• Title/Summary/Keyword: PA12

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Effects of Dietary Buffering Characteristics and Protected or Unprotected Acids on Piglet Growth, Digestibility and Characteristics of Gut Content

  • Bosi, P.;Jung, H.J.;Han, In K.;Perini, S.;Cacciavillani, J.A.;Casini, L.;Creston, D.;Gremokolini, C.;Mattuzzi, S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.12 no.7
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    • pp.1104-1110
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    • 1999
  • We condicted two experiments to evaluate the interaction among fumaric acid (FA), protected acids (PA), or no additional acid (NO) and two different levels of acid buffering capacity (BC) in diets for 14-d-old weaned pigs. BC was varied substituting mono-calcium phosphate and calcium sulfate for dicalcium phosphate and calcium carbonate. In the high BC diet plus PA, FA was also added. In Exp. 1, 48 gilts were raised for 31 days on the six diets, evaluating growth performance and fecal digestibility. In Exp. 2, 42 gilts were raised. With each diet three subjects were sacrificed after 19 days and four after 38 days. In addition, six subjects were sacrificed at weaning. Growth and carcass performance, ileal digestibility, bacterial populations and pH in the gut were assessed. The piglet performance and stomach, ileal and cecal pH, and empty body composition were not affected by the diets. Empty body composition other than ash content was affected by piglet age (p<0.01). The BC did not influence digestibility. The dietary inclusion of PA improved fecal digestibility of protein (p<0.05) compared to the addition of FA and NO. Ileal digestibility slightly increased with both acid additions (p<0.10), the groups receiving PA showing the higher values. Piglets fed diets with low BC had lower Lactobacillus and E. coli counts in the ileum (p=0.07) and higher Lactobacillus in the colon (p=0.08). Acidified diets tended to reduce E. coli counts in the ileum (p=0.10) and increased Lactobacillus in the colon (p=0.09). The addition in the diet of PA increased Lactobacillus in the ileum compared to the sole addition of free fumaric acid (p=0.07). The addition of protected acids, combined with free fumaric acid in the case of high BC diets, increased protein digestibility and Lactobacillus counts and reduced E.coli counts. Only some changes in the concentration of bacterial population can be expected with a diet of low BC.

Designing mobile personal assistant agent based on users' experience and their position information (위치정보 및 사용자 경험을 반영하는 모바일 PA에이전트의 설계)

  • Kang, Shin-Bong;Noh, Sang-Uk
    • Journal of Internet Computing and Services
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    • v.12 no.1
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    • pp.99-110
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    • 2011
  • Mobile environments rapidly changing and digital convergence widely employed, mobile devices including smart phones have been playing a critical role that changes users' lifestyle in the areas of entertainments, businesses and information services. The various services using mobile devices are developing to meet the personal needs of users in the mobile environments. Especially, an LBS (Location-Based Service) is combined with other services and contents such as augmented reality, mobile SNS (Social Network Service), games, and searching, which can provide convenient and useful services to mobile users. In this paper, we design and implement the prototype of mobile personal assistant (PA) agents. Our personal assistant agent helps users do some tasks by hiding the complexity of difficult tasks, performing tasks on behalf of the users, and reflecting the preferences of users. To identify user's preferences and provide personalized services, clustering and classification algorithms of data mining are applied. The clusters of the log data using clustering algorithms are made by measuring the dissimilarity between two objects based on usage patterns. The classification algorithms produce user profiles within each cluster, which make it possible for PA agents to provide users with personalized services and contents. In the experiment, we measured the classification accuracy of user model clustered using clustering algorithms. It turned out that the classification accuracy using our method was increased by 17.42%, compared with that using other clustering algorithms.

