• Journal of Animal Science and Technology
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• 제64권5호
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• pp.854-862
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• 2022

The purpose of this study is to determine the impact of different levels of crude protein (CP) diets supplemented with dietary protease on the growth performance and nutrient digestibility of the weanling pigs. In a 5-week study, 100 crossbred ([Landrace × Yorkshire] × Duroc) of weaner pigs that have an average initial body weight (BW) of 7.17±1.06 kg were assigned to one of four dietary treatments with 5 replications and 5 pigs (3 gilts and 2 castrated male pigs) per pen in a randomized complete block design. The dietary treatments were as follows: Phase 1: CON: basal diets (20.60% CP); low protein (LP): CON - 0.30% CP; PLP1: (CON - 0.30% CP) + 0.05% protease; PLP2: (CON - 0.50% CP) + 0.05% protease. Phase 2: CON: basal diets (18.88% CP); LP: CON - 0.30% CP; PLP1: (CON - 0.30% CP) + 0.05% protease; PLP2: (CON - 0.50% CP) + 0.05% protease. The addition of protease to low CP diets significantly increased the feed conversion ratio (FCR) (p = 0.039), BW (p = 0.046), average daily gain (ADG) (p = 0.049), and average daily feed intake (ADFI) tended to increase (p = 0.053) in the young pigs during phase 1. However, FCR tended to increase throughout the experiment but did not change during phase 2, whereas BW, ADG, and ADFI stayed unchanged throughout phase 2 and overall. There was no significant difference in dry matter, nitrogen (N), and gross energy of nutrient digestibility in all phases and overall in weaned pigs with low CP when protease was fed. In contrast, adding protease to the low CP diets increased the tendency of N digestibility (p = 0.059) during phase 1. It is concluded that dietary protease supplementation tended to increase N retention during the first phase of the weaning period, hence increasing piglet performance.

• Bulletin of the Korean Chemical Society
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• 제35권8호
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• pp.2311-2316
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• 2014

Conformations and vibrational frequencies of the racemic (2RS,3RS)-5-amino-3-(4-phenylpiperazin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol-(I) [(2RS,3RS)-(I)], a precursor of benzovesamicol analogues, have been carried out using various DFT methods (M06-2X, B3LYP, B3PW91, PBEPBE, LSDA, and B3P86) with basis sets of 6-31G(d), 6-31+G(d,p), 6-311+G(d,p), 6-311++G(d,p), cc-pVTZ, and TZVP. The LSDA/6-31G(d) level of theory shows the best performance in reproducing the X-ray powder structure. However, the PBEPBE/cc-pVTZ level of theory is the best method to predict the vibrational frequencies of (2RS,3RS)-(I). The potential energy surfaces of racemic pairs (2RS,3RS)-(I) and -(II) are obtained at the LSDA/6-31G(d) level of theory in the gas phase and in water. The results indicate that (2RS,3RS)-(I) are more stable by ~0.75 kcal/mol in energy than (2RS,3RS)-(II) in water, whereas conformer AIIg and BIIg are more stable by ~0.04 kcal/mol than AIg in gas phase. In particular, the hydrogen bond distances between the N of piperazine and the OH of tetrahydronaphthalen become longer in gas, compared with those in the water phase. Vibrational frequencies calculated at the PBEPBE/cc-pVTZ level of theory in the gas phase are larger than those in water, whereas their intensities in the gas phase are weaker than those in water.

