• 한국정보전자통신기술학회논문지
• /
• 제12권3호
• /
• pp.299-305
• /
• 2019

본 연구는 고령화와 젊은층의 이탈로 인한 농경사회에서 고령 및 여성 인력의 애로사항을 해결해주기 위해 시작되었다. 기존에 나와있는 농업용 고소리프트의 경우 전문 자격증 및 조작의 어려움과 평지가 아닌 불균형적인 도로 혹은 작업환경에 노출된 위험성과 여성들도 쉽고 효율적으로 생산적 농업을 할 수 있도록 하기 위하여 선행연구를 바탕으로 진행하였다. 먼저 농업용 포크리프트의 목적인 물체를 이용한 견인 성능 예측 모델을 통하여 시뮬레이션을 진행하고, 견인 성능 모델 수식을 이용하여 실험이 진행되고 있는 경남 김해시의 토양(점착력 34.125kPa, 내부마찰각 35.294deg, 외부마찰각 13.620deg, 부착력 5.750kPa, 평균 원추지수 0-15cm cl, 1001.8kPa)에 맞추었다. 시뮬레이션용 포크리프트의 경우 농업용 전동식 포크리프트의 구동력 및 운동저항 예측 모델링을 수식화하고 이를 바탕으로 모터 제어 드라이브는 AC모터 전용 드라이브인 1232E 모델을 적용, 프로그래밍을 통해 두 개의 드라이버를 각각 마스터와 슬레이브로 구분지어 구동할 수 있도록 하였고 메인 PCB에는 모터구동, 유압구동, 각종 출력을 제어할 수 있도록 시뮬레이션용 모델을 제작하였다. 제작된 시뮬레이션용 모델은 현재 지속적인 시뮬레이션과 수정 및 보완을 진행하고 있으며, 추후 본 연구를 바탕으로 보다 안전하고 효율성이 뛰어난 농업용 전동식 포크리프트의 개발을 위하여 연구를 지속할 예정이다.

• 한국지반환경공학회 논문집
• /
• 제22권12호
• /
• pp.41-50
• /
• 2021

본 연구의 목적은 모래와 타이어칩 혼합토의 반복하중조건 전후 공학적 특성 변화를 파악하는 것이다. 반복하중 시, 시료에 함유된 타이어칩 함량 및 모래와 타이어칩 입자 간의 크기비에 따른 최대전단탄성계수의 변화를 정량화 하고자, 전체 중량 대비 타이어칩 중량을 0, 10, 20, 40, 60, 100%로 하여 시료를 조성하였으며, 타이어칩 평균입경 대비 모래의 평균입경(입자크기비)을 0.44, 1.27, 1.87, 4.00으로 설정하여 혼합토를 조성하였다. 초기 상대밀도 50%의 시료를 floating wall 형태의 몰드에 조성 후, 공기압 축기(air compressor), 압력 패널(pressure panel) 및 뉴메틱 밸브(pneumatic valve)를 이용하여 정하중 재하(=50kPa), 반복하중 재하(=50-150kPa), 정하중 재하(=400kPa) 및 제하 순으로 실험이 이루어 졌다. 위의 실험이 진행됨에 따라 시료의 침하량과 전단파속도를 측정하였다. 시험 결과, 모래-타이어칩 혼합토에 가해지는 반복하중은 시료를 이루는 입자 간 접촉을 타이어칩-타이어칩 또는 타이어칩-모래에서 모래-타이어칩 또는 모래-모래로 전환시켰으며, 이로 인해 타이어칩 함량 40%에서 가장 큰 최대전단탄성계수의 증가를 확인하였다. 또한 입자크기비가 감소함에 따라 동일 타이어칩 함량에서 반복하중 시 최대전단탄성계수 증가량은 증가하였다.