Study on the Characteristics of Height Growth by PHV Age -Using longitudinal data of age 7 to 18- (PHV 연령별 신장 발육의 특징에 관한 연구 -7~18세의 종단적 자료를 이용하여-)

  • Park, Ju-Mi;Kim, Myung
    • Korean Journal of Health Education and Promotion
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    • v.8 no.2
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    • pp.74-86
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    • 1991
  • This study tried to clear the characteristics of height growth pattern depending on Peak Height Velocity age in early, average and late groups. And in it, height growth tendency of girl students in age 7 to 18 years old was compared and investigated in order to know influencing factors, menarcheal age relation. The samples were senior girl students at high school in Seoul. Longitudinal data and survey data were collected in August, 1990. The results could be summarized as follows: 1. On distance curve, the height growth line in early group tended to be the highest and in late group the lowest. On the other hand, on velocity curve late group showed the highest peak and early group showed the lowest peak. In late group, velocity curve was too steep. Of course, these early, average and late groups were classified by PHV age. 2. In these three groups, late group showed the most growth amount per year. However, on distance curve, early group showed higher line than late group. Perhaps this means that peak growth amount in late group might have an effect on mean. 3. Growth amount of adolescence spurt age in these three groups was 6.86cm at age 9(early group), 7.27cm at l1(average group) and 7.65cm at 13(late group). In early group, because. PHV age came too early, it was difficult to find exact adolescence spurt period. In early group, the adolescence spurt period is considered to come at about age 7 to 9. In average group, at 9 to 11 and at 12 to 13 in late group. Especially, spurt of late group was remarkable. 4. When the growth amount of PA, before PA and after PA was compared, growth amount of PA in all three groups was about 20%. In early group, growth amount of APV tended to be large and in late group, that of APV tended to be large and in late group, that of BPV was large. In average group, growth amount of BPV was larger than that of APV. 5. For the purpose of comparing total height growth amount of these groups at age 18, the height growth was assumed to be over. And then, the difference of three groups was studied but it's not significant. 6. Although the difference between height growth and family environment, dietary habits, exercise, disease history in these three groups was investigated, only the income was significant. The significance of all the other factors was not approved. 7. When menarcheal age was compared with PA, generally we know menarche appeared after 1∼2 years of PHV age. But in case of early group, the difference between PHV age and menarcheal age was 5.34 years. In average group, 2.45 years and 0.82 years in late group.

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Influence of Processing on Morphology, Electrical Conductivity and Flexural Properties of Exfoliated Graphite Nanoplatelets-Polyamide Nanocomposites

  • Liu, Wanjun;Do, In-Hwan;Fukushima, Hiroyuki;Drzal, Lawrence T.
    • Carbon letters
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    • v.11 no.4
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    • pp.279-284
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    • 2010
  • Graphene is one of the most promising materials for many applications. It can be used in a variety of applications not only as a reinforcement material for polymer to obtain a combination of desirable mechanical, electrical, thermal, and barrier properties in the resulting nanocomposite but also as a component in energy storage, fuel cells, solar cells, sensors, and batteries. Recent research at Michigan State University has shown that it is possible to exfoliate natural graphite into graphite nanoplatelets composed entirely of stacks of graphene. The size of the platelets can be controlled from less than 10 nm in thickness and diameters of any size from sub-micron to 15 microns or greater. In this study we have investigated the influence of melt compounding processing on the physical properties of a polyamide 6 (PA6) nanocomposite reinforced with exfoliated graphite nanoplatelets (xGnP). The morphology, electrical conductivity, and mechanical properties of xGnP-PA6 nanocomposite were characterized with electrical microscopy, X-ray diffraction, AC impedance, and mechanical properties. It was found that counter rotation (CNR) twins crew processed xGnP/PA6 nanocomposite had similar mechanical properties with co-rotation (CoR) twin screw processed or with CoR conducted with a screw design modified for nanoparticles (MCoR). Microscopy showed that the CNR processed nanocomposite had better xGnP dispersion than the (CoR) twin screw processed and modified screw (MCoR) processed ones. It was also found that the CNR processed nanocomposite at a given xGnP content showed the lowest graphite X-ray diffraction peak at $26.5^{\circ}$ indicating better xGnP dispersion in the nanocomposite. In addition, it was also found that the electrical conductivity of the CNR processed 12 wt.% xGnP-PA6 nanocomposite is more than ten times higher than the CoR and MCoR processed ones. These results indicate that better dispersion of an xGnP-PA6 nanocomposite is attainable in CNR twins crew processing than conventional CoR processing.

