• Korean Journal of Animal Reproduction
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• v.18 no.1
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• pp.1-6
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• 1994

The effects of exogenous estrogen on growth, mammary development, and the age at which the first estrous symptoms are detected were investigated for the first time in Korean native heifers at 6 months of age. At 90 days after treatment, weight gains of heifers implanted with 10 mg of estradiol were not different from those of the control heifers. However, weight gams of heifers implanted with 20 mg of estradiol were significantly increased at 90 days by 18%, relative to control values. At 180 days, cumulative weight gains of heifers implanted with either 10 mg or 20 mg of estradiol averaged 6.7% or 17.8%, respectively, greater than controls. But these values were not statistically significant. Regardless of dosage, teat diameter gains in the treatment groups were significantly increased at 90 days about 159%, relative to controls. Cumulative teat diameter gains in the heifers implanted with either 10 mg or 20 mg of estradiol were also significantly increased at 180 days by 100% or 128%, respectively, compared to controls. Teat length gains in the heifers implanted with either 10 mg or 20 mg of estradiol were significantly increased at 90 days by 200% and 295%, respectively, compared to controls. Cumulative teat length gains in the heifers implanted with either 10 mg or 20 mg of estradiol were significantly 265% and 325%, respectively, higher than controls. The heifers implanted with either 10 mg or 20 mg of estradiol showed a significant increase in teat volume gains at 90 days of 282% or 246%, respectively, over those of the control heifers. Cumulative teat volume gains in the heifers implanted with either 10 mg or 20 mg of estradiol were significantly increased at 180 days by 251% and 244%, respectively, compared to control values. However, there were no significant differences m gams of teat diameter, length and volume between heifers implanted with 10 mg and 20 mg of estradiol regardless of 90 days or 180 days. Heifers implanted with 10 mg or 20 mg of estradiol showed the first estrus 20 or 124 days, respectively, faster than controls. Overall, These data strongly suggest that estradiol implantation into heifers stimulates growth and mammary development and hasten the age at which the first estrus in Korean native heifers is observed.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.8 no.2
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• pp.31-43
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• 2002

The subjects of this study were 15 woman soccer players and 15 untrained woman students at H-Cheju University. Each subject was measured on the muscle strength and peak torque of knee extensors and knee flexors with isokinetic load ($60^{\circ}$/sec, $180^{\circ}$/sec). The results were as follows: 1. There was no significant difference between right and left leg strength measured isokinetically in each group. 2. The peak torque of knee extensors and flexors was significantly higher in scoccer players than untrainded students (p<0.001). 3. For the angle of knee joint showing the highest peak torque, there was significant difference between soccer players and untrained students in knee extensors(p<0.05) and right flexors (p<0.01). 4. For knee H/Q ratio, there was significant difference between two groups(p<0.05). 5. For the total work and average power at $180^{\circ}$/sec, there was significant difference between two groups in knee extensors(p<0.001) and flexors(p<0.01). 6. In soccer players at $60^{\circ}$/sec, there were significant correlations between peak torque and height and between peak torque and weight.(p<0.001). 7. For the muscular contraction velocity at $60^{\circ}$/sec, there was significant difference between two groups in flexors (p<0.01). 8. For the muscular indurance at $180^{\circ}$/sec in extensors and flexors, there was no significant difference between two groups(p<0.05). In conclusion, there were significantly higher in peak torque, contraction velocity, knee joint's angle with the highest peak torque, H/Q ratio, total work and average power in woman scoccer player than general students. But there was no significant difference in muscular endurance. Soccer performance is based on the various components including muscular endurance that is one of the most important components. So it is necessary that the training method to improve the various components (especially including muscular endurance) should be done.