• 한국수산과학회지
• /
• 제47권3호
• /
• pp.302-312
• /
• 2014

This article describes the design and performance characteristics of a broadband ultrasonic mosaic transducer. We focus on the improved bandwidth in the high frequency band of a previously designed broadband ultrasonic transducer (Lee et al., 2014). The improvement in the pulse-echo bandwidth was achieved by employing twelve $2{\times}2$ element subarrays, operating at different resonance frequencies, and utilizing the mosaic array concept. We found that the -6 dB and -12 dB bandwidths of the newly developed broadband ultrasonic mosaic transducer, were up to 155% and 170% of the previously designed model, with a quality factor of 1.71 and 1.25, respectively. The averaged TVR (transmitting voltage response), SRT (receiving sensitivity), and FOM (figure of merit) values in a nearly flat transmitting response band, from 45 to 105 kHz providing a -12 dB bandwith of 60 kHz, were 163.3 dB (re $1{\mu}Pa/V$ at 1 m), -192.8 dB (re $1V/{\mu}Pa$), and -30.9 dB, respectively.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권9호
• /
• pp.5403-5408
• /
• 2013

Objective: CXCL12 exerts a wide variety of chemotactic effects on cells. Evidence indicates that CXCL12, in conjunction with its receptor, CXCR4, promotes invasion and metastasis of tumor cells. Our objective was to explore whether the CXCL12-CXCR4 biological axis might influence biological behavior of pancreatic cancer cells. Methods: Miapaca-2 human pancreatic cancer cells were cultured under three different conditions: normal medium (control), medium + recombinant CXCL12 (CXCL12 group), or medium + CXCR4-inhibitor AMD3100 (AMD3100 group). RT-PCR was applied to detect mRNA expression levels of CXCL12, CXCR4, matrix metalloproteinase 2 (MMP-2), MMP-9, and human urokinase plasminogen activator (uPA). Additionally, cell proliferation and invasion were performed using CCK-8 colorimetry and transwell invasion assays, respectively. Results: CXCL12 was not expressed in Miapaca-2 cells, but CXCR4 was detected, indicating that these cells are capable of receiving signals from CXCL12. Expression of extracellular matrix-degrading enzymes MMP-2, MMP-9, and uPA was upregulated in cells exposed to exogenous CXCL12 (P<0.05). Additionally, both proliferation and invasion of pancreatic cancer cells were enhanced in the presence of exogenous CXCL12, but AMD3100 intervention effectively inhibited these processes (P<0.05). Conclusions: The CXCL12-CXCR4 biological axis plays an important role in promoting proliferation and invasion of pancreatic cancer cells.

• Journal of Chest Surgery
• /
• 제33권1호
• /
• pp.7-19
• /
• 2000

Background :To assess the accuracy of Electron-Beam Tomography(EBT) in following evaluation of the pulmonary vascular system after a shunt operation in the cyanotic con-genital heart disease with pulmonary stenosis or pulmonary atresia. Material and Method : Sixteen patients(M:F=11:5) who received Blalock-Taussig(n=8) bidirectional cavo-pulmonary shunt(n=10) and unifocalization (n=2) were ncluded in the study. We evaluated the patency of the shunt the morphology of intrapericardial and hilar pulmonary arteries(PA) peripheral pulmonary vascularity by background lung attenuation and the abundance of arterial & venous collateral. Angiography(n=12) and echocardiography(n=20) were used as the gold standard for the comparison of EBT results. Result: EBT was consistent with angiogram/ echo in 100% of the evaluation for the patency of the shunt and in 12(by angiogram 100%) and 19(by echo 95%) for the detection the hypoplasia stenosis or interruption of central PA In measuring of PA EBT and angiogram corrlated(r=0.91) better than EBT-echo(r=0.88) or echo-angiogram(r=0.72) Abundant systemic arterial collateral were noted in 4 and venous collateral in 3 cases. In evaluating the peripheral pulmonary vascularity the homogenous and normal-ranged lung attenuation(m=6) decreased but homo-genous attenuation(n=1) segment-by-sgment heterogeneous attenuation(n=3) homogenous but asymmetrical attenuation(n=3) segment-by-segment heterogeneous attenuation(n=3) homogenous but asymmetrical attenuation(n=3) and venous congestion(n=2) were observed nd 12 of them were compatible with the blood flow pattern revealed by cardiac catheterization. Conclusion: EBT was accurate in the integrated evaluation of the pulmonary vascular system after the shunt including the patency of the shunt operaion the morphology and dimension of the central and hilar PAs and the loco-regional pulmonary flow in the lung parenchyma. It suggests the useful information about the need of secondary shunt operation the proper timing time for total repair and the need of interventional procedure prior to total repair.