Degradation from Polishing Damage in Ferroelectric Characteristics of BLT Capacitor Fabricated by Chemical Mechanical Polishing Process (화학적기계적연마 공정으로 제조한 BLT Capacitor의 Polishing Damage에 의한 강유전 특성 열화)

  • Na, Han-Yong;Park, Ju-Sun;Jung, Pan-Gum;Ko, Pil-Ju;Kim, Nam-Hoon;Lee, Woo-Sun
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.06a
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    • pp.236-236
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    • 2008
  • (Bi,La)$Ti_3O_{12}$(BLT) thin film is one of the most attractive materials for ferroelectric random access memory (FRAM) applications due to its some excellent properties such as high fatigue endurance, low processing temperature, and large remanent polarization [1-2]. The authors firstly investigated and reported the damascene process of chemical mechanical polishing (CMP) for BLT thin film capacitor on behalf of plasma etching process for fabrication of FRAM [3]. CMP process could prepare the BLT capacitors with the superior process efficiency to the plasma etching process without the well-known problems such as plasma damages and sloped sidewall, which was enough to apply to the fabrication of FRAM [2]. BLT-CMP characteristics showed the typical oxide-CMP characteristics which were related in both pressure and velocity according to Preston's equation and Hernandez's power law [2-4]. Good surface roughness was also obtained for the densification of multilevel memory structure by CMP process [3]. The well prepared BLT capacitors fabricated by CMP process should have the sufficient ferroelectric properties for FRAM; therefore, in this study the electrical properties of the BLT capacitor fabricated by CMP process were analyzed with the process parameters. Especially, the effects of CMP pressure, which had mainly affected the removal rate of BLT thin films [2], on the electrical properties were investigated. In order to check the influences of the pressure in eMP process on the ferroelectric properties of BLT thin films, the electrical test of the BLT capacitors was performed. The polarization-voltage (P-V) characteristics show a decreased the remanent polarization (Pr) value when CMP process was performed with the high pressure. The shape of the hysteresis loop is close to typical loop of BLT thin films in case of the specimen after CMP process with the pressures of 4.9 kPa; however, the shape of the hysteresis loop is not saturated due to high leakage current caused by structural and/or chemical damages in case of the specimen after CMP process with the pressures of 29.4 kPa. The leakage current density obtained with positive bias is one order lower than that with negative bias in case of 29.4 kPa, which was one or two order higher than in case of 4.9 kPa. The high pressure condition was not suitable for the damascene process of BLT thin films due to the defects in electrical properties although the better efficiency of process. by higher removal rate of BLT thin films was obtained with the high pressure of 29.4 kPa in the previous study [2].

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Follow up study of pulmonary function after pneumonectomy (일측 폐절제술후 폐기능의 추적관)

  • Park, Jae-Gil;Kim, Se-Hwa;Lee, Hong-Gyun
    • Journal of Chest Surgery
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    • v.16 no.4
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    • pp.539-546
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    • 1983
  • Maximal expiratory flow-volume [MEFV] curves were studied in 22 patients who underwent pneumonectomy with various pulmonary lesions, such as lung cancer, bronchiectasis and tuberculosis etc, at the preoperative stage and 3 week, 4 month and 12 month after pneumonectomy for the analysis of the reduction and progressive improvement of postoperative ventilatory function. And the factors affecting them like as age difference and the site of pneumonectomy were also analyzed. From these curves peak flow rate [PF R], maximal expiratory flows at 25% and 50% of expired forced vital capacity [V25, V50] and forced vital capacity [FVC] were obtained. In addition, partial pressure of oxygen and carbon dioxide in arterial blood were measured. The results were as follows; 1. The mixed type, especially obstructive type of ventilatory impairment was observed at 3 week after operation. For 1 year of postpneumonectomy FVC was increased by 12.3% of predicted compared to 2.6% of predicted V50. 2. The improvement of FVC during 1 year of postpneumonectomy showed decreasing tendency with the increase of age but the changes of V25 and V50 were unremarkable. 3. The differences of immediate postoperative reduction and progressive improvement of ventilatory capacity after right and left pneumonectomy were analyzed. The reduction of V50, V25 and FVC at 3 week of postoperation were greater in patients with right pneumonectomy [20.9%, 18.2% and 26.2% of predicted] than in patients with left pneumonectomy 16.5%, 18.2% and 18.1%]. But there was no significant difference of these values at 12 month after pneumonectomy. 4. The partial pressure of oxygen in arterial blood [$PaO_2$] was decreased by 13.6 mmHg at 3 week after pneumonectomy compared to the preoperative stage but returned to the normal range within 4 month after pneumonectomy. However, TEX>$PaCO_2$ was within the normal range during 1 year of postoperation.

