• Title/Summary/Keyword: PAI

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Association of PAI-1 Polymorphism with Schizophrenia in Korean Population

  • Yoon, Seo-Hyun;Park, Hae-Jeong;Zheng, Longtai;Hong, Mee-Suk;Kim, Jong-Woo;Yim, Sung-Vin;Chung, Joo-Ho
    • Molecular & Cellular Toxicology
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    • v.2 no.3
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    • pp.212-215
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    • 2006
  • Several reports have suggested a possible relationship between blood coagulation factors and schizophrenia. Plasminogen activator inhibitor type 1 (PAI-1) belongs to a serine protease inhibitor family, which regulates fibrinolysis and proteolysis by inhibiting plasminogen activation. The purpose of this study was to investigate the association of polymorphisms of the PAI-1 gene with schizophrenia in Korean population. Two important polymorphisms (-675 4G/5G and -844 G/A) located on promoter region of the PAI-1 gene were analyzed on 178 schizophrenia patients and 226 controls. The genotypic and allelic associations of -675 4G/5G were found significant. Furthermore, haplotype analysis revealed significant result, which suggests that -675 4G/5G polymorphism might confer increased susceptibility for schizophrenia in Korean population.

Base Inhibitor를 이용한 고전도도의 PEDOT박막의 제작

  • Lee, Joon-Woo;Choi, Byoung-Blk;Choi, Sang-Il;Kim, Sung-Soo
    • Proceedings of the Korean Vacuum Society Conference
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    • 2012.02a
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    • pp.442-442
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    • 2012
  • PEDOT[Poly(3,4-Ethylenedioxythiophene)]박막의 제작은 산화촉매제를 이용한 기상중합(Vapor Phase Polymerization)방법을 통해 최근 활발히 연구되어 지고 있다. 기상중합된 PEDOT박막의 특성은 박막의 중합의 정도와 성장 형상에 따라 그 특성이 크게 좌우된다. PEODT박막의 효율적인 중합에 있어 산화촉매제의 균일한 도포는 매우 중요하다. PEDOT의 효율적인 중합과 균일도포를 위해 산화촉매제에 DUDO와 PEG-PPG-PEG를 첨가한 혼합용액을 제작 VPP방법을 통해 PEDOT박막의 제작을 시도하였다. 그 결과 spin-coating 시 산화촉매 혼합용액의 균일한 도포가 관찰 되었으며 산화촉매제만 사용하여 제작된 박막에 비해 전도도와 막질이 향상된 PEDOT박막이 제작되었다. 이러한 결과는 산화촉매용액에 첨가된 PEG-PPG-PEG와 DUDO의 영향으로 PEG-PPG-PEG는 oxdiant용액의 균일 도포를 도왔으며 Inhibitor로 작용하는 DUDO는 PEDOT성장에 있어 불균일 결정성장을 억제하여 조밀한 PEDOT 박막 성장을 도운 것으로 생각된다. PEDOT 박막의 특성평가에는 Field Emission-Scanning Electron Microscopy, 4-Pointprobe, Optical microscopy 등이 사용되었다. 이러한 고전도도의 PEDOT박막을 OTFT의 전극소재로 사용한다면 OTFT소자의 성능 향상에있어 크게 기여 할 것으로 기대된다.

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Effect of Ethylene Adsorbent on Apple Fruit Quality during Storage (사과과실 저장성에 미치는 에틸렌흡착제의 효과)

  • Ahn, Young-Jik;Choi, Jong-Seung;Min, Byung-Hoon;Yi, Kyoung-UK
    • The Journal of Natural Sciences
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    • v.8 no.2
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    • pp.169-173
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    • 1996
  • This experiment was conducted to investigate the effect of ethylene adsorbent removing ethylene gas produced from apple fruits in poly ethylene film bag storage. The treatment of ethylene adsorbent was not effected the change in soluble solids and organic acid content of fruits. The fruit softening was remarkably delayed by the absorbent treatment, and the more amount of it was the more effective. The ethylene evolution and respiration of fruits reduced or decreased by this treatment during storage. The ethylene adsorbent for 'Fuji' apple fruit was effective more than 30g per 10kg fruits.

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Manufacture and Quality Characteristics of Wild Grape Wine (머루 발효주의 제조 및 품질 특성)

  • Cho, Chang-Ho;Song, Jung-Hwa;Lee, Eun-Na;Lee, Jong-Soo
    • The Journal of Natural Sciences
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    • v.19 no.1
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    • pp.37-44
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    • 2008
  • To develop a new functional wine, manufacture and quality characteristics of wild grape wine were investigated. Ethanol contents of wild grape wine was 11.0%, and total acidity and volatile acid content were 0.63% and 0.0402%, respectively. Antioxidant activity of the wild grape wine which is related in anti-aging functionality, was 41.6%. From this results, we concluded that the wild grape wine is a high valuable wine.

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Analysis of Tendencies on WLAN Security Technology (무선랜 보안 기술 및 운영 현황 분석)

  • Kim, Su-Jin;Seo, Jong-Kyun;Han, Ki-Cheon;Jung, Hoe-kyung
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2013.10a
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    • pp.685-687
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    • 2013
  • Today, as wireless communications devices such as laptops, smart phones are generalized, wireless LAN has been widely installed in the corporate office conference rooms, industrial warehouses, Internet-ready classrooms, and even in a coffee shop. Though a wired network can be accessed and attacked only by the physical penetration, the wireless network which can be accessed anywhere within the reach of anyone has relative vulnerability by unauthorized users' attack. To defend these vulnerabilities, the introduction of WIDS / WIPS is required. In this paper, we recognize the limitations of WLAN security technology, review the current technology trends and propose the solutions in the future security problems.

