• Food Science and Biotechnology
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• v.18 no.5
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• pp.1193-1198
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• 2009

Ethylacetate and butanol fractions of leaf extracts (OLE) showed the higher contents of total phenolic compounds than hexane and water fractions. Oleuropein contents were $4.21{\pm}0.57,\;3.92{\pm}0.43,\;0.32{\pm}0.03,\;5.76{\pm}0.32$, and $32.47{\pm}0.25mg$/100g for ethanol extract, and hexane, chloroform, ethyl acetate, and butanol fraction, respectively. Treatment of ultraviolet-B (UVB) irradiated cells with 3 OLEs prepared by using ethylacetate and butanol at concentrations 0.001, 0.005, and 0.01% respectively showed significant recovery of cell viabilities. Treatment of dexametason 1 mM reduced tumor necrotic factor (TNF)-${\alpha}$ secretion by about 40%. UVB irradiated immortalized human keratinocytes (HaCaT) cells were treated with 3 different OLEs at the same concentrations. Ethylacetate fraction showed the strongest inhibition activity with respect of reduction of the elevated (TNF)-${\alpha}$. Cytotoxicity of OLEs on the B16-F1 cells was evaluated through thiazolyl blue tetrazolium bromide (MTT) assay. Ethylacetate fraction has no cytotoxicity in the range of 0.005-0.01%. A slight cytotoxicity was observed at the concentration of 0.1% butanol fraction of OLE that caused 10% decrease in cell viability.

• Journal of the Korean Society of Food Culture
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• v.32 no.2
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• pp.135-143
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• 2017

This study evaluated the quality characteristics of semi-dried noodles prepared with different water contents (wet noodles; 32, 24, 22, 20%, dry noodles; 12%). The drying process was carried out in a drying chamber at $13{\sim}18^{\circ}C$ temperature and 75~95% humidity. The proximate composition of Korean wheat flour was as follows: water $22.1{\pm}3.64%$, protein $8.6{\pm}0.13%$, fat $1.3{\pm}0.10%$, ash $0.7{\pm}0.02%$, carbohydrates $67.3{\pm}0.10%$. As water contents decreased, both L and b values significantly decreased before cooking of noodles, whereas L, a, and b values were not significantly different after cooking of noodles. Weight, water absorption, and volume of cooked noodles significantly increased as water content decreased, whereas turbidity of soup was not significantly different. Cutting hardness before cooking of noodles significantly increased as water content decreased. Sections of noodles after cooking by SEM (scanning electron microscopy) showed roughness and fewer round starch particles as water content decreased. For overall preferences according to the sensory evaluation, noodles prepared with different water contents were not significantly different. According to the results, semidried noodles have development potential to complement the disadvantages of both wet noodles and dry noodles.

• The Journal of Pediatrics of Korean Medicine
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• v.32 no.4
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• pp.87-102
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• 2018

Objectives This study aims to investigate the effect of the Korean medicine in treating dysmenorrhea as a part of school health program (SHP) and satisfaction rate of the participated students in this program. With this study, we tried to contribute to the development of health promotion program of Korean medicine. Methods As part of the 'Korean Medicine Health Promotion Project', we conducted a dysmenorrhea program at one of many high schools in Eumseong-gun. From April to June 2018, we conducted the promotion program a total of 7 times and analyzed the questionnaire regarding satisfaction and the monthly experience of menstruation. Results The study participants' grade distribution was $2^{nd}$ grade 32, $3^{rd}$ grade 23 with a total 55 students. Mean dysmenorrhea VAS was $6.07{\pm}2.10$, and the mean number of visits to the dysmenorrhea program was $3.61{\pm}1.47$. There were no significant differences in the average number of visits between grades. Overall satisfaction was $4.06{\pm}0.97$, teacher satisfaction was $4.29{\pm}1.10$, and lecture satisfaction was $4.18{\pm}0.95$. Dysmenorrhea decreased but was not statistically significant. Conclusions Korean medicine is appropriate for the health promotion program. With cooperation and support from local schools, it will be very possible to carry out a successful business. It is also necessary to organize the program according to the viewpoint of youth and to interact with the students.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.332-332
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• 1994

