis virus, corona, measles, and sidbis viruses are known as causative virus of inducing demyelination which means destruction of myelination in nervous system of mice. The purpose of this study is to investigate processing of myelination by co-culture of Schwann cells and neuronal cells and demyelination induced by infection of sindbis virusin rat. Schwann cells and neuronal cells from dorsal root ganglion (DRG) in embryos (E16) of rat were cultured in vitro respectively. The purified neuronal cells with anti-mitotic agents and purified Schwann cells were co-cultured. After that, infection of sindbis virus into this myelinated co-culture system was performed. Myelination and demyelination process were observed using antibody of myelin basic protein meaning presence of myelination.We identified myelination and demyelination processing using antibody of peripheral myelin protein 22 (PMP 22) meaning presence of myelinated neuron. This study was supported by the Basic Research Program through the National Research Foundation (NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2015R1C1A1A01053484 and 2017R1A2B3005753).

• Transactions of the Korean Society of Mechanical Engineers B
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• v.22 no.11
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• pp.1635-1646
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• 1998

The present study investigated the effects of geometric parameters considered on the performance of an automotive scroll compressor by assuming ideal, semi-real and real gases for R-134a. The geometric parameters were center thickness of scroll, height of scroll and the size of discharge port. Fourth-order Runge-Kutta method was applied to solve the thermodynamic equations, leaking rate equation and the equation of motion of discharge valve for ideal, semi-real, and real gases. The volumetric and adiabatic efficiencies for semi-real and real gases differed little, but those for ideal gas differed by 18% and 25% compared with those for real gas at 2,000rpm. The volumetric efficiency changed little as the design angle of scroll (${\gamma}$) changed, but the adiabatic efficiency at ${\gamma}$ of $34^{\circ}$ was higher by 2.4% than that of $147^{\circ}$ for 2,000rpm. The volumetric and adiabatic efficiencies at scroll height of 29.8mm were higher by 1.7% and 2.8% than those of 65.8mm. The volumetric efficiency changed little as the size of discharge port changed, but the adiabatic efficiency increased a little as the size of discharge port decreased.

• Journal of the Semiconductor & Display Technology
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• v.10 no.1
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• pp.17-22
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• 2011

LEDs(Light Emitting Diodes) are becoming widely used and increasingly in demand. Quality inspection of the LEDs has become more important. Two-dimensional inspection systems are limited in inspection capability, so threedimensional(3-D) inspection systems are needed. In this paper, a cost-effective and simple 3-D measurement system of LED packages using phase measuring profilometry(PMP) is proposed. The proposed system uses a pico projector to project sinusoidal fringe patterns and to shift phases instead of piezocrystal. It was evaluated using extremely accurate gauge blocks, yielding excellent repeatability of about 12 um(3-sigma). 3-D measurements of various LED packages were performed to demonstrate the applicability and efficiency of the proposed system.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.99-99
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• 2015

본 연구에서는 금강 유역을 대상으로 토양저류함수모형기반의 개념적 강우유출모형의 장기 유출모의를 평가하였다. 연구유역인 금강 22개 계측유역을 주요 유역특성인자(면적, 경사도, SCS-CN등)을 수문학적 거리 산정방법을 활용하여 3개의 유역그룹을 선정하였다. 적용모형인 개념적 강우유출모형은 3개의 토양저류함수모형[확률분포모형(PDM: Probability Distributed Moisture), 유역습윤지수모형(CWI: Catchment Wetness Index), 수정펜맨타입모형(MP: Modified Penman type model)]과 3개의 유역추적모형[병렬2선형 저류지 유출 모형(2PAR: 2-conceptual reservoirs in parallel), 빠른 지표하 흐름을 고려한 병렬 2선형 저류지 유출모형(2PMP: 2Macro-pre Approach parallel structure), 병렬 3선형 저류지 유출모형(3PAR: 3-conceptual reservoirs in parallel)]의 조합인 9개의 모형을 사용하였으며, 2006년부터 2012년의 일자료를 바탕으로 검정(Calibration), 2001년부터 2005년의 일자료를 검증(Validation)을 Monte carlo method(Uniform Random Sampling)로 수행 후, 모형의 성능은 NSE(Nash sutcliffe Efficiency)로 평가하였다. 분석결과 유역그룹에 대한 모형성능의 편차는 작아서 유역그룹에 대한 토양저류 함수모형의 뚜렷한 상관성을 확인할 수 없었다. 이는 금강 유역을 단일 유역 그룹으로 적용할 수 있음을 제시하고 있다. 검정 검증성능 및 검정매개변수의 개수를 바탕으로 적용성 평가를 실시한 결과에서 토양저류함수모형인 확률분포모형(PDM)과 유역추적모형의 병렬2선형 저류지 유출모형(2PAR)와 빠른 지표하 흐름을 고려한 병렬2선형 저류지 유출모형(2PMP)의 조합이 금강 22개 유역에서 적용성이 우수함을 확인하였다. 향후 이 모형을 바탕으로 금강유역의 대표적인 강우유출모형을 개발하고자 한다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.714-717
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• 2017

Schwann cells and Neuronal cells were isolated from dorsal root ganglion (DRG) in embryos of rat in vitro respectively. The cultured Schwann cells and cultured neuronal cells, respectively were co-cultured in a same plate. These cells were performed accomplishment of myelination. This myelinated co-culture system was infected by Semliki forest virus and then induced demyelination processing in this myelinated co-culture. We identified myelination and demyelination processing using antibody of peripheral myelin protein 22 (PMP 22) meaning presence of myelinated neuron.

• Proceedings of the Korean Information Science Society Conference
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• 2008.06d
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• pp.19-22
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• 2008

임베디드 시스템은 MP3 Player, PMP, PDA 등 우리 생활의 일부분으로 자리 잡고 있으며, 이 외에도 로봇 시스템, 공장자동화 시스템, 군사기기 및 센서 노드 등에도 내장되어 사용 되어지고 있다. 이러한 임베디드 시스템은 앞으로도 나날이 발전을 하여 각 개인이 최소 하나 이상씩은 휴대를 할 정도로 임베디드 기기에 대한 의존도가 높아 질것이며, 이렇게 임베디드 기기에 대한 의존도가 높아질수록 더 많은 개인 정보들이 임베디드 기기에 저장이 될 것이다. 이에 따라 임베디드 기기내의 개인 정보 보호가 급격히 대두 될 것이다. 본 논문에서는 이러한 임베디드 기기내의 개인 정보 보호와 시스템 자원 보호를 위하여 사용자 인증과 접근제어기법에 대해 알아보도록 하겠다.

• Progress in Medical Physics
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• v.28 no.1
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• pp.22-26
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• 2017

We have developed an analytic software that can easily analyze the spot position and width of proton beam therapy nozzles in a periodic quality assurance. The developed software consists of an image processing method that conducts an analysis using center-of-spot geometry and a Gaussian fitting method that conducts an analysis through Gaussian fitting. By using the software, an analysis of 210 proton spots with energies 150, 190, and 230 MeV showed a deviation of approximately 3% from the mean. The software we developed to analyze proton spot positions and widths provides an accurate analysis and reduces the time for analysis.