• Title/Summary/Keyword: PEG2

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Separation of Antioxidants and Glucose from Grape Skin Extract Using Polyethylene Glycol and Sodium Citrate (폴리에틸렌글리콜과 구연산 나트륨을 이용하여 포도껍질 추출물에서 항산화물질과 포도당 분리)

  • Eun Min Shin;Yeong Eun Joo;Su Min Jung;Jaechan Suh;Chang-Joon Kim
    • Clean Technology
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    • v.29 no.2
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    • pp.109-117
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    • 2023
  • The purpose of this study is to develop a method for separating antioxidants and sugars from grape skin extract. The extract was first mixed with a variety of organic solvents to investigate whether the separation was feasible. When employing acetone, ethanol, dimethylsulfoxide, or dimethylformamide, the organic solvent-extract combination formed a single phase. However, when benzene, ethyl acetate, or n-hexane was added to the extract, the mixture separated into an organic and an aqueous phase and the pigments remained in the aqueous phase. On the other hand, when polyethylene glycol-2,000 (PEG-2000) and sodium citrate were added to the extract, the mixture was separated into three layers, with the majority of the flavonoids migrating to the top layer and 53% of the extract's glucose migrating to the bottom layer. The top layer had significant antioxidant activity, whereas the bottom layer showed no antioxidant activity. The glucose recovery in the bottom layer increased as the molecular weight of PEG increased and the highest recovery (67%) was observed when PEG-8,000 was added. The highest flavonoid separation was observed with PEG-2,000, followed by PEG-8,000 and PEG-400. The flavonoid separation when PEG-2,000 was added resulted in a flavonoid recovery of 48% and 0.2% from the top and bottom layers, respectively. Examining the effect of the separated solution using the agar disc diffusion method on yeast cell growth confirmed that the addition of the extract, the top, and the bottom layer did not inhibit cell growth.

Production of Cyclodextrin Homologues Using Aqueous Two-Phase System

  • Chang, Woo-Jin;Koo, Yoon-Mo;Park, Sung-Sik
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.2 no.2
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    • pp.97-100
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    • 1997
  • Cyclodxtrin homologues(CDs), produced by cyclodextrin glycosyltransferase(CGTase), were simultaneously partitioned in aqueous two-phase system(ATPS). Partition coefficients of CDs were measured in PEG/dextran systems. Phosphate, citrate, sulfate were tested as salt. ATPS of PEG/salt and PEG/dextran had the partition coefficients of the CDs, larger than unity. However, PEG/dextran system was observed better than PEG/salt as CGTase activity decreased sharply with salt concentration. Enzymatic rection occurred mainly in PEG-rich bottom phase because of the low partition coefficient of CGTase. The resulting CDs transferred to the PEG-rich top phase, obeying the diffusional partition. In the ATPS of 7% PEG(M.W.40, 000), 7mg/ml of CDs were obtained in top phase at 4.5 hours.

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Studies on the Dimensional Stabilization of Wood -Especially by the Solution of Different Composition by PEG Molecular Weight- (목재(木材)의 치수 안정화(安定化)에 관(關)한 연구(硏究) -Polyethylene Glycol의 혼합액(混合液)을 중심(中心)으로-)

  • Oh, Joung Soo;Cheon, Cheol
    • Journal of Korean Society of Forest Science
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    • v.76 no.2
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    • pp.119-126
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    • 1987
  • This study was carried out to elucidate the desirable PEG molecular weight and it's blending methods which can promote the dimensional stabilization of Corpus controversa, Quercus variabilis and Prunus sargentii. The results may be summarized as follows: 1. PEG polymer loading in woods was affected by specific gravity of wood. And the PEG polymer loading was satisfactory except in Quercus variabilis, which shows the blending method of PEG V was proper. 2. Bulking coefficiency of PEG V was high in Corpus controversa and Prunus sargentii, and it is necessary to paint or coat water-proofing wood preservative: for high bulking coefficiency of Quercus variabilis. 3. In the treatment of PEG V, the antishrink efficiency of Prunus sargentii was 82.59% and that of Quercus variabilis 62.79%. 4. Dimensional stabilization of hardwoods did not have apparant relation with PEG blending method. 5. Judging from results, PEG-400 and PEG-1000 would be enough for dimensional stabilization of hardwood having high specific gravity if other factors are considered well.