식이습관을 바꾸지 않는 상태에서 4주간의 placebo 투여후 혈청 Total-C치가 240mg/dl 이상인 원발성 고콜레스테 혈증환자 25예씩 두군으로 하여 제1군은 lovastatin 20mg에서 80mg을 1일 1회 저녁에 12주간 투여하였고, 제2군은 pravastatin 5mg을 12주간 아침 저녁으로 2회 경구 투여하였다. Lovastatin과 pravastatin 12주 투여후 혈청 Total-C치는 309$\pm$46mg/d1에서 201$\pm$37mg/d1로, 281$\pm$41mg/d1에서 218$\pm$31mg/d1로, 혈청LDL-C치는 230$\pm$46mg/d1에서 125$\pm$40mg/d1로, 199$\pm$46mg/d1에서 137$\pm$37mg/d1로 각각 유의하게 감소 하였다. (p < 0.005)혈청 Apo B치는 183$\pm$32mg/d1에서 114$\pm$26mg/d1로, 164$\pm$38mg/d1에서 123$\pm$20mg/d1로, 혈청 Apo B / Apo A-1 ratio는 1.6$\pm$0.4에서 1.0$\pm$0.3으로, 1.4$\pm$0.5에서 1.0$\pm$0.3으로 각각 유의하게 감소하였다. (p < 0.005) Lovastatin 및 pravastatin 투여후 임상적으로 의미있는 중상이나 검사상 이상 소견은 관찰되지 않았다.

• Journal of Veterinary Clinics
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• v.15 no.1
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• pp.79-82
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• 1998

This study was performed to determine the changes of serum enzyme activities in rats with hepatic injury induced by the administration of AAPH. Minor behavioral change, brittleness of skin hair and decreased water and fled intake were observed in rats administered intraperitoneally with AAPH. Serum AST and ALT activities pre-treatment were $65{\pm} 13.8 and 32{\pm}$ 12.6 IU/L, respectively and increased sharply from 2 hours of administration and reached $1248{\pm} 77.6 and 946{\pm}$ 45.6 IU/L, respectively at 48 hours of administration. Serum ALP and $\gamma -GTP activities pretreatment were 221 {\pm} 75.6 and 2.2{\pm}$ 0.35 IU/L respectively and increased sharply from 8 hours of administration and reached $767{\pm} 44.9 IU/L and 8.0{\pm} 1.23 IU/L,$ respectively at 48 hours of administration.

• Journal of Chest Surgery
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• v.31 no.9
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• pp.827-836
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• 1998

Background: Effective cardiopulmonary resuscitation (CPR) should provide acceptable hemodynamics for the vital organs during cardiac arrest and early restoration of spontaneous circulation that guarantees long-term, neurologically intact survival. CPR using heart-lung bypass has been suggested as an option for that use. This study was designed to determine the effectiveness of standard CPR techniques, closed-vs. open-chest CPR, which could be used in the future study verifying the role of heart-lung bypass CPR. Material and Method: By using adult mongrel dogs, closed-chest CPR (CCCPR, n=4) and open-chest CPR (OCCPR, n=5) were compared with respects to hemodynamics, restoration of spontaneous circulation(ROSC), and survival. Ventricular fibrillation-cardiac arrest (VF-CA) was induced by electrical shock in all animals. After 4 minutes of cardiac arrest, basic life support (BLS) was applied for 15 minutes and followed by advanced life support (ALS). ALS was maintained until achi ving ROSC but not longer than 30 minutes regardless of the recovery. Resuscitation procedures in either group were standardized by adopting the protocol of American Heart Association. Result: Prearrest baseline hemodynamic data was not different between two groups. During resuscitation, substantially higher systolic pressure was maintained in OCCPR group than in CCCPR group (45$\pm$15 vs. 33$\pm$11 mmHg during BLS, 83$\pm$36 vs. 44$\pm$15 mmHg during ALS; p=NS). Mean pulmonary arterial pressure went up to the level of mean systemic arterial pressures in CCCPR group and to half of that in OCCPR group, and had kept higher in CCCPR group throughout CPR (32$\pm$10 vs. 22$\pm$4 mmHg during BLS and 32$\pm$15 vs. 24$\pm$10 mmHg during ALS; p=NS). ROSC was obtained in 4 of 5 dogs receiving open-chest CPR and 2 of 4 closed-chest CPR. Prolonged survival was noted in all dogs in OCCPR group (6 to 1440 hours) but not in CCPR group (p<.05). Conclusion: These findings indicate that open-chest CPR can be more effective t maintain hemodynamics during cardiac arrest and to obtain restoration of spontaneous circulation and survival. Further experiment will be designed to compare heart-lung bypass CPR with open-chest CPR.