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A Case Study on the Polar Low Developed over the Sea Near Busan on 11~12 February 2011 (2011년 2월 11~12일 부산 근해에서 발달한 극저기압에 대한 사례연구)

  • Lee, Jae Gyoo;Kim, Hae-Min;Kim, Yu-Jin
    • Atmosphere
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    • v.26 no.2
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    • pp.301-319
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    • 2016
  • The evolutionary process of the polar low, which caused the heavy snowfall in the East Coast area on 11~12 February 2011, was investigated to describe in detail using synoptic weather charts, satellite imageries, and ERA (European Centre for Medium-Range Weather Forecasts Re-Analysis) -Interim reanalysis data. It was revealed that 1) the polar low was generated over the sea near Busan where a large cyclonic shear in the inverted trough branched from the parent low existed, 2) during the developing and mature stages, there was a convectively unstable region in the lower layer around the polar low and its south side, 3) the polar low was developed in the region where the static stability in the 500~850 hPa layer was the lowest, 4) the result from the budget analysis of the vorticity equation indicated that the increase in the vorticity at the lower atmosphere, where the polar low was located, was dominated mainly by the stretching term, 5) the warm core structure of the polar low was identified in the surface-700 hPa layer during the mature stage, 6) there was a close inverse relationship between a development of the polar low and the height of the dynamic tropopause over the polar low, and 7) for generation and development of the polar low, large-scale circulation systems, such as upper cold low and its combined short wave trough, major low (parent low), and polar air outbreak, should be presented, indicating that the polar low has the nature of the baroclinic disturbance.

Application of the Onsite Earthquake Early Warning Technology Using the Seismic P-Wave in Korea (P파를 이용한 지진 현장 경보체계기술의 국내 적용)

  • Lee, Ho-Jun;Lee, Jin-Koo;Jeon, Inchan
    • Journal of the Society of Disaster Information
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    • v.14 no.4
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    • pp.440-449
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    • 2018
  • Purpose: This study aims to design and verify an onsite EEWS that extracts the P-wave from a single seismic station and deduce the PGV. Method: The P-wave properties of Pd, Pv, and Pa were calculated by using 12 seismic waveform data extracted from historic seismic records in Korea, and the PGVs were computed using empirical equation on the P properties - PGV relationship and compared with the observed values. Results: Comparison of the observed and estimated PGVs within the alarm level shows the error rate of 86.7% as minimum. By reducing the PTW to 2 seconds, the alarm time can be shortened by 1 second and the seismic blind zone near the epicenter can be shortened by 6 Km. Conclusion: Through this study, we confirmed the availability of the on-site EEWS in Korea. For practical use, it is necessary to develop regression formula and algorithm reflect local effect in Korea by increasing the number of seismic waveform data through continuous observation, and to eliminate the noise from the site.

Gromwell (Lithospermum erythrorhizon) Attenuates High-Fat-Induced Skeletal Muscle Wasting by Increasing Protein Synthesis and Mitochondrial Biogenesis

