• Title/Summary/Keyword: PFS

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The Preliminary Study for Pain Measurements of Headache Patients used by Pain Face Scale (통증 표정 척도를 이용한 두통환자의 통증평가를 위한 초보적 연구)

  • Kim, Kyeong-Ok;Choi, Geum-Ae;Kim, Woo-Chul;Kim, Kyeong-Su
    • Journal of Oriental Neuropsychiatry
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    • v.21 no.3
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    • pp.65-75
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    • 2010
  • Objectives : The aim of this study is to validate the correlation between Pain Face Scale(PFS) and Numerical Rating Scale(NRS), and to find out the methods to assess headache by PFS. Methods : The study participants included 28 headache patients. All patients answered questionnair, which include PFS, NRS, and other questions for measurements headache. It is analyzed by frequency, correlation with spss windows 14.0. Results : 1. PFS include the strength of headache, and feelings. 2. PFS express strength of headache more than NRS. 3. There was no significant relationship between aspect and regions of headache. Conclusions : Therefore PFS is objective measurement scale of headache.

Social Welfare Analysis of Policy-based Finance with Support for Corporate Loan Interest

  • NAM, CHANGWOO
    • KDI Journal of Economic Policy
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    • v.43 no.4
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    • pp.45-67
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    • 2021
  • We analyze the social welfare effect when a policy-based financial system (PFS) enters a decentralized financial market. Particularly, the PFS in this case supports the interest spread for corporate loans held by firms with heterogeneous bankruptcy decisions under an imperfect information structure. Although support for capital costs through the PFS expands the economy consistently, the optimal level of PFS out of the corporate loan market is estimated to be 8.6% by a simulation model considering social welfare adjusted by the disutility of labor. This result is much lower than the recent level of PFS in the Korean financial sector.

Optimized Image-Based Surrogate Endpoints in Targeted Therapies for Glioblastoma: A Systematic Review and Meta-Analysis of Phase III Randomized Controlled Trials

  • Chong Hyun Suh;Ho Sung Kim;Seung Chai Jung;Choong Gon Choi;Sang Joon Kim;Kyung Won Kim
    • Korean Journal of Radiology
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    • v.21 no.4
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    • pp.471-482
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    • 2020
  • Objective: We aimed to determine the optimized image-based surrogate endpoints (IBSEs) in targeted therapies for glioblastoma through a systematic review and meta-analysis of phase III randomized controlled trials (RCTs). Materials and Methods: A systematic search of OVID-MEDLINE and EMBASE for phase III RCTs on glioblastoma was performed in December 2017. Data on overall survival (OS) and IBSEs, including progression-free survival (PFS), 6-month PFS (6moPFS), 12-month PFS (12moPFS), median PFS, and objective response rate (ORR) were extracted. Weighted linear regression analysis for the hazard ratio for OS and the hazard ratios or odds ratios for IBSEs was performed. The associations between IBSEs and OS were evaluated. Subgroup analyses according to disease stage (newly diagnosed glioblastoma versus recurrent glioblastoma), types of test treatment, and types of response assessment criteria were performed. Results: Twenty-three phase III RCTs published between 2000 and 2017, including 8387 patients, met the inclusion criteria. OS showed strong correlations with PFS (standardized β coefficient [R] = 0.719), 6moPFS (R = 0.647), and 12moPFS (R = 0.638). OS showed no correlations with median PFS and ORR. In subgroup analysis according to types of therapies, PFS showed the highest correlations with OS in targeted therapies for cell cycle pathways (R = 0.913) and growth factor receptors and their downstream pathways (R = 0.962). 12moPFS showed the highest correlation with OS in antiangiogenic therapy (R = 0.821). The response assessment in neuro-oncology criteria provided higher correlation coefficients between OS and IBSEs than the Macdonald criteria. Conclusion: Overall, PFS is an optimized IBSE in targeted therapies for glioblastoma; however, 12moPFS is optimal in antiangiogenic therapy.

Perception and Satisfaction of Free Foodservice in Male Middle School Students in Chungnam (충남 일부지역 남자 중학생의 무상급식에 대한 인식 및 만족도)