• Journal of Radiation Protection and Research
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• v.21 no.2
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• pp.107-115
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• 1996

An electrolytic enrichment technique was used to measure low levels of tritium in seawater around the Korean peninsula. Tritium concentrations were determined for surface seawater samples collected from the East Sea, the South Sea, and the Yellow Sea. The tritium concentrations in surface seawater samples from the study area ranged from $0.12 BqL^{-1}\;to\;1.50BqL^{-1}$ with a mean value of $0.60{\pm}0.35 BqL^{-1}$. The means of the tritium concentration were $0.54{\pm}0.30 BqL^{-1}$ for the East Sea, $0.48{\pm}0.35 BqL^{-1}$ for the South Sea, and $0.77{\pm}0.32 BqL^{-1}$ for the Yellow Sea. The tritium concentrations in the sea areas did not show much difference no matter where the samples were taken. Due to the limited number and distribution of sampling points, no systematic change in tritium levels with latitude was observed. Measured tritium levels were similar to those observed in other data collected near Japan, but higher than mid-Pacific Ocean measurements.

• Archives of Plastic Surgery
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• v.43 no.1
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• pp.32-37
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• 2016

Background We conducted this study to analyze the values of the key cephalometric angular measurements of the mandible using 3-dimensional (3D) computed tomography scans. Methods In the 106 enrolled patients, a 3D cephalometric analysis was performed to measure the angular variables of the mandible. These values were compared between the two sides and between the two sexes. Results The frontal measurements revealed that the mandibular body curve angle was larger on the left (Lt) side (right [Rt], $141.24{\pm}7.54$; Lt, $142.68{\pm}6.94$; P=0.002) and the gonial angle was larger on the right side (Rt, $134.37{\pm}8.44$; Lt, $131.54{\pm}7.14$; P<0.001). The sagittal measurements showed that the gonial angle was larger on the right side (Rt, $134.37{\pm}8.44$; Lt, $131.54{\pm}7.14$; P>0.05). Further, the transverse measurements revealed that the mandibular body curve angle was larger on the right side (Rt, $140.28{\pm}7.05$; Lt, $137.56{\pm}6.23$; P<0.001). Conclusions These results provide an average of the mandibular angular measurements for the Korean population, establishing a standard for determining surgical patient groups and outcome evaluations in the field of mandible contour surgery.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.37 no.5
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• pp.385-392
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• 2004

Gonadal development, gametogenesis, reproductive cycle, gonad index, and flesh weight rate of the murex shell (Ocenebra japonica) collected from the rocky intertidal zone of Buan-gun, Jeollabuk-do, Korea were investigated by means of histological method from January to December 2002. O. japonica had separate sexes, and was oviparous. The gonad was widely situated on the surface of the digestive gland located in the rear of the spiral flesh part in the shell. The male penis was located near the two tentacles. The ovary was composed of a number of oogenic follicles, and the testis was composed of several spermatogenic tubules. The size of ripe oocyte was approximately $140{\mu}m$ in diameter. The gonad index (GI) began to increase in March $(33.24{\pm}2.33)$ and reached the maximum in June $(47.77{\pm}1.90)$ Thereafter, the values decreased from July $(45.12{\pm}3.60)$ to October $(19.32{\pm}2.91)$. The flesh weight rate (FWR) began to increase in January $(25.93{\pm}1.32)$ and reached the maxium in May $(31.78{\pm}1.09)$ Thereafter, the values decreased from June $(31.50{\pm}0.66)$ to October $(24.09{\pm}1.60)$. The reproductive cycle could be classified into five successive stages: early active (October to April), late active (January to June), ripe (May to September), spawning (July to September) and recovery (September to February). The reproductive cycle was closely related to the seawater temperature.

• Journal of Animal Science and Technology
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• v.55 no.5
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• pp.405-416
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• 2013

This aim of this study was to estimate the most reasonable slaughter month for Hanwoo steers according to carcass traits. Carcass trait data on Hanwoo steers (17,249 head) were collected from October 2008 to September 2011. To measure the regression coefficients, Hanwoo steers were divided into two groups according to slaughter age: early (25 to 31 months) and late (32 to 38 months) groups. Regression coefficients of carcass traits according to slaughter age were significantly different (p<0.001) with the exception of PPKG (estimated auction price per 1 kg of carcass weight) in the early slaughter age group and MAR (marbling score, p<0.05) and PPKG (p<0.05) in the late slaughter age group. To obtain a positive gross margin, Hanwoo should be slaughtered at around 28 months of age.