• 제목/요약/키워드: P-delta effects

검색결과 397건 처리시간 0.034초

인삼 복용 전후 체표온도의 변화에 관한 임상적 연구 (A Clinical Study on the Effect of Ginseng to Control Superficial Body Temperature)

  • 최가야;조정훈;장준복;이경섭
    • 대한한방체열의학회지
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    • 제2권1호
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    • pp.49-55
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    • 2003
  • In Oriental medicine, Ginseng had been used for many diseases widely. It's main effects are suppling Qi and Promoting metastasis. The objective of this study is to examine the effect of Ginseng on control of body temperature. We conducted this study with 24 volunteers who had no problem in their health from November 2002 to January 2003. The body temperature were measured by DITI and thermometer before taking Ginseng and after 30minutes of the taking Ginseng extract 15g. We observed the difference of temperature among face chest and upper abdomen. All data were coded for computer analysis and significance were tested by Paired t-test and independent-t-test. According to our study, the axillary temperature show no signifiant change between two groups. The difference of temperature$({\Delta}T)$ between face and upper abdomen significantly increase after taking Ginseng extract(p<0.01). The difference of temperature$({\Delta}T)$ between face and chest significantly increase after taking Ginseng extract(p<0.05).

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Human Glutathione S-Transferase P1 Suppresses MEKK1-mediated Apoptosis by Regulating MEKK1 Kinase Activity in HEK293 Cells

  • Zhao, Xin;Fan, Yumei;Shen, Jiayin;Wu, Yifan;Yin, Zhimin
    • Molecules and Cells
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    • 제21권3호
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    • pp.395-400
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    • 2006
  • Glutathione S-transferase P1 (GSTP1) plays an important role in detoxification and the metabolism of xenobiotics. Here we show that GSTP1 also regulates the MEKK1-MKK7 signaling pathway. Over-expression of GSTP1 in HEK293 cells inhibited both ${\Delta}MEKK1$- and etoposide-induced apoptosis, and inhibited procaspase-3 activation and PARP cleavage. MEKK1- induced apoptosis requires both its kinase activity and proteolytic cleavage. ${\Delta}MEKK1$ activity was inhibited by over-expression of GSTP1 in vivo and MEKK1 kinase activity was also inhibited by GSTP1 in vitro when assayed with bacterially-expressed MKK7(KM) protein as substrate. GSTP1 inhibition of etoposide-induced cell apoptosis was mainly due to its ability to suppress MEKK1 kinase activity. The glutathione-conjugating activity of GSTP1 was essential for the above effects. These findings provide insight into the mechanism by which GSTP1 protects cells from genotoxin-induced apoptosis.

반복하중을 받는 강재 브레이싱의 거동에 관한 해석적 연구 (A Study on the Analysis of Steel Bracing Behaviour Subjected to Cyclic Loads)

  • 구민세;김병석;김일곤
    • 전산구조공학
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    • 제2권3호
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    • pp.69-75
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    • 1989
  • 브레이싱재를 사용하는 목적은 본 골조체계 즉 기둥과 보에 비해 단면(강성)이 작은 부재로 보강하여 횡력에 대한 강성효과를 크게 향상시키기 위함이다. 브레이싱재의 단면이 기둥과 보의 단면에 비해 월등히 작기 때문에 압축력에 의한 좌굴의 위험성과 휨량의 크기에 비례하여 부재 중앙에 발생되는 추가 모멘트(P-.DELTA. Effect)에 의한 불리한 영향 및 해석상의 어려움 때문에 브레이싱의 설계에 있어서 브레이싱재는 압축력을 받지 않는 것으로 간주하여 왔다. 그러나 최근 들어 구조물 해석에 정확도가 요구되어짐에 따라 브레이싱재의 정확한 거동에 대한 연구가 실험을 통해 활발히 진행되어 왔고, 특히 탄성한계를 지난 소성상태에서 반복하중에 의한 거동 규명이 큰 관심을 끌고 있다. 본 논문에서는 반복하중을 받는 강재 브레이싱재의 비선형 거동을 해석적 방법에 의해 규명했고, 그 결과를 실험결과와 비교하였다.

