• Title/Summary/Keyword: PARs

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Acute Toxicity of Heavy Metals, Tributyltin, Ammonia and Polycyclic Aromatic Hydrocarbons to Benthic Amphipod Grandidierella japonica

  • Lee, Jung-Suk;Lee, Kyu-Tae;Park, Gyung-Soo
    • Ocean Science Journal
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    • v.40 no.2
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    • pp.61-66
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    • 2005
  • Benthic amphipod, Grandidierella japonica widely inhabits the Korean coastal waters and is developed as a standard test species for sediment toxicity tests. We exposed G. japonica to various pollutants including 4 kinds of inorganic metals (Ag, Cd, Cu and Hg), tributyltin [TBT], ammonia and 7 polycyclic aromatic hydrocarbon (PAH) compounds (acenaphthene, chrysene, fluoranthene, fluorene, naphthalene, phenanthrene and pyrene) to estimate the no observed effect concentration (NOEC) and the median lethal concentration (LC50) of each pollutant during the 96-hour acute exposure. Among all tested pollutants, TBT was most toxic to G. japonica, and Rg was most toxic among inorganic metals. The toxicity of pyrene to G. japonica was greatest among PAH compounds, followed by fluoranthene, phenanathrene, acenaphthene, fluorene and naphthalene. The toxicity of PAH compounds was closely related to their physico-chemical characteristics such as $K_ow$ and water solubility. G. japonica responded adequately to pollutant concentrations and exposure durations, and the sensitivity of G. japonica to various inorganic and organic pollutants was generally comparable to other amphipods used as standard test species in ecotoxicological studies, indicating this species can be applied in the assessment of environments polluted by various harmful substances.

Cervical Epidural Block Can Relieve Persistent Hiccups -Case report- (경부 경막외 신경차단을 이용한 2주간 계속된 딸꾹질의 치료 경험 -증례보고-)

  • Lee, Kyung-Jin;Park, Won-Sun;Chun, Tae-Wan;Kim, Chan;Nam, Yong-Taek
    • The Korean Journal of Pain
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    • v.8 no.1
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    • pp.131-134
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    • 1995
  • Hiccup is characterized by a myoclonus in the diaphragm, resulting in a sudden inspiration associated with an audible closure of the glottis. The reflex arc in hiccups comprises three pars: an afferent, a central and an efferent part. The afferent portion of the neural pathway of hiccup formation is composed of the vagus nerve, the phrenic nerve, and the sympathetic chain arising from T6 to T12. The hiccup center is localised in the brain stem and the efferent limb comprises phrenic pathways. All stimuli affecting the above mentioned reflex arc may produce hiccups. The pathogenesis of persistent hiccups is not known. Hiccup can present a symptom of a subphrenic abscess or gastric distention, and metabolic alterations may also cause hiccups. Numerous treatment modalities have been tried but with questionable success. We describe a patient whose persistant hiccups was treated successfully by a cervical epidural block.

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Immunolocalization of Allatotropin Neuropeptide in the Developing Brain of the Silk Moth Bombyx mori

  • Park, Cheolin;Lee, Bong-Hee
    • Animal cells and systems
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    • v.5 no.3
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    • pp.211-216
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    • 2001
  • Polyclonal antiserum against Manduca sexta allatotropin has been utilized to investigate the localization of allatotropin-immunoreactivity in the brain of the si1k moth Bombyx mori. Manduca sexta allatotropin-immunoreactive (Mas-AT-IR) neurons were found in all larval brains investigated, but not in prepupal, pupal and adult brains. In the larval stages, first appearance of Mas-AT-immunoreactivity w8s shown in the brain of first instar larvae, which contains four pairs of bilateral Mas-AT-IR cell bodies. Labeled neurons increased to six pairs in the second instar larval brain, including two pairs of median neurosecretory cells in the pars intercerebralis. In the third and fourth instar larvae, five pairs of labeled cell bodies were distributed throughout each brain. In the fifth instar, there were about ten pairs of bilateral cell bodies in the day-1 brain, about seven pairs in the day-3 brains, and five pairs in the day-5 brains, respectively. Mas-AT-labeling was observed in both axons within nervi corpora cavdiaci (NCC) 1+11 and corpora allata. This suggests that the Mas-AT produced from the brain neurons is transported via some axons of the NCC 1+11 and nervi corpora allati I to the corpora allata, which appears to be a main accumulation site for the Mas-AT neuropeptide in some brain neurons produced in B. mori.