• 한국환경농학회지
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• 제28권3호
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• pp.274-280
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• 2009

제초제 bentazon과 그 대사산물들의 토양흡착 양상을 Freundlich, Langmuir 그리고 linear isotherm을 이용하여 파악하고 기능이 다른 흡착제들과의 흡착특성을 조사하였다. 토양에 대한 bentazon의 $K_f$ = 0.55 L/kg, $Q^0$ = 3.97mg/kg, Kd = 0.18 L/kg 그리고 $K_{oc}$ = 18 L/kg로 나타났다. Deisopropylbentazon을 제외한 다른 대사산물들의 토양 흡착량은 bentazon보다 많았으며 특히 8-hydroxybentazon의 경우 $K_f$ = 316.5 L/kg, $Q^0$ = 3,448 mg/kg, $K_d$ = 29.7 L/kg 그리고 $K_{oc}$ = 2,970 L/kg으로 토양 중에서 대부분이 흡착되는 것으로 나타났다. 여러 기능을 가진 SPE 충진제를 이용하여 bentazon과 그 대사산물들의 흡착양상을 확인한 결과 bentazon, deisopropylbentazon 및 8-hydroxybentazon은 $NH_2$와 anion exchange phase에 친화성이 큰 것으로 나타났다. N-methylbentazon의 경우 $C_{18}$에 큰 친화력을 보였으나 normal phase인 silica gel에는 상대적으로 다른 화합물보다 친화력이 낮았다. IBA는 silica gel, COOH 그리고 cation exchange phase에 강한 흡착을 보였으며 상대적으로 $NH_2$ 그리고 anion exchange phase에는 친화력이 낮았다. 2-Aminobenzoic acid의 경우 pH 3.0에서는 COOH, cation exchange phase에 많은 retention을 보였으며 pH 7.0에서는 $NH_2$, anion exchange phase에 큰 흡착량을 보였다.

• Clinical and Experimental Pediatrics
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• 제62권3호
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• pp.85-89
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• 2019

Purpose: We compared thyroid hormone profiles in children with nephrotic syndrome (NS) during the nephrotic phase and after remission. Methods: This study included 31 pediatric NS patients. The thyroid hormone profiles included serum levels of triiodothyronine (T3), thyroxine (T4), thyroid-stimulating hormone (TSH), and free T4. Results: Of the 31 patients, 16 (51.6%) showed abnormal thyroid hormone profiles: 6 had overt hypothyroidism, 8 had subclinical hypothyroidism, and 2 had low T3 syndrome. The mean serum T3, T4, and free T4 levels in the nephrotic phase and after remission were $82.37{\pm}23.64$ and $117.88{\pm}29.49ng/dL$, $5.47{\pm}1.14$ and $7.91{\pm}1.56{\mu}g/dL$, and $1.02{\pm}0.26$ and $1.38{\pm}0.23ng/dL$, respectively; the levels were significantly lower in the NS nephrotic phase (P=0.0007, P<0.0001, and P=0.0002). The mean serum TSH levels during the nephrotic phase and after remission were $8.05{\pm}3.53$ and $4.08{\pm}2.05{\mu}IU/mL$, respectively; they were significantly higher in the nephrotic phase (P=0.0005). The urinary protein/creatinine ratio during the nephrotic phase was significantly correlated with serum T3, T4, and free T4 levels (r=-0.5995, P=0.0032; r=-0.5797, P=0.0047; r=-0.5513, P=0.0078) as well as with TSH levels (r=0.5022, P=0.0172). A significant correlation was found between serum albumin and serum T3 levels during the nephrotic phase (r=0.5385, P=0.0018) but not between serum albumin and T4, TSH, or free T4 levels. These significant correlations all disappeared after remission. Conclusion: Abnormal thyroid hormone profile findings were observed in 51.6% of pediatric patients with NS. Thyroid hormone levels normalized after remission, regardless of levothyroxine therapy.