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접합부 비선형 거동을 고려한 강구조 비가새 골조의 안정성 (The Stability of Steel Unbraced Frames Considering Nonlinear Behavior of Connections)

  • 김희동
    • 한국강구조학회 논문집
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    • 제17권4호통권77호
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    • pp.469-479
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    • 2005
  • 강구조 비가새 골조의 접합부로서 반강접합부를 적용하게 되면 접합부의 비선형적인 모멘트-회전각 관계는 강구조 비가새 골조의 거동($P-\Delta$ 효과) 및 안정성에 영향을 미치게 된다. 따라서 본 연구에서는 이러한 접합부 비선형 거동이 골조의 거동 및 안정성에 미치는 영향을 2차 비탄성 해석을 통하여 고찰하고, 안정성에 영향을 미치는 주요 인자 및 그 경향들을 분석하였다. 연구 결과 접합부의 비선형 거동은 골조의 안정성에 직접적인 영향을 미치는 것으로 나타났으며 주요 영향인자는 접합부의 회전강성, 반강접합부의 적용 위치 등으로 나타났다.

Effect of the Injection Parameters on Diesel Spray Characteristics

  • Song Kyu Keun;Sim Sang Cherl;Jung Byong Koog;Kim Hyung Gon;Kim Jang Heon
    • Journal of Mechanical Science and Technology
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    • 제19권6호
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    • pp.1321-1328
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    • 2005
  • The characteristics of the diesel spray have affected certain aspects of engine performance, such as the power, fuel consumption, and emissions. Therefore, this study was performed to investigate the effects of various injection parameters. In order to obtain the effect of injection parameters on diesel spray characteristics, the experiment is performed by using a high temperature and pressure chamber. The behaviors of the spray are visualized by using a high speed video camera, spray angle, penetration, and various other things. The results of the experiment are summarized as follows. (1) The correlation of the spray penetration can be expressed as follows. $$0< t $$t_{b} (2) The correlation of the spray angle can be expressed as follows $$T_a=293K\;tan({\theta}/2)=0.59({\rho}a/{\rho}f)^{0.437}$$ $$T_a=473K\;tan({\theta}/2)=0.588({\rho}a/{\rho}f)^{0.404}$$ (3) The measured macro characteristics that include the spray tip penetration and spray angle corresponded with the established correlations.

행간(行間)(LR2) 전침자극(電鍼刺戟)이 적외선(赤外線) 체열진단상(體熱診斷上) 안면부(顔面部) 온도변화(溫度變化)에 미치는 영향(影響) (Effects of electroacupuncture stimulation at Xingjian(LR2) on the facial thermal change by D.I.T.I)

  • 김종욱;최성용;진경선;황우준;민상준;이순호;이상룡
    • Journal of Acupuncture Research
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    • 제21권1호
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    • pp.226-239
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    • 2004
  • Objective: Purpose of this study was to examine the effect of electroacupuncture(EA) at Xingjian(LR2) as 'Fire(火)' point of The Leg Absolute Um Liver Meridan(足厥陰肝經 : Chok-Kworum-Kan-Kyong) on the facial thermal change. Methods: Subjects of this study were 15 patients with upperpart(includes head and facial part) fever of human body and two examinations were carried out in each other day. We divided cases of two examinations into two groups. One is experimental group(N=15) that was carried out electroacupuncture stimulation at Xingjian(LR2), the other is control group(N=15) which was carried out electroacupuncture stimulation at optional point(in space between 1st and 2nd fingers) except acupuncture points of 12 meridians. We took the temperature of fixed areas on face by digital infrared thermal image(D.I.T.I.) before and after electroacupuncture stimulation. Those fixed areas on face that was taken temperature are Jingming(BL1), Sibai(ST2), Dicang(ST4), Indang, Shuigou(GV26), Chengjiang(CV24) areas. In cases of temperature of Jingming(BL1), Sibai(ST2), Dicang(ST4) areas, we applied each mean of left and right temperature to statical analysis. Results: In the group of electroacupuncture stimulation at Xingjian(LR2), temperature of every fixed areas on face fell: Jingming(BL1) area's ${\Delta}T=-0.7007{\pm}0.78642$, Sibai(ST2) area's ${\Delta}T=-0.6280{\pm}0.56439$, Dicang(ST4) area's ${\Delta}T=-0.5940{\pm}0.60179$, Indang area's ${\Delta}T=-0.7200{\pm}0.64515$, Shuigou(GV26) area's ${\Delta}T=-0.6160{\pm}0.80487$, Chengjiang(CV24) area's ${\Delta}T=-0.5627{\pm}0.72615$. In Xingjian(LR2) electroacupuncture group, each temperature of Jingming(BL1), Sibai(ST2), Indang areas showed a drop significantly in comparison with control group (p<0.05). But each temperature of Dicang(ST4), Shuigou(GV26), Chengjiang(CV24) areas did not showed a drop significantly in comparison with control group(p>0.05). Conclusions: The results mentioned above showed that electroacupuncture stimulation at Xingjian(LR2) significantly decreased the temperature on face of patients with upperpart fever of human body. In Xingjian(LR2) electroacupuncture group, especially temperature of upper part of face includes eye, cheekbone, forehead regions showed a drop significantly in comparison with control group.

