• Title/Summary/Keyword: PI4

Search Result 2,332, Processing Time 0.031 seconds

${\pi}G{\alpha}$-LOCALLY CLOSED SETS AND ${\pi}G{\alpha}$-LOCALLY CONTINUOUS FUNCTIONS

  • Rani, I. Arockia;Balachandran, K.;Janaki, C.
    • East Asian mathematical journal
    • /
    • v.24 no.4
    • /
    • pp.317-328
    • /
    • 2008
  • In this paper we introduce ${\pi}G{\alpha}$-LC sets, ${\pi}G{\alpha}-LC^*$ sets and ${\pi}G{\alpha}-LC^{**}$ sets and different notions of generalizations of continuous functions in topological space and discuss some of their properties. Further we prove pasting lemma for ${\pi}G{\alpha}-LC^{**}$ continuous functions and ${\pi}G{\alpha}-LC^{**}$ irresolute functions.

  • PDF

NEW SERIES IDENTITIES FOR ${\frac{1}{\Pi}}$

  • Awad, Mohammed M.;Mohammed, Asmaa O.;Rakha, Medhat A.;Rathie, Arjun K.
    • Communications of the Korean Mathematical Society
    • /
    • v.32 no.4
    • /
    • pp.865-874
    • /
    • 2017
  • In the theory of hypergeometric and generalized hypergeometric series, classical summation theorems have been found interesting applications in obtaining various series identities for ${\Pi}$, ${\Pi}^2$ and ${\frac{1}{\Pi}}$. The aim of this research paper is to provide twelve general formulas for ${\frac{1}{\Pi}}$. On specializing the parameters, a large number of very interesting series identities for ${\frac{1}{\Pi}}$ not previously appeared in the literature have been obtained. Also, several other results for multiples of ${\Pi}$, ${\Pi}^2$, ${\frac{1}{{\Pi}^2}}$, ${\frac{1}{{\Pi}^3}}$ and ${\frac{1}{\sqrt{\Pi}}}$ have been obtained. The results are established with the help of the extensions of classical Gauss's summation theorem available in the literature.

Facilitation of Glucose Uptake by Lupeol through the Activation of the PI3K/AKT and AMPK Dependent Pathways in 3T3-L1 Adipocytes (3T3-L1 지방세포에서 PI3K/AKT 및 AMPK 경로의 활성화를 통한 루페올의 포도당 흡수촉진 효과)

  • Lee, Hyun-Ah;Han, Ji-Sook
    • Journal of Life Science
    • /
    • v.32 no.2
    • /
    • pp.86-93
    • /
    • 2022
  • Lupeol is a type of pentacyclic triterpene and has been reported to have pharmacological activities against various diseases; however, the effect of lupeol on glucose absorption has not been elucidated yet. This study aimed to investigate the effect of lupeol on glucose uptake in 3T3-L1 adipocytes. Lupeol significantly facilitated glucose uptake by translocating glucose transporter type 4 (GLUT4) to the plasma membrane of the 3T3-L1 adipocytes, which was related to activation of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) and 5 'adenosine monophosphate-activated protein kinase (AMPK) pathways. In the PI3K/AKT pathway, lupeol stimulates the phosphorylation of insulin receptor substrate 1 (IRS-1), which activates PI3K. Its activation by lupeol promotes the phosphorylation of AKT, but not the atypical protein kinase C isoforms ζ and λ. Lupeol also promoted the phosphorylation of AMPK. The activation of AMPK increased the expressions of the plasma membrane GLUT4 and the intracellular glucose uptake. The increase in the glucose uptake by lupeol was suppressed by wortmannin (PI3K inhibitor) and compound C (AMPK inhibitor) in the 3T3-L1 adipocytes. The results indicate that lupeol can facilitate glucose uptake by increasing insulin sensitivity through the stimulation of the expression of plasma membrane glucose transporter type 4 via the PI3K/AKT and AMPK pathways in the 3T3-L1 adipocytes.

Prostate Imaging-Reporting and Data System: Comparison of the Diagnostic Performance between Version 2.0 and 2.1 for Prostatic Peripheral Zone

