• 제목/요약/키워드: PM, Particulate Matter

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미세먼지에 의한 노화 및 노화 관련 질병에 대한 최근 연구 동향 (Recent Understanding in Particular Matter-Mediated Aging and Age-Related Diseases)

  • 방은진;최영현
    • 생명과학회지
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    • 제34권1호
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    • pp.68-77
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    • 2024
  • 다양한 원인에 의하여 발생하는 미세먼지(particulate matter, PM)는 강력한 환경 오염 물질로 대두되고 있다. PM은 서로 다른 구성과 크기의 고체 입자와 액체 방울로 구성되며, 유해 화학 성분에는 원소 및 유기 탄소, 유기 화합물, 생물학적 화합물 및 금속이 포함된다. 급성 및 만성 PM 노출 시 생체 내 생리학적 시스템에 의하여 유입되고 축적되어 세포내 소포체 스트레스, 미토콘드리아 기능 장애, 산화 스트레스, 염증, 지질 축적 및 세포 주기 정지와 함께 세포 구조 변화를 촉진한다. 궁극적으로 이러한 세포 반응은 노화의 주요 특성을 발달시키는 원인으로 작용하며, 세포 노화와 관련된 자가포식 플럭스 및 리소좀 기능 장애를 향상시킨다. 선행 연구에서 PM과 사망률 증가 또는 수명 감소 사이의 긍정적인 연관성을 강조했지만, 노화에 대한 PM의 직접적인 증거는 여전히 제한적이다. 이 총설에서는 관찰 연구뿐만 아니라 노화 진행 및 연령 관련 질병 발병에 대한 PM의 시험관 내 및 생체 내 증거를 평가하였다. 이러한 평가는 소포체 스트레스, 미토콘드리아 기능 장애, 산화 스트레스, 염증, 지방 축적, 자가포식을 포함하여 PM 노출과 노화 사이의 연관성을 강화하는 연령 관련 세포 변화를 기반으로 한다. 이러한 자료는 PM에 따른 기본적인 세포 반응의 이해를 토대로 PM으로 인한 노화에 대한 새로운 치료법 개발에 기여할 수 있을 것이다.

Size Distribution and Source Identification of Airborne Particulate Matter and Metallic Elements in a Typical Industrial City

  • Ny, Mai Tra;Lee, Byeong-Kyu
    • Asian Journal of Atmospheric Environment
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    • 제4권1호
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    • pp.9-19
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    • 2010
  • The size distribution of airborne particulate matter (PM) and the concentrations of associated metallic elements were investigated in a busy urban region of a typical Korean industrial city. The PM concentrations measured during the spring, except for those in the size range of 1.1 to 2.1 ${\mu}m$, were slightly higher than the PM concentrations in the summer. Coarse particles contributed greatly to the variation in PM concentrations in the spring, while fine and submicron particles contributed largely to the variation in PM concentrations in the summer. The difference in size modes of the PM concentrations between spring and summer may be explained by the Asian dust effect and its accompanying wind direction and speed. Extremely high enrichment factors (EFs) values (6,971 to 60,966) for all of the size distributions in PM were identified for cadmium (Cd). High EFs values (12 to 907) were also identified for other heavy metals including Cr, Cu, Ni, Pb, Zn and Mn. Low EF values (0.29 to 8.61) were identified for Ca, K, Mg and Na. These results support the common hypothesis that most heavy metals in ambient PM have anthropogenic sources and most light metals have crustal sources. The results of principal components analyses and cluster analyses for heavy metals indicate that the principal sources of PM and metals were emissions from non-ferrous metal smelters, oil combustion, incinerators, vehicular traffic and road dust.