  • Ji-Sun Kim;Hyunjung Lee;Ahyoung Yoo;Hang Yeon Jeong;Chang Hwa Jung;Jiyun Ahn;Tae-Youl Ha
    • Journal of Microbiology and Biotechnology
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    • v.34 no.3
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    • pp.495-505
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    • 2024
  • Gromwell (Lithospermum erythrorhizon, LE) can mitigate obesity-induced skeletal muscle atrophy in C2C12 myotubes and high-fat diet (HFD)-induced obese mice. The purpose of this study was to investigate the anti-skeletal muscle atrophy effects of LE and the underlying molecular mechanism. C2C12 myotubes were pretreated with LE or shikonin, and active component of LE, for 24 h and then treated with 500 μM palmitic acid (PA) for an additional 24 h. Additionally, mice were fed a HFD for 8 weeks to induced obesity, and then fed either the same diet or a version containing 0.25% LE for 10 weeks. LE attenuated PA-induced myotubes atrophy in differentiated C2C12 myotubes. The supplementation of LE to obese mice significantly increased skeletal muscle weight, lean body mass, muscle strength, and exercise performance compared with those in the HFD group. LE supplementation not only suppressed obesity-induced skeletal muscle lipid accumulation, but also downregulated TNF-α and atrophic genes. LE increased protein synthesis in the skeletal muscle via the mTOR pathway. We observed LE induced increase of mitochondrial biogenesis and upregulation of oxidative phosphorylation related genes in the skeletal muscles. Furthermore, LE increased the expression of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha and the phosphorylation of adenosine monophosphate-activated protein kinase. Collectively, LE may be useful in ameliorating the detrimental effects of obesity-induced skeletal muscle atrophy through the increase of protein synthesis and mitochondrial biogenesis of skeletal muscle.

The Respiratory and Hemodynamic Effect of Prone Position in Patients with ARDS (급성호흡부전증후군에서 Prone Position의 호흡 및 혈류역학적 효과)

  • Lim, Chae-Man;Koh, Youn-Suck;Jung, Bok-Hyun;Lee, Sang-Do;Kim, Woo-Sung;Kim, Dong-Soon;Kim, Won-Dong
    • Tuberculosis and Respiratory Diseases
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    • v.44 no.5
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    • pp.1105-1113
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    • 1997
  • Background : Prone position improves oxygenation in some patients with ARDS. According to some authors, prone position can also improve the deteriorated hemodynamics induced by PEEP. But these respiratory and hemodynamic effects of prone position has not yet been fully established. Methods : Twentythree consequtive patients with ARDS(M : F= 11 : 12, $62.1{\pm}20.8yrs$) were the subjects for this study. ABGA, static compliance of the respiratory system, mean arterial pressure and pulse rate were obtained in supine position and at 5min, 0.5h and 2h of prone position. Positive respiratory response was defined as 20mmHg or more increase in $PaO_2/FIO_2$ within 2h of prone position. Early of late respiratory responses were defined if the positive response was observed within of after 3 day of ARDS onset, respectively. Positive hemodynamic response was defined as 10mmHg or more increase in mean arterial pressure at 5min of prone position. Results : Fifteen patients (65%) showed positive respiratory response. In the respiratory responders, $PaO_2$ was $69.8{\pm}17.6mmHg$ in supine position, $83.2{\pm}22.6mmHg$ in prone position 0.5h, $96.8{\pm}22.7mmHg$ in prone position 2h(p<0.001), and $PaO_2/FIO_2$ was $108{\pm}41mmHg$, $137{\pm}57mmHg$, $158{\pm}50mmHg$, respectively(p=0.001). Age, sex, cause of ARDS, supine $PaO_2$ and $PaO_2/FIO_2$ were not different between the respiratory responders and the nonresponders. The respiratory responders, however, showed higher mean arterial pressure than the nonresponders($91.1{\pm}13.1mmHg$ vs. $76.0{\pm}18.7mmHg$, p=0.035), and tendency of higher survival rate(9/15 vs. 2/8, p=0.074). Static compliance of the respiratory system was decreased in prone position 0.5h($28.4{\pm}7.9ml/cm$ $H_2O$ vs. $23.8{\pm}7.6ml/cm$ $H_2O$, p=0.007). The overall rate of early response(n=23) and late response(n=11) were similar(14/23 vs. 7/11, p>0.05). But patient without early response showed late response only in 25%(1/4), while patient with early response showed late response in 85.7%(6/7)(p=0.072). Five patients(22%) showed positive hemodynamic response, two of them being respiratory nonresponders. There were no differences in the baseline mean arterial pressure or the level of PEEP applied in supine between the hemodynamic responders and the hemodynamic nonresponders. Conclusions : Prone position either improved oxygenation or increased arterial pressure in significant proportion of patients with ARDS. And the respiratory response to prone position was thought to be determined in the early stage of ARDS.

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