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Risk factors for infectious bronchitis virus infection in laying flocks in three provinces of Korea: preliminary results

  • Pak, Son-Il;Kwon, Hyuk-Moo;Yoon, Hee-Jun;Song, Chang-Sun;Son, Young-Ho;Mo, In-Pil;Song, Chi-Yong
    • Korean Journal of Veterinary Research
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    • v.45 no.3
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    • pp.405-410
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    • 2005
  • To analyze and identify selected risk factors for infectious bronchitis virus (IBV) infection in the growing and laying period of laying-hen flocks, a longitudinal field study was conducted with 27 commercial flocks reared in three provinces of Korea during the period from May 2003 to April 2004. Using monitored data for IBV infection status among study flocks we computed the multivariate odds ratios (ORs) and their corresponding confidence intervals (CIs), and population attributable risks (PARs). Multivariate logistic regression showed significant risk increments for: continuous entry of chick (OR=1.9, 95% CI, 0.7-69.1) and operation years of the layer house greater than or equal to 5 years (OR=3.2, 95%CI, 1.6-389.9). No significant interaction was found between variables. The PAR suggested that continuous entry of chick (PAR=32%) and ${\geq}5years$ of house operation (PAR=84%) had the highest impacts on IB presence in laying-hen flocks under study. Of the two significant factors, however, operation year of the layer house lacks an easy applicability in preventing IB control strategies, and the possibility of confounder cannot be ruled out.

A Meta-Ontology for Automated Information Integration of Parts Libraries (부품 라이브러리 정보의 자동 통합을 위한 메타 온톨로지)

  • Cho, J.M.;Han, S.H.;Kim, H.
    • Korean Journal of Computational Design and Engineering
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    • v.11 no.4
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    • pp.273-288
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    • 2006
  • Information integration of heterogeneous digital parts libraries or electronic pars catalogs is one of issues in B2B procurements. We need to provide an integrated view for multiple information sources. Utilization of ontologies as the metadata descriptions of the information sources can provide an integrated view. However, in order to integrate independently developed ontologies, the mismatches among them should be resolved. In this paper, we propose an ontology of meta-concepts, i.e. meta-ontology. The meta-concepts play the role of vocabulary to describe the parts library ontologies and provide well-established ontological semantics that helps the ontology modelers to consistently identify parts library concepts and systematically structure them. Consequently, the meta-ontology reduces the differences in the way the parts knowledge is interpreted and ensures the mismatches are confined to manageable mis matches, so that a software program can merge automatically. Modeling ontologies of mold and die parts libraries for B2B e-commerce is taken as an example to show how to use the meta-ontology. We also discuss how a parts library mediation system can automatically merge the well-structured parts library ontologies.

Microphallus koreana n. sp. (Trematoda: Microphallidae) Transmitted by a Marine Crab, Macrophthalmus dilatatus

  • Guk, Sang-Mee;Chai, Jong-Yil;Sohn, Woon-Mok;Kim, You-Me;Sim, Seo-Bo;Seo, Min
    • Parasites, Hosts and Diseases
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    • v.46 no.3
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    • pp.165-169
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    • 2008
  • Microphallus species occur primarily as intestinal parasites of birds and mammals, and metacercariae of a new species belonging to this genus have been discovered from the crab, Macrophthalmus dilatatus, in the Republic of Korea. The metacercaria of this fluke was round with 2 thick walls, and the excysted one had mature genital organs. The adult flukes recovered from experimentally infected chicks had numerous intrauterine eggs, well-developed pars prostatica, widely bifurcating ceca, and prominent uterine bulge. After observing internal structures, it was concluded that this species is different from any other known Microphallus spp. Based on the morphology of metacercariae and adult flukes, we describe this specimen as a new species, Microphallus koreana n. sp.