• 한국통신학회논문지
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• 제31권4C호
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• pp.451-457
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• 2006

피어-투-피어(P2P) 네트워크는 개방적, 평면적, 자율적 특성으로 인하여 참여 피어들의 악의적인 공격에 근원적으로 취약하다. 본 논문에서는 부트스트래핑(bootstrapping) 단계 및 온라인 단계에서의 악의적 피어들의 공격을 효율적으로 방어하는 문제를 다룬다. 본 논문은 부트스트래핑 단계에서 네트워크의 신뢰성 있는 노드를 이용하여 새로 가입하는 피어에게 ID 관련 정보를 안전하게 부여하는 멤버쉽 처리 프로토콜을 제시한다. 이 신뢰성 있는 노드들은 새로운 피어들이 네트워크에 참여할 때만 사용되곤 그 이외의 P2P 동작에는 관여하지 않는다. 온라인 단계에서의 공격에 대하여 본 논문에서는 P2P 오버레이를 통해 전송되는 메시지의 구조를 제안하여, 메시지 변경, 재생 공격 및 잘못된 정보를 가지는 메시지 공격들의 검출이 용이해지도록 한다 제안한 기법들은 함께 적용되어 악의적 피어들의 속임수를 억제함으로써 피어들로 하여금 네트워크의 프로토콜을 준수하게 만든다. 제안 기법들은 기본적 P2P 오버레이 모델을 가정하여 비구조적 및 구조적의 다수 P2P 네트워크들에 적용될 수 있다.

• 한국경영과학회:학술대회논문집
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• 한국경영과학회 2001년도 추계학술대회 논문집
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• pp.21-24
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• 2001

This study is concerned with the development of efficient p-median approach to nondegenerate cell formation(CF) in group technology(GT) manufacturing. Unlike most of existing CF methodologies allowing degenerate cells or families that contains no parts or machines, this study attempts to find cell configuration where each machine cell contains at least two or more machines processing at least two or more parts so as to fully utilize the similarity in designing and processing parts. Nondegenerate CF seeks to minimize both the exceptional elements outside the diagonal block and the voids within the diagonal block. To find nondegenerate cells, a two-phase p-median methodology is proposed. In phase 1, the classical p-median model is implemented to find initial cells. In phase 2, bottleneck machines and parts are reassigned until no further degenerate cells and families are found. Test results on moderately medium-sized CF problems show the substantial efficiency of the proposed approach.

• 한국세라믹학회지
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• 제32권10호
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• pp.1123-1130
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• 1995

In the preparation of manganese zinc ferrite powders by alcoholic dehydration of citrate/formate solution. The effect of pH change on precipitation was investigated. The pH range for obtaining stable precipitates was studied. The glassy phase was obtained when the pH value of solution is higher than 5, and the formation mechanism of glassy phase was suggested. Below pH 5, the stable precipitates were formed, and the optimal pH was 2. Formation of glassy phase was accounted for the change of surface charge by pH change. The change of surface charge is caused by the interparticular agglomeration. The precipitate was redissolved into the water on the surface of precipitate itself and through the polymerization, it agglomerated. This mechanism is tought to be similar to that of viscous flow.

• 한국세라믹학회지
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• 제33권3호
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• pp.362-370
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• 1996

Kalsilite (KAlSiO4) system undergoes a displacive phase transition from hexagonal phase with p63 space group to the phase with P63mc at 886$^{\circ}C$. The flux composition having kalsilite :K2O:B2O3=1:2:2 has enabled the growth of hexagonal kalsilite with the size of 0.5~1 mm at a slow cooling rate (0.3$^{\circ}C$/hr). On decreasing the cooling rate the size has increased and pyramidal (1011) faces are newly developed with the shape of (0001) and (1010) faces. Upon stirring (1011) faces are degraded. The space group of O1 and O2 are P21221 and C2221 respectively. Their orthorombic modification O1 and O2 are synthesized at relatively low and high temperature respectively.

