• Title/Summary/Keyword: PC/A ratio

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Clinical Prediction Based on HPV DNA Testing by Hybrid Capture 2 (HC2) in Combination with Liquid-based Cytology (LBC)

  • Junyangdikul, Pairoj;Tanchotsrinon, Watcharaporn;Chansaenroj, Jira;Nilyaimit, Pornjarim;Lursinsap, Chidchanok;Poovorawan, Yong
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.2
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    • pp.903-907
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    • 2013
  • Primary screening by HPV DNA testing is an effective method for reducing cervical cancer and has proven more sensitive than cytology. To advance this approach, many molecular methods have been developed. Hybrid capture 2 provides semi-quantitative results in ratios of relative light units and positive cutoff values (RLU/PC). Twenty-five thousand and five patients were included in this study to analyze the correlation between the ratio of RLU/PC and stage of cervical dysplasia. The results show that the RLU/PC ratios ranged from 0-3500 while almost normal cases, ASC-US and ASC-H, had values below 200. Of those samples negative for cytology markers, 94.6% were normal and their RLU/PC ratios were less than 4. With an RLU/PC ratio greater than 4 and less than or equal to 300, the percentages in all age groups were normal 53.6%, LSIL 20.2%, ASC-US 17.2%, HSIL 6.13%, ASC-H 2.72%, and AGC 0.11%, respectively. In contrast, 64.0% of samples with a RLU/PC ratio greater than 300 and less than or equal to 3500 were LSIL. These results should contribute to cost effective cervical cancer management strategies. Further studies of associations with particular HPV genotypes would be useful to predict the risk of progression to cancer.

Influence of Dietary Linolenic Acid/linoleic Acid Ratio on Brain Lipid Composition and Acetylcholinestease Activity in Different Aged Rats (Linolenic acid/linoleic acid 비율이 다른 식이가 연령이 다른 흰쥐의 뇌구조지방 조성과 Acetylcholinesterase 활성에 미치는 영향)

  • 윤군애
    • Journal of Nutrition and Health
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    • v.28 no.8
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    • pp.706-716
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    • 1995
  • This study was undertaken to investigate the influence of age and dietary linolenic acid content and the linolenic acid/linoleic acid (LAN/LA) ratio on the brain lipid composition and membrane-bound enzyme, acetylcholinesterase(AchE) activities. AchE was selected as a test case for the relationship between cell lipid composition and cell membrane function. The male rats were fed diets with 0.2, 0.4, 0.6 of LNA/LA ratio within 8% LNA(H-LNA) or 4% LNA(L-LAN) of total fatty acid content for different feeding period(1, 4, 12 month). The fats used s source were sesame oil, perilla oil, soybean oil and beef tallow. The AchE activity of brain crude synaptosomal fraction was reduced with advancing age, showing 20-30% reduction in 12M compared with 1 M, and the P/C ratio was reduced in old rats. In 1 and 4 monthed rats, AchE activites was higher in H-LAN-0.2 and L-LNA-0.2 and 0.4 group. In accordance with rising of AchE activities was higher in H-LNA-0.2 and L-LNA-0.2 and 0.4 group. In accordance with rising of AchE activities, the PC/PE ratio increasedin those groups. Paricularly in L-LNA, the PC/PE ratio increased as the AchE activites for decline of membrane fluidity with increasing cholesterol and decreasing P/C ratio when rats were old. Also, AchE activity increaed with increasing PC/PE ratio which depended on the dietary LNA/LA ratio within each LNA content. Therefore, it is concluded that the lipid composition of cell membrane influenced the AchE activiteis, which was mediated by aging and the modification of dietary LNA/LA ratio.