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Manufacture and Electrical Properties of PAI-MCS-A Nano-hybrid Enamel for Insulation (절연용 PAI-MCS-A 나노하이브리드 에나멜의 제조와 전기적특성)

  • Han, Se-Won;Han, Dong-Hee;Kim, Suk-Jun;Jang, He-Mi;Kang, Dong-Pil
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.06a
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    • pp.497-498
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    • 2008
  • 에너지절약에 대한 중요성과 관심으로 효율을 높이고 인버터 구동에 대한 서지내구성이 강화된 전동기용 절연소재의 개발에 관심이 커지고 있다. 최근 나노기술의 발달로 전동기용 에나멜 절연재에 나노입자를 강화하여 성능과 효율의 향상이 크게 개선되고 있다. 본 연구에서는 졸겔 제조법으로 PAI-MCS-A계 나노 하이브리드형 에나멜을 제조하여 기존 수지와의 전기적 특성을 비교 분석하였다. 강화입자로 선택한 나노 MCS의 조성을 최대 30wt% 범위에서 메트릭스 수지와의 상안정성이 확인되었다. 특히 내아크성, 트래킹 시험에서 우수한 내구성이 나타났으며 이는 전동기용 에나멜 및 전력용 절연코팅용으로 사용이 기대된다.

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Design of Cloud-based on Machine Socialization System (클라우드 기반 Machine Socialization 시스템 설계)

  • Hwang, Jong-sun;Kang, In-shik;Lim, Hyeok;Yang, Xi-tong;Jung, Hoe-kyung
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2016.05a
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    • pp.573-574
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    • 2016
  • Before the Machine Socialization System used to connected between server and router. However, the data flow increases due to the poor performance of the router increased traffic, as a result, the loss of data when the problem occurred Collaboration between devices increases that have been interrupted. This action moves the server connected to the router is required to solve these problems. In this paper, by utilizing the cloud server to reduce bottlenecks proposed a system that can reduce the loss of data during cooperation between devices. In addition, by dividing the management unit and the sensor using the virtualization technology, we designed a system that can efficiently make use of the resource.

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Tribological characteristics of short fiber reinforced composites (단섬유 보강 복합재료의 트라이볼로지 특성)

  • 윤재륜
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.12 no.6
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    • pp.1238-1245
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    • 1988
  • Friction and wear characteristics of short fiber reinforced and particulate filled composites were investigated experimentally. Two kinds of fiber composites, chopped graphite fiber reinforced PAI(polyamide-imide) and glass fiber reinforced PAI, and a particulate composite, TiO$_{2}$ powder filled PAI, were selected for the friction and wear test since these are important engineering materials based on a new high temperature engineering plastic. All the specimens were cut into proper size for cylinder-on-plate type wear test. Frictional forces were measured by employing a load transducer and wear rates were calculated by measuring weight loss during wear test. The experimental results are reported in this paper and carefully discussed to explain the friction and wear behavior qualitatively. The frictional behavior is interpreted by considering four basic friction components which are believed to the genesis of friction and the wear behavior is explained by applying delamination theory of wear.

Hormonal Regulation of Leptin, Resistin, and Plasminogen Activator Inhibitor-1 Gene Expression in 3T3-L1 Adipocytes

  • Lee, Hyun-Jung;Kim, Yang-Ha
    • Preventive Nutrition and Food Science
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    • v.9 no.4
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    • pp.336-341
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    • 2004
  • Leptin, resisitn and PAI-1 (plasminogen activator inhibitor-1) are synthesized and secreted by rodent fat cells and recently postulated to be an important link to obesity. This study was conducted to characterize the hormonal regulation of leptin, resistin, and PAI-1 gene expression in the 3T3-L1 adipocytes. The cells were treated with 0.5 $\mu$M insulin, 1 $\mu$M dexamethasone (Dex), or 0.05 $\mu$M triiodothyronine (T3) for 72 hours. The mRNA levels of each peptide were measured by semi-quantitative RT-PCR. The mRNA level of the leptin-producing ob gene was significantly increased by insulin, Dex, and T3 by 3.2-, 3.1- and 2.7-fold, respectively, compared to the control (p < 0.05). The level of resistin mRNA was increased by insulin, Dex, and T3 by 2.7-, 2.5- and 2-fold, respectively, compared to the control (p < 0.05). Likewise, the level of PAI-1 mRNA was significantly increased by insulin, Dex, and T3 compared to the control (p < 0.05). Taken together, our results suggest that insulin, Dex, and T3 may regulate the gene expression of leptin, resistin, and PAI-1 in 3T3-L1 adipocytes.

Keyword Weight based Paragraph Extraction Algorithm (키워드 가중치 기반 문단 추출 알고리즘)

  • Lee, Jongwon;Joo, Sangwoong;Lee, Hyunju;Jung, Hoekyung
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2017.10a
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    • pp.504-505
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    • 2017
  • Existing morpheme analyzers classify the words used in writing documents. A system for extracting sentences and paragraphs based on a morpheme analyzer is being developed. However, there are very few systems that compress documents and extract important paragraphs. The algorithm proposed in this paper calculates the weights of the keyword written in the document and extracts the paragraphs containing the keyword. Users can reduce the time to understand the document by reading the paragraphs containing the keyword without reading the entire document. In addition, since the number of extracted paragraphs differs according to the number of keyword used in the search, the user can search various patterns compared to the existing system.

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