• 한국환경과학회지
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• 제4권2호
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• pp.223-232
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• 1995

액체막의 운반체로 사용할 새로운 2개의 거대고리화합물을 합성하였다. 이들 결과들은 이 시스템을 구성하는데 있어서 이론의 응용성을 증명하여 준다. source phase의 공존이온으로서 $SCN^-$,$I^-$ 및 $Cl^-$이온을 그리고 receicing phases에서 $S_2O_3^{2-}$와 $P_2O_7^{4-}$을 이용한 액세막계로서부터 중금속 이온들에 대한 선택적 수송효율을 검토하였다. source phase의 M(II)이 $Cd(SCN)_2$$(P[SCN^-]= 0.40M)$, $Hg(SCN)_2([SCN^-]=0.40M)$, Pd(CN)$([CN^-]= 0.40M)$일때 M(II)의 수송율은 최대값을 나타낸다. 각가의 경쟁 양이온에 대한 Cd(II)이나 Pd(II)은 source phase가 00.3M-$S_2O_3^{2-}$이나 0.3M-$P_2O_7^{4-}$ 일때 가장 잘 분리된다.이 연구의 결과에서, 이 액체막계에서 효과적인 거대고리-매질수송을 하기 위해서는 두개의 규칙이 반드시 필요하다. 첫째, tiluence중으로 $M^{n+}$이온이 효과적으로 추출되고, 즉 만일 $M^{n+}$ 거대고리화합물 상호작용에 대한 logK값과 $M^{n+}$-거대고리화합물($L_1$이나 $L_2$)의 상호작용에 대한 logK값의 비가 충분히 크다면 receiving phase와 toluene의 접촉면으로부터 쉽게 중금속이온($Cd^{2+}$,$Pb^{2+}$ 및 $Hg^{2+}$)들이 떨어져 나온다. $L_1$(3,5-benzo-10,13,18,21-tetraoxa-1,7-diazabicyclo(8,5,5)eicosnan)은 $Cd^{2+}$ 과 $Pb^{2+}$ 이온과 안정한 착물을 형성한다. 그리고 $L_1$은 수용액중에서 용해하기가 매우 어렵다. 그리고 $Cd^{2+}$$L_1$나 $Pb^{2+}$$L_1$착물은 $Cd^{2+}-{(S_2O_3)}_2^{2-}$나 $Pd^{2+}-P_2O_7^{4-}$착물보다 비교적 불안정하다. 다른 한편으로 $Hg^{2+}-L_1$착물의 안정도는 $Hg^2-{2+}-(S_2O_3)_2^{2-}$이나 $Pb^{2+}-P0_2O_7^{4-}$의 그것보다 그리고 $L_2$(5,8,15,18,23,26-hexaoxa-1,12-diazabicyclo(10,8,8)octacosan)의 tuluene에 대한 분배계수는 $L_1$의 그것보다 훨씬 작다. 따라서 $Hg^{2+}$-$L_1$이나 $M^{n+}$이나 $M^{n+}-L-2(M^{2+}=Cd^{2+}, Pb^{2+}$이나 $Hg^{2+})$의 안정도수상수가 매우 큼에도 불구하고 이들 양이온의 수송량은 매우 적다.

• 대한수의학회지
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• 제27권2호
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• pp.347-359
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• 1987

To investigate the changes of pituitary gland associated with ovarian cyst in Korean native cattle, pituitaries and ovaries were collected from 54 Korean native cattle at abbatoir. Pituitaries were stained with HerIant pituitary stain method and all the tissues were examined under light microscope. The results obtained were summarized as follows; 1. The delta cells and beta cells in the pars distalis were dull blue and violet in colors respeetively. Basophil size in the follicular phase and pregnant groups was larger than those of luteal phase and ovarian dysfunction groups. 2. The numbers of delta cells in the pars distalis of follicular cyst group were larger than those of remaining groups (p<0.01). 3. The distribution of delta cells in the acidophil zone was greater than that in the basophil zone of the follicular cyst and follicular phase groups. 4. The granulations of delta cells were more intensive in follicular cyst, follicular phase and pregnancy groups than in luteal phase and ovarian dysfunction groups (p<0.01). 5. The numbers of beta cells in follicular phase and ovarian dysfunction groups were larger than those in luteal phase and follicular cyst groups respectively (p<0.01). 6. In all groups, the distribution of beta cells was greater in basophilic zone than in acidophilic zone (p<0.01).