  • Kim, Yu-Rin;Kim, Eun-Jin;Choi, Mi-Kyeong
    • Journal of the Korean Dietetic Association
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    • v.20 no.2
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    • pp.87-98
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    • 2014
  • The purpose of this research was to investigate perception, necessity, and satisfaction of a free foodservice in male middle school students. This study was conducted at male middle schools with paid foodservice (PFS group, 250 students) and with free foodservice (FFS group, 250 students) in Chungnam. Average age of students in the PFS group was 13.1 while that of FFS students was 12.8 years. Exactly 88% of PFS students and 94% of FFS students responded that school foodservice is necessary, which was a significant difference (P<0.05). As the reason for participating in foodservice, about 32% of the PFS students answered the school's request while 33.6% of FFS students answered nutrition, showing a significant difference (P<0.001). Exactly 72.8% of PFS and 96.4% of FFS knew about FFS (P<0.001). More PFS students (86.4%) than FFS students (66%) answered they would not participate in foodservice if the FFS would be introduced and the quality of meal service would deteriorate. After initiation to FFS, there were significant differences in assessment of foodservice: 77.6% of PFS students answered expected that the quality of foodservice would degrade, whereas 74.4% of FFS students answered that quality would not degrade (P<0.001). Satisfaction of foodservice was 2.3 points for FFS students, which was significantly lower than the 2.5 points for PFS students (P<0.001). To sum up assessment of foodservice was positive, whereas satisfaction was not significantly different between PFS and FFS. Based on this research, households, schools, and governments should promote FFS in order to diminish financial pressure for students.

Influence of MWCNTs on Fracture Toughness of MWCNTs/Nickel-Pitch Fiber/Epoxy Composites

  • Yim, Yoon-Ji;Park, Soo-Jin
    • Composites Research
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    • v.28 no.6
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    • pp.361-365
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    • 2015
  • The influence of MWCNTs on fracture toughness properties of MWCNTs/Nickel-Pitch Fibers/epoxy composites (MWCNTs/Ni-PFs/epoxy) was investigated according to MWCNTs content. Nickel-Pitch-based carbon fibers (Ni-PFs) were prepared by electroless nickel-plating. The surface properties of Ni-PFs were determined by scanning electron microscopy (SEM) and X-ray photoelectron spectrometry (XPS). The fracture toughness of MWCNTs/Ni-PFs/epoxy was assessed by critical stress intensity factor ($K_{IC}$) and critical strain energy release rate ($G_{IC}$). From the results, it was found that the fracture toughness properties of MWCNTs/Ni-PFs/epoxy were enhanced with increasing MWCNTs content, whereas the value decreased above 5 wt.%. MWCNTs content. This was probably considered that the MWCNTs entangled with each other in epoxy due to an excess of MWCNTs.

Trick or Treat? Equity Concerns in the Preliminary Feasibility Study of the Republic of Korea

  • LEE, JONGYEARN
    • KDI Journal of Economic Policy
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    • v.42 no.4
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    • pp.91-116
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    • 2020
  • As a project appraisal tool, the preliminary feasibility study (PFS) has contributed to enhancing the efficiency of public investment decision-making in the Republic of Korea over the last two decades. To overcome the limitations of the efficiency-oriented cost-benefit analysis, the PFS accommodates equity concerns among regions, namely balanced regional development (BRD) analysis. This study attempts to gauge the contributions of BRD analysis to PFS results. Specifically, it addresses how effectively policy efforts to promote decision-making have been implemented in the PFS stage while also considering the balance between equity and efficiency in terms of the trade-off between them, the degree to which they influence the results, and whether the consideration of equity is in fact actually reflected in seriously underdeveloped regions as intended. The study finds that the PFS results over the last two decades have been largely in line with the background and policy objectives. Based on the findings of the study, needs for institutional improvement are suggested, including enhancements in the analysis of regional economic ripple effects and taking into account the psychological factors pertaining to the evaluators in the overall judgment.

Survival outcomes after adjuvant radiotherapy for aggressive fibromatosis depend on time frame and nuclear β-catenin

  • Kim, Jae Sik;Kim, Hak Jae;Lee, Me-Yeon;Moon, Kyung Chul;Song, Seung Geun;Kim, Han-Soo;Han, Ilkyu;Kim, Il Han
    • Radiation Oncology Journal
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    • v.37 no.1
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    • pp.37-42
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    • 2019
  • Purpose: To identify prognostic factors influencing progression-free survival (PFS) of aggressive fibromatosis (AF) after postoperative radiotherapy (PORT) and assess correlations between immunohistochemistry (IHC) features of β-catenin/smooth muscle actin (SMA) and PFS. Materials and Methods: Records of 37 patients with AF treated by PORT from 1984 to 2015 were retrospectively reviewed. Fifteen patients underwent wide excision for AF and 22 patients received debulking operation. The median total dose of PORT was 59.4 Gy. IHC staining results of β-catenin and SMA were available for 11 and 12 patients, respectively. Results: The median follow-up duration was 105.9 months. Five-year PFS rate was 70.9%. Tumor size or margin status was not related to PFS in univariate analysis (p = 0.197 and p = 0.716, respectively). Multivariate analysis showed that increased interval from surgery to PORT (>5.7 weeks) was a marginal risk factor for PFS (p = 0.054). Administration of PORT at the initial diagnosis resulted in significantly improved PFS compared to deferring PORT after recurrence (p = 0.045). Patient with both risk factors of deferring PORT after recurrence and interval from surgery to PORT >5.7 weeks had significantly lower 5-year PFS than patients without risk factor (34.1% vs. 100.0%; p = 0.012). Nuclear β-catenin intensity tended to inversely correlate with 5-year PFS, although it did not reach statistical significance (62.5% at low vs. 100.0% at high; p = 0.260). SMA intensity was not related to PFS (p = 0.700). Conclusion: PORT should be performed immediately after surgery irrespective of margin status or tumor size especially in recurrent case. Nuclear β-catenin staining intensity of IHC might correlate with local recurrence.