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방사선과 훈증 처리된 건고추의 저장 중 부위별 색도 및 관능적 특성 (Effects of Irradiation and Fumigation on Color and Sensory Properties in the Parts of Dried Red Pepper during Storage)

  • 김병근;권영주;노정은;김정숙;김동호;권중호
    • 한국식품저장유통학회지
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    • 제11권4호
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    • pp.431-436
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    • 2004
  • 건고추의 위생화 및 검역처리와 관련하여 감마선 조사(5, 10 kGy)와 훈증처리(MeBr, $PH_3$)된 건고추의 지장 중 기계적 색도(Hunter L, a, b, ${\Delta}E$) 및 관능적 품질을 평가하였다. 건고추의 가공형태에 따른 비교에서 통고추는 실온저장 중 높은 명도(L) 값을, 분말 고추는 높은 적색도(a) 값을 유지하였다. 건고추 부위별 시료의 색도에 대한 감마선과 훈증 처리의 영향에서 처리 직후에는 전반적인 색차(${\Delta}E$) 값이 크지 않았으나, 저장 8개월 후 통고추는 $PH_3$ 훈증군이, 분말 고추는 5 kGy 조사군이 각각 높은 적색도를 보였다(p<0.05). 감마선 조사 건고추 과피의 적색도는 저장 8개월에 크게 감소하였으며, 훈증 처리된 시료에서도 유사한 변화를 보였다. 건고추 씨의 황색도(b)는 10 kGy 조사군이 가장 낮은 값을 보였으며(p<0.05), 저장 기간이 경과됨에 따라 처리군 간에 유의적인 차이가 나타나지 않았다. 통고추 및 분말고추의 관능적 품질은 상업적 조건의 감마선 및 훈증 처리에 의해 거의 변화되지 않았으며, 저장기간이 경과할수록 대조군에 비해 높은 관능평점을 보여주었다. 이 같은 결과는 감마선 및 훈증 처리 시 통고추 형태보다는 분말고추에서 보다 양호하게 나타났다.

이침(耳鍼)의 신문혈(神門穴) 자극(刺戟)이 치매환자(痴呆患者)의 뇌파(腦波)에 미치는 영향(影響) (The Effect of Auricular Acupuncture at the Shinmun on the Electroencephalogram(EEG) in patients with dementia)

  • 김미라;이고은;이상언;박인숙;박장호;노동진;김지영;박보라;류영수;강형원
    • 동의신경정신과학회지
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    • 제21권3호
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    • pp.45-64
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    • 2010
  • Objectives : The purpose of this study was to examine the effects of auricular acupuncture at the Shinmun on patients with dementia by using power spectrum analysis. Electroencephalogram(EEG) power spectrum show site-specific and state-related differences in various frequency bands. Methods : Study was carried out in 38 subjects.(31 patients with dementia and 7 normal people, 27 females and 11 males ; mean age=75.9 years old). To know the effect of auricular acupuncture at the Shinmun in patients with dementia, we measured electroencephalogram(EEG) of normal people and patients with dementia about 'before', 'after' and 'after 15 minutes' giving auricular acupuncture at the Shinmun, and compared the brain wave($\alpha$, $\beta$, $\delta$, $\theta$) of EEG 30 channels. Results : In the case of patients with dementia, in the power values of $\alpha$(alpha) band at F4, FP2, FCZ, F8, FC4 channels (p<0.05) during the Shinmun-auricular acupuncture treatment increased significantly. In $\beta$(beta) band, the power values at T8 channel(p<0.05) during the Shinmun-auricular acupuncture treatment increased significantly. In $\delta$(delta) band, the power values at F7, FP1, FZ, FP2, FCZ, C4, FC4, CP4, T8, P7, P3, O1, OZ, O2, P4, P8 channels(p<0.05) during the Shinmun-auricular acupuncture treatment decreased significantly. In $\Theta$(theta) band, the power values at O1, OZ, O2channel(p<0.05) during the Shinmun-auricular acupuncture treatment decreased significantly. Conclusions : Through these results, we concluded that auricular acupuncture at the Shinmun on patients with dementia could have effect the functional mechanism of the cerebral cortex.