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A design of embedded PC-Fi system with interactive remote control (인터렉티브 원격제어 기능을 갖는 임베디드 PC-Fi 시스템 설계)

  • Bae, Min-Eui;Shin, Ok-Keun
    • Journal of Advanced Marine Engineering and Technology
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    • v.40 no.1
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    • pp.55-61
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    • 2016
  • As the price-performance ratio of embedded PCs improves, the benefits of the PC-Fi can be maximized by designing an embedded PC-Fi system. In this paper presents the design of an embedded PC-Fi that can be manipulated by a remote controller based on mobile devices such as smart phones or tablets. Additionally, an interactive control system and its GUI, through which the user can select and play music as they like at ease, are presented. The case that a large amount of music is stored in the PC-Fi system requires a function allowing the user to easily select the music they want to listen to. In order to implement this function, a DB containing detailed information of each track can be used to find the location of the desired music with keywords provided by the user. In this proposed system, the embedded PC-Fi system and remote controller are mutually connected via a WiFi network, and more than one user can remotely control the embedded system with their own mobile device.

Statistical Analysis of Pc1 Pulsations Observed by a BOH Magnetometer

  • Kim, Jiwoo;Hwang, Junga;Kim, Hyangpyo;Yi, Yu
    • Journal of Astronomy and Space Sciences
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    • v.37 no.1
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    • pp.19-27
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    • 2020
  • Pc1 pulsations are important to consider for the interpretation of wave-particle interactions in the Earth's magnetosphere. In fact, the wave properties of these pulsations change dynamically when they propagate from the source region in the space to the ground. A detailed study of the wave features can help understanding their time evolution mechanisms. In this study, we statistically analyzed Pc1 pulsations observed by a Bohyunsan (BOH) magneto-impedance (MI) sensor located in Korea (L = 1.3) for ~one solar cycle (November 2009-August 2018). In particular, we investigated the temporal occurrence ratio of Pc1 pulsations (considering seasonal, diurnal, and annual variations in the solar cycle), their wave properties (e.g., duration, peak frequency, and bandwidth), and their relationship with geomagnetic activities by considering the Kp and Dst indices in correspondence of the Pc1 pulsation events. We found that the Pc1 waves frequently occurred in March in the dawn (1-3 magnetic local time (MLT)) sector, during the declining phase of the solar cycle. They generally continued for 2-5 minutes, reaching a peak frequency of ~0.9 Hz. Finally, most of the pulsations have strong dependence on the geomagnetic storm and observed during the early recovery phase of the geomagnetic storm.

Synthesis and Photovoltaic Properties of a Low Band Gap Polymer for Organic Solar Cell (유기태양전지를 위한 작은 밴드갭 고분자의 합성과 광전특성)

  • Woo, Yong-Ho;Lee, Hyo-Sang;Park, Sungnam;Choi, E-Joon;Kim, BongSoo
    • Polymer(Korea)
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    • v.39 no.1
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    • pp.71-77
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    • 2015
  • We synthesized a low band gap alternating copolymer containing electron-rich units (i.e. dithienosiloles and benzodithiophenes) and electron-deficient units (i.e. difluorobenzothiadiazoles) for high performance organic solar cells. The polymer was prepared by the Stille coupling reaction and characterized using $^1H$ NMR, GPC, TGA, UV-visible absorption spectroscopy, and cyclic voltammetry. Solar cells were fabricated in a structure of ITO/PEDOT:PSS/polymer: $PC_{70}BM/Al$ with five different blending ratios of polymer and $PC_{70}BM$ (1:1.5, 1:2, 1:3, 1:3.5 and 1:4 by weight ratio). The best efficiency was achieved from the 1:3 ratio of polymer and $PC_{70}BM$ in the photoactive layer, and TEM revealed that there is an optimal nanoscale phase separation between polymer and $PC_{70}BM$ in the 1:3 ratio blend film.

The Effects of Different Substrates on the Growth, Yield, and Nutritional Composition of Two Oyster Mushrooms (Pleurotus ostreatus and Pleurotus cystidiosus)