  • Hyun Soo Kim;Ghee Young Kwon;Min Je Kim;Sung Yoon Park
    • Korean Journal of Radiology
    • /
    • v.22 no.7
    • /
    • pp.1100-1109
    • /
    • 2021
  • Objective: To compare the diagnostic performance between Prostate Imaging-Reporting and Data System version 2.0 (PI-RADSv2.0) and version 2.1 (PI-RADSv2.1) for clinically significant prostate cancer (csPCa) in the peripheral zone (PZ). Materials and Methods: This retrospective study included 317 patients who underwent multiparametric magnetic resonance imaging and targeted biopsy for PZ lesions. Definition of csPCa was International Society of Urologic Pathology grade ≥ 2 cancer. Area under the curve (AUC), sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy for csPCa were analyzed by two readers. The cancer detection rate (CDR) for csPCa was investigated according to the PI-RADS categories. Results: AUC of PI-RADSv2.1 (0.856 and 0.858 for reader 1 and 2 respectively) was higher than that of PI-RADSv2.0 (0.795 and 0.747 for reader 1 and 2 respectively) (both p < 0.001). Sensitivity, specificity, PPV, NPV, and accuracy for PI-RADSv2.0 vs. PI-RADSv2.1 were 93.2% vs. 88.3% (p = 0.023), 52.8% vs. 76.6% (p < 0.001), 48.7% vs. 64.5% (p < 0.001), 94.2% vs. 93.2% (p = 0.504), and 65.9% vs. 80.4% (p < 0.001) for reader 1, and 96.1% vs. 92.2% (p = 0.046), 34.1% vs. 72.4% (p < 0.001), 41.3% vs. 61.7% (p < 0.001), 94.8% vs. 95.1% (p = 0.869), and 54.3% vs. 78.9% (p < 0.001) for reader 2, respectively. CDRs of PI-RADS categories 1-2, 3, 4, and 5 for PI-RADSv2.0 vs. PI-RADSv2.1 were 5.9% vs. 5.9%, 5.8% vs. 12.5%, 39.8% vs. 56.2%, and 88.9% vs. 88.9% for reader 1; and 4.5% vs. 4.1%, 6.1% vs. 11.1%, 32.5% vs. 53.4%, and 85.0% vs. 86.8% for reader 2, respectively. Conclusion: Our data demonstrated improved AUC, specificity, PPV, accuracy, and CDRs of category 3 or 4 of PI-RADSv2.1, but decreased sensitivity, compared with PI-RADSv2.0, for csPCa in PZ.

Development of an Alignment Method for Retarders in isoSTED Microscopy

  • Ilkyu Park;Dong-Ryoung Lee
    • Current Optics and Photonics
    • /
    • v.8 no.4
    • /
    • pp.421-426
    • /
    • 2024
  • The use of stimulated emission depletion (STED) microscopy has significantly improved resolution beyond the limits imposed by diffraction; Furthermore, STED microscopy adopts a 4Pi-geometry to achieve an isotropic improvement in resolution. In isoSTED microscopy, a polarizing beam splitter and retarders are used in a 4Pi cavity to split beams of identical power, generating constructive and destructive interference for lateral and axial resolution improvements, respectively. The precise alignment of the retarders is crucial for optimizing the performance of isoSTED microscopy, because this orientation affects the quality of the depletion focus, necessitating zero intensity at the center. Incomplete destructive interference can lead to unwanted fluorescence inhibition, resulting in degraded resolution and contrast. However, measuring the intensity and polarization state in each optical path of the 4Pi cavity is complex and requires additional devices such as a power meter. Here, we propose a simple and accurate alignment method for the 4Pi cavity in isoSTED microscopy. Our approach demonstrates the equal allocation of power between upper and lower beam paths and achieves complete destructive interference using a polarizing beam displacer and a single CCD camera positioned outside the 4Pi cavity.

Wide viewing angle and fast response time using novel vertical-alignment - 1/4 ${\pi}$ cell mode

  • Lee, Jeong-Ho;Seo, Dae-Shik;Kim, Hyang-Yul
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 2000.01a
    • /
    • pp.9-10
    • /
    • 2000
  • The wide viewing angle and fast response time characteristics of negative dielectric anisotropy nematic liquid crystal (NLC) using a novel vertical-alignment (VA) - 1/4 ${\pi}$ cell mode on a homeotropic alignment layer were investigated. Good voltage-transmittance curves and low driving voltage using the novel VA - 1/4 ${\pi}$ cell mode without a negative compensation film were obtained. The iso-viewing angle characteristics of NLC using the novel VA - 1/4 ${\pi}$ cell mode without a negative compensation film can be achieved. The fast response time of 24.4 ms in NLC was successfully measured. The iso-viewing angle, fast response time, and low driving voltage characteristics using the novel VA - 1/4 ${\pi}$ cell mode can be achieved.

  • PDF

Synthesis and Photoalignment of Soluble Polyimides with Styrylpyridine Side Groups (스티릴피리딘 곁사슬기를 가지는 용해성 폴리이미드의 합성과 광배향)

  • Kim, Jin-Woo;Kim, Min-Woo;Ahn, Deuk-Kyoon;Kim, Woo-Sik
    • Polymer(Korea)
    • /
    • v.33 no.3
    • /
    • pp.207-212
    • /
    • 2009
  • The precursor polyimide of the photoreactive polyimides(PI-SP6 and PI-SP12) was prepared from a derivative of 2, 2, 2-trifluoroethane dianhydride and 3,3'-dihydroxy-4,4'-diaminobiphenyl. PI-SP6 and PI-SP12 were then prepared by the polymer reactions of the precursor polyimide with photoreactive 2-styrylpyridine alkylene (hexylene and dodecylene) derivatives, respectively. The photoreactive polymers were soluble in organic solvents. The polymers showed the initial decomposition temperatures around $350^{\circ}C$. The glass transition temperatures of PI-SP6 and PI-SP12 were found to be $130^{\circ}C$ and $85^{\circ}C$, respectively. This result means that the latter polymer is more flexible than the former polymer. Their transmittance in the film state was 90% at $250^{\circ}C$, which indicates that the photosensitive polyimides with thermal stability have high optical transparency even at the high temperature. The respective dichroic ratios of PI-SP6 and PI-SP12 were found to be 0.01 and 0.03 at an exposure energy of $1.5\;J/cm^2$. This result suggests that the latter polymer with larger flexibility compared to the former polymer is more effective for the photoalignment.

