• Journal of the Korean Geotechnical Society
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• v.18 no.1
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• pp.127-132
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• 2002

Shaking table tests are performed on model group piles to investigate the mechanics of dynamic pile-soil interaction, and to evaluate the dynamic group pile effect. Tests are executed on a single pile as well as group piles($3\times3$) by varying a pile spacing from 3D to 8D. A lumped mass is located on top of piles to simulate a superstructure. Dynamic p-y curves of the single pile and the group piles are obtained from the tests and compared with the backbone slopes of API cyclic p-y curves. From the comparisons, dynamic pile group effects are evaluated in terms of a pile spacing, a shaking frequency, and a shaking intensity.

• Korean Journal of Clinical Laboratory Science
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• v.52 no.1
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• pp.69-77
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• 2020

The tumor suppressor gene, p53, is inactivated in the human hepatocellular carcinoma cells line, Hep3B. Berberine has been reported to inhibit the proliferation of cancer cells. This study examined whether apoptosis was induced in berberine-treated Hep3B cells and observed the association between apoptosis and the expression of p53 and DNA methyltransferase (DNMT). The cell viability was measured using an MTT assay. Apoptosis of Hep3B was measured using annexin V flow cytometry. Berberine-treated cells were examined for their DNMT enzymatic activity, mRNA expression, and protein synthesis. The p53 levels were examined by Western blot analysis. The berberine treatment resulted in increased Hep3B cell death and apoptosis in a time- and dose-dependent manner. The DNMT3b activity, mRNA expression, and protein levels all decreased after the berberine treatment. In contrast, the p53 protein levels increased with a concomitant decrease in DNMT3b. No change in the expression of ERK was observed, but the P-ERK levels decreased in a dose dependent manner. These results indicate that a treatment of Hep3B cells with berberine can reduce the expression of DNMT3b, leading to an increase in the tumor suppressant gene p53 and an increase in cell apoptosis. This shows that berberine can effectively suppress the proliferation of liver cancer cells.

• Korean Journal of Adult Nursing
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• v.24 no.3
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• pp.294-304
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• 2012

Purpose: The purpose of this study was to examine the effects of taping therapy on the range of motion and pain of shoulders, physical functions and depression among hospitalized patients with stroke a geriatric hospital. Methods: The study design was a none equivalent control group pre-post test quasi-experimental design. The participants were 25 patients for experimental group and 25 patients for the control group. The period of this study was from March to July 2010. The twenty minute taping therapy was performed for twice a week for eight weeks. Results: The results showed that taping therapy was effective in range of motion shoulders (flexion: t=-5.81, p =.001, abduction: t=-3.69, p =.001) and pain of shoulders (rest: t=3.18, p = .003, movement: t=2.97, p =.005), grip (t=-3.22, p =.002) and balance (t=3.20, p =.002), and depression (t=3.24, p =.002). The variable of ADL (t=-1.99, p =.052) was not significant. Conclusion: The results of the taping therapy increased range of motion shoulders and grip and balance of physical functions, and decreased pain in shoulders and depression. The findings support that taping therapy can be used as a nursing intervention for stroke patients in practical nursing and communities.

• Journal of dental hygiene science
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• v.12 no.6
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• pp.696-701
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• 2012

The purpose of this study was to determine pH value of some alcoholic drinks sold in Korea and to provide the basic information which can cause dental erosion. Alcoholic drinks commercially sold were purchased from various big markets in Korea. The sorts of drinks tested in this study consisted of 5 brands of beers, 24 brands of makgeollis, 9 brands of wines and 12 brands of sojus. The test groups were selected randomly and the pH of each beverage was determined using a pH meter he each pH was measured. For statistical data, Mann-Whitney test was used to analyze difference for red wine and white wine and Kruskal-Wallis test was used to compare the pH of each test group. The result of this study was as followings: the mean pH of 5 brands of beers was 4.21, that of 24 brands of makgeollis 3.88, of 9 brands of wines 3.34 and of 12 brans of sojus 7.86. Each test group was significantly different (p<0.05). Except for soju groups, the test groups had a low pH value which can cause dental erosion. In terms of comparing between pH value of red wine and white wine, the result of this study represented that the mean pH of red wine was 3.45 and that of white wine was 3.21. This result showed the pH of two kinds of wine had a low pH which can lead to dental erosion and the difference of two wine were significantly different (p<0.05). As a result, some drinks sold in Korea have a high erosive potential on teeth since they have a comparatively low pH expect soju. Hence, when we consume some kinds of alcoholic drinks, we make sure to remember that the alcoholics which had a low pH, can have an effect on dental erosion that mean we should avoid to drink some alcoholic drinks with low pH for long time.

• The Transactions of the Korea Information Processing Society
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• v.6 no.8
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• pp.2098-2115
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• 1999

One of the unsolved problems in Neural Networks is the interpretation of hidden layers. This paper defines the Core-Net which has an input(p levels) and an output(q levels) with 2-layers as a basic circuit of neural network. In have suggested an equation, {{{{ {a}_{p,q} = {{q}^{2}} over {2}p(p-1)- { q} over {2 } (3 { p}^{2 } -7p+2)+ { p}^{2 }-3p+2}}}}, whichs ws the capacity of the Core-Net and have proved it by using the mathematical induction. It has been also shown that some of the problems with hidden layers can be solved by using the Core-Net and using simulation of an example.