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Polyethylene Glycol Plus Electrolytes with Stimulant Laxative in Paediatric Faecal Disimpaction: A Randomised Controlled Study

  • Acharyya, Bhaswati C;Bhattacharyya, Chandrayee;Mukhopadhyay, Meghdeep;Acharyya, Saumyabrata
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.24 no.2
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    • pp.230-237
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    • 2021
  • Functional constipation is common in the paediatric population all over the world. Effective disimpaction to evacuate the impacted faecal matter forms an essential initial step in the management of constipation. Though different regimens of polyethylene glycol 3350 with electrolytes (PEG+E) are accepted as the prime medication for disimpaction, response is not always satisfactory. A randomised prospective study was undertaken, in a tertiary paediatric Gastroenterology centre to find out the outcome of a 2-day disimpaction when a stimulant laxative sodium picosulphate was added to PEG3350+E (PEG+E+PS group) and comparing it with the outcome using PEG3350+E (PEG+E group) alone. Hundred and one children were randomised into two groups to receive PEG+E+PS and PEG+E. Results revealed that PEG+E+PS group proved significantly superior to PEG+E group in most of the efficacy-parameters in terms of disimpaction as well as long-term management of constipation. Though stimulant laxatives are being used for disimpaction, comparative data are lacking. This was the 1st such comparative study looking at the efficacy of these two processes of disimpaction along with long term effect on treatment.

Gas Permeation Properties of $CO_2$ Through Poly(ethylene Glycol) Diacrylate/Poly(Propylene Glycol) Diacrylate Membrane (Poly(ethylene glycol)diacrylate/poly(propylene glycol)diacrylate 막의 이산화탄소 기체 투과특성에 관한 연구)

  • Rhim Ji Won;Nam Sang Yong;Lee Sun Yong;Yun Tae Il
    • Membrane Journal
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    • v.14 no.3
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    • pp.250-257
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    • 2004
  • PEG(poly(ethylene glycol)) acrylate/PPG(poly(propylene glycol)) acrylate (PEG/PPG) was prepared using UV induced photopolymerization method to investigate gas permeation properties of the membrane. The effect of PPG content on the solubility, diffusivity, and permeability of $CO_2$, $O_2$, and $N_2$ in PEG/PPG membrane is reported at $25^{\circ}C$ and $35^{\circ}C$. PEG/PPG (9:1) membrane exhibits $CO_2$ permeability coefficient of 28.9 barrer and $CO_2$/$N_2$ pure gas selectivity of 57.9 at $25^{\circ}C$. Permeability coefficient of increased with increasing with PPG content in the membrane. PEG/PPG (5:5) membrane shows $CO_2$ permeability coefficient of 78.9 barrer and $CO_2$/$N_2$ pure gas selectivity of 33.2 at $25^{\circ}C$.

Properties of cotton fabric treated with $TiO_2$/PEG ($TiO_2$/PEG처리 면직물의 특성)

  • 김정진;장정대
    • Textile Coloration and Finishing
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    • v.14 no.3
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    • pp.53-58
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    • 2002
  • Cotton fabric was treated with TiO$_2$-PEG600 mixed solution by pad-dry-cure and wet-fixation process to improve the performance properties as well as antibiosis effect and its laundering durability. In this paper, the effects of concentration of $TiO_2/PEG$ and fixation process were investigated on laundering durability and properties of cotton fabric treated with glyoxal. As the concentration of $TiO_2/PEG$ increased fixation, W.I., K/S of treated cotton fabric increased. Application of wet-fixation method provided a further improvement in fixation, laundering durability of treated cotton fabric.