Mortality Attributable to Second Hand Smoking in Morocco: 2012 Results of a National Prevalence Based Study

  • Tachfouti, Nabil;Najdi, Adil;Lyoussi, Badiaa;Nejjari, Chakib
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.6
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    • pp.2827-2832
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    • 2016
  • Purpose: To estimate the number of deaths attributable to second hand smoking (SHS) in Morocco in 2012. Materials and Methods: prevalence based study focusing on mortality from ischaemic heart disease (IHD) and lung cancer among non-smokers aged 35 and over. Prevalence of SHS among never smokers was gathered from a national cross sectional survey on tobacco and population attributable risk (PAR) was calculated by applying PARs to mortality. The analyses were stratified by sex, age and area of exposure. Results: Rates for exposure to SHS among men aged 35-64 years ranged from 20.0% at home to 57.4% at work. Among non-smoking Moroccans aged 35 and over, 233 (IC: 147 - 246) deaths were attributable to exposure to SHS; 156 (IC: 100 - 221) in women and 77 (IC: 44 -125) in men. A total of 173 (122 - 222) deaths were estimated to have been caused by exposure only at home, 34 (9 - 76) by exposure only at the work place and 26 (15 - 58) by exposure both at home and work places. Exposure to SHS could be responsible for 182 (128 - 237) deaths from IHD and 51 (19 - 109) from lung cancer. Conclusions: These data confirm that SHS needs urgent attention in Morocco.

The Nigrostriatal Tract between the Substantia Nigra and Striatum in the Human Brain: A Diffusion Tensor Tractography Study

  • Yeo, Sang Seok;Seo, Jeong Pyo
    • The Journal of Korean Physical Therapy
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    • v.32 no.6
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    • pp.388-390
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    • 2020
  • Objectives: The nigrostriatal tract (NST) connect from the substantia nigra pars compacta to the striatum. A few previous studies have reported on the NST in the Parkinson's disease using a proboblistic tractography method. However, no study has been conducted for identification of the NST using streamline DTT technique. In the current study, we used streamline DTI technique to investigate the reconstruction method and characteristics of the NST in normal subjects. Methods: Eleven healthy subjects were recruited in this study. The NST from the substantia nigra of the midbrain and the striatum of basal ganglia was reconstructed using DTI data. Fractional anisotropy, apparent diffusion coefficient (ADC) values and fiber numbers of the NST were measured. Results: In all subjects, the NST between the substantia nigra of the midbrain and the striatum. Mean values for FA, ADC, and tract volume were 0.460, 0.818, and 154.3 in the right NST, and 0.485, 0.818, and 176.3 in the left NST respectively. Conclusions: we reconstructed the NRT from the substantia nigra of the midbrain and the striatum of the basal ganglia using streamline tractography method. We believe that the findings and the proposed streamline reconstruction method of this study would be useful in future researches on the NST of the human brain.

Cervical Spine Malformations Associated With a 5q34-5q35.2 Micro-interstitial Deletion: A Case Report

  • Lee, Heewon;Kim, Joon Sung;Lim, Seong Hoon;Sul, Bomi;Hong, Bo Young
    • Annals of Rehabilitation Medicine
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    • v.42 no.6
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    • pp.884-887
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    • 2018
  • We report a female proband carrying a de novo 5q34-q35.2 deletion breakpoint, and review the unique skeletal phenotype and possible genotype related to this mutation. The patient presented with a persistent head tilt and limited head rotation. Non-contrast-enhanced three-dimensional computed tomography of the cervical spine revealed several malformations including a bone cleft in the right pars interarticularis, a bone defect in both C5 lamina and the transverse foramen at C2-C3, agenesis of the right articular process of C5, bony fusion of C4-C5, and subluxation of the craniocervical joints. Several deformities of the cervical spine seen in this patient have not been associated with the 5q deletion. A review of 5q-related mutations suggests that abnormalities associated with MSX2 gene might cause cervical spine abnormalities.

Noise and Timing Jitter Consideration in Microwave Photonic Systems (마이크로웨이브 포토닉 시스템에서의 잡음과 지터에 관한 연구)

  • Jung, Byung-Min;Lee, Seung-Hun;Chang, YuShin
    • Journal of IKEEE
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    • v.25 no.2
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    • pp.234-242
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    • 2021
  • In case implementation of microwave photonic (MWP) systems for phased array radars (PARs), noise and time delay error should be minimized to obtain accurate beam direction. Time delay error in MWP systems is generated from signal noise and timing jitter. In this paper, noise and timing jitter in MWP systems for PAR is researched, also according to the amplification of an erbium-doped fiber amplifier, noise and timing jitter variation is verified by an experiment. Timing jitter is decreased and SNR is increased if we amplify the signal by using an erbium-doped fiber amplifier, up to the amplification rate of signal and noise is similar.