  • Hoa, Ha Thi;Wang, Chun-Li;Wang, Chong-Ho
    • Mycobiology
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    • v.43 no.4
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    • pp.423-434
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    • 2015
  • The study was conducted to compare the effects of different agro-wastes on the growth, yield, and nutritional composition of oyster mushrooms Pleurotus ostreatus (PO) and Pleurotus cystidiosus (PC). Seven substrate formulas including sawdust (SD), corncob (CC), sugarcane bagasse (SB) alone and in combination of 80 : 20, 50 : 50 ratio between SD and CC, SD and SB were investigated. The results indicated that different substrate formulas gave a significant difference in total colonization period, characteristics of fruiting bodies, yield, biological efficiency (BE), nutritional composition and mineral contents of two oyster mushrooms PO and PC. The results showed that increasing CC and SB reduced C/N ratio, and enhanced some mineral contents (Ca, P, and Mg) of substrate formulas. The increased amount of CC and SB of substrate formulas enhanced protein, ash, mineral contents (Ca, K, Mg, Mn, and Zn) of fruiting bodies of both mushrooms. Substrates with 100% CC and 100% SB were the most suitable substrate formulas for cultivation of oyster mushrooms PO and PC in which they gave the highest values of cap diameter, stipe thickness, mushroom weight, yield, BE, protein, fiber, ash, mineral content (Ca, K, and Mg) and short stipe length. However, substrate formula 100% CC gave the slowest time for the first harvest of both mushrooms PO and PC (46.02 days and 64.24 days, respectively). It is also found that the C/N ratio of substrate formulas has close correlation with total colonization period, mushroom weight, yield, BE and protein content of mushroom PO and PC.

The Age-Related Effect of n-6/n-3 Ratio of Dietary Fats on Lipid Levels and Prostaglandin Production in Rats (식이 다가 불포화 지방산의 n-6/n-3 비율에 의한 흰쥐의 지질수준 및 Prostaglandin 생성에 대한 연령별 비교)

  • 이준호
    • Journal of Nutrition and Health
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    • v.28 no.2
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    • pp.95-106
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    • 1995
  • The effects of various n-6/n-3 ratios(about 2, 4, 6, 8) of dietary fatty acids on various lipid levels and prostaglandin production were studied at the constant P/S ratio (1.5-1.6) in young (5 weeks old) and adult(8 months old) Sprague-Dawley rats using palm oil, safflower oil and sardine oil. The concentration of serum cholesterol tended to increase with the increasing n-6/n-3 ratio. The tendency of HDL-cholesterol levels was similar to serum cholesterol levels. These were not apparent differences between young and adults rats. Serum triglyceride levels increased according to increasing n-6/n-3 ratio in young rats. These were generally high in the adult rats compared with the young rats. Though liver cholesterol level tended to increase according to the increasing n-6/n-3 ratio in the young rats. The liver triglyceride level did not change according to the n-6/n-3 ratio. However, these levels were apparently higher in the adult than in the young rats. The fatty acid compositions of phosphatidylcholine(PC) were similar in serum and liver. The arachidonate/linoleate ratios in tissue PC were influenced by the n-6/n-3 ratio. They tended to be lower in the adult rats compared with the young rats. It was suggested that the activity of $\Delta$6-desturase was decreased by aging. Production of platelet thromboxane A2(TXA2)and aortic prostacyclin(PGI2) was not apparently influenced with n-6/n-3 ratio. Whereas the ratio of TXA2/PGI2 was the lowest value at 3.8 of n-6/n-3 ratio, expecially in the young rats. Thus this ratio seemed to be a desirable level to protect atherosclerosis. These results indicate that the lipid level and prostaglandin production were influenced not only by n-6/n-3 ratio(under constant P/S ratio) but by aging, particulary triglycerde level and arachidonic/linoleic acid ratio.

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Parallel lProcessing of Pre-conditioned Navier-Stokes Code on the Myrinet and Fast-Ethernet PC Cluster (Myrinet과 Fast-Ethernet PC Cluster에서 예조건화 Navier-Stokes코드의 병렬처리)

  • Lee, G.S.;Kim, M.H.;Choi, J.Y.;Kim, K.S.;Kim, S.L.;Jeung, I.S.
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.30 no.6
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    • pp.21-30
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    • 2002
  • A preconditioned Navier-Stokes code was parallelized by the domain decomposition technique, and the accuracy of the parallelized code was verified through a comparison with the result of a sequential code and experimental data. Parallel performance of the code was examined on a Myrinet based PC-cluster and a Fast-Ethernet system. Speed-up ratio was examined as a major performance parameter depending on the number of processor and the network communication topology. In this test, Myrinet system shows a superior parallel performance to the Fast-Ethernet system as was expected. A test for the dependency on problem size also shows that network communication speed in a crucial factor for parallel performance, and the Myrinet based PC-cluster is a plausible candidate for high performance parallel computing system.