Synthesis of Aniline from Nitrobenzene and Fe(CO)5 with PEG/γ-Al2O3 as Phase Transfer Catalyst (PEG/γ-Al2O3 상이동 촉매상에서 니트로벤젠과 Fe(CO)5로부터의 아닐린 합성)

  • Oh, So-Young;Lee, Hwa-Su;Park, Dae-Won;Park, Sang-Wook;Shin, Jung-Ho
    • Applied Chemistry for Engineering
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    • v.4 no.1
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    • pp.144-152
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    • 1993
  • Immobilized polyethylene glycols onto metal oxides such as ${\gamma}-Al_2O_3$, ${\alpha}-Al_2O_3$, $SiO_2$ and $TiO_2$ were used as phase transfer catalysts for the room temperature synthesis of aniline from nitrobenzene and ironpentacarbonyl. The amount of attached PEG molecules increased with specific surface area of metal oxides. Among the immobilized catalysts tested PEG/${\gamma}-Al_2O_3$ showed the highest activity. The reaction rate increased with the chain length of PEG mole-cules and the aqueous NaOH concentration. Mechanistic study carried out using infrared spectrometer revealed that the role of PEG was to increase the formation of $HFe(CO)_4{^-}$ ion, which is known as active species, and its movement from aqueous to organic phase.

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Germination Characteristics of PEG Priming Seed in Barley (Hordeum vulgare L.) (PEG로 프라이밍 된 보리(Hordeum vulgare L.)종자의 발아특성)

  • 이성춘;박문수;배창휴
    • Korean Journal of Plant Resources
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    • v.15 no.1
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    • pp.18-25
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    • 2002
  • These experiments were conducted to evaluate the variability of seed germination, and seedling growth of PEG priming barley. The average germination percentage(AGP) of PEG priming seed was higher than control, but those were low with extend the treatment period. The AGP of washing seed after PEG priming was higher than unwashed seed, and that of redried seed after priming was lower than control. The germination time of priming seed was short compare to control seed, and that was prolonged with extend the priming period, and that of washing seed after priming was shortening, and that of redried seed after priming was prolonging. The emergence percentage(EP) of priming seed was higher than control, and the emergence time was shortest in 50% field moisture capacity soil. The seedling and root length of priming seed was shorter than control.

Effect of Polycaprolactone on the Mechanical Properties of PEG/HMX Propellant (Polycaprolactone이 PEG/HMX 추진제의 기계적 성질에 미치는 영향)

  • 정병훈;홍명표;임유진
    • Journal of the Korean Society of Propulsion Engineers
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    • v.2 no.3
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    • pp.62-69
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    • 1998
  • Mechanical properties of polyethyleneglycol(PEG)/cyclo-tetramethylene tetranitramine(HMX) propellant were studied by adding polycaprolactone(PCP) and silane derivatives as coupling agent. Mechanical properties of the propellant were enhanced by increasing the content of PCP which was partially replaced with PEG. PCP/HMX propellant showed 17% increase in maximum tensile strength and 59% increase in elongation compared to those of PEG/HMX propellant. However, as the content of PCP was increased, the hydrolytic stability of this propellant was found to be deteriorated due to the ester group of PCP by measuring hardness drop of cured propellant and swell ratio difference of PEG/PCP binder stored at $40^{\cire}C$ and 90% relative humidity. Hardness of the PEG/PCP/HMX propellant was decreased with increasing triethoxysilyl propionitrile(TESPN) and dinitrosalicylic acid (DNSA) content from accelerated aging at $60^{\cire}C$.

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PEGYLATION: Novel Technology to Enhance Therapeutic Efficacy of Proteins and Peptides (PEG 접합: 단백질 및 펩타이드 치료제의 약효를 증가시키는 새로운 기술)

  • Park, Myung-Ok;Lee, Kang-Choon
    • Journal of Pharmaceutical Investigation
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    • v.30 no.2
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    • pp.73-83
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    • 2000
  • Polyethylene glycol (PEG) is a water soluble, biocompatible, non-toxic polymer and PEGylation is a well established technique for the modification of therapeutic proteins and peptides. PEG-protein drugs have been extensively studies in relation to therapies for various diseases: cancer, inflammation and others. The covalent attachment of PEG to proteins and peptides prolonged plasma half-life, reduced antigenicity and immunogenicity, increased thermal and mechanical stability, and prevented degradation by enzymes. Several chemical groups for general and site specific conjugation have been exploited to activate PEG for amino group, carboxyl group, and cysteine groups. PEGylation of many proteins and peptides have been studied to enhance their properties for the potential uses. Also, the different positional isomers in several PEG-proteins have shown the difference in vivo stability and biological indicating that the site of PEG molecule attachment is one of the important factor to develop PEG-proteins as potential therapeutic agents.

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