Effects of different surface finishing procedures on the change in surface roughness and color of a polymer infiltrated ceramic network material

  • Ozarslan, Mehmet Mustafa;Buyukaplan, Ulviye Sbnem;Barutcigil, Cagtay;Arslan, Merve;Tuker, Nurullah;Barutcigil, Kubilay
    • The Journal of Advanced Prosthodontics
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    • 제8권1호
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    • pp.16-20
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    • 2016
  • PURPOSE. Polymer infiltrated ceramic network (PICN) materials, also called hybrid ceramics, are new materials in dental market. The manufacturer of the PICN material VITA Enamic suggests 3 different finishing procedures for this new material. In the present study, surface roughness and color differences caused from different finishing procedures of VITA Enamic were investigated. MATERIALS AND METHODS. 120 specimens were prepared in dimensions $2{\times}10{\times}12mm$ from VITA Enamic hybrid ceramic blocks with 'high translucency' and 'translucency 2M2' shades. The specimens were divided into 8 groups. For each group, different finishing procedures suggested by the manufacturer were performed. Surface roughness values were determined by a tactile portable profilometer. Color changes were evaluated using a clinical spectrophotometer. The data were analyzed using one-way ANOVA and Tukey's post-hoc comparison. The significance level was set at ${\alpha}=0.05$. RESULTS. The roughest surfaces were observed in Glaze Groups. Their surface roughness values were similar to that of the control group. Clinical Kit and Technical Kit groups did not show a statistically significant difference regarding surface roughness (P>.05). The largest color difference regarding ${\Delta}E_{00}$ was observed in Clinical Kit finishing groups. There were also statistically significant color changes between the groups (P<.05). However, all the groups showed clinically acceptable color change (${\Delta}E_{00}$<2.25) except Clinical Kit Groups (${\Delta}E_{00}$>2.25). CONCLUSION. Within the limitations of the present study, it may be suggested that finishing the VITA Enamic restorations by Technical Kit instead of Glaze and Clinical Kit gives better clinical performance in regard to surface roughness and shade matching.

지료의 제타전위 측정을 통한 형광증백제의 흡착 평가 (Adsorption Analysis of Fluorescent Whitening Agent on Cellulosic Fibers by Zeta Potential Measurement)

  • 이지영;김은혜;김철환;박종혜
    • 펄프종이기술
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    • 제47권6호
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    • pp.106-112
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    • 2015
  • Many researchers have proposed analytical methods to measure the adsorption of di-sulpho fluorescent whitening agents (D-FWAs), but practical methods for D-FWA utilization in an actual paper mill have not been established. In particular, the D-FWA adsorption behavior must be monitored in paper mills to ensure the effective use of D-FWAs. This study used the zeta-potential of pulps as an indicator of the adsorption behavior of a D-FWA. We identified the relationship between the actual adsorption of the D-FWA and the zeta-potential of the pulps as a function of D-FWA addition. zeta-potential measurements were then used to analyze the D-FWA adsorption behavior under different conditions of pulp type, conductivity, and pH. The actual adsorption of a D-FWA was proportional to the ${\Delta}zeta-potential$ of the pulps (i.e., the difference between the zeta-potential of a pulp containing no D-FWA and one containing the D-FWA). The ${\Delta}zeta-potential$ of the pulps was therefore adopted for adsorption analysis. A higher adsorption of the D-FWA was observed onto Hw-BKP than onto Sw-BKP because of the shorter fiber length and higher fines content of Hw-BKP. A high conductivity and an acidic pH decreased the D-FWA adsorption because of direct effects of high ion concentrations and low pH on the D-FWA solubility. Therefore, a D-FWA must be added to Hw-BKP under low conductivity conditions and at neutral or alkaline pH to optimize the D-FWA adsorption.