小型디젤機關에서 CVS-75 모드에 따른 디젤 酸化觸媒裝置의 排出가스 低減에 關한 實驗的 硏究 (An Experimental Study on Exhaust Gas Reduction of Diesel Oxidation Catalyst by CVS-75 Mode in Light Duty Diesel Engine)

  • 한영출;김종춘;오용석
    • 한국대기환경학회지
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    • 제15권4호
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    • pp.457-461
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    • 1999
  • Recently, increasing usage of diesel vehicle, many countries try to reduce the pollutant materials by emission regulation standard. Particularly, in our country, the supplement ratio of diesel vehicle is high, and air pollution by particulate matter(PM) is very serious. So, in theoretical study wer analyzed the formation principle of gaseous emission and PM, the characteristics of CVS-75 mode. In experimental study, we tested exhaust gas reduction of emission and PM, the characteristics of CVS-75 mode. In experimental study, we tested exhaust gas reduction of disel oxidation catalyst(DOC) by CVS-75 mode in light duty diesel vehicle. In case of an automobiletest with the 2,956cc diesel engine which DOC was equipped, CVS-75 mode which is similar to driving conditions on the road was chosen as the restrictive mode of light duty diesel automobile in our country. According to the Pt, the reduction rate of exhaust emission was estimated with using 0.1% high sulfur fuel and 0.05% low sulfur fuel.

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Particle size distributions and concentrations above radiators in indoor environments: Exploratory results from Xi'an, China

  • Chen, Xi;Li, Angui
    • Environmental Engineering Research
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    • 제20권3호
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    • pp.237-245
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    • 2015
  • Particulate matter in indoor environments has caused public concerns in recent years. The objective of this research is to explore the influence of radiators on particle size distributions and concentrations. The particle size distributions as well as concentrations above radiators and in the adjacent indoor air are monitored in forty-two indoor environments in Xi'an, China. The temperatures, relative humidity and air velocities are also measured. The particle size distributions above radiators at ten locations are analyzed. The results show that the functional difference of indoor environments has little impact on the particle size distributions above radiators. Then the effects of the environmental parameters (particle concentrations in the adjacent indoor air, temperatures, relative humidities and air velocities) on particle concentrations above radiators are assessed by applying multiple linear regression analysis. Three multiple linear regression models are established to predict the concentrations of $PM_{10}$, $PM_{2.5}$ and $PM_1$ above radiators.

기기중성자방사화분석을 이용한 대전 3, 4 공단지역의 호흡성입자의 특성 (Characteristics of Respirable Particulate Matter from the Third and Fourth Industrial Complex Area of Daejeon City Using Instrumental Neutron Activation Analysis)

  • 임종명;이진홍
    • 환경영향평가
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    • 제15권6호
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    • pp.425-433
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    • 2006
  • Instrumental neutron activation analysis was used to measure the concentrations of 27 elements associated with respirable particulate matter (PM10) that were collected from the Third and Fourth Industrial Complex Area of Daejeon City. The distribution patterns of elements were clearly distinguished with their concentrations varying across more than four orders of magnitude. The mean for Al were recorded to be the highest value of 1,527 $ng/m^3$, while that for In showed the lowest value of 0.1 $ng/m^3$. If compared in terms of enrichment factors, it was found that certain elements (e.g., As, Br, Cl, Cr, I, In, Sb, Se, and Zn) are enriched in PM10 samples of the study site. The results of factor analysis indicated six factors with statistical significance, which may exert dominant controls on regulating the elemental concentration levels in the study area.