Colorless and Transparent Polyimide Films from Poly(amic acid)s with Cross-linkable Anhydride End (가교 반응이 가능한 말단 무수물을 이용한 무색투명한 폴리이미드 필름)

  • Min, Ung-Ki;Chang, Jin-Hae
    • Polymer(Korea)
    • /
    • v.34 no.6
    • /
    • pp.495-500
    • /
    • 2010
  • Crosslinked PI films were synthesized from 4,4'-(hexafluoro isopropylidene)diphthalic anhydride (6FDA) and bis[4-(3-aminophenoxy) phenyl] sulfone(BAPS) with various ratios of the reactive monomer cis-4-cyclohexene-1,2-dicarboxylic anhydride(CDBA). We prepared crosslinked poly(amic acid) (PAA) using a 0.1 wt% Grubbs catalyst as a crosslinking agent. The crosslinked PAA was heat-treated at different temperatures to give PI films. The thermo-mechanical properties and optical transparency of the PI films were investigated. The thermal properties of the PI films were examined using Fourier transform infrared (FTIR) spectroscopy, differential scanning calorimetry(DSC), thermogravimetric analysis(TGA), thermo-mechanical analysis(TMA), and universal tensile machine(UTM), and their optical transparencies were investigated using UV-vis. spectrophotometry. The thermomechanical properties of the PI films improved with increasing CDBA content. However, the optical transparency of the PI films decreased slightly with increasing CDBA content.

Studies on Resistance to anthracnose (Colletrichum dematium) in Pepper (고추의 탄저병(炭疽病) 저항성(抵抗性)에 관(關)한 연구(硏究))

  • Park, Hyoun Kyu;Kim, Byung Soo;Lee, Woo Sung
    • Current Research on Agriculture and Life Sciences
    • /
    • v.4
    • /
    • pp.7-11
    • /
    • 1986
  • Nine Korean local cultivars and 34 PI lines of pepper were tested for resistance to anthracnose (Colletotrichum dematium). Red ripe fruits were harvested, punctured and inoculated by spraying and dropping a conidial suspension of Colletotrichum dematium. Resistance was evaluated by measuring the diameter of ripe rot lesions developed on and around the puncture. The results obtained are as follows : 1. PI 201232, PI 224451, PI 257044, PI 257119, PI 257099, PI 224433, PI 244668, PI 257102, PI 173877, Namji, Cheongryong, and Seodong were the least diseased and considered to be resistant. 2. PI 241670, PI 244670, and PI 224423 were the most diseased and considered to be susceptible. 3. Others were in between the two extremes and considered to be intermediate.

  • PDF

CHARACTERISTICS OF THE FLOW AND HEAT TRANSFER AROUND A WAVY CYLINDER (삼차원 원형주상체의 축방향 직경변화가 열.유동장에 미치는 영향)

  • Lee, Chang-Yeol;Seo, Jang-Hoon;Yoon, Hyun-Sik;Chun, Ho-Hwan
    • 한국전산유체공학회:학술대회논문집
    • /
    • 2008.03a
    • /
    • pp.131-136
    • /
    • 2008
  • Three-dimensional characteristics of fluid flow and heat transfer around a wavy circular cylinder having sinusoidal variation in cross sectional area along the spanwise direction are numerically investigated using the immersed boundary method. The three different wavelengths of ${\pi}/4$, ${\pi}/3$ and ${\pi}/2$ and at the fixed wavy amplitude of 0.1 have been considered to investigate the effects of waviness on especially the forced convection heat transfer around a wavy cylinder when the Reynolds and Prandtl numbers are 300 and 0.71, respectively. The present computational results for a wavy cylinder are compared with those for a smooth cylinder. The time- and total surface-averaged Nusselt number for a wavy cylinder with is larger than that for a smooth cylinder, whereas that with ${\lambda}={\pi}/4$ and ${\pi}/3$ is smaller than that for a smooth cylinder. However, because the surface area exposed to heat transfer for a wavy cylinder is larger than that for a smooth cylinder, the total heat transfer rate for a wavy cylinder with different wavelengths of ${\lambda}={\pi}/4$, ${\pi}/3$ and ${\pi}/2$ is larger than that for a smooth cylinder.

  • PDF