• 한국방사선학회논문지
• /
• 제15권6호
• /
• pp.883-889
• /
• 2021

본 연구는 2020년 5월부터 2020년 12월까지 복부초음파 검사를 위해 내원한 101명의 환자를 대상으로 하였다. 횡파탄성측정검사법을 이용하여 초음파 검사 시 초음파 영상(에코 패턴, 비장비대, 간염) 소견에 따른 탄성도를 알아 알아보고자 하였다. 에코 패턴의 정상 그룹의 횡파탄성측정값은 5.75±1.58 kPa였으며, 에코 패턴의 비정상 그룹은 8.84±4.94 kPa로 에코 패턴 비정상 그룹에서 횡파탄성측정값이 높게 나타났다(p<0.05). 정상 비장 크기에서 간 탄성도 값은 6.33±2.54 kPa였으며, 비장비대의 간 탄성도 값은 13.73±5.48 kPa로 나타났다. 비장비대일 경우 간 탄성도 값이 높게 나타났으며, 통계적으로 유의미한 차이가 있었다(p<0.05). 비장 크기가 증가할수록 간 탄성도 값이 1.485배, 간염이 진행될수록 간 탄성도 값이 1.573배 증가하는 것으로 나타났다(p<0.05). 초음파 영상 소견과 횡파탄성측정법 간 일치도 분석 결과 Kappa 값이 0.922(p<0.05)로 높게 나타났으며, 두 검사 방법 간에 높은 일치도를 보였다. 간 초음파 소견과 함께 횡파탄성측정법 검사의 간 탄성도 값을 추가적으로 비교한다면 간 섬유화 진단에 있어 많은 도움이 될 것으로 생각된다.

• 분석과학
• /
• 제12권5호
• /
• pp.441-446
• /
• 1999

무우 유식물의 자엽에서 Abscisic acid(ABA). ABA plus cyeloheximide(CH)와 ABA plus polyamine(PA) 처리로 유도되는 아미노산의 변화를 분석하였다. ABA 처리로 봄무우에서는 총 아미노산의 농도가 증가되었고, 겨울무우에서는 감소되었다. 봄무우에서는 친수성 아미노산인 proiine, glycine, serine과 cysteine 등이 증가되었고(특히 proline), 반면 겨울무우에서는 cysteine, leucine와 phenylalanine이 증가되었다(특히 cysteine과 leucine). CH는 ABA가 유도시킨 탈수에 대항할 수 있는 단백질의 합성을 방해하여 아미노산의 축적을 초래하였다. PA처리는 반대로 봄무우에서는 총 아미노산의 농도가 감소되었고, 겨울무우에서는 증가되었다. 이상의 결과는 축적된 친수성 아미노산과 단백질이 스트레스에 대항하여 탈수의 적응을 유도하였고, PA은 ABA에 의한 탈수 스트레스의 적응능력을 조절한다고 본다.