• Sleep Medicine and Psychophysiology
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• v.1 no.1
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• pp.36-46
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• 1994

The event-related potentials are difined as the changes in voltage that occur at paticular time before, during and after something that happens in the physical world or some psychological processes. The possibilities of clinical applications of ERP are considered because the endogenous potentials such as P3 and contingent negative variation(CNV) are determined by the psychological significance of the stimulus. The P3 is a positive wave that occurs when a subject detects an informative task-relevant stimulus. The P3 amplitude and latency are affected by the various factors as subjective probabilites, stimulus meaning and information transmission. It is suggested that P3 wave is associated with the decision making, cognitive or perceptual closure, memory updating and transfer of information to consciousness etc. Although the intracerebral origin of the P3 wave is not known, the P3 may have multiple intracerebral generators. The CNV is a slow potential shift occuring during the foreperiod, between warning and response signals, in a reaction time experiment. It is related to expectancy, preparation etc. The abnormal findings of P3 wave and CNV in various psychiatric disorders are also discussed.

• Proceedings of the Korean Vacuum Society Conference
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• 2015.08a
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• pp.168.2-168.2
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• 2015

We observed the temperature-dependent evolution and behavior of P3HT type-II phase during a real time annealing process from a cryo-cooled low temperature in the absence and presence of an Al electrode. A poly (3-hexylthiophene) (P3HT) Type-II phase in the P3HT:PCBM films started to form near at $-10^{\circ}C$, regardless of Al layer presence. In the absence of an Al layer, type-II phase was extinct at $30^{\circ}C$. However, the extinction temperature was extended to $50^{\circ}C$ in the presence of the Al layer. Simultaneously, combined with the type-II phase, a 1:3 ordered P3HT type-II (1/3,0,0) super-lattice peak evolved. These type-II domains tended to be formed near the Al electrode layer with higher aligned status than host P3HT crystals.

• Journal of Microbiology and Biotechnology
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• v.12 no.6
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• pp.943-949
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• 2002

It has been proposed that chitin synthase 3 (CHS3)-nediated chitin synthesis during the vegetative cell cycle is regulated by chitin synthase 4 (CHS4) of Saccharomyces cerevisiae. To investigate direct protein-protein interaction between the coding products of these two genes, a domain of Chs3p that is responsible for interaction with Chs4p was identified, using the yeast two-hybrid system. This domain of 54 amino acids, termed MIRC3-4 (Maximum Interacting Region of Chs3p with Chs4p), is well conserved among CHS3 homologs of various fungi. Some mutations in MIRC3-4 resulted in a decrease in the enzymatic activity and chitin contents. Chs3p carrying those mutations exhibited weak interactions with Chs4p, when assayed by the yeast two-hybrid system. Surprisingly, all the mutants were sensitive to Calcofluor regardless of changes in enzymatic activities or chitin contents. This report deals with a core region in MIRC3-4 that affects the interaction with Chs4p.

• Applied Chemistry for Engineering
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• v.31 no.5
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• pp.539-544
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• 2020

A three-dimensional (3D) porous polyaniline (PANI) film was fabricated by a combined photo-and soft-lithography technique based on a large-area nanopillar array, followed by a controlled chemical dilute polymerization. The as-obtained 3D PANI film consisted of hierarchically interconnected PANI nanofibers, resulting in a 3D hierarchical nanoweb film with a large surface and open porous structure. Using electrochemical measurements, the resulting 3D PANI film was demonstrated as a flexible pH sensor electrode, exhibiting a high sensitivity of 60.3 mV/pH, which is close to the ideal Nernstian behavior. In addition, the 3D PANI electrode showed a fast response time of 10 s, good repeatability, and good selectivity. When the 3D PANI electrode was measured under a mechanically bent state, the electrode exhibited a high sensitivity of 60.4 mV/pH, demonstrating flexible pH sensor performance.

• Journal of Korean society of Dental Hygiene
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• v.7 no.4
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• pp.495-508
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• 2007

This study, to investigate the state of PVW among the clinical dental hygienists and its determinants, has polled 322 clinical dental hygienists working in Daegu, Kyung buk province, and Ulsan. Data were collected by self-administrated questionnaire. A SPSS 12.0 for Windows was used for statistical analysis. The obtained results were as follows: 1. The average of PVW among the respondents was 3.43. 2. The area average of PVW determinants was as follows; job significance, 3.31, process efficiency, 3.42, product usefulness, 3.32, vision realizability, 3.53, social recognition, 3.23 and the total average, 3.36. 3. The married have higher PVW than the unmarried in all areas(p=.012, p=.008, p=.036, p=.007). 4. As for working experience, in the case of perceived self value, those having 1~2 years experience have the highest PVW(p=.000), apart from perceived self value, those having over 6 years experience have the highest PVW in all areas(p=.015, p=.001, p=.002). Relating to the task, those working in the patient consulting and managing part have the highest PVW, relating to the annual salary, those having over 25 million won have the highest PVW(p=.000, p=.000, p=.001, p=.000). 5. The relationship between PVW and PVW determinants, in all respects, is meaningful, so it was found that the higher determinants are, the higher PVW is. 6. The whole explanation variate of PVW determinants was meaningful in PVW, perceived self value, value fulfillment emotion, respectively representing 38.8%, 55.6%, 61.5%(pE.001). PVW of clinical dental hygienists should be considered as a significant criterion of indivisual and organizational effectiveness. To improve effectually PVW of the clinical dental hygienists, there is need to establish culture in a system of hospital that redound to their social recognition.