• Korean Journal of Environmental Biology
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• v.25 no.4
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• pp.342-348
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• 2007

In a previous study, a new antibacterial activity was found from Paenibacillus polymyxa DY1 isolated from Korean soil, which showed a good growth inhibition against various multidrug resistant enteric bacteria. Thus the effect of nutritional factors and physicochemical conditions on the growth of P. polymyxa DY1 cells and the production of antibacterial activity were evaluated in this study. For the growth of P. polymyxa DY1 cells the optimum condition reaches by incubating at $35^{\circ}C$ for 48 hours by shaking at 180 rpm in the basal medium containing 0.6% dextrose, 1.4% ammonium phosphate dibasic, 0.9% peptone, 2.4% glutamine, and 2 mM sodium molybdate with initial pH 8.0. A maximum level of antibacterial activity was obtained when P. polymyxa DY1 was incubated at $35^{\circ}C$ for 48 hours by shaking at 180 rpm in the basal medium with initial pH 8.0 containing 1% dextrose, 1.5% ammonium sulfate, 1.1% casamino acid, 1.9% aspartic acid, and 2 mM ferrous sulfate.

• Toxicological Research
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• v.27 no.2
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• pp.77-83
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• 2011

The objective of this study was to evaluate and compare the antitumor activity of different solvent fractions (ethanol, dichloromethane, ethyl acetate, butanol and water) of the Auricularia auricula-judae 70% ethanol extract on the P388D1 macrophage and sarcoma 180 cells. A dose-dependent antitumor activity of each solvent fraction (from 0.01 mg/ml to 0.3 mg/ml) was shown against both cell types. These cytotoxic effects of all the tested fractions were confirmed on the MTT and SRB assays, without statistical differences each other. $IC_{50}$ value of dichloromethane fraction was 94.2 ${\mu}g/ml$ against sarcoma 180 cells lower than any other solvent fractions. The potent antitumor effect of the dichloromethane (DCM) fraction was also found against solid tumor in BALB/c mice. The splenomegaly and higher splenic index were found in tumor-bearing mice, with the DCM fraction returning to the negative control values. Thus, the results indicated the dichloromethane fraction may have potential ingredients as antitumor candidates.

• The Journal of Advanced Prosthodontics
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• v.8 no.4
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• pp.285-289
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• 2016

PURPOSE. This study evaluated the effect of chemical surface treatment using methyl formate-methyl acetate (MF-MA) solution on the tensile bond strength between acrylic denture teeth and auto-polymerized acrylic resin. MATERIALS AND METHODS. Seventy maxillary central incisor acrylic denture teeth for each of three different brands (Yamahachi New Ace; Major Dent; Cosmo HXL) were embedded with incisal edge downwards in auto-polymerized resin in polyethylene pipes and ground with silicone carbide paper on their ridge lap surfaces. The teeth of each brand were divided into seven groups (n=10): no surface treatment (control group), MF-MA solution at a ratio of 25:75 (v/v) for 15 seconds, 30 seconds, 60 seconds, 120 seconds, 180 seconds, and MMA for 180 seconds. Auto-polymerized acrylic resin (Unifast Trad) was applied to the ground surface and polymerized in a pressure cooker. A tensile strength test was performed with a universal testing machine. Statistical analysis of the results was performed using two-way analysis of variance (ANOVA) and post-hoc Dunnett T3 test (${\alpha}$=.05). RESULTS. The surface treatment groups had significantly higher mean tensile bond strengths compared with the control group (P<.05) when compared within the same brand. Among the surface treatment groups of each brand, there were no significantly different tensile bond strengths between the MF-MA groups and the MMA 180 second group (P>.05), except for the Yamahachi New Ace MF-MA 180-second group (P<.05). CONCLUSION. 15-second MF-MA solution can be an alternative chemical surface treatment for repairing a denture base and rebonding acrylic denture teeth with auto-polymerized acrylic resin, for both conventional and cross-linked teeth.

• Preventive Nutrition and Food Science
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• v.6 no.3
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• pp.187-191
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• 2001

Effects of kochujang (Korean red pepper soybean paste) extracts on tumor formation, natural killer (NK) cell activity in spleen and glutathione S-transferase (GST) activity in liver were investigated in the sarcoma-180 cell transplanted mice. Inhibitory effects of these samples on lung metastasis of colon 26-M3.1 cells were also evaluated in the Balb/c mice. The injection of methanol extracts from traditional kochujang I (TK I, 0-day fermented), II (TKII, 6-month fermented), commercial kochujang (CK, 1-month fermented) and red pepper powder (RPP) significantly reduced tumor formation in Balb/c mice (p<0.05), TKII decreased tumor growth by 46% compared with control, resulting in the smallest tumor weight. The transplantation of sarcoma-180 cells increased the spleen/body weight ratio of Balb/c mice, while TKI and TKll significantly decreased this index (p<0.05). The effect of TKll and CK, fermented kochujang, on the NK cell activity of splenocytes was higher than that of sarcoma-180 cells transplanted control group. TK II recovered the activity of hepatic GST that was decreased by the transplantation of sarcoma- 180 cells in to the mice. All kochujang-treated mice had significantly fewer lung metastatic colonies than control mice. TKII was the most effective in inhibiting lung metastasis of colon 26-M3.1 cells. These results indicated that optimally ripened (6-month) TK had more suppressive effects on tumor formation and lung metastasis than RPP and kochujang without fermentation and commercially prepared kochujang in mice.