Performance Characteristics of p-i-n type Organic Thin-film Photovoltaic Cell with Rubrene:CuPc Hole Transport Layer (Rubrene:CuPc 정공 수송층이 도입된 p-i-n형 유기 박막 태양전지의 성능 특성 연구)

  • Kang, Hak-su;Hwang, Jongwon;Kang, Yongsu;Lee, Hyehyun;Choe, Youngson
    • Korean Chemical Engineering Research
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    • v.48 no.5
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    • pp.654-659
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    • 2010
  • We have investigated the effect of rubrene-doped CuPc hole transport layer on the performance of p-i-n type bulk hetero-junction photovoltaic device with a structure of ITO/PEDOT:PSS/CuPc: rubrene/CuPc:C60(blending ratio 1:1)/C60/BCP/Al and have evaluated the current density-voltage(J-V) characteristics, short-circuit current($J_{sc}$), open-circuit voltage($V_{oc}$), fill factor(FF), and energy conversion efficiency(${\eta}_e$) of the device. By rubrene doping into CuPc hole transport layer, absorption intensity in absorption spectra decreased. However, the performance of p-i-n organic type bulk hetero-junction photovoltaic device fabricated with crystalline rubrene-doped CuPc was improved since rubrene shows higher bandgap and hole mobility compared to CuPc. Increased injection currents have effected on the performance improvement of the present device with energy conversion efficiency(${\eta}_e$) of 1.41%, which is still lower value compared to silicone solar cell and many efforts should be made to improve organic photovoltaic devices.

Effects of Dietary Docosahexaenoic Acid Levels on the Brain Phospholipids and Serum and Liver Lipid Compositions in Rats (Docosahexaenoic Acid의 수준별 섭취가 흰쥐의 뇌인지질 및 혈청, 간의 지질조성에 미치는 영향)

  • 이준호;김현숙
    • Journal of Nutrition and Health
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    • v.34 no.2
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    • pp.132-140
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    • 2001
  • The effects of various dietary docosahexaenoix acid(DHA) levels on the brain phospholipids and serum and liver lipid compositions were studied in rats using DHA concentrated oil and corn oil as a control for 4 weeks. Serum total cholesterol and HDL cholesterol levels tended to be the lowest by adding 20% DHA to corn oil. Serum triglyceride levels significantly decreased by adding 30% DHA. Liver cholesterol and triglyceride levels were apparently decreased in the groups added above 20% DHA, especially, the lowest at adding 30% DHA. Brain weight and phospholipid content were not different among groups. The ratios of arachidonic to linoleic acids in serum and liver phosphatidylcholine(PC) were significantly decreased by adding dietary DHA and showed a flat form above 20% of dietary DHA. DHA levels of serum PC were gradually increased according to dietary DHA level. The fatty acid compositions of the brain PC and phosphatidylethanolamine(PE) did not appear any changes with accordance of the dietary DHA levels. However, compared with those of serum and liver in general, linoleic and arachidonic acid levels were very low. Oleic acids were apparently higher than those in the other tissues. DHA were higher than those in the other tissues rigardless of the dietary DHA, especially in brain PE. The ratios of arachidonic to linoleic acid were not apparent tendency in brain PC and PE. However, the ratios of brain PE were above 2 times higher than those of brain PC. As the results, the hypolipidemic effects of dietary DNA were remarkable in liver. Especially in regard to tendency of liver lipid levels and desaturation indices in serum and liver PC, the effects indicated significantly higher by adding 20-30% DHA to diet(n-6/n-3 ratio, about 4-7). Thus, in this study, these dietary DHA levels seemed to be appropriate, at least in these lipid paramenters.(Korean J Nutrition 34(2) : 132∼140, 2001)

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