A meta-analysis of exposure to particulate matter and adverse birth outcomes

  • Lamichhane, Dirga Kumar;Leem, Jong-Han;Lee, Ji-Young;Kim, Hwan-Cheol
    • Environmental Analysis Health and Toxicology
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    • 제30권
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    • pp.11.1-11.19
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    • 2015
  • Objectives The objective of this study was to conduct a systematic review to provide summarized evidence on the association between maternal exposure to particulate air pollution and birth weight (BW) and preterm birth (PTB) after taking into consideration the potential confounding effect of maternal smoking. Methods We systematically searched all published cohort and case-control studies examining BW and PTB association with particulate matter (PM, less than or equal to $2.5{\mu}m$ and $10.0{\mu}m$ in diameter, $PM_{2.5}$ and $PM_{10}$, respectively) from PubMed and Web of Science, from January 1980 to April 2015. We extracted coefficients for continuous BW and odds ratio (OR) for PTB from each individual study, and meta-analysis was used to combine the coefficient and OR of individual studies. The methodological quality of individual study was assessed using a standard protocol proposed by Downs and Black. Forty-four studies met the inclusion criteria. Results In random effects meta-analyses, BW as a continuous outcome was negatively associated with $10{\mu}g/m^3$ increase in $PM_{10}$ (-10.31 g; 95% confidence interval [CI], -13.57 to -3.13 g; I-squared=0%, p=0.947) and $PM_{2.5}$ (-22.17 g; 95% CI, -37.93 to -6.41 g; Isquared=92.3%, p<0.001) exposure during entire pregnancy, adjusted for maternal smoking. A significantly increased risk of PTB per $10{\mu}g/m^3$ increase in $PM_{10}$ (OR, 1.23; 95% CI, 1.04 to 1.41; I-squared=0%, p=0.977) and $PM_{2.5}$ (OR, 1.14; 95% CI, 1.06 to 1.22; I-squared=92.5%, p<0.001) exposure during entire pregnancy was observed. Effect size of change in BW per $10{\mu}g/m^3$ increase in PM tended to report stronger associations after adjustment for maternal smoking. Conclusions While this systematic review supports an adverse impact of maternal exposure to particulate air pollution on birth outcomes, variation in effects by exposure period and sources of heterogeneity between studies should be further explored.

바이오디젤의 미세입자 배출특성 (Nano Particle Emission Charataristics of Biodiesel)

  • 송호영;이민호;김재권;정충섭
    • 한국신재생에너지학회:학술대회논문집
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    • 한국신재생에너지학회 2010년도 추계학술대회 초록집
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    • pp.199.2-199.2
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    • 2010
  • Biodiesels are well-known as alternative fuels. also we know that biodiesels increase NOx and reduce PM(Particulate Matter) by previous many studies. But PM in most these studies was considered about the mass. In this study, We have performed experimental test for PM and exhaust emission by mixed ratio of biodiesel in heavy duty diesel engine. PM was investigated by The nano particle number and the mass. The mass of PM was evaluated by using the standard gravimetric method, The number of PM was evaluated by using the EEPS(Engine Exhaust Particle Sizer), on the ESC(European Steady Cycle) mode. Sampled gas through dilutor was directly extracted from tail pipe and EEPS measured diluted exhaust gas. Biodiesel is made up of used cooking oil. Diesel as base fuel was sold on market and contains 2% biodiesel. The mass of PM was reduced 10% and the nano particle number was increased 5%. The particle number less than 40nm was increased, but the particle number more than 40nm is decreased.

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입자상물질의 광학밀도 및 농도측정에 적용된 저가형 광학 부품의 성능평가 (Performance Evaluation of Low-cost Optical Components used for Measuring the Optical Density and Concentration of Particulate Matter(PM))

  • 백영조;홍터기;황철홍;박설현
    • 한국안전학회지
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    • 제31권5호
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    • pp.1-6
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    • 2016
  • The performance of a set of low-cost optical components used for measuring the optical density of PM particles was evaluated in the present study. To this end, the set of low-cost optical components was replaced with that of general optical components used to measure the PM optical density under identical experimental conditions. The optical densities measured from the set of general optical components were then compared to those obtained from the set of low-cost optical components. While the optical density is measured, another key parameter, the dimensionless extinction constant of PM particles (which is needed to optically measure the PM concentration) was also determined in the present study. The experimental results indicate that the optical density and PM concentration measurements performed by low-cost optical components are feasible, producing trackable variations in the OD and concentrations compared to values obtained from the set of general optical components.