• Journal of Gifted/Talented Education
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• v.23 no.4
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• pp.593-614
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• 2013

The purpose of this study was to analyze the research ethics elementary and secondary gifted students enrolled in science-gifted education center of university and to get the implications of research ethics education. 180 elementary and secondary gifted students and 180 general students were participated. The results obtained from this study were as follows: First, the item, such as 'The researchers must have self-esteem and responsibility in their study', both the gifted students and the general students showed the highest perception. On the contrary, the item 'I think that it is right to exclude the person who didn't participate in research' both the gifted students and the general students showed the lowest perception. And gifted students' perception on research ethics was higher than the general students' on the whole. There was a statistically significant difference between two groups(p<.05). Second, the scientifically gifted students' research ethics in 'basic attitude of the researchers' was significantly higher than mathematically gifted students' and IT gifted students' (p<.05). Third, there was a statistically significant difference between the elementary gifted students and secondary gifted students in 'ethics of thought and expression' (p<.05). Fourth, experience in research ethics education and the number of research experience was significantly effect on perception of research ethics. There was a statistically significant interaction effect between gifted students and general students in 'science, technology, biomedical research ethics' items(p<.05).

• Journal of Environmental Science International
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• v.13 no.3
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• pp.289-295
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• 2004

The objective of this study is to delineate removal efficiency of the MTBE in solution by $TiO_2$ photocatalytic degradation as a function of the following different experimental conditions: Initial concentration of MTBE, air flow rate in solution, $H_2O_2$ dosage and pH of the solution. Photodegradation rate was increased with decreasing initial concentration of MTBE. The removal efficiency was 82% after 180 min in the case of MTBE concentration of 100 mg/L but 100% after 180 min in the case of 20 mg/L. Removal efficiency was increased with increasing pH, $H_2O_2$ dosage and air flow rate in solution.

• Food Science of Animal Resources
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• v.34 no.5
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• pp.647-655
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• 2014

Obesity is strongly associated with several metabolic and chronic diseases and has become a major public health problem of worldwide concern. This study aimed to investigate the physiological characteristics and anti-obesity effects of Lactobacillus plantarum Q180. Lactobacillus plantarum Q180 was isolated from the faces of healthy adults and found to have a lipase inhibitory activity of $83.61{\pm}2.32%$ and inhibited adipocyte differentiation of 3T3-L1 cells ($14.63{\pm}1.37%$) at a concentration of $100{\mu}g/mL$. The strain was investigated for its physiological characteristics. The optimum growth temperature of L. plantarum Q180 was $37^{\circ}C$. Lactobacillus plantarum Q180 showed higher sensitivity to novobiocin in a comparison of fifteen different antibiotics and showed the highest resistance to rifampicin, polymyxin B and vancomycin. The strain showed higher ${\beta}$-galactosidase and N-acetyl-${\beta}$-glucosaminidase activities. It also did not produce carcinogenic enzymes such as ${\beta}$-glucuronidase. The survival rate of L. plantarum Q180 in MRS broth containing 0.3% bile was 97.8%. Moreover, the strain showed a 97.2% survival rate after incubation for 3 h in pH 2.0. Lactobacillus plantarum Q180 was displayed resistance to Escherichia coli, Salmonella Typhimurium and Staphylococcus aureus with rates of 55.6%, 38.0% and 47.6%, respectively. These results demonstrate that L. plantarum Q180 has potential as a probiotic with anti-obesity effects.

• Journal of the Korean Chemical Society
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• v.24 no.2
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• pp.178-180
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• 1980