• 대한불안의학회지
• /
• 제2권2호
• /
• pp.122-127
• /
• 2006

Objective : We examined the putative association between the psychological symptoms and hypoxemia in hospitalized pneumoconiosis patients. Methods : One hundred and nine hospitalized pneumoconiosis patients were divided into two groups according to their level of hypoxemia (PaO2); hypoxemic group consisted of 47 patients with PaO2 lower than 80 mmHg, and comparative group consisted of 62 patients with higher than 80 mmHg. All of them were interviewed with the Hamilton Depression Rating Scale (HAM-D), and completed the Symptom Checklist-90items-Revised (SCL-90-R) and the State-Trait Anxiety Inventory (STAI). The medical data (PaO2, PaCO2, Hb, and Hct), number of hospital days and socio-demographic data as well as scores of the three psychological measurements were compared between the two groups. Results : Hypoxemic patients with lower PaO2 showed higher scores in the HAM-D (p=0.01) and stateanxiety subscale of the STAI (p<0.05). Values of hemoglobin and hematocrit were negatively correlated with levels of trait-anxiety (p<0.05). Thirty patients (27.5%) of total subjects suffered from depression (higher than 18 in the HAM-D), and 46.8% of hypoxemic patients were depressed, whereas 12.9% of comparative group patients were depressed (p=0.01). Conclusion : These results suggest that depression and anxiety might be associated with the hypoxemic mechanism in pneumoconiosis patients.

• Asian Pacific Journal of Cancer Prevention
• /
• 제14권5호
• /
• pp.3093-3099
• /
• 2013

Background: Phytic acid (PA) is a polyphosphorylated carbohydrate that can be found in high amounts in most cereals, legumes, nut oil, seeds and soy beans. It has been suggested to play a significant role in inhibition of colorectal cancer. This study was conducted to investigate expression changes of ${\beta}$-catenin and cyclooxygenase-2 (COX-2) and cell proliferation in the adenoma-carcinoma sequence after treatment with rice bran PA by immunocytochemistry. Materials and Methods: Seventy-two male Sprague-Dawley rats were divided into 6 equal groups with 12 rats in each group. For cancer induction two intraperitoneal injections of azoxymethane (AOM) were given at 15 mg/kg bodyweight over a 2-weeks period. During the post initiation phase, two different concentrations of PA, 0.2% (w/v) and 0.5% (w/v) were administered in the diet. Results: Results of ${\beta}$-catenin, COX-2 expressions and cell proliferation of Ki-67 showed a significant contribution in colonic cancer progression. For ${\beta}$-catenin and COX-2 expression, there was a significant difference between groups at p<0.05. With Ki-67, there was a statistically significant lowering the proliferating index as compared to AOM alone (p<0.05). A significant positive correlation (p=0.01) was noted between COX-2 expression and proliferation. Total ${\beta}$-catenin also demonstrated a significant positive linear relationship with total COX-2 (p=0.044). Conclusions: This study indicated potential value of PA extracted from rice bran in reducing colonic cancer risk in rats.

• 대기
• /
• 제23권3호
• /
• pp.331-346
• /
• 2013

A case study of mesoscale snowfall with polar low signature during 25~26 December 2010 in South Korea is presented. The data used for analysis include surface and upper level weather charts, rain gauge, sea surface temperature, satellite imagery, sounding, and global $1^{\circ}{\times}1^{\circ}$ reanalysis data. The system initiated with a surface trough near the bay of Bohai but quickly intensified to become a polar low within 12 hours. The polar low moved southeastward bringing snowfall to southwestern Korea. There was strong instability layer beneath 800 hPa but baroclinicty was weak and disappeared as the low progressed onto land. Shortwave at 500 hPa and the surface trough became in-phase which hindered the development of the polar low while it approached Korea. However, there were strong tropopause folding (~500 hPa) and high potential vorticity (PV), which allowed the system to maintain its structure and dump 20.3 cm of snow in Jeonju. Synoptic, thermodynamic, dynamic, and moisture analyses reveal that polar low developed in an area of baroclinicity with strong conditional instability and warm air advection at the lower levels. Further, the development of a surface trough to polar low was aided by tropopause folding with PV advection in the upper level, shortwave trough at 500 hPa, and moisture advection with low-level jet (LLJ) of 15 m $s^{-1}$ or more at 850 hPa. Maximum snowfall was concentrated in this region with convection being sustained by latent heat release.