Physicochemical Properties of Ground Pork with Safflower (Carthamus tinctorius L.) Seed during Refrigerated Storage (홍화씨가 분쇄돈육의 냉장 중 이화학적 품질에 미치는 영향)

  • Park, Kyung-Sook;Kim, Min-Ju;Park, Hyun-Suk;Choi, Young-Joon;Jung, In-Chul
    • Korean journal of food and cookery science
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    • v.28 no.4
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    • pp.399-405
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    • 2012
  • This study was carried out to investigate the effect of safflower seed powder on the physicochemical characteristics of ground pork during refrigerated storage. Three types of ground pork were evaluated: 20% pork fat added (PF, control), 10% pork fat and 10% added safflower seed powder (PFS), and 20% added safflower seed powder (SS). The pH increased during storage, but decreased after 10 days of the storage (p<0.05). The pH was lower in PFS and SS than that in PF after 10 days of storage (p<0.05). The TBARS (2-thiobarbituric acid reactive substances) values increased with longer storage period (p<0.05), and those of PF, PFS and SS were 1.186, 0.686 and 0.577 mg MA/kg, respectively, after 10 days of storage. The $L^*$ values for external color of PF and PFS decreased (p<0.05), but that of SS was not significantly different after a longer storage period. The $a^*$ values decreased (p<0.05), but the $b^*$ values were not significantly different with longer storage period. The $L^*$ values for internal color of PFS and SS decreased (p<0.05), but that of PF was not significantly different with longer storage period. The $a^*$ value of PF decreased (p<0.05), but that of SS increased with longer storage period. The $b^*$ value decreased (p<0.05), but those of PFS and SS were not significantly different with longer storage period. Water holding capacity decreased with longer storage period, and that of SS was the highest (p<0.05). Cooking loss of PFS and SS was not significantly different with longer storage period, and that of PF was the highest (p<0.05). The reduction in diameter of the samples was not significantly different with longer storage period, and that of PF was the highest (p<0.05). Hardness and chewiness of samples increased, but springiness and cohesiveness decreased with longer storage period (p<0.05). Replacing animal fat with safflower seed powder was effective and may be useful as an innovative meat product.

A New Review of the Iliotibial Tract's Function In Iliotibial Band Syndrome or Patellofemoral Syndrome (슬개대퇴골 증후군과 장경근막 증후군에 있어서 장경인대의 기능에 대한 새로운 문제점)

  • Park, Ji-Whan
    • Journal of Korean Physical Therapy Science
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    • v.3 no.3
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    • pp.87-91
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    • 1996
  • Until the up to day, we have known that a tight iliotibial tract has an influence on the patella, pulling it laterally and causing pain in patients with patellofemoral syndrome, so should be stretched as a part of physical therapy. But the iliotibial tract's function on the patella in subjects with PFS has not yet been proved and further questions need to be answered regarding the evlauation or treatment of a tight tract in patients with PFS.

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Infrared Spectroscopic Studies on the Ionization of Perfluorostearic Acid (적외선 분광법을 이용한 Perfluorostearic Acid의 이온화 연구)

  • Kim, Uk-Soo;Ha, Ki-Ryong
    • Applied Chemistry for Engineering
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    • v.19 no.1
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    • pp.111-116
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    • 2008
  • Collapsed perflurostearic acid (PFS) films were prepared on the different pH and the various metal ion ($Na^+$, $Ca^{2+}$, $La^{3+}$) containing subphase using Langmuir-Blodgett (LB) trough. The degree of ionization of collapsed PFS film formed from floating monolayer has been determined by Fourier transform infrared (FTIR) spectroscopy. The intensity of C = O of -COOH peaks of collapsed PFS decreased with increasing pH of subphase. The order of ionization of collapsed PFS on the subphase of the same pH was $La^{3+}$ > $Ca^{2+}$ > $Na^+$. The degree of ionization of collapsed PFS on the Deionized (D.I.) water subphase is above 50% even at subpahse pH 3, which is much higher degree of ionization than that of stearic acid.